10,195 Matching Annotations
  1. Jul 2021
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct skeletal stem cell types orchestrate long bone skeletogenesis
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    1. scibot 23 Jul 2021
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      DOI: 10.7554/eLife.66063

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    ncbi.nlm.nih.gov/pmc/articles/PMC8289409/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic early clusters of nodal proteins contribute to node of Ranvier assembly during myelination of peripheral neurons
    1
    1. scibot 23 Jul 2021
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      DOI: 10.7554/eLife.68089

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    ncbi.nlm.nih.gov/pmc/articles/PMC8289411/
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Visualization of early oligomeric α-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]α-syn transgenic mouse model
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.1002/jnr.24927

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24927
  5. www.sciencedirect.com www.sciencedirect.com
    Asymmetric nuclear division in neural stem cells generates sibling nuclei that differ in size, envelope composition, and chromatin organization
    1
    1. scibot 23 Jul 2021
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      DOI: 10.1016/j.cub.2021.06.063

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    sciencedirect.com/science/article/pii/S0960982221008927
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    Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice
    1
    1. scibot 23 Jul 2021
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      DOI: 10.1016/j.chom.2021.06.014

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    sciencedirect.com/science/article/pii/S1931312821002961
  7. www.nature.com www.nature.com
    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1038/s41388-021-01869-4

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    nature.com/articles/s41388-021-01869-4
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    R (-)-methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamine
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.neuropharm.2021.108619

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    sciencedirect.com/science/article/pii/S0028390821001738
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    Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.stem.2021.06.004

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    sciencedirect.com/science/article/pii/S1934590921002745
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    Early invasion of the bladder wall by solitary bacteria protects UPEC from antibiotics and neutrophil swarms in an organoid model
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109351

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    sciencedirect.com/science/article/pii/S2211124721007270
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    Oxytocin in the anterior cingulate cortex attenuates neuropathic pain and emotional anxiety by inhibiting presynaptic long-term potentiation
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109411

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    sciencedirect.com/science/article/pii/S221112472100824X
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    Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109409

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    sciencedirect.com/science/article/pii/S2211124721008226
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development
    2
    1. scibot 21 Jul 2021
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      DOI: 10.7554/eLife.67718

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    2. scibot 21 Jul 2021
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      DOI: 10.7554/eLife.67718

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    ncbi.nlm.nih.gov/pmc/articles/PMC8282341/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crash landing of Vibrio cholerae by MSHA pili-assisted braking and anchoring in a viscoelastic environment
    1
    1. scibot 21 Jul 2021
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      DOI: 10.7554/eLife.60655

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    ncbi.nlm.nih.gov/pmc/articles/PMC8282333/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi
    1
    1. scibot 21 Jul 2021
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      DOI: 10.7554/eLife.67449

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    ncbi.nlm.nih.gov/pmc/articles/PMC8282336/
  16. elifesciences.org elifesciences.org
    Acid-base transporters and pH dynamics in human breast carcinomas predict proliferative activity, metastasis, and survival
    1
    1. scibot 21 Jul 2021
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      DOI: 10.7554/eLife.68447

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    elifesciences.org/articles/68447
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Respiratory and intestinal epithelial cells exhibit differential susceptibility and innate immune responses to contemporary EV-D68 isolates
    1
    1. scibot 21 Jul 2021
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      DOI: 10.7554/eLife.66687

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    ncbi.nlm.nih.gov/pmc/articles/PMC8285104/
  18. elifesciences.org elifesciences.org
    Action potential-coupled Rho GTPase signaling drives presynaptic plasticity
    1
    1. scibot 21 Jul 2021
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      DOI: 10.7554/eLife.63756

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    elifesciences.org/articles/63756
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis
    1
    1. scibot 21 Jul 2021
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      DOI: 10.7554/eLife.64872

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    ncbi.nlm.nih.gov/pmc/articles/PMC8285109/
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The ependymal cell cytoskeleton in the normal and injured spinal cord of mice
    1
    1. scibot 21 Jul 2021
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      DOI: 10.1002/jnr.24918

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24918
  21. www.sciencedirect.com www.sciencedirect.com
    Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue
    1
    1. scibot 21 Jul 2021
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      DOI: 10.1016/j.cub.2021.06.052

