835 Matching Annotations
  1. Jan 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responses
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    sciencedirect.com/science/article/pii/S2211124722001607
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    Abstracts of the 18th Transgenic Technology Meeting (TT2023)
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    link.springer.com/article/10.1007/s11248-023-00372-8
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    The contribution of maternal oral, vaginal, and gut microbiota to the developing offspring gut
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    nature.com/articles/s41598-023-40703-7
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    A TRPV4-dependent neuro-immune axis in the spinal cord promotes neuropathic pain
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    jci.org/articles/view/161507
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effects of reversible SERCA inhibition on catecholamine exocytosis and intracellular [Ca2+] signaling in chromaffin cells from normotensive Wistar Kyoto rats and spontaneously hypertensive rats
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    pmc.ncbi.nlm.nih.gov/articles/PMC10758371/
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    Genetic influences on motor learning and superperformance mutants revealed by random mutational survey of mouse locomotion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10327015/
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    Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity
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    nature.com/articles/s42003-023-04974-0
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    Hypertriglyceridemia in <i>Apoa5<sup>–/–</sup></i> mice results from reduced amounts of lipoprotein lipase in the capillary lumen
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    jci.org/articles/view/172600
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    Sexual Dimorphism of the Mouse Plasma Metabolome Is Associated with Phenotypes of 30 Gene Knockout Lines
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    mdpi.com/2218-1989/13/8/947
  11. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Genotyping Protocols for Genetically Engineered Mice
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    currentprotocols.onlinelibrary.wiley.com/doi/full/10.1002/cpz1.929
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    GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans
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    journals.plos.org/plosgenetics/article
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    Cre-recombinase systems for induction of neuron-specific knockout models: a guide for biomedical researchers
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    ncbi.nlm.nih.gov/pmc/articles/PMC9396489/
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    Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer’s Disease
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    biorxiv.org/content/10.1101/2023.04.28.538637v2
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    Sphingosine-1-phosphate suppresses GLUT activity through PP2A and counteracts hyperglycemia in diabetic red blood cells
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    nature.com/articles/s41467-023-44109-x
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    Fatal Epileptic Seizures in Mice Having Compromised Glutathione and Ascorbic Acid Biosynthesis
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    mdpi.com/2076-3921/12/2/448
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intranasal immunization with an RBD-hemagglutinin fusion protein harnesses preexisting immunity to enhance antigen-specific responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10688985/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Studying the Roles of the Renin–Angiotensin System in Accelerating the Disease of High-Fat-Diet-Induced Diabetic Nephropathy in a db/db and ACE2 Double-Gene-Knockout Mouse Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC10779113/
  19. www.biorxiv.org www.biorxiv.org
    Astrocyte-to-microglia communication via Sema4B-Plexin-B2 modulates injury-induced reactivity of microglia
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    biorxiv.org/content/10.1101/2023.11.07.565986v1
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    Activation of the IKK2-NFκB pathway in VSMCs inhibits calcified vascular stiffness in CKD by reducing the secretion of calcifying extracellular vesicles
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    biorxiv.org/content/10.1101/2023.07.11.548621v1
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    A precisely humanized FCRN transgenic mouse for preclinical pharmacokinetics studies
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    sciencedirect.com/science/article/pii/S0006295223000618
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    Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation
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    sciencedirect.com/science/article/pii/S1043661823002979
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    Revealing concealed cardioprotection by platelet Mfsd2b-released S1P in human and murine myocardial infarction
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    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
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    Novel discovery of a lymphatic bridge connecting Schlemm's canal to limbal and conjunctival lymphatic pathway
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    sciencedirect.com/science/article/pii/S1542012423000514
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    New mouse models with hypomorphic SUMF1 variants mimic attenuated forms of multiple sulfatase deficiency
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    The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease
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    Mouse Models to Study Peroxisomal Functions and Disorders: Overview, Caveats, and Recommendations
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    link.springer.com/protocol/10.1007/978-1-0716-3048-8_34
  29. www.biorxiv.org www.biorxiv.org
    Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis
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    biorxiv.org/content/10.1101/2023.11.29.569312v1
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PGE2 potentiates Orai1-mediated calcium entry contributing to peripheral sensitization
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    pmc.ncbi.nlm.nih.gov/articles/PMC10851687/
  31. www.biorxiv.org www.biorxiv.org
    BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice
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    Neuronal deletion of nSMase2 reduces the production of Aβ and directly protects neurons
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    sciencedirect.com/science/article/pii/S0969996123000013
  33. www.mdpi.com www.mdpi.com
    ACE2 and a Traditional Chinese Medicine Formula NRICM101 Could Alleviate the Inflammation and Pathogenic Process of Acute Lung Injury
