851 Matching Annotations
  1. Apr 2024
  2. www.biorxiv.org www.biorxiv.org
    Neural ensembles that encode affective mechanical and heat pain in mouse spinal cord
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    biorxiv.org/content/10.1101/2024.02.05.578816v1
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    Absence of the Klotho Function Causes Cornea Degeneration with Specific Features Resembling Fuchs Endothelial Corneal Dystrophy and Bullous Keratopathy
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    mdpi.com/2079-7737/13/3/133
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    Dendritic mGluR2 and perisomatic Kv3 signaling regulate dendritic computation of mouse starburst amacrine cells
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    nature.com/articles/s41467-024-46234-7
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    Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner
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    biorxiv.org/content/10.1101/2024.02.27.582278v1
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    Genetic determinants of blood pressure and heart rate identified through ENU-induced mutagenesis with automated meiotic mapping
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    science.org/doi/10.1126/sciadv.adj9797
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    The Updated Mouse Universal Genotyping Array Bioinformatic Pipeline Improves Genetic QC in Laboratory Mice
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    biorxiv.org/content/10.1101/2024.02.29.582794v1
  8. Mar 2024
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activation of the IKK2-NF𝜅B pathway in VSMCs inhibits calcified vascular stiffness in CKD
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    pmc.ncbi.nlm.nih.gov/articles/PMC11128211/
  10. www.biorxiv.org www.biorxiv.org
    Nucleobindin-1 (Nucb1) disruption affects feeding, metabolism, and glucose homeostasis in mice in an age-, sex-, diet- and light cycle-dependent manner
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    biorxiv.org/content/10.1101/2024.03.07.584005v2
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    piRNA loading triggers MIWI translocation from the intermitochondrial cement to chromatoid body during mouse spermatogenesis
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    nature.com/articles/s41467-024-46664-3
  12. content.iospress.com content.iospress.com
    Early Mitochondrial Defects in the 5xFAD Mouse Model of Alzheimer’s Disease
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad220884
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    Suppression of Drug Resistance in Dengue Virus
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    ncbi.nlm.nih.gov/pmc/articles/PMC4701834/
  14. Jan 2024
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact
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    pmc.ncbi.nlm.nih.gov/articles/PMC10827057/
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    Endosteal stem cells at the bone-blood interface: A double-edged sword for rapid bone formation
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    onlinelibrary.wiley.com/doi/full/10.1002/bies.202300173
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Direct interrogation of context-dependent GPCR activity with a universal biosensor platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC10802303/
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    Liver cancer initiation is dependent on metabolic zonation but decoupled from premalignant clonal expansion
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    biorxiv.org/content/10.1101/2024.01.10.575013v1
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    Anatomy, physiological features, genetics and genetic alterations, breeding and strain differences relevant to the choice of the model—Impact of 3Rs
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    sciencedirect.com/science/article/pii/B978012821180900009X
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    Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responses
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    sciencedirect.com/science/article/pii/S2211124722001607
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    Abstracts of the 18th Transgenic Technology Meeting (TT2023)
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    link.springer.com/article/10.1007/s11248-023-00372-8
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    The contribution of maternal oral, vaginal, and gut microbiota to the developing offspring gut
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    nature.com/articles/s41598-023-40703-7
  23. www.jci.org www.jci.org
    A TRPV4-dependent neuro-immune axis in the spinal cord promotes neuropathic pain
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    jci.org/articles/view/161507
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effects of reversible SERCA inhibition on catecholamine exocytosis and intracellular [Ca2+] signaling in chromaffin cells from normotensive Wistar Kyoto rats and spontaneously hypertensive rats
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    pmc.ncbi.nlm.nih.gov/articles/PMC10758371/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic influences on motor learning and superperformance mutants revealed by random mutational survey of mouse locomotion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10327015/
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    Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity
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    nature.com/articles/s42003-023-04974-0
  27. www.jci.org www.jci.org
    Hypertriglyceridemia in <i>Apoa5<sup>–/–</sup></i> mice results from reduced amounts of lipoprotein lipase in the capillary lumen
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    jci.org/articles/view/172600
  28. www.mdpi.com www.mdpi.com
    Sexual Dimorphism of the Mouse Plasma Metabolome Is Associated with Phenotypes of 30 Gene Knockout Lines
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    mdpi.com/2218-1989/13/8/947
  29. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Genotyping Protocols for Genetically Engineered Mice
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    currentprotocols.onlinelibrary.wiley.com/doi/full/10.1002/cpz1.929
  30. journals.plos.org journals.plos.org
    GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans
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    journals.plos.org/plosgenetics/article
