616 Matching Annotations
  1. Mar 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10924942/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of β-catenin stability
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10896346/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10920892/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Estrogen Receptor Dimerization BRET-Based Biosensors for Screening Estrogenic Endocrine-Disrupting Chemicals
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10923609/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10924943/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527600/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    scAbsolute: measuring single-cell ploidy and replication status
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    ncbi.nlm.nih.gov/pmc/articles/PMC10910719/
  9. www.sciencedirect.com www.sciencedirect.com
    Effectiveness of chemical inactivation of infectious liquid biological waste: a randomized sample study of research laboratories in Switzerland
    3
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    sciencedirect.com/science/article/pii/S2588933824000049
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination
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    ncbi.nlm.nih.gov/pmc/articles/PMC10897158/
  11. Feb 2024
  12. www.sciencedirect.com www.sciencedirect.com
    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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    sciencedirect.com/science/article/pii/S1097276524000984
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    The proteomic landscape of genotoxic stress-induced micronuclei
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    sciencedirect.com/science/article/pii/S1097276524000972
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for antibody recognition of the proximal MUC16 ectodomain
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875768/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenomic analyses identify FOXM1 as a key regulator of anti-tumor immune response in esophageal adenocarcinoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10876663/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Production of infectious reporter murine norovirus by VP2 trans-complementation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878090/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878271/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879184/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering an Autonucleolytic Mammalian Suspension Host Cell Line to Reduce DNA Impurity Levels in Serum-Free Lentiviral Process Streams
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10877604/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10881528/
  21. link.springer.com link.springer.com
    Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins
    1
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    link.springer.com/article/10.1038/s41598-024-54705-6
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined therapy of CAR-IL-15/IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor effect against gastric cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10874561/
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    Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment
    2
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    sciencedirect.com/science/article/pii/S2211124724001256
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10864035/
  25. www.biorxiv.org www.biorxiv.org
    PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma
    1
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    biorxiv.org/content/10.1101/2023.12.23.573190v1
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10857481/
  27. cancerci.biomedcentral.com cancerci.biomedcentral.com
    NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route
    1
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    cancerci.biomedcentral.com/articles/10.1186/s12935-024-03249-w
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    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
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    sciencedirect.com/science/article/pii/S240547122400022X
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actin-dependent recruitment of AGO2 to the zonula adherens
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    ncbi.nlm.nih.gov/pmc/articles/PMC10848941/
  30. journals.plos.org journals.plos.org
    CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly
    1
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    journals.plos.org/plosgenetics/article
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10782643/
  32. www.sciencedirect.com www.sciencedirect.com
    Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
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    sciencedirect.com/science/article/pii/S2211124724000779
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10823221/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3
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    ncbi.nlm.nih.gov/pmc/articles/PMC10826106/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10896723/
  36. Jan 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RBL2 represses the transcriptional activity of Multicilin to inhibit multiciliogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10803754/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICH deficiency limits the progression of MYC-induced B-cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10803365/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isolation and Characterization of Neutralizing Monoclonal Antibodies from a Large Panel of Murine Antibodies against RBD of the SARS-CoV-2 Spike Protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC10801580/
  40. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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    sciencedirect.com/science/article/pii/S1097276523010857
  41. link.springer.com link.springer.com
    Selective gene expression maintains human tRNA anticodon pools during differentiation
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    link.springer.com/article/10.1038/s41556-023-01317-3
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    PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis
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    sciencedirect.com/science/article/pii/S2211124723016558
  43. Dec 2023
  44. www.sciencedirect.com www.sciencedirect.com
    FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration
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    sciencedirect.com/science/article/pii/S2589004223025749
  45. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
    1
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    sciencedirect.com/science/article/pii/S2211124723015280
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    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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    sciencedirect.com/science/article/pii/S2589004223026731
  47. link.springer.com link.springer.com
    Rational optimization of a transcription factor activation domain inhibitor
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    link.springer.com/article/10.1038/s41594-023-01159-5
  48. Nov 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
    1
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    sciencedirect.com/science/article/pii/S2211124723014729
  50. www.sciencedirect.com www.sciencedirect.com
    An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds
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    sciencedirect.com/science/article/pii/S2090123223003612
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized peptide nanofibrils as efficient transduction enhancers for in vitro and ex vivo gene transfer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10666768/