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    mdpi.com/1648-9144/59/9/1554
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    Ezh2-dependent methylation in oral epithelia promotes secondary palatogenesis
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    onlinelibrary.wiley.com/doi/full/10.1002/bdr2.2216
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    Neural circuit models for evidence accumulation through choice-selective sequences
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    biorxiv.org/content/10.1101/2023.09.01.555612v3
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    Effect size of delayed freezing, diurnal variation, and hindgut location on the mouse fecal microbiome relative to a standardized biological variable
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    biorxiv.org/content/10.1101/2023.07.13.548851v1
  37. www.mdpi.com www.mdpi.com
    Klotho Null Mutation Indirectly Leads to Age-Related Lacrimal Gland Degeneration in Mutant Mice
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    mdpi.com/2079-7737/12/10/1328
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    Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term
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    sciencedirect.com/science/article/pii/S0022282823000937
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    Structural-functional properties of direct-pathway striatal neurons at early and chronic stages of dopamine denervation
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    onlinelibrary.wiley.com/doi/full/10.1111/ejn.16166
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    Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse
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    mdpi.com/2218-273X/13/9/1324
  41. www.biorxiv.org www.biorxiv.org
    SRRM2 splicing factor modulates cell fate in early development
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    biorxiv.org/content/10.1101/2023.12.15.571825v1
  42. www.nature.com www.nature.com
    Topologically associating domain boundaries are required for normal genome function
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    nature.com/articles/s42003-023-04819-w
  43. link.springer.com link.springer.com
    TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models
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    link.springer.com/article/10.1007/s00401-023-02615-8
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    Illuminating the druggable genome: Pathways to progress
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  45. www.pnas.org www.pnas.org
    Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs
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    pnas.org/doi/abs/10.1073/pnas.2315282120
  46. esmed.org esmed.org
    Why Angiotensin II is a Poor Choice for Circulatory Support of Ventilated COVID-19 Patients Compared to Vasopressin
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  47. www.biorxiv.org www.biorxiv.org
    FAM210B is dispensable for erythroid differentiation in adult mice
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    biorxiv.org/content/10.1101/2023.09.26.559581v1
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    Illuminating the understudied GPCR-ome
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    CCN1 expression is regulated by mechanical stimuli in tendons
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    PANEL 3: Otitis media animal models, cell culture, tissue regeneration & pathophysiology
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    sciencedirect.com/science/article/pii/S0165587623003816
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    Web-Based Resources to Investigate Protease Function
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  52. www.mdpi.com www.mdpi.com
    Standardized Complex Gut Microbiomes Influence Fetal Growth, Food Intake, and Adult Body Weight in Outbred Mice
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    mdpi.com/2076-2607/11/2/484
  53. www.sciencedirect.com www.sciencedirect.com
    Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapy
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    sciencedirect.com/science/article/pii/S2589958923000038
  54. Dec 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroscience of Disease: Human KCNQ5 de novo mutations underlie epilepsy and intellectual disability
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    ncbi.nlm.nih.gov/pmc/articles/PMC9236882/
  56. www.biorxiv.org www.biorxiv.org
    A conditional null allele of Dync1h1 enables targeted analyses of dynein roles in neuronal length sensing and neurological disorders
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    biorxiv.org/content/10.1101/2022.02.20.481176v1
  57. content.iospress.com content.iospress.com
    The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer’s Disease
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  58. academic.oup.com academic.oup.com
    Centralizing neurofibromatosis experimental tool knowledge with the NF Research Tools Database
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    academic.oup.com/database/article/doi/10.1093/database/baac045/6613566
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mouse mutagenesis and phenotyping to generate models of development and disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11275630/
  60. content.iospress.com content.iospress.com
    JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad215370
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic Strategies to Study T Cell Development
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  62. www.biorxiv.org www.biorxiv.org
    A HUMANIZED FCRN TRANSGENIC MOUSE FOR PRECLINICAL PHARMACOKINETICS STUDIES
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    biorxiv.org/content/10.1101/2022.10.24.513622v1
  63. www.jneurosci.org www.jneurosci.org
    T-Type Ca2+ Channels Boost Neurotransmission in Mammalian Cone Photoreceptors
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    jneurosci.org/content/42/33/6325
  64. Oct 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of WNK3 kinase signaling reduces brain damage and accelerates neurological recovery after stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC4643659/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC5381450/
  67. Jun 2023
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by Angiotensin-(1-7)
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    pmc.ncbi.nlm.nih.gov/articles/PMC10881191/
  69. May 2023
  70. www.mdpi.com www.mdpi.com
    [124I]IBETA: A New A&beta; Plaque Positron Emission Tomography Imaging Agent for Alzheimer&rsquo;s Disease
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    mdpi.com/1420-3049/27/14/4552/htm
  71. pubs.acs.org pubs.acs.org
    Novologue Therapy Requires Heat Shock Protein 70 and Thioredoxin-Interacting Protein to Improve Mitochondrial Bioenergetics and Decrease Mitophagy in Diabetic Sensory Neurons
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    pubs.acs.org/doi/10.1021/acschemneuro.1c00340
  72. ejnmmires.springeropen.com ejnmmires.springeropen.com
    [18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice