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cre-recombinase systems for induction of neuron-specific knockout models: a guide for biomedical researchers
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    ncbi.nlm.nih.gov/pmc/articles/PMC9396489/
  32. www.biorxiv.org www.biorxiv.org
    Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer’s Disease
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    biorxiv.org/content/10.1101/2023.04.28.538637v2
  33. www.nature.com www.nature.com
    Sphingosine-1-phosphate suppresses GLUT activity through PP2A and counteracts hyperglycemia in diabetic red blood cells
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    nature.com/articles/s41467-023-44109-x
  34. www.mdpi.com www.mdpi.com
    Fatal Epileptic Seizures in Mice Having Compromised Glutathione and Ascorbic Acid Biosynthesis
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    mdpi.com/2076-3921/12/2/448
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intranasal immunization with an RBD-hemagglutinin fusion protein harnesses preexisting immunity to enhance antigen-specific responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10688985/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Studying the Roles of the Renin–Angiotensin System in Accelerating the Disease of High-Fat-Diet-Induced Diabetic Nephropathy in a db/db and ACE2 Double-Gene-Knockout Mouse Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC10779113/
  37. www.biorxiv.org www.biorxiv.org
    Astrocyte-to-microglia communication via Sema4B-Plexin-B2 modulates injury-induced reactivity of microglia
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    biorxiv.org/content/10.1101/2023.11.07.565986v1
  38. www.biorxiv.org www.biorxiv.org
    Activation of the IKK2-NFκB pathway in VSMCs inhibits calcified vascular stiffness in CKD by reducing the secretion of calcifying extracellular vesicles
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    biorxiv.org/content/10.1101/2023.07.11.548621v1
  39. www.sciencedirect.com www.sciencedirect.com
    A precisely humanized FCRN transgenic mouse for preclinical pharmacokinetics studies
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    sciencedirect.com/science/article/pii/S0006295223000618
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    Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation
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    sciencedirect.com/science/article/pii/S1043661823002979
  41. www.nature.com www.nature.com
    Revealing concealed cardioprotection by platelet Mfsd2b-released S1P in human and murine myocardial infarction
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    nature.com/articles/s41467-023-38069-5
  42. 52.53.155.43 52.53.155.43
    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
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    52.53.155.43/93ebbe5a83b6a28b0d01edad42fa81f437079176/sciimmunol.abq2424_sm-html.html
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    Novel discovery of a lymphatic bridge connecting Schlemm's canal to limbal and conjunctival lymphatic pathway
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    sciencedirect.com/science/article/pii/S1542012423000514
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    New mouse models with hypomorphic SUMF1 variants mimic attenuated forms of multiple sulfatase deficiency
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    pmc.ncbi.nlm.nih.gov/articles/PMC10832386/
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    The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease
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    nature.com/articles/s41467-023-39769-8
  46. link.springer.com link.springer.com
    Mouse Models to Study Peroxisomal Functions and Disorders: Overview, Caveats, and Recommendations
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    link.springer.com/protocol/10.1007/978-1-0716-3048-8_34
  47. www.biorxiv.org www.biorxiv.org
    Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis
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    biorxiv.org/content/10.1101/2023.11.29.569312v1
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PGE2 potentiates Orai1-mediated calcium entry contributing to peripheral sensitization
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    pmc.ncbi.nlm.nih.gov/articles/PMC10851687/
  49. www.biorxiv.org www.biorxiv.org
    BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice
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    biorxiv.org/content/10.1101/2023.08.03.551881v1
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    Neuronal deletion of nSMase2 reduces the production of Aβ and directly protects neurons
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    sciencedirect.com/science/article/pii/S0969996123000013
  51. www.mdpi.com www.mdpi.com
    ACE2 and a Traditional Chinese Medicine Formula NRICM101 Could Alleviate the Inflammation and Pathogenic Process of Acute Lung Injury
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    mdpi.com/1648-9144/59/9/1554
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ezh2-dependent methylation in oral epithelia promotes secondary palatogenesis
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    onlinelibrary.wiley.com/doi/full/10.1002/bdr2.2216
  53. www.biorxiv.org www.biorxiv.org
    Neural circuit models for evidence accumulation through choice-selective sequences
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    biorxiv.org/content/10.1101/2023.09.01.555612v3
  54. www.biorxiv.org www.biorxiv.org
    Effect size of delayed freezing, diurnal variation, and hindgut location on the mouse fecal microbiome relative to a standardized biological variable
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    biorxiv.org/content/10.1101/2023.07.13.548851v1
  55. www.mdpi.com www.mdpi.com
    Klotho Null Mutation Indirectly Leads to Age-Related Lacrimal Gland Degeneration in Mutant Mice
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    mdpi.com/2079-7737/12/10/1328
  56. www.sciencedirect.com www.sciencedirect.com
    Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term
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    sciencedirect.com/science/article/pii/S0022282823000937
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Structural-functional properties of direct-pathway striatal neurons at early and chronic stages of dopamine denervation
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    onlinelibrary.wiley.com/doi/full/10.1111/ejn.16166
  58. www.mdpi.com www.mdpi.com
    Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse
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    mdpi.com/2218-273X/13/9/1324
