10,821 Matching Annotations
  1. Jul 2021
  2. elifesciences.org elifesciences.org
    Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism
    1
    1. scibot 27 Jul 2021
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      DOI: 10.7554/eLife.22759

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    elifesciences.org/content/6/e22759
  3. journal.frontiersin.org journal.frontiersin.org
    Crossed Cerebellar Atrophy of the Lateral Cerebellar Nucleus in an Endothelin-1-Induced, Rodent Model of Ischemic Stroke
    2
    1. scibot 27 Jul 2021
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      DOI: 10.3389/fnagi.2017.00010

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      DOI: 10.3389/fnagi.2017.00010

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    journal.frontiersin.org/article/10.3389/fnagi.2017.00010/full
  4. elifesciences.org elifesciences.org
    A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)
    6
    1. scibot 27 Jul 2021
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      DOI: 10.7554/eLife.22706

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      DOI: 10.7554/eLife.22706

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    3. scibot 27 Jul 2021
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    6. scibot 27 Jul 2021
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    Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport
    2
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      DOI: 10.1016/j.neuron.2017.03.027

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      DOI: 10.1016/j.neuron.2017.03.027

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    sciencedirect.com/science/article/pii/S0896627317302398
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CaMKII Signaling Stimulates Mef2c Activity In Vitro but Only Minimally Affects Murine Long Bone Development in vivo
    2
    1. scibot 27 Jul 2021
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      DOI: 10.3389/fcell.2017.00020

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      DOI: 10.3389/fcell.2017.00020

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  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Adult Ciliary Neurotrophic Factor Receptors Help Maintain Facial Motor Neuron Choline Acetyltransferase Expression In Vivo Following Nerve Crush
    2
    1. scibot 27 Jul 2021
      SCR_002798

      DOI: 10.1002/cne.24126

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      SCR_002798

      DOI: 10.1002/cne.24126

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  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenomic and metabolic responses of hypothalamic POMC neurons to gestational nicotine exposure in adult offspring
    2
    1. scibot 27 Jul 2021
      SCR_002798

      DOI: 10.1186/s13073-016-0348-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC5015242/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ear2 Deletion Causes Early Memory and Learning Deficits in APP/PS1 Mice
    1
    1. scibot 27 Jul 2021
      rid_000081

      DOI: 10.1523/JNEUROSCI.4027-13.2014

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    ncbi.nlm.nih.gov/pmc/articles/PMC4147626/
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sequential MAVS and MyD88/TRIF signaling triggers anti-viral responses of tick-borne encephalitis virus-infected murine astrocytes
    1
    1. scibot 24 Jul 2021
      RRID:SCR_002798

      DOI: 10.1002/jnr.24923

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24923
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    Functional diversity for body actions in the mesencephalic locomotor region
    1
    1. scibot 24 Jul 2021
      RRID:SCR_002798

      DOI: 10.1016/j.cell.2021.07.002

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    sciencedirect.com/science/article/pii/S009286742100828X
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    Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis
    1
    1. scibot 24 Jul 2021
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      DOI: 10.1016/j.cmet.2021.07.002

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    sciencedirect.com/science/article/pii/S1550413121003181
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    Protocol for tissue clearing and 3D analysis of dopamine neurons in the developing mouse midbrain
    1
    1. scibot 24 Jul 2021
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      DOI: 10.1016/j.xpro.2021.100669

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    sciencedirect.com/science/article/pii/S2666166721003762
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long ncRNA MALAT1 promotes cell proliferation, migration, and invasion in prostate cancer via sponging miR-145
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.21037/tau-20-1526

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    ncbi.nlm.nih.gov/pmc/articles/PMC8261405/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased plasma levels of damage-associated molecular patterns during systemic anticancer therapy in patients with advanced lung cancer
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.21037/tlcr-21-92

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    ncbi.nlm.nih.gov/pmc/articles/PMC8264341/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptome profiling of the Olig2-expressing astrocyte subtype reveals their unique molecular signature
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.1016/j.isci.2021.102806

