4,894 Matching Annotations
  1. Jun 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification, Expression Profiling, Microbial Binding, and Agglutination Analyses of Two Cathepsin B Genes in Black Rockfish (Sebastes schlegelii)
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    pmc.ncbi.nlm.nih.gov/articles/PMC12112843/
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    Focal adhesion kinase promotes ribosome biogenesis to drive advanced thyroid cancer cell growth and survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC12127332/
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    Targeting the Glucose–Insulin Link in Head and Neck Squamous Cell Carcinoma Induces Cytotoxic Oxidative Stress and Inhibits Cancer Growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141995/
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    EGFRvIII-driven microenvironmental fibroblast activation and transformation accelerate oral cancer progression via lipocalin-2/STAT3 axis
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    sciencedirect.com/science/article/pii/S1476558625000739
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    Structures of butyrophilin multimers reveal a plier-like mechanism for Vγ9Vδ2 T cell receptor activation
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    sciencedirect.com/science/article/pii/S1074761325002328
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    Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
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    Merlin controls limb development and thumb formation by regulating primary cilium-hedgehog signaling
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    RNA m6A dynamics promote transcription and RNA stability of bivalent genes during iPSC-induced generation of human lung progenitors
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    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
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    Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy
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    The Prolonged Half-Life of the p53 Missense Variant R248Q Promotes Accumulation and Heterotetramer Formation with Wild-Type p53 to Exert the Dominant-Negative Effect
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    Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2
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    science.org/doi/10.1126/sciadv.adt2050
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    Cadherin-6 controls neuronal migration during mouse neocortical development via an integrin-mediated pathway
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70150
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    Phosphatase activity is dispensable for PRL-3-mediated oncogenesis and tumor progression
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    The design, manufacture and LNP formulation of mRNA for research use
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    link.springer.com/article/10.1038/s41596-025-01174-4
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    GPR45 modulates Gαs at primary cilia of the paraventricular hypothalamus to control food intake
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    The reaction mechanism for glycolysis side product degradation by Parkinson’s disease–linked DJ-1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12135873/
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    Structural basis of GluK2 kainate receptor activation by a partial agonist
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    Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant
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    Structural and functional basis of mechanosensitive TMEM63 channelopathies
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    Characterization of the N-terminal region of Crtac1B/LOTUS, an endogenous Nogo receptor-1 antagonist, required for secretion and soluble function
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    SARS-CoV-2 N protein exerts antitumor effects in NSCLC by inducing DNA damage and augmenting chemotherapeutic sensitivity
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    LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma
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    Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation
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    Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer
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    Mutant KRAS peptide targeted CAR-T cells engineered for cancer therapy
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    Glutamate transporter SLC1A6 promotes resistance to immunotherapy in cancer
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    Zmym2 Alters Expression of Key Craniofacial Genes
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    onlinelibrary.wiley.com/doi/10.1002/dvg.70018
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    Development of a chemically induced dissociation system via phage surface-displayed nanobody screening
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    Image-based identification and isolation of micronucleated cells to dissect cellular consequences
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  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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    Targeting IDH2 promotes antitumor immunity through epigenetic activation of cGAS-STING pathway
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    Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
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  41. May 2025
  42. www.sciencedirect.com www.sciencedirect.com
    Allogeneic CD19-targeted CAR-T therapy in refractory systemic lupus erythematosus achieved durable remission
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    sciencedirect.com/science/article/pii/S266663402500176X
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    Phase transition of WTAP regulates m6A modification of interferon-stimulated genes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12113268/
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    FEBS Press
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    Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells
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    nature.com/articles/s41592-025-02702-6
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    Cancer-associated loss-of-function mutations in KCNQ1 enhance Wnt/β-catenin signalling disrupting epithelial homeostasis
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    nature.com/articles/s41388-025-03447-4
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    Protocol to perform multiplexed assays of variant effect using curated loci prime editing
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    IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner
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    sciencedirect.com/science/article/pii/S193459092500181X
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    Mediator regulates transcriptional termination through crosstalk with pre-mRNA 3′ end processing factors
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    YTHDF1 differentiates the contributing roles of mTORC1 in aging
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    KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells
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    A lncRNA-mediated metabolic rewiring of cell senescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12187636/
  54. www.cell.com www.cell.com
    KSHV miRNAs target STING to evade innate immunity and facilitate KSHV lytic reactivation from latency
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    cell.com/cell-reports/fulltext/S2211-1247(25)00512-1
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    Machine-learning-assisted universal protein activation in living mice
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    NUDT21 lactylation reprograms alternative polyadenylation to promote cuproptosis resistance
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    nature.com/articles/s41421-025-00804-1
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    CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00221-6
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    Cross-species tropism of AAV.CPP.16 in the respiratory tract and its gene therapies against pulmonary fibrosis and viral infection
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    Constitutive ghrelin receptor activity enables reversal of dopamine D2 receptor signaling
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    Microbiota-derived urocanic acid triggered bytyrosine kinase inhibitors potentiates cancer immunotherapy efficacy
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    Cytoplasmic DIS3 is an exosome-independent endoribonuclease with catalytic activity toward circular RNAs
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    SFRS8 Regulates Memory by Modulating RNA Splicing of Synaptic Genes
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    E3 ubiquitin ligase RMND5A maintains the self-renewal state of human neural stem/precursor cells by regulating Wnt and mTOR signaling pathways
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70067
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    Alternative Splicing of FBLN2 Generates a Prometastatic Extracellular Matrix in Gastrointestinal Cancers by Determining N‐Glycosylation of Fibulin 2
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    The Combination of MIF Inhibitor and AEP Targeted Inhibitor to Reduce Lung Metastasis in Breast Cancer and Its Mechanism
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    A novel nonsense mutation of the glucocorticoid receptor gene causing glucocorticoid resistance with infertility
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    Metformin reverses 5-FU resistance induced by radiotherapy through mediating folate metabolism in colorectal cancer
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    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    Extreme multivalency and a composite short linear motif facilitate PCNA-binding, localisation and abundance of p21 (CDKN1A)
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    NECTIN4 regulates the cell surface expression of CD155 in non-small cell lung cancer cells and induces tumor resistance to PD-1 inhibitors
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    Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis
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    Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aeruginosa burden in mice
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    ATP-release pannexin channels are gated by lysophospholipids
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    Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortex
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    Division of labor among H3K4 methyltransferases defines distinct facets of homeostatic plasticity
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    Epigenetic Plasticity Drives Carcinogenesis and Multi-Therapy Resistance in Multiple Myeloma
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    ZAR1 and ZAR2 orchestrate the dynamics of maternal mRNA polyadenylation during mouse oocyte development
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    link.springer.com/article/10.1186/s13059-025-03593-8
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    Characterization of Gαs and Gαolf activation by catechol and non-catechol dopamine D1 receptor agonists
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    Estimating population immunity to SARS-CoV-2 by random sampling from primary and secondary healthcare in Scotland, May 2024
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    TOP1 Mutations and Cross-Resistance to Antibody–Drug Conjugates in Patients with Metastatic Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079096/
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    Genetic Screen in a Pre-Clinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities
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    Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration
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    Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1
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