1,432 Matching Annotations
  1. Jun 2023
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    MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S1535610823001824
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    KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC9735414/
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    LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL
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    dx.doi.org/10.1158/2159-8290.CD-22-0376
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    APOE expression and secretion are modulated by mitochondrial dysfunction
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    ncbi.nlm.nih.gov/pmc/articles/PMC10231934/
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    Endonuclease VIII-like 1 deficiency potentiates nigrostriatal dopaminergic neuron degeneration in a male mouse model of Parkinson's disease
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15794
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    PICT-1 regulates p53 splicing and sensitivity of medullary thyroid carcinoma cells to Everolimus
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    onlinelibrary.wiley.com/doi/10.1111/jne.13187
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16093
  9. May 2023
  10. 52.53.155.43 52.53.155.43
    Efficient self-organization of blastoids solely from mouse ESCs is facilitated by transient reactivation of 2C gene network
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    52.53.155.43/d6c42894cd1d74c54111e2279a70a7e2e2f22de0/2023.04.12.536583v1.full-html.html
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    ADAR1-mediated RNA editing promotes B cell lymphomagenesis
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    sciencedirect.com/science/article/pii/S2589004223009410
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16087
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    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
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    sciencedirect.com/science/article/pii/S2211124723004904
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    Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC10524732/
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    Thyroid Stem Cell Speciation – A Major Role for PKC
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    academic.oup.com/endo/article/164/6/bqad067/7147332
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    Relationships between gene expression and behavior in mice in response to systemic modulation of the O-GlcNAcylation pathway
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    52.53.155.43/91708249814bb69a32598df046fda7e66eaa9543/Journal of Neurochemistry - 2023 - Bell - Relationships between gene expression and behavior in mice in response to-html.html
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    eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content
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    embopress.org/doi/10.15252/embj.2022112362
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    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses
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    BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides
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    ncbi.nlm.nih.gov/pmc/articles/PMC10161466/
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    Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo
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    N-myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination
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    onlinelibrary.wiley.com/doi/full/10.1002/glia.24108
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    Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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  26. Apr 2023
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    Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex
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    IFITM3 blocks influenza virus entry by sorting lipids and stabilizing hemifusion
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    Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication
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    Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
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    nature.com/articles/s41467-023-37617-3
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    Buffering of transcription rate by mRNA half-life is a conserved feature of Rett syndrome models
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    The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage
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  33. Mar 2023
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    Altered striatal actin dynamics drives behavioral inflexibility in a mouse model of fragile X syndrome
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    A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature
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    Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutating novel interaction sites in NRP1 reduces SARS-CoV-2 spike protein internalization
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    ncbi.nlm.nih.gov/pmc/articles/PMC9957656/
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    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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    Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats
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    mdpi.com/2218-273X/13/3/516
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    Minimal upstream open reading frame of Per2 mediates phase fitness of the circadian clock to day/night physiological body temperature rhythm
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    Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer
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    Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9975292/
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    Psychological stress induces an increase in cholinergic enteric neuromuscular pathways mediated by glucocorticoid receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9971731/
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    Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity
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  45. Feb 2023
  46. academic.oup.com academic.oup.com
    Genetic Val66Met BDNF Variant Increases Hyperphagia on Fat-rich Diets in Mice
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    academic.oup.com/endo/article/164/3/bqad008/6984997
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    Prostaglandins limit nuclear actin to control nucleolar function during oogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9981675/
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    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9528501/
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    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
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    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
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    Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis
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  54. Jan 2023
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    Elevated PAF1-RAD52 axis confers chemoresistance to human cancers
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    FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration
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    A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3
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  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ADAR RNA editing on antisense RNAs results in apparent U-to-C base changes on overlapping sense transcripts
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    ncbi.nlm.nih.gov/pmc/articles/PMC9852825/
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    Gasdermin D pore-forming activity is redox-sensitive
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    Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in the enteric nervous system
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    Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model
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    Autotaxin facilitates selective LPA receptor signaling
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    Transient neurogenesis in ischemic cortex from Sox2+... : Neural Regeneration Research
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    Postnatal neuronal Bace1 deletion impairs neuroblast and oligodendrocyte maturation
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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddac282/6825270
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    Development of CAR-T cells specifically targeting cancer stem cell antigen DNAJB8 against solid tumours
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    ncbi.nlm.nih.gov/pmc/articles/PMC9977765/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
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    Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
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    Remarkable Synergy When Combining EZH2 Inhibitors with YM155 Is H3K27me3-Independent
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  70. Dec 2022
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-lasting BDNF signaling alterations in the amygdala of adolescent female rats exposed to the activity-based anorexia model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9772010/
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    Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality
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    ncbi.nlm.nih.gov/pmc/articles/PMC9793319/
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    Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice
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    Increased replication origin firing links replication stress to whole chromosomal instability in human cancer
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    The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response
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    VLDL-VLDLR axis facilitates brown fat thermogenesis through replenishment of lipid fuels and PPARβ/δ activation
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    Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
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    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
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    Exosomal miR-23b from bone marrow mesenchymal stem cells alleviates oxidative stress and pyroptosis after intracerebral hemorrhage
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    PERIOD 2 Regulates Low Dose Radioprotection via PER2/pGSK3β/β-Catenin/Per2 Loop
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    ncbi.nlm.nih.gov/pmc/articles/PMC9708791/
  81. Nov 2022
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    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2
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    Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells
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    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
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    CRABP2 is associated with thyroid cancer recurrence and promotes invasion via the integrin/FAK/AKT pathway
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    academic.oup.com/endo/article-abstract/163/12/bqac171/6761323
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    The Mitochondrial RNA Granule Modulates Manganese-Dependent Cell Toxicity
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    AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity
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    CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation
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    The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool
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    FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism
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    NEIL3 contributes to the Fanconi anemia/BRCA pathway by promoting the downstream double-strand break repair step
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    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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  193. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  194. Feb 2022
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  196. www.embopress.org www.embopress.org
    LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function
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    Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces
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    Transgenerational inheritance of sexual attractiveness via small RNAs enhances evolvability in C. elegans
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    Neuropeptide signaling and SKN-1 orchestrate differential responses of the proteostasis network to dissimilar proteotoxic insults
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    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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    Targeting CCR2+ macrophages with BET inhibitor overcomes adaptive resistance to anti-VEGF therapy in ovarian cancer
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  203. Jan 2022
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    Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses
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    NHR-80 senses the mitochondrial UPR to rewire citrate metabolism for lipid accumulation in Caenorhabditis elegans
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    Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity
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    The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2
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