1,159 Matching Annotations
  1. Jun 2024
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    Longitudinal humoral analysis in RSV-infected infants identifies pre-existing RSV strain-specific G and evolving cross-reactive F antibodies
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    sciencedirect.com/science/article/pii/S1074761324002723
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    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148061/
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    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
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    sciencedirect.com/science/article/pii/S2666379124002842
  5. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
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    molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
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    Potentially functional genetic variants in interferon regulatory factor family genes are associated with colorectal cancer survival
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23752
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    Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
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    sciencedirect.com/science/article/pii/S1534580724003277
  8. May 2024
  9. 52.53.155.43 52.53.155.43
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    Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer’s disease
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    link.springer.com/article/10.1186/s13024-024-00725-9
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    TUDCA alleviates atherosclerosis by inhibiting AIM2 inflammasome and enhancing cholesterol efflux capacity in macrophage
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    ncbi.nlm.nih.gov/pmc/articles/PMC11112614/
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    IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility
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    sciencedirect.com/science/article/pii/S2211124721002059
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
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    sciencedirect.com/science/article/pii/S1074761324002309
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    Development of nitroalkene-based inhibitors to target STING-dependent inflammation
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    sciencedirect.com/science/article/pii/S2213231724001800
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    Pathways for macrophage uptake of cell-free circular RNAs
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13659
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    Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers
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    Lenvatinib-resistant hepatocellular carcinoma promotes malignant potential of tumor-associated macrophages via exosomal miR-301a-3p
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    onlinelibrary.wiley.com/doi/10.1002/ags3.12814
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    Bioengineering scalable and drug-responsive in vitro human multicellular non-alcoholic fatty liver disease microtissues encapsulated in the liver extracellular matrix-derived hydrogel
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089098/
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    Atherosis-associated lnc_000048 activates PKR to enhance STAT1-mediated polarization of THP-1 macrophages to M1 phenotype
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    ncbi.nlm.nih.gov/pmc/articles/PMC11090429/
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    Intratumoral delivery of the chitin-derived C100 adjuvant promotes robust STING, IFNAR, and CD8+ T cell-dependent anti-tumor immunity
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    N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation
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    Multiple ubiquitin ligases protect human genome integrity by targeting cancer-associated APOBEC3 deaminases for degradation
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    biorxiv.org/content/10.1101/2024.04.23.590688v1
  25. Apr 2024
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    Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia
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    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
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    sciencedirect.com/science/article/pii/S1535610824001284
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    ISGylation by HERCs facilitates STING activation
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    NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks
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    Macrophage-coated tumor cluster aggravates hepatoma invasion and immunotherapy resistance via generating local immune deprivation
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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11000015/
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    Enhanced plant-derived vesicles for nucleotide delivery for cancer therapy
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  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation
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    Acquired immune resistance is associated with interferon signature and modulation of KLF6/c-MYB transcription factors in myeloid leukemia
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    onlinelibrary.wiley.com/doi/10.1002/eji.202350717
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    P. gingivalis-Induced TLR2 Interactome Analysis Reveals Association with PARP9
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    journals.sagepub.com/doi/10.1177/00220345231222181
  36. Mar 2024
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    Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry
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    ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition
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    Vaccination with staphylococcal protein A protects mice against systemic complications of skin infection recurrences
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    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
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    ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
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    MAPK14 as a key gene for regulating inflammatory response and macrophage M1 polarization induced by ferroptotic keratinocyte in psoriasis
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    link.springer.com/article/10.1007/s10753-024-01994-8
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  44. Feb 2024
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    Inhibition of G protein-coupled receptor 68 using homoharringtonine attenuates chronic kidney disease-associated cardiac impairment
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    sciencedirect.com/science/article/pii/S193152442400032X
  46. 52.53.155.43 52.53.155.43
    Identification of high-performing antibodies for tyrosine-protein kinase SYK for use in Western Blot, immunoprecipitation and immunofluorescence
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    Cav3.1 T-type calcium channel blocker NNC 55-0396 reduces atherosclerosis by increasing cholesterol efflux
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    sciencedirect.com/science/article/pii/S0006295224000790
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13614
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    The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation
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    SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells
