1,317 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124724011021
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    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11378723/
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    Using microfluidic and conventional platforms to evaluate the effects of lanthanides on spheroid formation
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    sciencedirect.com/science/article/pii/S0300483X24002129
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    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2451945624003234
  7. Aug 2024
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    Confinement controls the directional cell responses to fluid forces
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    sciencedirect.com/science/article/pii/S221112472401043X
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Normalization of Snai1-mediated vessel dysfunction increases drug response in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347376/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Platelet Angiopoietin-1 Protects Against Murine Models of Tumor Metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335083/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetalax (Oxyphenisatin acetate, NSC 59687) and bisacodyl Cause Oncosis in Triple Negative Breast Cancer Cell lines by Poisoning Ion Exchange Membrane Protein TRPM4
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    ncbi.nlm.nih.gov/pmc/articles/PMC11322923/
  12. spj.science.org spj.science.org
    Intermittent F-actin Perturbations by Magnetic Fields Inhibit Breast Cancer Metastasis
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    spj.science.org/doi/10.34133/research.0080
  13. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    cell.com/cell/fulltext/S0092-8674(20)30163-X
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    Adipocytes promote metastasis of breast cancer by attenuating the FOXO1 effects and regulating copper homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320833/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11311709/
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    Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role
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    sciencedirect.com/science/article/pii/S1097276524006233
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    Enhanced expression of galectin-9 in triple negative breast cancer cells following radiotherapy: Implications for targeted therapy
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35107
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292198/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
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    Nuclear transport proteins are secreted by cancer cells and identified as potential novel cancer biomarkers
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.33832
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    Naive primary neutrophils play a dual role in the tumor microenvironment
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    sciencedirect.com/science/article/pii/S2589004224018571
  22. www.cell.com www.cell.com
    A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
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    cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00273-3
  23. www.cell.com www.cell.com
    ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines
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    cell.com/cell-reports/fulltext/S2211-1247(24)00762-9
  24. transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com
    iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer
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    transmedcomms.biomedcentral.com/articles/10.1186/s41231-024-00161-3
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    Revealing the tumor suppressive sequence within KL1 domain of the hormone Klotho
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    nature.com/articles/s41388-023-02904-2
  26. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Horie-html.html
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    Effects of Juglone and Curcumin Administration on Expression of FABP5 and FABP9 in MCF-7 and MDA-MB-231 Breast Cancer Cell Lines
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    link.springer.com/article/10.1134/s199074782310001x
  28. www.embopress.org www.embopress.org
    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
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    embopress.org/doi/full/10.15252/emmm.202012716
  29. www.cell.com www.cell.com
    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30827-3
  30. www.cell.com www.cell.com
    Nuclear Deformation Causes DNA Damage by Increasing Replication Stress
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    cell.com/current-biology/fulltext/S0960-9822(20)31748-6
  31. www.mdpi.com www.mdpi.com
    Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile
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    mdpi.com/1420-3049/26/4/794/htm
  32. Jul 2024
  33. www.biorxiv.org www.biorxiv.org
    The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
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    biorxiv.org/content/10.1101/2024.07.22.604482v1
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    Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
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    sciencedirect.com/science/article/pii/S2211124724008611
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    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
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    sciencedirect.com/science/article/pii/S1097276524004799
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    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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    Reversion of pathogenic BRCA1 L1780P mutation confers resistance to PARP and ATM inhibitor in breast cancer
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    sciencedirect.com/science/article/pii/S2589004224016948
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    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
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    sciencedirect.com/science/article/pii/S0092867424006524
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    Affimer reagents enable targeted delivery of therapeutic agents and RNA via Virus-Like Particles
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    Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
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    Aberrant activation of AXL may drive progression of squamous cell carcinoma in CLL patients: a mechanistic study with clinical implications
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    nature.com/articles/s41416-024-02752-1
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a novel hybrid coumarin-hydroxamate conjugate targeting the HDAC1-Sp1-FOSL2 signaling axis for breast cancer therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11247895/
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    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
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    sciencedirect.com/science/article/pii/S2211124724008398
  45. www.biorxiv.org www.biorxiv.org
    Osmotic Stress Influences Microtubule Drug Response Via WNK1 Kinase Signaling
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    biorxiv.org/content/10.1101/2024.07.08.602030v1
  46. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224017255-main-html.html
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11238136/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NDRG1 acts as an oncogene in triple-negative breast cancer and its loss sensitizes cells to mitochondrial iron chelation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11231402/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11230627/
