1,815 Matching Annotations
  1. Jul 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112817

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    sciencedirect.com/science/article/pii/S2211124723008288
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    Orphan quality control shapes network dynamics and gene expression
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.015

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    sciencedirect.com/science/article/pii/S0092867423006918
  4. 52.53.155.43 52.53.155.43
    Apical polarity and actomyosin dynamics regulate Hippo signaling by controlling Kibra subcellular localization
    1
    1. scibot 19 Jul 2023
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      DOI: 10.1101/2023.06.05.543736

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    52.53.155.43/32faa65cd8cc5e3ea2a2243b08a233a0e281c4f4/2023.06.05.543736v1.full-html.html
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    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
    1
    1. scibot 15 Jul 2023
      RRID:AB_262044

      DOI: 10.1016/j.celrep.2023.112812

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    sciencedirect.com/science/article/pii/S2211124723008239
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    Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.neuron.2023.06.005

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    sciencedirect.com/science/article/pii/S0896627323004658
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    The oxidative folding of nascent polypeptides provides electrons for reductive reactions in the ER
    1
    1. scibot 08 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112742

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    sciencedirect.com/science/article/pii/S2211124723007532
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    Sen1 and Rrm3 ensure permissive topological conditions for replication termination
    1
    1. scibot 07 Jul 2023
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    sciencedirect.com/science/article/pii/S2211124723007581
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    Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.molcel.2023.06.007

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    sciencedirect.com/science/article/pii/S1097276523004306
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    Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells
    1
    1. scibot 06 Jul 2023
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    sciencedirect.com/science/article/pii/S221112472300760X
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    IFITM1 inhibits trophoblast invasion and is induced in placentas associated with IFN-mediated pregnancy diseases
    1
    1. scibot 01 Jul 2023
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      DOI: 10.1016/j.isci.2023.107147

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    sciencedirect.com/science/article/pii/S2589004223012245
  12. Jun 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40
    1
    1. scibot 30 Jun 2023
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      DOI: 10.1016/j.str.2023.06.002

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    sciencedirect.com/science/article/abs/pii/S0969212623001983
  14. 52.53.155.43 52.53.155.43
    4405.full-html.html
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    1. scibot 29 Jun 2023
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      DOI: 10.1523/JNEUROSCI.2146-22.2023

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    52.53.155.43/29ab334110de858c7a6937a4817b3955d437811a/4405.full-html.html
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    Convergence of multiple RNA-silencing pathways on GW182/TNRC6
    1
    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.molcel.2023.06.001

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    sciencedirect.com/science/article/pii/S1097276523004239
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    The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity
    1
    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.immuni.2023.06.002

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    sciencedirect.com/science/article/pii/S1074761323002376
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis
    1
    1. scibot 27 Jun 2023
      RRID:AB_262044

      DOI: 10.1080/15548627.2023.2169309

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    ncbi.nlm.nih.gov/pmc/articles/PMC10283425/
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    16p11.2 CNV gene Doc2α functions in neurodevelopment and social behaviors through interaction with Secretagogin
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112691

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    sciencedirect.com/science/article/pii/S2211124723007027
  19. www.biorxiv.org www.biorxiv.org
    KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1101/2023.06.12.543777

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    biorxiv.org/content/10.1101/2023.06.12.543777v1
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    SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.isci.2023.106994

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    sciencedirect.com/science/article/pii/S2589004223010714
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    Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.039

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    sciencedirect.com/science/article/pii/S0092867423005913
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    Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
    1
    1. scibot 23 Jun 2023
      RRID:AB_262044

      DOI: 10.1016/j.molcel.2023.05.022

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    sciencedirect.com/science/article/pii/S1097276523003787
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    Phosphatidylinositol 4-kinase IIα is a glycogen synthase kinase 3-regulated interaction hub for activity-dependent bulk endocytosis
    1
    1. scibot 22 Jun 2023
      RRID:AB_262044

      DOI: 10.1016/j.celrep.2023.112633

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    sciencedirect.com/science/article/pii/S2211124723006447
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    A mitochondrial iron-responsive pathway regulated by DELE1
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.031

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    sciencedirect.com/science/article/pii/S1097276523004136
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    Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.027

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    sciencedirect.com/science/article/pii/S0092867423005779
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    ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.028

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    sciencedirect.com/science/article/pii/S1097276523003842
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    A Golgi-resident GPR108 cooperates with E3 ubiquitin ligase Smurf1 to suppress antiviral innate immunity
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112655

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    sciencedirect.com/science/article/pii/S2211124723006666
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    Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancer
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.ebiom.2023.104650

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    sciencedirect.com/science/article/pii/S2352396423002153
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aclarubicin stimulates RNA polymerase II elongation at closely spaced divergent promoters
    1
    1. scibot 17 Jun 2023
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      DOI: 10.1126/sciadv.adg3257

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    ncbi.nlm.nih.gov/pmc/articles/PMC10266722/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restored autophagy is protective against PAK3-induced cardiac dysfunction
    1
    1. scibot 17 Jun 2023
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      DOI: 10.1016/j.isci.2023.106970

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    ncbi.nlm.nih.gov/pmc/articles/PMC10265534/
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    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
    1
    1. scibot 09 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112616

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    sciencedirect.com/science/article/pii/S2211124723006277
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    Enterohemorrhagic Escherichia coli senses microbiota-derived nicotinamide to increase its virulence and colonization in the large intestine
    1
    1. scibot 09 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112638