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    sciencedirect.com/science/article/pii/S0960982221008812
  22. www.sciencedirect.com www.sciencedirect.com
    Long-term taurine administration improves motor skills in a tubulinopathy rat model by decreasing oxidative stress and promoting myelination
    1
    1. scibot 21 Jul 2021
      RRID:SCR_0158070

      DOI: 10.1016/j.mcn.2021.103643

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    sciencedirect.com/science/article/pii/S1044743121000567
  23. link.springer.com link.springer.com
    ARA-linker-TGFαL3: a novel chimera protein to target breast cancer cells
    1
    1. scibot 20 Jul 2021
      RRID:SCR_002798

      DOI: 10.1007/s12032-021-01546-2

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    link.springer.com/article/10.1007/s12032-021-01546-2
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glutamatergic receptor expression changes in the Alzheimer's disease hippocampus and entorhinal cortex
    1
    1. scibot 17 Jul 2021
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      DOI: 10.1111/bpa.13005

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    onlinelibrary.wiley.com/doi/10.1111/bpa.13005
  25. www.sciencedirect.com www.sciencedirect.com
    Hypothalamic control of interoceptive hunger
    1
    1. scibot 17 Jul 2021
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      DOI: 10.1016/j.cub.2021.06.048

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    sciencedirect.com/science/article/pii/S0960982221008770
  26. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    PTPN5 promotes follicle-stimulating hormone secretion through regulating intracellular calcium homeostasis
    1
    1. scibot 17 Jul 2021
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      DOI: 10.1096/fj.202002752RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002752RR
  27. www.sciencedirect.com www.sciencedirect.com
    Retrieval and purification of human β cells from stem cell-derived islet engrafted mice
    1
    1. scibot 17 Jul 2021
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      DOI: 10.1016/j.xpro.2021.100675

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    sciencedirect.com/science/article/pii/S2666166721003828
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response
    1
    1. scibot 17 Jul 2021
      RRID:SCR_015807

      DOI: 10.7554/eLife.61407

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    ncbi.nlm.nih.gov/pmc/articles/PMC8279762/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low serum IgG4 level: a potential diagnostic biomarker for IgA nephropathy
    2
    1. scibot 16 Jul 2021
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      DOI: 10.21037/atm-20-7007

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      DOI: 10.21037/atm-20-7007

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    ncbi.nlm.nih.gov/pmc/articles/PMC8246212/
  30. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Crosstalk between beta-adrenergic and insulin signaling mediates mechanistic target of rapamycin hyperactivation in liver of high-fat diet-fed male mice
    2
    1. scibot 16 Jul 2021
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      DOI: 10.14814/phy2.14958

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    2. scibot 10 Jul 2021
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      DOI: 10.14814/phy2.14958

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    physoc.onlinelibrary.wiley.com/doi/full/10.14814/phy2.14958
  31. www.sciencedirect.com www.sciencedirect.com
    Myelination induces axonal hotspots of synaptic vesicle fusion that promote sheath growth
    1
    1. scibot 16 Jul 2021
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      DOI: 10.1016/j.cub.2021.06.036

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    sciencedirect.com/science/article/pii/S0960982221008319
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis
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    1. scibot 16 Jul 2021
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      DOI: 10.7554/eLife.66942

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    ncbi.nlm.nih.gov/pmc/articles/PMC8277355/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IgV somatic mutation of human anti–SARS-CoV-2 monoclonal antibodies governs neutralization and breadth of reactivity
    1
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      DOI: 10.1172/jci.insight.147386

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    ncbi.nlm.nih.gov/pmc/articles/PMC8262290/
  34. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma
    1
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      DOI: 10.1158/1078-0432.CCR-20-4575

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    clincancerres.aacrjournals.org/content/27/12/3339
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-COV-2 Spike binding to ACE2 in living cells monitored by TR-FRET
    2
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      DOI: 10.1016/j.chembiol.2021.06.008

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      DOI: 10.1016/j.chembiol.2021.06.008

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    ncbi.nlm.nih.gov/pmc/articles/PMC8249686/
  36. mcr.aacrjournals.org mcr.aacrjournals.org
    An IFNγ/STAT1/JMJD3 Axis Induces ZEB1 Expression and Promotes Aggressiveness in Lung Adenocarcinoma
    1
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      DOI: 10.1158/1541-7786.MCR-20-0948