  52. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress
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    sciencedirect.com/science/article/pii/S1368764623000985
  53. Oct 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Regulation of STING activity in DNA sensing by ISG15 modification
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    sciencedirect.com/science/article/pii/S2211124723012895
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    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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    sciencedirect.com/science/article/pii/S221112472301210X
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10591056/
  57. www.nature.com www.nature.com
    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
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    nature.com/articles/s41420-023-01639-z
  58. Sep 2023
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Insights into product and process related challenges of lentiviral vector bioprocessing
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    onlinelibrary.wiley.com/doi/10.1002/bit.28498
  60. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive accumulation of non-muscle myosin IIB during mitosis requires its translocation activity
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    sciencedirect.com/science/article/pii/S2589004223018503
  61. 52.53.155.43 52.53.155.43
    vdad120-html.html
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    52.53.155.43/6d7222f39ce6ff806d6be40a37ce30f7488ce63a/vdad120-html.html
  62. www.biorxiv.org www.biorxiv.org
    TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling
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    biorxiv.org/content/10.1101/2023.09.04.556165v1
  63. Aug 2023
  64. www.sciencedirect.com www.sciencedirect.com
    Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons
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    sciencedirect.com/science/article/pii/S2666979X23002136
  65. www.biorxiv.org www.biorxiv.org
    Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins
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    biorxiv.org/content/10.1101/2023.08.18.553740v1
  66. www.nature.com www.nature.com
    Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression
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    nature.com/articles/s41596-023-00863-2
  67. www.sciencedirect.com www.sciencedirect.com
    IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
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    sciencedirect.com/science/article/pii/S2211124723010070
  68. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
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    52.53.155.43/9f1a09025b86686c62561e67323b0c82e4153e7b/PIIS2666379123002987-html.html
  69. Jul 2023
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early protective effect of a (“pan”) coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration
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    ncbi.nlm.nih.gov/pmc/articles/PMC10372429/
  71. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    sciencedirect.com/science/article/pii/S0092867423006967
  72. www.sciencedirect.com www.sciencedirect.com
    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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    sciencedirect.com/science/article/pii/S1534580723003313
  73. 52.53.155.43 52.53.155.43
    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    52.53.155.43/bc0eed2683790c341dcd40acf534b132d1de8ed2/2023.05.10.540298.full-html.html
  74. pubs.acs.org pubs.acs.org
    SIRIUS, Ultra-Scintillating Upconversion Breast Implant for Remote Orthotopic Photodynamic Therapy
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    pubs.acs.org/doi/10.1021/acsnano.3c01916
  75. 52.53.155.43 52.53.155.43
    cir-22-0815-html.html
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    52.53.155.43/0c7b493d1804c631a7718bd69d23acbb033c9efb/cir-22-0815-html.html
  76. Jun 2023
  77. www.sciencedirect.com www.sciencedirect.com
    Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth
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    sciencedirect.com/science/article/pii/S2211124723006915
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    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    sciencedirect.com/science/article/pii/S0092867423005986
  79. www.sciencedirect.com www.sciencedirect.com
    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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    sciencedirect.com/science/article/pii/S2211124723006794
  80. www.biorxiv.org www.biorxiv.org
    Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis
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    biorxiv.org/content/10.1101/2023.06.14.544493v1
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLIT2/ROBO1 signaling suppresses mTORC1 for organelle control and bacterial killing
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    ncbi.nlm.nih.gov/pmc/articles/PMC10264968/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of the gut microbiota confers cisplatin resistance in epithelial ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9772178/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network
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    ncbi.nlm.nih.gov/pmc/articles/PMC7614333/
  85. May 2023
  86. www.embopress.org www.embopress.org
    Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG-Syt1-SV2 plasma membrane nanocluster for synaptic vesicle entry
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    embopress.org/doi/10.15252/embj.2022112095
  87. www.sciencedirect.com www.sciencedirect.com
    Actuation of single downstream nodes in growth factor network steers immune cell migration
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    sciencedirect.com/science/article/pii/S1534580723001958
  88. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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    sciencedirect.com/science/article/pii/S2211124723004953
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A rabies virus–based toolkit for efficient retrograde... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154474/
  90. www.biorxiv.org www.biorxiv.org
    L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    biorxiv.org/content/10.1101/2023.03.04.531072v1
  91. www.sciencedirect.com www.sciencedirect.com
    TOPK inhibits TNF-α-induced granulosa cell apoptosis via regulation SIRT1/p53
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    sciencedirect.com/science/article/pii/S0006291X23005508
  92. Apr 2023
  93. www.sciencedirect.com www.sciencedirect.com
    CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies
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    sciencedirect.com/science/article/pii/S2589004223005205
  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Primary Glial Cell and Glioblastoma Morphology in Cocultures Depends on Scaffold Design and Hydrogel Composition
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    onlinelibrary.wiley.com/doi/10.1002/adbi.202300029
  95. Mar 2023
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals
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    ncbi.nlm.nih.gov/pmc/articles/PMC10032658/
  97. www.sciencedirect.com www.sciencedirect.com
    Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing
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    sciencedirect.com/science/article/pii/S0092867423001708
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC9933850/
  99. Jan 2023
  100. www.sciencedirect.com www.sciencedirect.com
    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
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  212. Mar 2021
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  216. Feb 2021
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  226. Dec 2020
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