10,211 Matching Annotations
  1. May 2021
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    Distinct effects on cAMP signaling of carbamazepine and its structural derivatives do not correlate with their clinical efficacy in epilepsy
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      DOI: 10.1016/j.ejphar.2020.173413

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    sciencedirect.com/science/article/pii/S0014299920305057
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    A single-cell analysis of the Arabidopsis vegetative shoot apex
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      DOI: 10.1016/j.devcel.2021.02.021

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    sciencedirect.com/science/article/pii/S1534580721001611
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    An organelle-tethering mechanism couples flagellation to cell division in bacteria
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      DOI: 10.1016/j.devcel.2021.01.013

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    sciencedirect.com/science/article/pii/S153458072100071X
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    FEBS Press
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      DOI: 10.1002/1878-0261.12953

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    A BIN2-GLK1 Signaling Module Integrates Brassinosteroid and Light Signaling to Repress Chloroplast Development in the Dark
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    1. scibot 06 May 2021
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    sciencedirect.com/science/article/pii/S153458072030976X
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    Transient Nodal Signaling in Left Precursors Coordinates Opposed Asymmetries Shaping the Heart Loop
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      DOI: 10.1016/j.devcel.2020.10.008

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    sciencedirect.com/science/article/pii/S153458072030798X
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    DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation
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    A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation
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    sciencedirect.com/science/article/pii/S1534580720306274
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    The GSK3-like Kinase BIN2 Is a Molecular Switch between the Salt Stress Response and Growth Recovery in Arabidopsis thaliana
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    sciencedirect.com/science/article/pii/S1534580720306298
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    Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway
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    1. scibot 05 May 2021
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    A Weak Link with Actin Organizes Tight Junctions to Control Epithelial Permeability
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    1. scibot 05 May 2021
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    sciencedirect.com/science/article/pii/S1534580720305979
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    A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
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    ncbi.nlm.nih.gov/pmc/articles/PMC7606764/
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    Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis
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    ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization
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    Efferent feedback controls bilateral auditory spontaneous activity
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      DOI: 10.1038/s41467-021-22796-8

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    nature.com/articles/s41467-021-22796-8
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ architecture of neuronal α-Synuclein inclusions
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      DOI: 10.1038/s41467-021-22108-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC8046968/
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    Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology
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      DOI: 10.7554/eLife.66904

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    ncbi.nlm.nih.gov/pmc/articles/PMC8075583/
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    Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair
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      DOI: 10.4049/jimmunol.1901263

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    ncbi.nlm.nih.gov/pmc/articles/PMC7443363/
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    Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake
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      DOI: 10.1016/j.celrep.2021.109087

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    sciencedirect.com/science/article/pii/S2211124721004204
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    Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation
    1
    1. scibot 04 May 2021
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      DOI: 10.1016/j.devcel.2020.04.018

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    Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion
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    1. scibot 04 May 2021
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      DOI: 10.1016/j.cub.2020.08.046

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    sciencedirect.com/science/article/pii/S0960982220312367
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    Prefrontal Cortical Projection Neurons Targeting Dorsomedial Striatum Control Behavioral Inhibition
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      DOI: 10.1016/j.cub.2020.08.031

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    sciencedirect.com/science/article/pii/S0960982220311854
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    Retinal Inputs to the Thalamus Are Selectively Gated by Arousal
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      DOI: 10.1016/j.cub.2020.07.065

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    sciencedirect.com/science/article/pii/S0960982220310903
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    A randomized trial of adjuvant chemotherapy versus observation in patients with nasopharyngeal carcinoma with detectable post-radiotherapy pEBV DNA
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      DOI: 10.1158/1078-0432.CCR-20-3519

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    HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis
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      DOI: 10.1016/j.stem.2021.02.008

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    The Neuroprotective Beta Amyloid Hexapeptide Core Reverses Deficits in Synaptic Plasticity in the 5xFAD APP/PS1 Mouse Model
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      DOI: 10.3389/fnmol.2021.576038

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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of functionally distinct macrophage subpopulations in Drosophila
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      DOI: 10.7554/eLife.58686

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    ncbi.nlm.nih.gov/pmc/articles/PMC8062135/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gamma rhythms and visual information in mouse V1 specifically modulated by somatostatin+ neurons in reticular thalamus
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      DOI: 10.7554/eLife.61437

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    ncbi.nlm.nih.gov/pmc/articles/PMC8064751/
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    PMCA-generated prions from the olfactory mucosa of patients with Fatal Familial Insomnia cause prion disease in mice
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      DOI: 10.7554/eLife.65311

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    GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys
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      DOI: 10.1016/j.xcrm.2021.100263

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  32. Apr 2021
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    An isocaloric moderately high-fat diet extends lifespan in male rats and Drosophila
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      DOI: 10.1016/j.cmet.2020.12.017

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    Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation
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    Platelets Facilitate the Wound-Healing Capability of Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic Reprogramming
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      DOI: 10.1016/j.cmet.2020.12.006