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    mcr.aacrjournals.org/content/19/7/1234
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis
    1
    1. scibot 14 Jul 2021
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      DOI: 10.1111/bph.15438

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    ncbi.nlm.nih.gov/pmc/articles/PMC8251890/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Entry of antiepileptic drugs (valproate and lamotrigine) into the developing rat brain
    1
    1. scibot 14 Jul 2021
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      DOI: 10.12688/f1000research.52607.1

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    ncbi.nlm.nih.gov/pmc/articles/PMC8207807/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis
    1
    1. scibot 14 Jul 2021
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      DOI: 10.1080/19490976.2021.1927633

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    ncbi.nlm.nih.gov/pmc/articles/PMC8158032/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism
    1
    1. scibot 14 Jul 2021
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      DOI: 10.1523/ENEURO.0066-21.2021

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    l-α-aminoadipate causes astrocyte pathology with negative impact on mouse hippocampal synaptic plasticity and memory
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    AMPA induced cognitive impairment in rats: Establishing the role of endoplasmic reticulum stress inhibitor, 4-PBA
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    Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFAT signaling in human mesenchymal stromal cells affects extracellular matrix remodeling and antifungal immune responses
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    Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions
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    Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction
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    Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways
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    Development of red genetically encoded biosensor for visualization of intracellular glucose dynamics
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    PPP2R4 dysfunction promotes KRAS-mutant lung adenocarcinoma development and mediates opposite responses to MEK and mTOR inhibition
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  93. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Schwann cell precursors generate sympathoadrenal system during zebrafish development
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    The voltage-gated proton channel Hv1 promotes microglia-astrocyte communication and neuropathic pain after peripheral nerve injury
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    UNC-2 CaV2 channel localization at presynaptic active zones depends on UNC-10/RIM and SYD-2/Liprin-α in Caenorhabditis elegans
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  96. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin.
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    Development and Characterization of Novel Endoxifen-Resistant Breast Cancer Cell Lines Highlight Numerous Differences from Tamoxifen-Resistant Models
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    Development and Validation of a Novel Nomogram for Individualized Prediction of Survival in Cancer of Unknown Primary
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    Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
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  100. cancerres.aacrjournals.org cancerres.aacrjournals.org
    STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer
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    A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrinsic OXPHOS limitations underlie cellular bioenergetics in leukemia
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    A novel CRISPR-based malaria diagnostic capable of Plasmodium detection, species differentiation, and drug-resistance genotyping
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    Bioreactor Suspension Culture: Differentiation and Production of Cardiomyocyte Spheroids From Human Induced Pluripotent Stem Cells
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      DOI: 10.3389/fbioe.2021.674260

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    Fetal Zone Steroids and Estrogen Show Sex Specific Effects on Oligodendrocyte Precursor Cells in Response to Oxidative Damage
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    Estrogen receptor β contributes to both hypertension and hypothalamic plasticity in a mouse model of peri-menopause
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    Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2
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    Roles of adenosine A1 receptors in the regulation of SFK activity in the rat forebrain
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    The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression
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    Uncovering a ‘sensitive window’ of multisensory and motor neuroplasticity in the cerebrum and cerebellum of male and female starlings
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    Multi-Platform Metabolomics Analyses Revealed the Complexity of Serum Metabolites in LPS-Induced Neuroinflammed Rats Treated with Clinacanthus nutans Aqueous Extract
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    Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity
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    Activation of nuclear receptor PXR induces atherogenic lipids and PCSK9 through SREBP2‐mediated mechanism
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      DOI: 10.1111/bph.15433

