1,759 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimized reporters for multiplexed detection of transcription factor activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11667439/
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    sciencedirect.com/science/article/pii/S0092867424013266
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    GABAA receptor π forms channels that stimulate ERK through a G-protein-dependent pathway
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    sciencedirect.com/science/article/pii/S1097276524009213
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    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    sciencedirect.com/science/article/pii/S1097276524009146
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    p53 induces circFRMD4A to suppress cancer development through glycolytic reprogramming and cuproptosis
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    sciencedirect.com/science/article/pii/S1097276524009183
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    Multiple pathways to red carotenoid coloration: House finches (Haemorhous mexicanus) do not use CYP2J19 to produce red plumage
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    biorxiv.org/content/10.1101/2024.11.26.625526v1
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    Identification of Antisense RNA NRAS-AS and Its Preliminary Exploration of the Anticancer Regulatory Mechanism
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    mdpi.com/2073-4425/15/12/1524
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    m6A sites in the coding region trigger translation-dependent mRNA decay
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    Activity-dependent COX-2 proteolysis modulates aerobic respiration and proliferation in a prostaglandin-independent manner
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    sciencedirect.com/science/article/pii/S2589004224026282
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    lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing
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  12. Nov 2024
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    The role of the tricellular junction protein ILDR2 in glomerulopathies: Expression patterns and functional insights
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    A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice
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    ESR1 fusion proteins invoke breast cancer subtype-dependent enrichment of ligand independent pro-oncogenic signatures and phenotypes
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    biorxiv.org/content/10.1101/2023.09.18.558175v1
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    Stress disrupts engram ensembles in lateral amygdala to generalize threat memory in mice
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    A platform of functional studies of ESCC-associated gene mutations identifies the roles of TGFBR2 in ESCC progression and metastasis
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    sciencedirect.com/science/article/pii/S2211124724013032
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    Visualization of endogenous G proteins on endosomes and other organelles
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    Targeting IL-1/IRAK1/4 signaling in Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse
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    Synthesis and Pharmacological Characterization of Fluorescent Ligands Targeting the Angiotensin II Receptors Derived from Agonists, β-Arrestin-Biased Agonists, and Antagonists
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    Potassium ion channel modulation at cancer-neural interface enhances neuronal excitability in epileptogenic glioblastoma multiforme
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    Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27
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    The Influence of Physical Training on Breast Cancer: The Role of Exercise-Induced Myokines in Regulating Breast Cancer Cell Growth and Survival
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    Functional implications of the exon 9 splice insert in GluK1 kainate receptors
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    physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP286665
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    Conservation of the cooling agent binding pocket within the TRPM subfamily
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    Thymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacy
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    Functional Relationships between L1CAM, LC3, ATG12, and Aβ
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    Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development
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  32. Oct 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Purkinje cell hyperexcitability and depressive-like behavior in mice lacking erg3 (ether-à-go-go–related gene) K+ channel subunits
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    Legumain is a paracrine regulator of osteoblast differentiation and mediates the inhibitory effect of TGF-β1 on osteoblast maturation
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    CALHM2 is a mitochondrial protein import channel that regulates fatty acid metabolism
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    Dual regulation of IP3 receptors by IP3 and PIP2 controls the transition from local to global Ca2+ signals
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    Oncogenic cells of renal embryonic lineage sensitive to the small molecule inhibitor QC6352 display depletion of KDM4 levels and disruption of ribosome biogenesis
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    Long noncoding RNA Gm4419 promotes mesangial cell proliferation and extracellular matrix accumulation via the miR-455-3p/histone deacetylase 2 axis
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    CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny
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    Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke
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  41. Sep 2024
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGF12 Positively Regulates Keratinocyte Proliferation by Stabilizing MDM2 and Inhibiting p53 Activity in Psoriasis
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    CT45A1-mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell-in-cell structure, potentiating the progression of microsatellite instability-high colorectal cancer
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    A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia
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    Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen
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    Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping
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    Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer
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    MC4R Variants Modulate α-MSH and Setmelanotide Induced Cellular Signaling at Multiple Levels
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    Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition
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    Targeted degradation of specific TEAD paralogs by small molecule degraders
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    ZG16 enhances the maturation of dendritic cells via induction of CD40 and contributes to the antitumor immunity in pancreatic cancer
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    ESR1 Fusions Invoke Breast Cancer Subtype-Dependent Enrichment of Ligand-Independent Oncogenic Signatures and Phenotypes
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    Epigenetic alterations in bioaccumulators of cadmium: Lessons from mammalian kidneys and plants
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    Proteome-scale characterisation of motif-based interactome rewiring by disease mutations
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    Anti-HDGF antibody targets EGFR tyrosine kinase inhibitor-tolerant cells in NSCLC patient-derived xenografts
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    Smarcd1 subunit of SWI/SNF chromatin-remodeling complexes collaborates with E2a to promote murine lymphoid specification
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    SRSF3 suppresses RCC tumorigenesis and progression via regulating SP4 alternative splicing
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  68. Aug 2024
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calibrated ribosome profiling assesses the dynamics of ribosomal flux on transcripts
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    Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping
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    Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain Metastases
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    Rhythms in lipid droplet content driven by a metabolic oscillator are conserved throughout evolution
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    Defective CFTR modulates mechanosensitive channels TRPV4 and PIEZO1 and drives endothelial barrier failure
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    Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
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    A proteome-wide quantitative platform for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs
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    Satellite cell-derived TRIM28 is pivotal for mechanical load- and injury-induced myogenesis
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    Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway
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    A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis
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    Satellite cell-derived TRIM28 is pivotal for mechanical load- and injury-induced myogenesis | EMBO reports
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    SIRT1 improves lactate homeostasis in the brain to alleviate parkinsonism via deacetylation and inhibition of PKM2
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    Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
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    SARS-CoV-2 Rapidly Infects Peripheral Sensory and Autonomic Neurons, Contributing to Central Nervous System Neuroinvasion before Viremia
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    Subcellular Redox Responses Reveal Different Cu-dependent Antioxidant Defenses between Mitochondria and Cytosol
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    Stimulating VAPB-PTPIP51 ER-mitochondria tethering corrects FTD/ALS mutant TDP43 linked Ca2+ and synaptic defects
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    Adeno-Associated Vector-Delivered CRISPR/SaCas9 System Reduces Feline Leukemia Virus Production In Vitro
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