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    Central Alteration in Peripheral Neuropathy of Trembler-J Mice: Hippocampal pmp22 Expression and Behavioral Profile in Anxiety Tests
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      DOI: 10.3390/biom11040601

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    mdpi.com/2218-273X/11/4/601
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    Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
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      DOI: 10.1016/j.cmet.2020.10.020

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    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
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      DOI: 10.1016/j.cmet.2020.10.005

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    Insulin and Leptin/Upd2 Exert Opposing Influences on Synapse Number in Fat-Sensing Neurons
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      DOI: 10.1016/j.cmet.2020.08.017

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    ncbi.nlm.nih.gov/pmc/articles/PMC7642105/
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    A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes
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      DOI: 10.1016/j.cmet.2020.08.007

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    Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation
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      DOI: 10.1007/s00018-021-03818-6

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    link.springer.com/article/10.1007/s00018-021-03818-6
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    Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation
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      DOI: 10.1016/j.cmet.2020.07.005

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    SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery
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      DOI: 10.1016/j.celrep.2021.109055

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    ncbi.nlm.nih.gov/pmc/articles/PMC8043574/
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    Local Mitochondrial ATP Production Regulates Endothelial Fatty Acid Uptake and Transport
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    Diversity in striatal synaptic circuits arises from distinct embryonic progenitor pools in the ventral telencephalon
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    Lateral Habenula Mediates Defensive Responses Only When Threat and Safety Memories Are in Conflict
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    LncRNA CALB2 sponges miR-30b-3p to promote odontoblast differentiation of human dental pulp stem cells via up-regulating RUNX2
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    MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23
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    Modulation of stimulated dopamine release in rat nucleus accumbens shell by GABA in vitro: Effect of sub‐chronic phencyclidine pretreatment
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    Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis
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    mTOR inhibitor improves autistic-like behaviors related to Tsc2 haploinsufficiency but not following developmental status epilepticus
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    Cascade diversification directs generation of neuronal diversity in the hypothalamus
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    Phasic Off responses of auditory cortex underlie perception of sound duration
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    Improved HIV-positive infant survival is correlated with high levels of HIV-specific ADCC activity in multiple cohorts
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    Hypoxia-induced depression of synaptic transmission becomes irreversible by intracellular accumulation of non-excitatory amino acids
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    In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury
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    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
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    Dysregulated CRMP Mediates Circadian Deficits in a Drosophila Model of Fragile X Syndrome
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    Structures of the MHC-I molecule BF2*1501 disclose the preferred presentation of an H5N1 virus-derived epitope
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    Proline-rich 11 (PRR11) drives F-actin assembly by recruiting the actin-related protein 2/3 complex in human non-small cell lung carcinoma
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    Dual blockade of EGFR and CDK4/6 delays head and neck squamous cell carcinoma progression by inducing metabolic rewiring
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    Quantifying anhedonia-like symptoms in marmosets using appetitive Pavlovian conditioning
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    Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C
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    Repetitive Blast Exposure Produces White Matter Axon Damage without Subsequent Myelin Remodeling: <italic toggle="yes">In Vivo</italic> Analysis of Brain Injury Using Fluorescent Reporter Mice
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    Low expression of the PPARγ-regulated gene thioredoxin-interacting protein accompanies human melanoma progression and promotes experimental lung metastases
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    Inhibition of Acyl-CoA Synthetase Long-Chain Family Member 4 Facilitates Neurological Recovery After Stroke by Regulation Ferroptosis
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    Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor
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    SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses
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    Infection with a newly designed dual fluorescent reporter HIV-1 effectively identifies latently infected CD4+ T cells
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    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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    Astragaloside IV prevents Aβ1-42 oligomers-induced memory impairment and hippocampal cell apoptosis by promoting PPARγ/BDNF signaling pathway
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    Zika virus NS1 affects the junctional integrity of human brain microvascular endothelial cells
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    Ionizing radiation induces BH4 deficiency by downregulating GTP-cyclohydrolase 1, a novel target for preventing and treating radiation enteritis
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    Non-selective orexin-receptor antagonist attenuates stress-re-stress-induced core PTSD-like symptoms in rats: behavioural and neurochemical analyses
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    Properties of multivesicular release from mouse rod photoreceptors support transmission of single-photon responses
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    Complement C5a promotes antigen cross-presentation by Peyer’s patch monocyte-derived dendritic cells and drives a protective CD8+ T cell response
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    Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes
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    The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
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    Rapid eye movement sleep deprivation impairs neuronal plasticity and reduces hippocampal neuronal arborization in male albino rats: Noradrenaline is involved in the process
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    Investigating oligodendrocyte connexins: Heteromeric interactions between Cx32 and mutant or wild‐type forms of Cx47 do not contribute to or modulate gap junction function
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    Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance
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      DOI: 10.3390/cancers13071648

