831 Matching Annotations
  1. Oct 2022
  2. journals.sagepub.com journals.sagepub.com
    Acute Manganese Exposure Modifies the Translation Machinery via PI3K/Akt Signaling in Glial Cells
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    journals.sagepub.com/doi/full/10.1177/17590914221131452
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    E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance
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    sciencedirect.com/science/article/pii/S2211124722012773
  4. Sep 2022
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP
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    ncbi.nlm.nih.gov/pmc/articles/PMC9506296/
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    Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor
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    sciencedirect.com/science/article/pii/S2211124722011950
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opioids Cause Sex-Specific Vascular Changes via Cofilin-Extracellular Signal-Regulated Kinase Signaling: Female Mice Present Higher Risk of Developing Morphine-Induced Vascular Dysfunction than Male Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8612963/
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    Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
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    nature.com/articles/s42003-022-03942-4
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep
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    ncbi.nlm.nih.gov/pmc/articles/PMC9452821/
  10. www.sciencedirect.com www.sciencedirect.com
    Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis
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    sciencedirect.com/science/article/pii/S2211124722011378
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na/K-ATPase Suppresses LPS-Induced Pro-Inflammatory Signaling Through Lyn
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    ncbi.nlm.nih.gov/pmc/articles/PMC9442361/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8904293/
  13. Aug 2022
  14. www.sciencedirect.com www.sciencedirect.com
    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
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    sciencedirect.com/science/article/pii/S1550413122003485
  15. www.science.org www.science.org
    Functional and biological heterogeneity of KRASQ61 mutations
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    science.org/doi/10.1126/scisignal.abn2694
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    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
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    sciencedirect.com/science/article/pii/S1097276522007109
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    Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
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    sciencedirect.com/science/article/pii/S2211124722010257
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    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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    sciencedirect.com/science/article/pii/S2211124722009949
  19. Jul 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610822002756
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    Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
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    sciencedirect.com/science/article/pii/S2211124722008713
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    Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover
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    sciencedirect.com/science/article/pii/S1534580722004518
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide expression and methylation analyses reveal aberrant cell adhesion signaling in tyrosine kinase inhibitor-resistant CML cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9245083/
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    The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis
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    sciencedirect.com/science/article/pii/S1097276522005445
  25. Jun 2022
  26. 52.53.155.43 52.53.155.43
    mcr-21-0994-html.html
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  27. 52.53.155.43 52.53.155.43
    ajpendo.00293.2021-html.html
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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9152158/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Undercarboxylated, but not Carboxylated, Osteocalcin suppresses TNF-α induced inflammatory signaling pathway in Myoblast
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    ncbi.nlm.nih.gov/pmc/articles/PMC9188654/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Requirement of hippocampal DG nNOS-CAPON dissociation for the anxiolytic and antidepressant effects of fluoxetine
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    ncbi.nlm.nih.gov/pmc/articles/PMC9131266/
  31. www.sciencedirect.com www.sciencedirect.com
    Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses
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    sciencedirect.com/science/article/pii/S2211124722006763
  32. May 2022
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23099
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9020775/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational Strategies for Repotrectinib in Neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8571000/
  36. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  37. Apr 2022
  38. www.science.org www.science.org
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    science.org/doi/full/10.1126/sciadv.abm9987
  39. academic.oup.com academic.oup.com
    GH action in prostate cancer cells promotes proliferation limits apoptosis and regulates cancer-related gene expression
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    academic.oup.com/endo/article/163/5/bqac031/6564019
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    Tissue remodeling by an opportunistic pathogen triggers allergic inflammation
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    sciencedirect.com/science/article/pii/S1074761322001728
  41. www.sciencedirect.com www.sciencedirect.com
    Enhanced safety and efficacy of protease-regulated CAR-T cell receptors
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    sciencedirect.com/science/article/pii/S0092867422003919
  42. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Copper bis(thiosemicarbazone) complexes modulate P-glycoprotein expression and function in human brain microvascular endothelial cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15609
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    Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice
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    sciencedirect.com/science/article/pii/S2666379122001148
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    Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury
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    sciencedirect.com/science/article/pii/S0896627322002574
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    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
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    sciencedirect.com/science/article/pii/S1097276522002647
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    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
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    sciencedirect.com/science/article/pii/S221112472200393X
  47. www.sciencedirect.com www.sciencedirect.com
    Melanomas with concurrent BRAF non-p.V600 and NF1 loss-of-function mutations are targetable by BRAF/MEK inhibitor combination therapy
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    sciencedirect.com/science/article/pii/S2211124722003862
  48. www.sciencedirect.com www.sciencedirect.com
    Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
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    sciencedirect.com/science/article/pii/S2211124722003722
  49. www.jneurosci.org www.jneurosci.org
    ADAM17 regulates p75NTR–mediated fibrinolysis and nerve remyelination
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    jneurosci.org/content/42/12/2433
  50. aacrjournals.org aacrjournals.org
    δ-Tocotrienol is the most potent vitamin E form in inhibiting prostate cancer cell growth and inhibits prostate carcinogenesis in Ptenp-/- mice
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    aacrjournals.org/cancerpreventionresearch/article/15/4/233/682296/Tocotrienol-is-the-Most-Potent-Vitamin-E-Form-in
  51. Mar 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Pathogen size alters C-type lectin receptor signaling in dendritic cells to influence CD4 Th9 cell differentiation