  59. www.biorxiv.org www.biorxiv.org
    SRRM2 splicing factor modulates cell fate in early development
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    biorxiv.org/content/10.1101/2023.12.15.571825v1
  60. www.nature.com www.nature.com
    Topologically associating domain boundaries are required for normal genome function
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    nature.com/articles/s42003-023-04819-w
  61. link.springer.com link.springer.com
    TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models
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    link.springer.com/article/10.1007/s00401-023-02615-8
  62. www.sciencedirect.com www.sciencedirect.com
    Illuminating the druggable genome: Pathways to progress
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    sciencedirect.com/science/article/pii/S1359644623003215
  63. www.pnas.org www.pnas.org
    Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs
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    pnas.org/doi/abs/10.1073/pnas.2315282120
  64. esmed.org esmed.org
    Why Angiotensin II is a Poor Choice for Circulatory Support of Ventilated COVID-19 Patients Compared to Vasopressin
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    esmed.org/MRA/mra/article/view/6310
  65. www.biorxiv.org www.biorxiv.org
    FAM210B is dispensable for erythroid differentiation in adult mice
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    biorxiv.org/content/10.1101/2023.09.26.559581v1
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    Illuminating the understudied GPCR-ome
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    sciencedirect.com/science/article/pii/S1359644623003641
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    CCN1 expression is regulated by mechanical stimuli in tendons
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    sciencedirect.com/science/article/pii/S0006291X23004734
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    PANEL 3: Otitis media animal models, cell culture, tissue regeneration & pathophysiology
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    sciencedirect.com/science/article/pii/S0165587623003816
  69. link.springer.com link.springer.com
    Web-Based Resources to Investigate Protease Function
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    link.springer.com/protocol/10.1007/978-1-0716-3589-6_1
  70. www.mdpi.com www.mdpi.com
    Standardized Complex Gut Microbiomes Influence Fetal Growth, Food Intake, and Adult Body Weight in Outbred Mice
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    mdpi.com/2076-2607/11/2/484
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    Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapy
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    sciencedirect.com/science/article/pii/S2589958923000038
  72. Dec 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroscience of Disease: Human KCNQ5 de novo mutations underlie epilepsy and intellectual disability
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    ncbi.nlm.nih.gov/pmc/articles/PMC9236882/
  74. www.biorxiv.org www.biorxiv.org
    A conditional null allele of Dync1h1 enables targeted analyses of dynein roles in neuronal length sensing and neurological disorders
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    biorxiv.org/content/10.1101/2022.02.20.481176v1
  75. content.iospress.com content.iospress.com
    The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer’s Disease
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad210581
  76. academic.oup.com academic.oup.com
    Centralizing neurofibromatosis experimental tool knowledge with the NF Research Tools Database
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    academic.oup.com/database/article/doi/10.1093/database/baac045/6613566
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mouse mutagenesis and phenotyping to generate models of development and disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11275630/
  78. content.iospress.com content.iospress.com
    JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad215370
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic Strategies to Study T Cell Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC10803070/
  80. www.biorxiv.org www.biorxiv.org
    A HUMANIZED FCRN TRANSGENIC MOUSE FOR PRECLINICAL PHARMACOKINETICS STUDIES
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    biorxiv.org/content/10.1101/2022.10.24.513622v1
  81. www.jneurosci.org www.jneurosci.org
    T-Type Ca2+ Channels Boost Neurotransmission in Mammalian Cone Photoreceptors
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    jneurosci.org/content/42/33/6325
  82. Oct 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of WNK3 kinase signaling reduces brain damage and accelerates neurological recovery after stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC4643659/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC5381450/
  85. Jun 2023
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by Angiotensin-(1-7)
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    pmc.ncbi.nlm.nih.gov/articles/PMC10881191/
  87. May 2023
  88. www.mdpi.com www.mdpi.com
    [124I]IBETA: A New A&beta; Plaque Positron Emission Tomography Imaging Agent for Alzheimer&rsquo;s Disease
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    mdpi.com/1420-3049/27/14/4552/htm
  89. pubs.acs.org pubs.acs.org
    Novologue Therapy Requires Heat Shock Protein 70 and Thioredoxin-Interacting Protein to Improve Mitochondrial Bioenergetics and Decrease Mitophagy in Diabetic Sensory Neurons
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    pubs.acs.org/doi/10.1021/acschemneuro.1c00340
  90. ejnmmires.springeropen.com ejnmmires.springeropen.com
    [18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice
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    ejnmmires.springeropen.com/articles/10.1186/s13550-022-00914-x
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differential Responses to Sigma-1 or Sigma-2 Receptor Ablation in Adiposity, Fat Oxidation, and Sexual Dimorphism
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    pmc.ncbi.nlm.nih.gov/articles/PMC9506228/
  92. asbmr.onlinelibrary.wiley.com asbmr.onlinelibrary.wiley.com
    Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice
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    asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.4323
  93. www.embopress.org www.embopress.org
    Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium
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