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    Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity
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    Effector functions are required for broad and potent protection of neonatal mice with antibodies targeting HSV glycoprotein D
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    SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐PD‐1 immunotherapy in head and neck cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10850803/
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    Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer
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    biorxiv.org/content/10.1101/2023.12.12.571247v1
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    Antiviral response and HIV-1 inhibition in sickle cell disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10839265/
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    Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth
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    biorxiv.org/content/10.1101/2023.10.05.561003v1
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Borrelia-specific antibody profiles and joint fluid antibody-dependent complement deposition distinguish antibiotic-refractory from antibiotic-responsive Lyme arthritis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10830897/
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    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524644/
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    Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M
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    ncbi.nlm.nih.gov/pmc/articles/PMC10829726/
  62. Jan 2024
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13584
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    The predictive value of BTG1 for the response of newly diagnosed acute myeloid leukemia to decitabine
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802042/
  65. 52.53.155.43 52.53.155.43
    A guide to selecting high-performing antibodies for PLC-gamma-2 for use in Western Blot, immunoprecipitation and immunofluorescence
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    Targeting cell-type-specific, choroid-peripheral immune signaling to treat age-related macular degeneration
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    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10793589/
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    Selective Impact of Selenium Compounds on Two Cytokine Storm Players
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    Fish oil supplementation modifies the proteome, lipidome and function of high-density lipoprotein: Findings from a trial in young healthy adults
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    sciencedirect.com/science/article/pii/S0022316624000269
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    SUMOylated IL-33 in the nucleus stabilizes the transcription factor IRF1 in hepatocellular carcinoma cells to promote immune escape
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    science.org/doi/10.1126/scisignal.abq3362
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    Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7
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    ncbi.nlm.nih.gov/pmc/articles/PMC10772347/
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    Direct translation of incoming retroviral genomes
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    Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system
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    sciencedirect.com/science/article/pii/S2451945623004361
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    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
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  76. Dec 2023
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    Human inherited CCR2 deficiency underlies progressive polycystic lung disease
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    Aedes aegypti saliva modulates inflammasome activation and facilitates flavivirus infection in vitro
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    A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs
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    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    Anti-inflammatory mechanisms in cancer research: Characterization of a distinct M2-like macrophage model derived from the THP-1 cell line
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    Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis
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    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
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    Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia
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    Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10715669/
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    MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells
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  87. Nov 2023
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    Airway epithelial cells and macrophages trigger IL-6-CD95/CD95L axis and mediate initial immunopathology of COVID-19
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    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions
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    embopress.org/doi/10.15252/embj.2023114221
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    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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    Design and synthesis of bioreductive prodrugs of class I histone deacetylase inhibitors and their biological evaluation in virally transfected acute myeloid leukemia cells
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    onlinelibrary.wiley.com/doi/10.1002/ardp.202300536
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    Effect of Flavonoids on MCP-1 Expression in Human Coronary Artery Endothelial Cells and Impact on MCP-1-Dependent Migration of Human Monocytes
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    Anti–PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases
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  190. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Enolase-1 Antibody Targets Multiple Interacting Players in the Tumor Microenvironment of Advanced Prostate Cancer
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  194. www.sciencedirect.com www.sciencedirect.com
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  196. Dec 2022
  197. www.embopress.org www.embopress.org
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    embopress.org/doi/10.15252/embj.2022111961
  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  199. www.science.org www.science.org
    Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination
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  200. www.sciencedirect.com www.sciencedirect.com
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    Danger signals released during cold ischemia storage activate NLRP3 inflammasome in myeloid cells and influence early allograft function in liver transplantation
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  204. www.sciencedirect.com www.sciencedirect.com
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  205. Nov 2022
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    LPA maintains innate antiviral immunity in a pro-active state via STK38L-mediated IRF3 Ser303 phosphorylation
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  207. 52.53.155.43 52.53.155.43
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  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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