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    Novel Dent Disease 1 cellular models reveal biological processes underlying ClC-5 loss-of-function
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    Sexually Dimorphic Perineuronal Nets in the Rodent and Primate Reproductive Circuit
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    Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity
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    Structural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Role of Satb1 and Satb2 Transcription Factors in the Glutamate Receptors Expression and Ca2+ Signaling in the Cortical Neurons In Vitro
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    Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene
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    Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription
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    A diverse collection of B cells responded to HIV infection in infant BG505
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    Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK
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    The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation
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    Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior
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    Identification and validation of selective deubiquitinase inhibitors
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    Antibiotic-induced disruption of the microbiome exacerbates chemotherapy-induced diarrhoea and can be mitigated with autologous faecal microbiota transplantation
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    High‐Throughput Screening of Compound Neurotoxicity Using 3D‐Cultured Neural Stem Cells on a 384‐Pillar Plate
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    Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis
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    Voltage-clamp fluorometry analysis of structural rearrangements of ATP-gated channel P2X2 upon hyperpolarization
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    Somatostatin-expressing parafacial neurons are CO2/H+ sensitive and regulate baseline breathing
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  167. www.nature.com www.nature.com
    TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice
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  168. www.sciencedirect.com www.sciencedirect.com
    C. elegans survival assays to discern global and transcription-coupled nucleotide excision repair
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    Defining corneal chemical burns: A novel exact and adjustable ocular model
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  170. elifesciences.org elifesciences.org
    Wnt- and glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division
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  171. elifesciences.org elifesciences.org
    Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta
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  172. elifesciences.org elifesciences.org
    Optogenetic strategies for high-efficiency all-optical interrogation using blue-light-sensitive opsins
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      DOI: 10.7554/eLife.63359

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  173. elifesciences.org elifesciences.org
    Cellular, circuit and transcriptional framework for modulation of itch in the central amygdala
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  174. elifesciences.org elifesciences.org
    Pore mutation N617D in the skeletal muscle DHPR blocks Ca2+ influx due to atypical high-affinity Ca2+ binding
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    Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality
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    Bacterial genotoxins induce T cell senescence
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    The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models
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  178. science.sciencemag.org science.sciencemag.org
    Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice
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  179. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Neuromuscular junction instability and altered intracellular calcium handling as early determinants of force loss during unloading in humans
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    Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology
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  182. elifesciences.org elifesciences.org
    Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum
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    SARS-CoV-2 infection induces beta cell transdifferentiation
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    Efficient extra-mitochondrial aerobic ATP synthesis in neuronal membrane systems
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection
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    Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia
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      DOI: 10.1016/j.cub.2021.04.079

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    A Novel Methodology Using Dexamethasone to Induce Neuronal Differentiation in the CNS-Derived Catecholaminergic CAD Cells
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      DOI: 10.1007/s10571-021-01109-z

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  188. www.mdpi.com www.mdpi.com
    Identification of Circulating Diagnostic Biomarkers for Coronary Microvascular Disease in Postmenopausal Women Using Machine-Learning Techniques
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  189. journals.sagepub.com journals.sagepub.com
    B and T Lymphocyte Densities Remain Stable With Age in Human Cortex - Kacey Berry, Daniela S. Farias-Itao, Lea T. Grinberg, Edward D. Plowey, Julie A. Schneider, Roberta D. Rodriguez, Claudia K. Suemoto, Marion S. Buckwalter, 2021
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Taurine Increases Zinc Preconditioning-Induced Prevention of Nitrosative Stress, Metabolic Alterations, and Motor Deficits in Young Rats following Intrauterine Ischemia
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  191. www.frontiersin.org www.frontiersin.org
    Patient Derived Colonoids as Drug Testing Platforms–Critical Importance of Oxygen Concentration
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      DOI: 10.3389/fphar.2021.679741

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  192. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ACSA-2 and GLAST classify subpopulations of multipotent and glial-restricted cerebellar precursors
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      DOI: 10.1002/jnr.24842

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    The synaptic blocker botulinum toxin A decreases the density and complexity of oligodendrocyte precursor cells in the adult mouse hippocampus
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      DOI: 10.1002/jnr.24856

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  194. onlinelibrary.wiley.com onlinelibrary.wiley.com
    HIV-induced neuroinflammation inhibits oligodendrocyte maturation via glutamate-dependent activation of the PERK arm of the integrated stress response
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      DOI: 10.1002/glia.24033

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  195. www.nature.com www.nature.com
    MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer
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      DOI: 10.1038/s41523-021-00273-1

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  196. elifesciences.org elifesciences.org
    An excitatory lateral hypothalamic circuit orchestrating pain behaviors in mice
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      DOI: 10.7554/eLife.66446

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  197. www.nature.com www.nature.com
    Pericentromeric Satellite III transcripts induce etoposide resistance
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      DOI: 10.1038/s41419-021-03810-9

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