  51. link.springer.com link.springer.com
    Cellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis
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    link.springer.com/article/10.1007/s12195-024-00811-4
  52. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13675
  53. www.sciencedirect.com www.sciencedirect.com
    GRP78 inhibitor YUM70 upregulates 4E-BP1 and suppresses c-MYC expression and viability of oncogenic c-MYC tumors
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    sciencedirect.com/science/article/pii/S1476558624000629
  54. academic.oup.com academic.oup.com
    A RAD18–UBC13–PALB2–RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae563/7701480
  55. Jun 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology
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    ncbi.nlm.nih.gov/pmc/articles/PMC11193044/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A regulates DNA repair through chromatin organization and its deficiency triggers DNA damage-mediated anti-tumor immune response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11162808/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Double-modified, thio and methylene ATP analogue facilitates wound healing in vitro and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11161507/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRX4204 Induces Senescence and Cell Death in HER2-positive Breast Cancer and Synergizes with Anti-HER2 Therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11145169/
  60. www.biorxiv.org www.biorxiv.org
    Oxygen Sensor-Guided Fine Needle Biopsy Studies of Human Cancer Xenografts in Mice
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    biorxiv.org/content/10.1101/2024.05.27.596060v1
  61. May 2024
  62. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    sciencedirect.com/science/article/pii/S1535610824001697
  63. www.sciencedirect.com www.sciencedirect.com
    Adenovirus-mediated expression of MOAP-1, Bax and RASSF1A antagonizes chemo-drug resistance of human breast cancer cells expressing cancer stem cell markers
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    sciencedirect.com/science/article/pii/S0753332224006280
  64. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13667
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chloroquine-induced DNA damage synergizes with DNA repair inhibitors causing cancer cell death
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    ncbi.nlm.nih.gov/pmc/articles/PMC11128598/
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    LOXL2-mediated chromatin compaction is required to maintain the oncogenic properties of triple-negative breast cancer cells
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17112
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
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    sciencedirect.com/science/article/pii/S1074761324002309
  68. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    science.org/doi/10.1126/scisignal.adh4475
  69. www.biorxiv.org www.biorxiv.org
    Intracellular Retention of Estradiol is Augmented by GRAM Domain Containing Protein ASTER-B in Breast Cancer Cells
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    biorxiv.org/content/10.1101/2024.05.16.594581v1
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11097164/
  71. www.biorxiv.org www.biorxiv.org
    Activation of PKR by a short-hairpin RNA
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    biorxiv.org/content/10.1101/2024.05.08.592371v1
  72. www.sciencedirect.com www.sciencedirect.com
    Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants
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    sciencedirect.com/science/article/pii/S1097276524003277
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    Breast cancer-on-chip for patient-specific efficacy and safety testing of CAR-T cells
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    sciencedirect.com/science/article/pii/S1934590924001450
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resf1 is a compound G4 quadruplex-associated tumor suppressor for triple negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11081379/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small Extracellular Vesicles Promote Stiffness-mediated Metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11080964/
  76. journals.biologists.com journals.biologists.com
    Ferroptosis induces membrane blebbing in placental trophoblasts
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    journals.biologists.com/jcs/article/135/5/jcs255737/224124/Ferroptosis-induces-membrane-blebbing-in-placental
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    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    52.53.155.43/97841ca504d9556b3965877911b65905cd7f6735/2024.02.18.580900v1.full-html.html
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078187/
  79. www.science.org www.science.org
    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    science.org/doi/10.1126/sciadv.adj1468
  80. www.sciencedirect.com www.sciencedirect.com
    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    sciencedirect.com/science/article/pii/S2666379124002441
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    Ubiquitin-mediated regulation of APE2 protein abundance
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    sciencedirect.com/science/article/pii/S0021925824018386
  82. www.sciencedirect.com www.sciencedirect.com
    Targeted blocking of EGFR and GLUT1 by compound H reveals a new strategy for treatment of triple-negative breast cancer and nasopharyngeal carcinoma
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    sciencedirect.com/science/article/pii/S0928098724001003
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063688/
  84. link.springer.com link.springer.com
    A novel long non-coding RNA MIR4500HG003 promotes tumor metastasis through miR-483-3p-MMP9 axis in triple-negative breast cancer
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    link.springer.com/article/10.1038/s41419-024-06675-w
  85. Apr 2024
  86. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    sciencedirect.com/science/article/pii/S2211124724004911
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Class of Human ADAM8 Inhibitory Antibodies for Treatment of Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11054802/
  88. www.embopress.org www.embopress.org
    The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
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    embopress.org/doi/full/10.1038/s44321-024-00051-z
  89. rupress.org rupress.org
    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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    rupress.org/jcb/article/223/6/e202308013/276631/WW-domains-form-a-folded-type-of-nuclear
  90. link.springer.com link.springer.com
    Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines
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    link.springer.com/article/10.1186/s12885-024-12214-9
  91. www.embopress.org www.embopress.org
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  190. www.mdpi.com www.mdpi.com
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  191. www.sciencedirect.com www.sciencedirect.com
    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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  199. Sep 2023
  200. www.sciencedirect.com www.sciencedirect.com
    Selective Inhibition of indoleamine and tryptophan 2,3-dioxygenases: Comparative Study on Kynurenine Pathway in Cell Lines via LC-MS/MS-based Targeted Metabolomics
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    Activated platelets facilitate hematogenous metastasis of breast cancer by modulating the PDGFR-β/COX-2 axis
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  207. Aug 2023
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    LncRNA TYMSOS facilitates breast cancer metastasis and immune escape through downregulating ULBP3
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