6,200 Matching Annotations
  1. Jun 2026
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    Comprehensive mapping of the virus and host factors that guide the paths of HIV-1 escape from a therapeutic
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    sciencedirect.com/science/article/pii/S2211124726006364
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    UBE2O Drives Immune Evasion and Radioimmunotherapy Resistance in Lung Cancer by Degrading CDKL1 to Induce PD-L1 Transcription
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76223
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    NSUN2-mediated m5C modification of BHLF1 RNA facilitates the lytic replication of Epstein-Barr virus
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    sciencedirect.com/science/article/pii/S2211124726006406
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    A practical alternative to live cell-based assay for AQP4 and MOG antibody detection
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    sciencedirect.com/science/article/pii/S2352396426002215
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    An optimized RNA polymerase II minigenome system for Nipah virus
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    biorxiv.org/content/10.64898/2026.06.12.731861v1
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    The activity of EGFR CAR-NK and CAR-T cells against EGFR inhibitor-resistant NSCLC and drug-tolerant persister cells
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    aacrjournals.org/clincancerres/article/31/22/4745/767041/The-Activity-of-EGFR-CAR-NK-and-CAR-T-Cells
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    Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked release
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    pmc.ncbi.nlm.nih.gov/articles/PMC13275065/
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    B7 homolog 3-targeted CAR-T cells secreting EGFR T-cell engagers for improved control of glioblastoma progression
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    link.springer.com/article/10.1186/s43556-026-00492-7
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    Engineered T cell membrane coated nanoparticles reverse thermo-resistance and reprogram tumor microenvironment to synergistically potentiate bladder cancer photothermal immunotherapy
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    TMPRSS2-ERG confers resistance of prostate cancer to antiandrogens
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    Unveiling ER-Phagy Receptors in Thyroid Cancer: A Combined Approach of Public Data Mining and In Vitro Validation
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    Development of CAR T cells Targeting a Surface RNA Binding Protein for the Treatment of Acute Leukemias
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    Armored chimeric antigen receptor T-cell therapy targets antigen-heterogeneous glioma
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    VMP1 forms a Ca2+ release channel essential for postnatal heartbeat
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    Structurally exclusive Teneurin complexes orchestrate divergent programs in early cortical development
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    Functional genomic analysis reveals HAVCR1 as the key regulator of 5q33.3 locus linked to hyperlipidemia
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    HSD3B1 links ileal steroid metabolism to bile acid regulation in patients with prostate cancer
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    Hirsutine Ameliorates High-Fat Diet-Induced Cardiomyopathy Through Promoting LRPPRC-Regulated Mitophagy via the PINK1/Parkin Axis in Mice
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    FANCA-dependent FEN1 recruitment suppresses transcription-replication conflicts and PARPi sensitivity
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    Sphingosine-1-Phosphate Receptor 1 Regulates Competition Dependent Astrocyte Morphogenesis and Tiling in Murine Cortex
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    onlinelibrary.wiley.com/doi/10.1002/glia.70177
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    Nuclear CK1δ as a critical determinant of PER:CRY complex dynamics and circadian period
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    A malignant subpopulation of H2AFZ+ cells interacts with myeloid cells to promote an anti-inflammatory microenvironment and drive hepatic metastasis, revealing an immunotherapeutic strategy for pancreatic ductal adenocarcinoma
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    Targeted KRASG12V Degradation in vivo Elicits Lung Adenocarcinoma Regression with Subsequent Relapse from Dysregulated Proteolysis
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    A Non-canonical RNA-Binding Function of NQO1 Drives Angiogenesis in Esophageal Squamous Cell Carcinoma via Extracellular Vesicle-Mediated AGRN Transfer
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    Lactylation Converts ABHD6 into a Mitochondrial Regulator That Drives Lenvatinib Resistance in Hepatocellular Carcinoma
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    DPY30 is an epigenetic decoupler linking replication stress to immunoediting in pancreatic cancer
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    DGAT1 Inhibition Induces Ferroptosis and Enhances Cancer Immunotherapy Efficacy
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    ZNF512B safeguards genome integrity at regulatory regions to repress the SASP and inflammation
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    sciencedirect.com/science/article/pii/S1934590926002018
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    Development of a Brain‐Penetrant Nurr1 Agonist Tool
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    Three New HHDP-Bridged Macrocyclic Polyphenols With FXR Agonistic Activity From Penthorum chinense Pursh
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    p300 Degradation by the p53-SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity
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    m6A-Mediated Glycolysis by IL-37 Drives T Cell Metabolic Reprogramming to Regulate Colitis
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    Ultrasound-Actuated Gene Editing in Human Kidney Organoids
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    Selenoprotein S plays role in translation and membrane protein biogenesis
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    biorxiv.org/content/10.64898/2026.06.08.725543v1
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    Combinatorial docking and molecular generation to navigate over 100-billion molecules for prospective ligand discovery
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    VMP1 forms a Ca2+ release channel essential for postnatal heartbeat
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    CPSF2-mediated 3’ UTR truncation of MTERF3 drives mitochondrial dysfunction and osteosarcoma progression