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    ncbi.nlm.nih.gov/pmc/articles/PMC8281609/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA-RNA hybrids at DSBs interfere with repair by homologous recombination
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.7554/eLife.69881

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    ncbi.nlm.nih.gov/pmc/articles/PMC8289408/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct skeletal stem cell types orchestrate long bone skeletogenesis
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.7554/eLife.66063

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    ncbi.nlm.nih.gov/pmc/articles/PMC8289409/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic early clusters of nodal proteins contribute to node of Ranvier assembly during myelination of peripheral neurons
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.7554/eLife.68089

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    ncbi.nlm.nih.gov/pmc/articles/PMC8289411/
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Visualization of early oligomeric α-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]α-syn transgenic mouse model
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.1002/jnr.24927

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24927
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asymmetric nuclear division in neural stem cells generates sibling nuclei that differ in size, envelope composition, and chromatin organization
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.1016/j.cub.2021.06.063

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    ncbi.nlm.nih.gov/pmc/articles/PMC8491657/
  22. www.sciencedirect.com www.sciencedirect.com
    Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice
    1
    1. scibot 23 Jul 2021
      RRID:SCR_002798

      DOI: 10.1016/j.chom.2021.06.014

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    sciencedirect.com/science/article/pii/S1931312821002961
  23. www.nature.com www.nature.com
    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC
    1
    1. scibot 22 Jul 2021
      RRID:SCR_002798

      DOI: 10.1038/s41388-021-01869-4

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    nature.com/articles/s41388-021-01869-4
  24. www.sciencedirect.com www.sciencedirect.com
    R (-)-methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamine
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.neuropharm.2021.108619

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    sciencedirect.com/science/article/pii/S0028390821001738
  25. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.stem.2021.06.004

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    sciencedirect.com/science/article/pii/S1934590921002745
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    Early invasion of the bladder wall by solitary bacteria protects UPEC from antibiotics and neutrophil swarms in an organoid model
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109351

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    sciencedirect.com/science/article/pii/S2211124721007270
  27. www.sciencedirect.com www.sciencedirect.com
    Oxytocin in the anterior cingulate cortex attenuates neuropathic pain and emotional anxiety by inhibiting presynaptic long-term potentiation
    1
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      DOI: 10.1016/j.celrep.2021.109411

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    sciencedirect.com/science/article/pii/S221112472100824X
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    Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
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      DOI: 10.1016/j.celrep.2021.109409

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    sciencedirect.com/science/article/pii/S2211124721008226
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development
    2
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      DOI: 10.7554/eLife.67718

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      DOI: 10.7554/eLife.67718

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    ncbi.nlm.nih.gov/pmc/articles/PMC8282341/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crash landing of Vibrio cholerae by MSHA pili-assisted braking and anchoring in a viscoelastic environment
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      DOI: 10.7554/eLife.60655

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    ncbi.nlm.nih.gov/pmc/articles/PMC8282333/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi
    1
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      DOI: 10.7554/eLife.67449

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    ncbi.nlm.nih.gov/pmc/articles/PMC8282336/
  32. elifesciences.org elifesciences.org
    Acid-base transporters and pH dynamics in human breast carcinomas predict proliferative activity, metastasis, and survival
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      DOI: 10.7554/eLife.68447

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    elifesciences.org/articles/68447
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Respiratory and intestinal epithelial cells exhibit differential susceptibility and innate immune responses to contemporary EV-D68 isolates
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      DOI: 10.7554/eLife.66687

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    ncbi.nlm.nih.gov/pmc/articles/PMC8285104/
  34. elifesciences.org elifesciences.org
    Action potential-coupled Rho GTPase signaling drives presynaptic plasticity
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    1. scibot 21 Jul 2021
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      DOI: 10.7554/eLife.63756

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    elifesciences.org/articles/63756
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis
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      DOI: 10.7554/eLife.64872

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    ncbi.nlm.nih.gov/pmc/articles/PMC8285109/
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The ependymal cell cytoskeleton in the normal and injured spinal cord of mice
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      DOI: 10.1002/jnr.24918