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    sciencedirect.com/science/article/pii/S2211124722003114
  53. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
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    sciencedirect.com/science/article/pii/S2211124722002583
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Crosstalk between ERK and MRTF-A signaling regulates TGFβ1-induced epithelial-mesenchymal transition
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    onlinelibrary.wiley.com/doi/10.1002/jcp.30705
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peripheral nerve fibroblasts secrete neurotrophic factors to promote axon growth of motoneurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC8820717/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
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    ncbi.nlm.nih.gov/pmc/articles/PMC8860447/
  57. elifesciences.org elifesciences.org
    A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx
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    elifesciences.org/articles/72849
  58. www.sciencedirect.com www.sciencedirect.com
    Creatine transport and creatine kinase activity is required for CD8+ T cell immunity
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    sciencedirect.com/science/article/pii/S2211124722001735
  59. www.sciencedirect.com www.sciencedirect.com
    Diacylglycerol kinase η regulates cell proliferation and its levels are elevated by glucocorticoids in undifferentiated neuroblastoma cells
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    sciencedirect.com/science/article/pii/S0006291X22003059
  60. Feb 2022
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8807877/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pigment Epithelium Derived Factor Is Involved in the Late Phase of Osteosarcoma Metastasis by Increasing Extravasation and Cell-Cell Adhesion
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    ncbi.nlm.nih.gov/pmc/articles/PMC8842676/
  63. www.sciencedirect.com www.sciencedirect.com
    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
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    sciencedirect.com/science/article/pii/S221112472200033X
  64. www.nature.com www.nature.com
    Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo
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    nature.com/articles/s41375-020-01077-1
  65. Jan 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Acetylation-dependent regulation of BRAF oncogenic function
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    sciencedirect.com/science/article/pii/S2211124721017629
  67. elifesciences.org elifesciences.org
    Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice
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    elifesciences.org/articles/72937
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transgenic overexpression of CTRP3 does not prevent alcohol induced hepatic steatosis in female mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8740976/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua
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    ncbi.nlm.nih.gov/pmc/articles/PMC8700290/
  70. Dec 2021
  71. www.sciencedirect.com www.sciencedirect.com
    RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth
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    sciencedirect.com/science/article/pii/S2589004221015868
  72. www.sciencedirect.com www.sciencedirect.com
    The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
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    sciencedirect.com/science/article/pii/S1534580721009941
  73. www.sciencedirect.com www.sciencedirect.com
    APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain
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    sciencedirect.com/science/article/pii/S1097276521010339
  74. elifesciences.org elifesciences.org
    Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology
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    elifesciences.org/articles/73430
  75. www.sciencedirect.com www.sciencedirect.com
    GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway
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    sciencedirect.com/science/article/pii/S2589004221014887
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8172524/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic and experimental evidence that ALKATI does not predict single agent sensitivity to ALK inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8603052/
  78. reader.elsevier.com reader.elsevier.com
    Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
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    reader.elsevier.com/reader/sd/pii/S2211124721015497
  79. www.sciencedirect.com www.sciencedirect.com
    CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
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    sciencedirect.com/science/article/pii/S2211124721015461
  80. Nov 2021
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts
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    ncbi.nlm.nih.gov/pmc/articles/PMC8608148/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly
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    ncbi.nlm.nih.gov/pmc/articles/PMC8598234/
  83. www.sciencedirect.com www.sciencedirect.com
    Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
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    sciencedirect.com/science/article/pii/S2211124721015400
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8567381/
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    Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration
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    sciencedirect.com/science/article/pii/S2589004221012311
  86. link.springer.com link.springer.com
    TGF-β orchestrates the phenotype and function of monocytic myeloid-derived suppressor cells in colorectal cancer
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    link.springer.com/article/10.1007/s00262-021-03081-5
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    LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
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    sciencedirect.com/science/article/pii/S2666634021003421
  88. Oct 2021
  89. www.sciencedirect.com www.sciencedirect.com
    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
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    sciencedirect.com/science/article/pii/S2589004221011925
  90. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Early resistance training-mediated stimulation of daily muscle protein synthetic responses to higher habitual protein intake in middle-aged adults
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP281907
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    Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation
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    sciencedirect.com/science/article/pii/S1074761321004039
  92. www.embopress.org www.embopress.org
    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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    embopress.org/doi/full/10.15252/embr.202052254
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    c-FOS drives reversible basal to squamous cell carcinoma transition
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    sciencedirect.com/science/article/pii/S2211124721012286
  94. Sep 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study
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    ncbi.nlm.nih.gov/pmc/articles/PMC8435395/
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    Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity
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    sciencedirect.com/science/article/pii/S1550413121004228
  97. www.sciencedirect.com www.sciencedirect.com
    Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors
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    sciencedirect.com/science/article/pii/S1097276521007413
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    RARG variant predictive of doxorubicin-induced cardiotoxicity identifies a cardioprotective therapy
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    sciencedirect.com/science/article/pii/S193459092100343X
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC8384845/
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    UV-induced reduction in Polycomb repression promotes epidermal pigmentation
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    sciencedirect.com/science/article/pii/S1534580721006365
  101. Aug 2021
  102. www.sciencedirect.com www.sciencedirect.com
    Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors
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