1,305 Matching Annotations
  1. Jun 2022
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance
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    ncbi.nlm.nih.gov/pmc/articles/PMC9186388/
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    Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation
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    sciencedirect.com/science/article/pii/S1097276522004865
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    Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9189020/
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    A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency
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    sciencedirect.com/science/article/pii/S2211124722007100
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    Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity
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    science.org/doi/full/10.1126/sciadv.abl5032
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9132451/
  8. May 2022
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC9130554/
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    UPF1 promotes rapid degradation of m6A-containing RNAs
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    sciencedirect.com/science/article/pii/S2211124722006349
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    DDX41 is required for cGAS-STING activation against DNA virus infection
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    sciencedirect.com/science/article/pii/S2211124722006295
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    XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
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    sciencedirect.com/science/article/pii/S0092867422005323
  13. aacrjournals.org aacrjournals.org
    Increased microtubule growth triggered by microvesicle-mediated paracrine signaling is required for melanoma cancer cell invasion
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    aacrjournals.org/cancerrescommun/article/2/5/366/698979/Increased-Microtubule-Growth-Triggered-by
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrinsically disordered regions couple the ligand binding and kinase activation of Trk neurotrophin receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9117555/
  15. www.researchsquare.com www.researchsquare.com
    Home
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    researchsquare.com/article/rs-7072571/'https://www.researchsquare.com/article/rs-7072571/v1
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    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
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    sciencedirect.com/science/article/pii/S0092867422005268
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    CDX2-induced intestinal metaplasia in human gastric organoids derived from induced pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2589004222005855
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    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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    sciencedirect.com/science/article/pii/S1097276522003264
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysfunction of Inflammatory Pathways and Their Relationship With Psychological Factors in Adult Female Patients With Eating Disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC9062031/
  20. www.nature.com www.nature.com
    Convergent somatic mutations in metabolism genes in chronic liver disease
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    nature.com/articles/s41586-021-03974-6
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    Loss of PRMT7 reprograms glycine metabolism to selectively eradicate leukemia stem cells in CML
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    sciencedirect.com/science/article/pii/S1550413122001310
  22. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8563373/
  24. Apr 2022
  25. www.sciencedirect.com www.sciencedirect.com
    PIIS2589004222005594-html.html
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    sciencedirect.com/science/article/pii/S2589004222005594
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    Adeno-associated-virus-mediated gene delivery to ovaries restores fertility in congenital infertile mice
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    sciencedirect.com/science/article/pii/S2666379122001239
  27. link.springer.com link.springer.com
    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
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    link.springer.com/article/10.1007/s11010-022-04433-0
  28. aacrjournals.org aacrjournals.org
    Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models
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    aacrjournals.org/mct/article/20/12/2352/675163/Rational-Combination-of-CRM1-Inhibitor-Selinexor
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    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
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    sciencedirect.com/science/article/pii/S1097276522002696
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    DNA replication is highly resilient and persistent under the challenge of mild replication stress
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    sciencedirect.com/science/article/pii/S2211124722004594
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    Glutamatergic synapses from the insular cortex to the basolateral amygdala encode observational pain
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    sciencedirect.com/science/article/pii/S0896627322002665
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Foxo1-Klf2-S1pr1-Gnai1-Rac1 signaling axis is a critical mediator of Ostm1 regulatory network in T-lymphopoiesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9010627/
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    Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial
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    sciencedirect.com/science/article/pii/S1550413122000948
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs
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    ncbi.nlm.nih.gov/pmc/articles/PMC9005190/
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    Rapid establishment of human colonic organoid knockout lines
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    sciencedirect.com/science/article/pii/S2666166722001885
  36. www.sciencedirect.com www.sciencedirect.com
    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    sciencedirect.com/science/article/pii/S2211124722003886
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    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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    sciencedirect.com/science/article/pii/S2211124722003199
  38. www.sciencedirect.com www.sciencedirect.com
    Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C
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    sciencedirect.com/science/article/pii/S1074761322001327
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIRO2 regulates prostate cancer cell growth via GCN1-dependent stress signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8983529/
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    Carbamazepine promotes surface expression of mutant Kir6.2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy
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    sciencedirect.com/science/article/pii/S0021925822003441
  41. academic.oup.com academic.oup.com
    Inflammasome activation and pyroptosis via a lipid-regulated SIRT1-p53-ASC axis in macrophages from male mice and humans
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    academic.oup.com/endo/article/163/4/bqac014/6523230
  42. aacrjournals.org aacrjournals.org
    δ-Tocotrienol is the most potent vitamin E form in inhibiting prostate cancer cell growth and inhibits prostate carcinogenesis in Ptenp-/- mice
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    aacrjournals.org/cancerpreventionresearch/article/15/4/233/682296/Tocotrienol-is-the-Most-Potent-Vitamin-E-Form-in
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual signaling via interferon and DNA damage response elicits entrapment by giant PML nuclear bodies
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    ncbi.nlm.nih.gov/pmc/articles/PMC8975554/
  44. Mar 2022
  45. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14558
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acute inflammation down-regulates alpha-synuclein expression in enteric neurons
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14656
  47. www.sciencedirect.com www.sciencedirect.com
    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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    sciencedirect.com/science/article/pii/S2211124722003278