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24918
  37. www.sciencedirect.com www.sciencedirect.com
    Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue
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    Long-term taurine administration improves motor skills in a tubulinopathy rat model by decreasing oxidative stress and promoting myelination
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    Crosstalk between beta-adrenergic and insulin signaling mediates mechanistic target of rapamycin hyperactivation in liver of high-fat diet-fed male mice
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    Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma
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    An IFNγ/STAT1/JMJD3 Axis Induces ZEB1 Expression and Promotes Aggressiveness in Lung Adenocarcinoma
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    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
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    Pathogenic Activation and Therapeutic Blockage of Fc Alpha Receptor-Expressing Polymorphonuclear Leukocytes in IgA Pemphigus
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    Drug synergy of combinatory treatment with remdesivir and the repurposed drugs fluoxetine and itraconazole effectively impairs SARS‐CoV‐2 infection in vitro
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    The Function of the Hypothalamic–Pituitary–Adrenal Axis During Experimental Autoimmune Encephalomyelitis: Involvement of Oxidative Stress Mediators
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    IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3
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    Hepatoenteric recycling is a new disposition mechanism for orally administered phenolic drugs and phytochemicals in rats
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    Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis
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    Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit
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    Distribution of dietary protein intake in daily meals influences skeletal muscle hypertrophy via the muscle clock
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    Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo
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    Transcriptional analysis of mouse wounds grafted with human mesenchymal stem cells and platelets
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    A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation
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    Brain endothelial PTEN/AKT/NEDD4-2/MFSD2A axis regulates blood-brain barrier permeability
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    A Neural Circuit Mechanism Controlling Breathing by Leptin in the Nucleus Tractus Solitarii
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    Reduction in Hindquarter Vascular Resistance Supports 5-HT7 Receptor Mediated Hypotension
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    T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1
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    Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption
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    Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence
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  95. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.15494

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  96. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    l-α-aminoadipate causes astrocyte pathology with negative impact on mouse hippocampal synaptic plasticity and memory
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      DOI: 10.1096/fj.202100336R

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    AMPA induced cognitive impairment in rats: Establishing the role of endoplasmic reticulum stress inhibitor, 4-PBA
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    CGRP induces migraine-like symptoms in mice during both the active and inactive phases
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    Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis
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    Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions
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    Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction
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      DOI: 10.7554/eLife.62927

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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.18632/oncotarget.27989

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    Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways
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    Development of red genetically encoded biosensor for visualization of intracellular glucose dynamics
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    PPP2R4 dysfunction promotes KRAS-mutant lung adenocarcinoma development and mediates opposite responses to MEK and mTOR inhibition
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  108. Jun 2021
  109. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Schwann cell precursors generate sympathoadrenal system during zebrafish development
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    The voltage-gated proton channel Hv1 promotes microglia-astrocyte communication and neuropathic pain after peripheral nerve injury
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    UNC-2 CaV2 channel localization at presynaptic active zones depends on UNC-10/RIM and SYD-2/Liprin-α in Caenorhabditis elegans
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      DOI: 10.1523/JNEUROSCI.0076-21.2021

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  112. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin.
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  113. mcr.aacrjournals.org mcr.aacrjournals.org
    Development and Characterization of Novel Endoxifen-Resistant Breast Cancer Cell Lines Highlight Numerous Differences from Tamoxifen-Resistant Models
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    Development and Validation of a Novel Nomogram for Individualized Prediction of Survival in Cancer of Unknown Primary
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    Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
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  116. cancerres.aacrjournals.org cancerres.aacrjournals.org
    STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer
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    A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma
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      DOI: 10.7554/eLife.65234