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    sciencedirect.com/science/article/pii/S2211124723006496
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification
    1
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      DOI: 10.1021/acs.jproteome.2c00706

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    ncbi.nlm.nih.gov/pmc/articles/PMC10243116/
  34. dx.doi.org dx.doi.org
    LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL
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      DOI: 10.1158/2159-8290.CD-22-0376

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    dx.doi.org/10.1158/2159-8290.CD-22-0376
  35. www.sciencedirect.com www.sciencedirect.com
    A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders
    1
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      DOI: 10.1016/j.str.2023.05.010

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    sciencedirect.com/science/article/pii/S096921262300165X
  36. www.embopress.org www.embopress.org
    Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV
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      DOI: 10.15252/embr.202256430

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    embopress.org/doi/10.15252/embr.202256430
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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      DOI: 10.1158/1078-0432.CCR-22-3836

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    ncbi.nlm.nih.gov/pmc/articles/PMC10233356/
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    SETD7 promotes lateral plate mesoderm formation by modulating the Wnt/β-catenin signaling pathway
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      DOI: 10.1016/j.isci.2023.106917

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    sciencedirect.com/science/article/pii/S258900422300994X
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    Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
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      DOI: 10.1016/j.cell.2023.05.003

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    sciencedirect.com/science/article/pii/S0092867423005226
  40. www.science.org www.science.org
    Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis
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      DOI: 10.1126/sciimmunol.adg3196

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    science.org/doi/10.1126/sciimmunol.adg3196
  41. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deneddylating enzyme SENP8 regulates neuronal development
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      DOI: 10.1111/jnc.15797

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15797
  42. www.jneurosci.org www.jneurosci.org
    The SphK1/S1P axis regulates synaptic vesicle endocytosis via TRPC5 channels
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      DOI: 10.1523/JNEUROSCI.1494-22.2023

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    Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis
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    The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia
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    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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    Characterisation of the OTU domain deubiquitinase complement of Toxoplasma gondii
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    Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation
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    PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation
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    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
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    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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    Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence
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    The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus
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    A single-copy knockin translating ribosome immunoprecipitation toolkit for tissue-specific profiling of actively translated mRNAs in C. elegans
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    Structural basis for the Rad6 activation by the Bre1 N-terminal domain
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    Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins
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    A central chaperone-like role for 14-3-3 proteins in human cells
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    Deficiency of WTAP in islet beta cells results in beta cell failure and diabetes in mice
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    The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells
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    A combinatorial approach to uncover an additional Integrator subunit
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    Recruitment of Polo-like kinase couples synapsis to meiotic progression via inactivation of CHK-2
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    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer
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    Cell context-dependent CFI-1/ARID3 functions control neuronal terminal differentiation
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    FAM193A is a positive regulator of p53 activity
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    Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin
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    An AlphaFold2 map of the 53BP1 pathway identifies a direct SHLD3-RIF1 interaction critical for DNA repair activity
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    Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
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    Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
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    Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity
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    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
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    Epigenetic function during heroin self-administration controls future relapse-associated behavior in a cell type-specific manner
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    Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction
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    Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames
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    Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein
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    Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
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    STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice
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    Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma
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    Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control
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    Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models
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    Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules
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    The lipid transporter ORP2 regulates synaptic neurotransmitter release via two distinct mechanisms
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    Fungal CFEM effectors negatively regulate a maize wall-associated kinase by interacting with its alternatively spliced variant to dampen resistance
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    BRPF1 bridges H3K4me3 and H3K23ac in human ESCs and is essential to pluripotency
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    SUMOylation of HNRNPA2B1 modulates RPA dynamics during unperturbed replication and genotoxic stress responses
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    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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    Human SMARCA5 is continuously required to maintain nucleosome spacing
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    The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma
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    Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy
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    Two modes of Cue2-mediated mRNA cleavage with distinct substrate recognition initiate no-go decay
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    The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation
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    POU1F1/Pou1f1 c.143-83A > G variant disrupts the branch site in pre-mRNA and leads dwarfism
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    The ADP-ribose hydrolase NUDT5 is important for DNA repair
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    The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model
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    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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    Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines
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    Epidermal stratification requires retromer-mediated desmoglein-1 recycling
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    PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing
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    Mitochondrial cristae architecture protects against mtDNA release and inflammation
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    Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics
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    IFT-A structure reveals carriages for membrane protein transport into cilia
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    Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice
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    Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice
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    Mcm2 promotes stem cell differentiation via its ability to bind H3-H4
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    The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2
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    Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression
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    Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq
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    Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells
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    Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication
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    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
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    Purification of exosome-enriched proteins produced in a Drosophila cell line by size exclusion chromatography
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    CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors
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    LncRNA CCTT-mediated RNA-DNA and RNA-protein interactions facilitate the recruitment of CENP-C to centromeric DNA during kinetochore assembly
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    V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
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    Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
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  195. Oct 2022
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    Structure and functionality of a multimeric human COQ7:COQ9 complex
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    Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity
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    METTL3 regulates m6A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma
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    A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation
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    Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer
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    Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas
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    RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA
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    Allelic variation in the Arabidopsis TNL CHS3/CSA1 immune receptor pair reveals two functional cell-death regulatory modes
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