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    Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
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    Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation
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    Declining lamin B1 expression mediates age-dependent decreases of hippocampal stem cell activity
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    Functional interrogation of DNA damage response variants with base editing screens
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    Nucleus accumbens neurons expressing dopamine D1 receptors modulate states of consciousness in sevoflurane anesthesia
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    Neuronal Nitric Oxide Synthase in Nucleus Accumbens Specifically Mediates Susceptibility to Social Defeat Stress through Cyclin-Dependent Kinase 5
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    Parallel synaptic acetylcholine signals facilitate large monopolar cell repolarization and modulate visual behavior in Drosophila
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    Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation
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    CHPG enhances BDNF and myelination in cuprizone‐treated mice through astrocytic metabotropic glutamate receptor 5
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    Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain
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    NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation
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    Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
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    Inactivation of Cys674 in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase
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    Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate
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    Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation
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    Molecular pathways behind acquired obesity: adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI
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    Integrated regulatory network in Pseudomonas syringae reveals dynamics of virulence
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    Neddylation is required for presynaptic clustering of mGlu7 and maturation of presynaptic terminals
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    Excitatory granule neuron precursors orchestrate laminar localization and differentiation of cerebellar inhibitory interneuron subtypes
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  167. Mar 2021
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein and Signaling Pathway Responses to rhIL-6 Intervention Before Lobaplatin Treatment in Osteosarcoma Cells
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  169. journals.sagepub.com journals.sagepub.com
    Urokinase-type plasminogen activator promotes N-cadherin-mediated synaptic recovery in the ischemic brain - Ariel Diaz, Paola Merino, Patrick McCann, Manuel A Yepes, Laura G Quiceno, Enrique Torre, Amelia Tomkins, Xiaodong Zhang, Chadwick M Hales, Frank C Tong, Manuel Yepes, 2021
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  170. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enriching neural stem cell and anti‐inflammatory glial phenotypes with electrical stimulation after traumatic brain injury in male rats
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    Discovery of a σ1 receptor antagonist by combination of unbiased cell painting and thermal proteome profiling
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    Interleukin-10 does not contribute to the anti-contractile nature of PVAT in health
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    Atoh7-independent specification of retinal ganglion cell identity
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  176. elifesciences.org elifesciences.org
    Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs, and mRNAs in live bacterial cells
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment
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  180. elifesciences.org elifesciences.org
    Multiple time-scales of decision-making in the hippocampus and prefrontal cortex
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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells
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      DOI: 10.1158/2643-3230.BCD-20-0161

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  182. academic.oup.com academic.oup.com
    Brain Volumes in Mice are Smaller at Birth After Term or Preterm Cesarean Section Delivery
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  183. www.frontiersin.org www.frontiersin.org
    C21orf91 Regulates Oligodendroglial Precursor Cell Fate—A Switch in the Glial Lineage?
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      DOI: 10.3389/fncel.2021.653075

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    Cyclopiazonic Acid-Induced Ca2+ Store Depletion Initiates Endothelium-Dependent Hyperpolarization-Mediated Vasorelaxation of Mesenteric Arteries in Healthy and Colitis Mice
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  185. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Extracellular signal‐regulated kinases 2 (Erk2) and Erk5 in the central nervous system differentially contribute to central sensitization in male mice
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    Extracellular signal‐regulated kinase regulates microglial immune responses in Alzheimer’s disease
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      DOI: 10.1002/jnr.24829

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  187. www.frontiersin.org www.frontiersin.org
    Pharmacologic Inhibition of ADAM10 Attenuates Brain Tissue Loss, Axonal Injury and Pro-inflammatory Gene Expression Following Traumatic Brain Injury in Mice
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      DOI: 10.3389/fcell.2021.661462

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    Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection
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      DOI: 10.7554/eLife.65958

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    Oral efficacy of Δ(9)-tetrahydrocannabinol and cannabidiol in a mouse neuropathic pain model
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    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
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  191. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ground state depletion microscopy as a tool for studying microglia–synapse interactions
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis
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    Identification of novel myelin repair drugs by modulation of oligodendroglial differentiation competence
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      DOI: 10.1016/j.ebiom.2021.103276

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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR
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      DOI: 10.7554/eLife.66638

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    Protocol for high-throughput compound screening using flow cytometry in THP-1 cells
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      DOI: 10.1016/j.xpro.2021.100400

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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglial trogocytosis and the complement system regulate axonal pruning in vivo
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  198. elifesciences.org elifesciences.org
    Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex
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      DOI: 10.7554/eLife.61432

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    Enriched environment ameliorates chronic temporal lobe epilepsy‐induced behavioral hyperexcitability and restores synaptic plasticity in CA3–CA1 synapses in male Wistar rats
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      DOI: 10.1002/jnr.24823

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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic Conditions Promote Rhythmic Contractile Oscillations Mediated by Voltage-Gated Sodium Channels Activation in Human Arteries
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      DOI: 10.3390/ijms22052570

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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transglutaminases Are Active in Perivascular Adipose Tissue
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    Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells
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