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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrinsic OXPHOS limitations underlie cellular bioenergetics in leukemia
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    Bioreactor Suspension Culture: Differentiation and Production of Cardiomyocyte Spheroids From Human Induced Pluripotent Stem Cells
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    Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2
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    The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression
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    Multi-Platform Metabolomics Analyses Revealed the Complexity of Serum Metabolites in LPS-Induced Neuroinflammed Rats Treated with Clinacanthus nutans Aqueous Extract
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    Activation of nuclear receptor PXR induces atherogenic lipids and PCSK9 through SREBP2‐mediated mechanism
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    Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity
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    Structural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein
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    The metabolite 5-methyl-1,3-benzenediol and its derivative methyl-2,4-dihydroxy-6-methylbenzoate from the lichen Parmotrema tinctorum with potent apoptotic and anti-angiogenesis effects
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    Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma
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    Role of Satb1 and Satb2 Transcription Factors in the Glutamate Receptors Expression and Ca2+ Signaling in the Cortical Neurons In Vitro
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  160. elifesciences.org elifesciences.org
    Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis
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      DOI: 10.7554/eLife.58342

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  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid
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      DOI: 10.7554/eLife.67315

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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors
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      DOI: 10.7554/eLife.63668

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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine regulates ovarian cancer cell migration and invasion through ETS1
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      DOI: 10.1016/j.heliyon.2021.e07064

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  164. www.embopress.org www.embopress.org
    Gut microbiota-CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten-induced enteropathy
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      DOI: 10.15252/emmm.202114059

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  165. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene
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      DOI: 10.1002/jnr.24905

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  166. link.springer.com link.springer.com
    Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription
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      DOI: 10.1186/s13072-021-00403-w

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  167. www.sciencedirect.com www.sciencedirect.com
    A diverse collection of B cells responded to HIV infection in infant BG505
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      DOI: 10.1016/j.xcrm.2021.100314

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    Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK
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      DOI: 10.1016/j.neuron.2021.05.023

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    Tumor vessel co-option probed by single-cell analysis
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      DOI: 10.1016/j.celrep.2021.109253

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    The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation
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      DOI: 10.1016/j.celrep.2021.109252

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    SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network
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      DOI: 10.1016/j.celrep.2021.109259

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    Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening
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    VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells
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      DOI: 10.1016/j.celrep.2021.109255

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    Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior
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      DOI: 10.1016/j.celrep.2021.109266

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    ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation
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      DOI: 10.1016/j.stem.2021.05.013

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    Identification and validation of selective deubiquitinase inhibitors
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      DOI: 10.1016/j.chembiol.2021.05.012

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    Antibiotic-induced disruption of the microbiome exacerbates chemotherapy-induced diarrhoea and can be mitigated with autologous faecal microbiota transplantation
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      DOI: 10.1016/j.ejca.2021.05.015

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    sciencedirect.com/science/article/pii/S0959804921003233
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    B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV
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      DOI: 10.1016/j.cell.2021.04.032

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    sciencedirect.com/science/article/pii/S0092867421005353
  179. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    High‐Throughput Screening of Compound Neurotoxicity Using 3D‐Cultured Neural Stem Cells on a 384‐Pillar Plate
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      DOI: 10.1002/cpz1.107

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  180. elifesciences.org elifesciences.org
    Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis
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      DOI: 10.7554/eLife.62196

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  181. elifesciences.org elifesciences.org
    Voltage-clamp fluorometry analysis of structural rearrangements of ATP-gated channel P2X2 upon hyperpolarization
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      DOI: 10.7554/eLife.65822

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  182. elifesciences.org elifesciences.org
    Somatostatin-expressing parafacial neurons are CO2/H+ sensitive and regulate baseline breathing
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      DOI: 10.7554/eLife.60317

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  183. www.nature.com www.nature.com
    TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice
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      DOI: 10.1038/s41467-021-23735-3

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    nature.com/articles/s41467-021-23735-3
  184. www.sciencedirect.com www.sciencedirect.com
    C. elegans survival assays to discern global and transcription-coupled nucleotide excision repair
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      DOI: 10.1016/j.xpro.2021.100586

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    Defining corneal chemical burns: A novel exact and adjustable ocular model
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      DOI: 10.1016/j.toxrep.2021.06.005

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  186. elifesciences.org elifesciences.org
    Wnt- and glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division
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      DOI: 10.7554/eLife.59791

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  187. elifesciences.org elifesciences.org
    Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta
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      DOI: 10.7554/eLife.63488

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