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    ejnmmires.springeropen.com/articles/10.1186/s13550-022-00914-x
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differential Responses to Sigma-1 or Sigma-2 Receptor Ablation in Adiposity, Fat Oxidation, and Sexual Dimorphism
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    pmc.ncbi.nlm.nih.gov/articles/PMC9506228/
  74. asbmr.onlinelibrary.wiley.com asbmr.onlinelibrary.wiley.com
    Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice
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    asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.4323
  75. www.embopress.org www.embopress.org
    Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium
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    embopress.org/doi/full/10.15252/embr.202153576
  76. www.embopress.org www.embopress.org
    PKM2-TMEM33 axis regulates lipid homeostasis in cancer cells by controlling SCAP stability
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    embopress.org/doi/full/10.15252/embj.2021108065
  77. anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com
    Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and non-canonical Wnt signaling
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    anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/dvdy.533
  78. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    5-HT3Rs Maintain Hippocampal LTP in a CB1R-GABAA-Dependent Manner for Spatial Memory
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.15793
  79. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Ablation of PDE4B protects from Pseudomonas aeruginosa-induced acute lung injury in mice by ameliorating the cytostorm and associated hypothermia
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202100495R
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oligodendrogenesis is a key process for cognitive performance improvement induced by voluntary physical activity
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    onlinelibrary.wiley.com/doi/full/10.1002/glia.24155
  81. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202200982R
  82. Apr 2023
  83. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Erythroferrone contributes to iron mobilization for embryo erythropoiesis in iron-deficient mouse pregnancies
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    onlinelibrary.wiley.com/doi/full/10.1002/ajh.26680
  84. www.biorxiv.org www.biorxiv.org
    Multiple dynamic interactions from basal ganglia direct and indirect pathways mediate action selection
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    biorxiv.org/content/10.1101/2023.03.20.533567v3
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Striatal Balancing Act in Drug Addiction: Distinct Roles of Direct and Indirect Pathway Medium Spiny Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC3140647/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic quality assurance and genetic monitoring of laboratory mice and rats: FELASA Working Group Report
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    ncbi.nlm.nih.gov/pmc/articles/PMC7160752/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species
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    ncbi.nlm.nih.gov/pmc/articles/PMC7056945/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling Genetic Susceptibility to Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC7152220/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biology and Diseases of Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC7150197/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    From Mice to Humans
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    ncbi.nlm.nih.gov/pmc/articles/PMC3488608/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tet-Transgenic Rodents: a comprehensive, up-to date database
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    ncbi.nlm.nih.gov/pmc/articles/PMC3591533/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    33rd international mammalian genome conference: meeting highlights
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    Topologically Associating Domain Boundaries are Commonly Required for Normal Genome Function
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  185. www.sciencedirect.com www.sciencedirect.com
    Droplet digital PCR or quantitative PCR for in-depth genomic and functional validation of genetically altered rodents
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  186. www.nature.com www.nature.com
    Transfer efficiency and impact on disease phenotype of differing methods of gut microbiota transfer
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    nature.com/articles/s41598-022-24014-x
  187. link.springer.com link.springer.com
    ADAMTS7 Attenuates House Dust Mite-Induced Airway Inflammation and Th2 Immune Responses
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    link.springer.com/article/10.1007/s00408-022-00538-x
  188. link.springer.com link.springer.com
    Introduction to Mammalian Genome Special Issue: Mammalian Genetic Resources
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    link.springer.com/article/10.1007/s00335-022-09942-3
  189. www.jneurosci.org www.jneurosci.org
    Visual Stimulation Induces Distinct Forms of Sensitization of On-Off Direction-Selective Ganglion Cell Responses in the Dorsal and Ventral Retina
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    jneurosci.org/content/42/22/4449
  190. Feb 2023
  191. www.nature.com www.nature.com
    Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation
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    nature.com/articles/s41467-022-35732-1
  192. www.nature.com www.nature.com
    A neural substrate of sex-dependent modulation of motivation
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    nature.com/articles/s41593-022-01229-9
  193. Aug 2022
  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens
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    ncbi.nlm.nih.gov/pmc/articles/PMC4378007/
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF423 patient variants, truncations, and in-frame deletions in mice define an allele-dependent range of midline brain abnormalities
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    ncbi.nlm.nih.gov/pmc/articles/PMC7515201/
  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of genes required for eye development by high-throughput screening of mouse knockouts
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    ncbi.nlm.nih.gov/pmc/articles/PMC6303268/
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium
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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA-Seq Analysis of Microglia Reveals Time-Dependent Activation of Specific Genetic Programs following Spinal Cord Injury
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differing Complex Microbiota Alter Disease Severity of the IL-10−/− Mouse Model of Inflammatory Bowel Disease
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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Variable Colonization after Reciprocal Fecal Microbiota Transfer between Mice with Low and High Richness Microbiota
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