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    G4 DNA potentiates KDM2B phase separation to couple transcriptional repression with immune remodeling in hepatocellular carcinoma
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    RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription
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    MYCN drives pediatric glioma transformation from neural progenitors and creates distinct therapeutic vulnerabilities
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    STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation
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    BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
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    HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
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    MCCC2 stabilizes LTBP1 via suppressing SMURF1-dependent ubiquitination to drive bone metastasis in prostate cancer
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    Peptide-MHC-targeted engineered virus-like particles enable selective priming and gene editing of tumor-specific T cells
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    Epigenetic control of microglial mitochondrial immunity by KAT7 drives Alzheimer’s disease pathogenesis
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    The MLLT3 YEATS domain binds histone marks (H3K9/18/27ac/cr) and ncRNA (7SK), linking transcription and RNA signaling to regulate hematopoiesis
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    Astrocyte-derived PTPRZ1 regulates excitatory synapse density in the mouse cortex
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    Alternatively spliced STIM2.3 is an evolutionarily late store-operated Ca2+ entry regulator expressed in brain
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    IL-6 Supports Development of an Immunosuppressive Microenvironment and Resistance to Therapy in Glioblastoma
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    Tumor cells metabolically resist immune-checkpoint therapy by macrophage efferocytosis-mediated fatty acid recycling
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    Molecular basis for the dopamine reuptake and inhibition mechanism of human dopamine transporter
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    Regulation of the endoplasmic reticulum stress sensor ATF6α through multiple oxidoreductases in the ER
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    The hepatitis E virus capsid protein forms amyloid-like fibrils that sequester TANK-binding kinase 1 to dampen antiviral responses
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    The C-terminal region of TENT5 proteins drives ER-associated mRNA polyadenylation via FNDC3 interaction
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    CFP1 promotes B cell class switch recombination through the regulation of S region germline transcription and proliferation
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    Epithelial cell expansion drives cyst progression in genetic models of autosomal recessive polycystic kidney disease
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    GPC6 facilitates progression of SHH-subgroup medulloblastoma by enhancing Hedgehog secretion and signaling responses
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    Characterization and therapeutic suppression of KEAP1-NRF2-driven resistance to KRAS inhibitors in pancreatic and lung cancer
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    The Histone Modifier KANSL2 Is an Actionable Biomarker in Multiple Myeloma
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    PI3K Regulates Wild-type RAS Signaling to Confer Resistance to KRAS Inhibition
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    A CRISPR activation screen identifies CH25H as a restriction factor against influenza viruses by targeting accessible cholesterol
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    DDR1 Promotes Immune Evasion in Colorectal Cancer by Orchestrating IL33-Mediated M2-like Polarization of Tumor-Associated Macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC13227095/
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    FET Fusion Oncoproteins Disrupt Physiologic DNA Repair and Create a Targetable Opportunity for ATR Inhibitor Therapy
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    Structure-guided optimization of SLC1A1/EAAT3-selective inhibitors targeting renal cancer metabolism
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    Tissue-selective COPII modulator SEC16B aggravates cardiovascular disease by promoting lipid export
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    Salmonella vector creates de novo parvovirus that reduces solid tumors and forms antitumor immune memory
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    Autoinhibition of the mechanosensitive lipid scramblase TMEM63B by its C-terminal tail
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    The molecular architecture of tunneling nanotubes
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    biorxiv.org/content/10.64898/2026.05.27.728322v1
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    Deacetylated PCBP1 licenses PARP1 activity for DNA damage repair
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    Optogenetic control of plasma membrane O-GlcNAcylation regulates WNK1 condensates and cellular signaling
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    LKB1 inactivation elicits an NNMT-mediated methyl sink and confers dependence on PRMT5 in lung cancer
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    NAT10-dependent N4-acetylcytidine reprograms R-loops and promotes cancer stem cell growth
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    Single-granule profiling reveals that RNP granule pH marks cellular translation
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    Canonical microRNA loss drives tumor development implicating therapeutic efficacy of enoxacin in angiosarcoma
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    CBLC-mediated ubiquitination stabilizes METTL1, enhances N7-methylguanosine modification of ESRRA, and promotes the progression of endometrial cancer
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    Characterization of a transmembrane-activating STING agonist using genetically humanized mice
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    NF1 loss in estrogen receptor-positive breast cancer induces osteoclast formation and immunosuppression to promote bone metastasis
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    Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
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    Mutant-Initiated Structure-Guided Refinement Enables Second-Generation Compact IscB Genome Editors
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.70392
  85. May 2026
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    Hsp70 is phosphorylated in a conserved response to DNA damage and contributes to cell cycle control
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