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14666
  49. www.embopress.org www.embopress.org
    Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission
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    embopress.org/doi/abs/10.15252/embj.2021109352
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions
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    ncbi.nlm.nih.gov/pmc/articles/PMC8933006/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Population genomics reveals that natural variation in PRDM16 contributes to cold tolerance in domestic cattle
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    ncbi.nlm.nih.gov/pmc/articles/PMC8920848/
  52. link.springer.com link.springer.com
    Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury
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    link.springer.com/article/10.1186/s12974-022-02427-9
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ghrelin Regulates Expression of the Transcription Factor Pax6 in Hypoxic Brain Progenitor Cells and Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC8909042/
  54. www.sciencedirect.com www.sciencedirect.com
    Central dopaminergic control of cell proliferation in the colonic epithelium
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    sciencedirect.com/science/article/pii/S0168010222000736
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reducing host aldose reductase activity promotes neuronal differentiation of transplanted neural stem cells at spinal cord injury sites and facilitates locomotion recovery
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    ncbi.nlm.nih.gov/pmc/articles/PMC8820702/
  56. www.sciencedirect.com www.sciencedirect.com
    Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord
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    sciencedirect.com/science/article/pii/S2211124722001474
  57. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Alzheimer’s disease and cerebrovascular pathology alter brain endothelial inward rectifier potassium (KIR2.1) channels
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15751
  58. Feb 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7611539/
  60. www.embopress.org www.embopress.org
    LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function
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    embopress.org/doi/abs/10.15252/embj.2021108119
  61. www.sciencedirect.com www.sciencedirect.com
    Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces
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    sciencedirect.com/science/article/pii/S1931312821005825
  62. www.sciencedirect.com www.sciencedirect.com
    Transgenerational inheritance of sexual attractiveness via small RNAs enhances evolvability in C. elegans
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    sciencedirect.com/science/article/pii/S1534580722000053
  63. www.sciencedirect.com www.sciencedirect.com
    Neuropeptide signaling and SKN-1 orchestrate differential responses of the proteostasis network to dissimilar proteotoxic insults
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    sciencedirect.com/science/article/pii/S2211124722000663
  64. www.sciencedirect.com www.sciencedirect.com
    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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    sciencedirect.com/science/article/pii/S1097276522000028
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33929
  66. link.springer.com link.springer.com
    Targeting CCR2+ macrophages with BET inhibitor overcomes adaptive resistance to anti-VEGF therapy in ovarian cancer
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    link.springer.com/article/10.1007/s00432-021-03885-z
  67. Jan 2022
  68. www.nature.com www.nature.com
    Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes
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    nature.com/articles/s41596-021-00638-7
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses
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    ncbi.nlm.nih.gov/pmc/articles/PMC8752090/
  70. www.sciencedirect.com www.sciencedirect.com
    NHR-80 senses the mitochondrial UPR to rewire citrate metabolism for lipid accumulation in Caenorhabditis elegans
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    sciencedirect.com/science/article/pii/S2211124721017101
  71. www.sciencedirect.com www.sciencedirect.com
    Sphingosine 1-phosphate receptor 4 promotes nonalcoholic steatohepatitis by activating NLRP3 inflammasome
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    sciencedirect.com/science/article/pii/S2352345X21002526
  72. www.sciencedirect.com www.sciencedirect.com
    Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity
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    sciencedirect.com/science/article/pii/S2589004221015911
  73. www.sciencedirect.com www.sciencedirect.com
    The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2
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    sciencedirect.com/science/article/pii/S2589004221016734
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFBR3L is an inhibin B co-receptor that regulates female fertility
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    ncbi.nlm.nih.gov/pmc/articles/PMC8673766/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8673768/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defects in Emerin-nucleoskeleton binding disrupt nuclear structure and promote breast cancer cell motility and metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8254762/
  77. Dec 2021
  78. www.science.org www.science.org
    Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
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    science.org/doi/abs/10.1126/sciadv.abl4988
  79. www.science.org www.science.org
    TGFBR3L is an inhibin B co-receptor that regulates female fertility
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    science.org/doi/10.1126/sciadv.abl4391
  80. www.sciencedirect.com www.sciencedirect.com
    Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells
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    sciencedirect.com/science/article/pii/S2589004221016230
  81. www.sciencedirect.com www.sciencedirect.com
    Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling
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    sciencedirect.com/science/article/pii/S2589004221015777
  82. www.sciencedirect.com www.sciencedirect.com
    Kaposi’s sarcoma herpesvirus activates the hypoxia response to usurp HIF2α-dependent translation initiation for replication and oncogenesis
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    sciencedirect.com/science/article/pii/S2211124721016405
  83. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002031RR
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    Dynamic stem cell selection safeguards the genomic integrity of the epidermis
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    sciencedirect.com/science/article/pii/S1534580721009424
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8660019/
  86. www.sciencedirect.com www.sciencedirect.com
    YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis
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    sciencedirect.com/science/article/pii/S2211124721016041
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    lncRNA BORG:TRIM28 Complexes Drive Metastatic Progression by Inducing α6 Integrin/CD49f Expression in Breast Cancer Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8642309/
  88. elifesciences.org elifesciences.org
    Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology
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    elifesciences.org/articles/73430
  89. www.sciencedirect.com www.sciencedirect.com
    Methods to separate nuclear soluble fractions reflecting localizations in living cells
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    sciencedirect.com/science/article/pii/S2589004221014747
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recombinant human GLP-1 beinaglutide regulates lipid metabolism of adipose tissues in diet-induced obese mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8605346/
  91. www.sciencedirect.com www.sciencedirect.com
    CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
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    sciencedirect.com/science/article/pii/S2211124721015461
  92. Nov 2021
  93. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Susceptibility rhythm to bacterial endotoxin in myeloid clock-knockout mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8598165/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysfunctional TRPM8 signalling in the vascular response to environmental cold in ageing
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