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Mar 2025
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Genetic protection from type 1 diabetes resulting from accelerated insulin mRNA decay

1
1. scibot 20 Mar 2025
  
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  ATCCCat#: CRL-3216
  
  DOI: 10.1016/j.cell.2025.02.018
  
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sciencedirect.com/science/article/pii/S0092867425002065
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A microglia clonal inflammatory disorder in Alzheimer’s disease

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1. scibot 20 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.7554/eLife.96519
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11908784/
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A targeted MAVS fusion protein for controlled innate immune activation and antitumor therapy

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1. scibot 20 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1080/2162402X.2025.2478850
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11913393/
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Comprehensive discovery and functional characterization of the noncanonical proteome

1
1. scibot 20 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1038/s41422-024-01059-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11909191/
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Superior preclinical efficacy of co-treatment with BRG1/BRM and FLT3 inhibitor against AML cells with FLT3 mutations

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1. scibot 20 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1038/s41408-025-01251-7
  
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nature.com/articles/s41408-025-01251-7
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DAP12-associated synthetic antigen receptors enable multi-targeting of T cells with independent chimeric receptors in a small genetic payload

1
1. scibot 20 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.isci.2025.112142
  
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sciencedirect.com/science/article/pii/S258900422500402X
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PIF/harbinger transposon-derived protein promotes 7SL expression to enhance pathogen resistance

1
1. scibot 18 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1038/s44319-025-00379-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11893794/
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Protocol for the simultaneous activation and lentiviral transduction of primary human T cells with artificial T cell receptors

1
1. scibot 14 Mar 2025
  
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  American Type Culture Collection (ATCC)Cat# CRL-3216
  
  DOI: 10.1016/j.xpro.2025.103685
  
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sciencedirect.com/science/article/pii/S2666166725000917
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Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death

1
1. scibot 14 Mar 2025
  
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  ATCC # CRL-3216
  
  DOI: 10.1016/j.devcel.2025.02.012
  
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sciencedirect.com/science/article/pii/S1534580725001170
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Compact transcription factor cassettes generate functional, engraftable motor neurons by direct conversion

1
1. scibot 14 Mar 2025
  
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  ATCCCat#CRL-3216
  
  DOI: 10.1016/j.cels.2025.101206
  
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sciencedirect.com/science/article/pii/S2405471225000390
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Proteome-wide computational analyses reveal links between protein condensate formation and RNA biology

1
1. scibot 14 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1101/2025.03.03.640993
  
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biorxiv.org/content/10.1101/2025.03.03.640993v1
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Mitochondrial dysfunction drives a neuronal exhaustion phenotype in methylmalonic aciduria

1
1. scibot 13 Mar 2025
  
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  CRL-3216
  
  DOI: 10.1038/s42003-025-07828-z
  
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nature.com/articles/s42003-025-07828-z
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Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis

1
1. scibot 13 Mar 2025
  
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  ATCCCRL-3216
  
  DOI: 10.1016/j.celrep.2025.115399
  
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sciencedirect.com/science/article/pii/S2211124725001706
52.53.155.43 52.53.155.43

1-s2.0-S2589004225004316-main (1)-html.html

1
1. scibot 13 Mar 2025
  
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  CVCL_0063
  
  DOI: 10.24433/co.3851388.v1
  
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52.53.155.43/82b0d7e7b1f585d357ff23816b0095a55e83413f/1-s2.0-S2589004225004316-main (1)-html.html
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Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag

1
1. scibot 13 Mar 2025
  
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  CVCL_0063
  
  DOI: 10.1016/j.molcel.2025.02.012
  
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sciencedirect.com/science/article/pii/S1097276525001431
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TTC7A-ALK, a novel ALK fusion variant identified in a patient with metastatic lung adenocarcinoma, exhibits excellent response to crizotinib

1
1. scibot 11 Mar 2025
  
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  RRID: CVCL_0063
  
  DOI: 10.1016/j.tranon.2025.102345
  
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sciencedirect.com/science/article/pii/S1936523325000762
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Primary ciliary protein kinase A activity in the prefrontal cortex modulates stress in mice

1
1. scibot 11 Mar 2025
  
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  American Type Culture CollectionCat #CRL-3216
  
  DOI: 10.1016/j.neuron.2025.02.002
  
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sciencedirect.com/science/article/pii/S0896627325001151
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The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis

1
1. scibot 11 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.celrep.2025.115403
  
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sciencedirect.com/science/article/pii/S2211124725001743
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Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson’s disease

1
1. scibot 11 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.celrep.2025.115355
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12124131/
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Engineering mtDNA deletions by reconstituting end joining in human mitochondria

1
1. scibot 11 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.cell.2025.02.009
  
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sciencedirect.com/science/article/pii/S0092867425001941
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Recognition of MR1-antigen complexes by TCR Vγ9Vδ2

1
1. scibot 08 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.3389/fimmu.2025.1519128
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11876030/
www.cell.com www.cell.com

A family of bacterial Josephin-like deubiquitinases with an irreversible cleavage mode

1
1. scibot 07 Mar 2025
  
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  CRL-3216
  
  DOI: 10.1016/j.molcel.2025.02.002
  
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cell.com/molecular-cell/fulltext/S1097-2765(25)00107-8
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Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma

1
1. scibot 07 Mar 2025
  
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  CB_12022001
  
  DOI: 10.1016/j.cmet.2025.01.021
  
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cell.com/cell-metabolism/fulltext/S1550-4131(25)00021-X
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Metabolic engineering to facilitate anti-tumor immunity

1
1. scibot 07 Mar 2025
  
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  CRL-3216
  
  DOI: 10.1016/j.ccell.2025.02.004
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00056-X
aacrjournals.org aacrjournals.org

Blocking WNT7A Enhances MHC-I Antigen Presentation and Enhances the Effectiveness of Immune Checkpoint Blockade Therapy

1
1. scibot 06 Mar 2025
  
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  RRID: CVCL_0063
  
  DOI: 10.1158/2326-6066.CIR-24-0484
  
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aacrjournals.org/cancerimmunolres/article/13/3/400/752015/Blocking-WNT7A-Enhances-MHC-I-Antigen-Presentation
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A highland-adaptation variant near MCUR1 reduces its transcription and attenuates erythrogenesis in Tibetans

1
1. scibot 06 Mar 2025
  
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  CCTCCGDC0187
  
  DOI: 10.1016/j.xgen.2025.100782
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11960549/
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Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination

1
1. scibot 06 Mar 2025
  
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  ATCCCat#CRL-3216
  
  DOI: 10.1016/j.molcel.2025.02.007
  
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sciencedirect.com/science/article/pii/S1097276525001339
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VIPER-TACs leverage viral E3 ligases for disease-specific targeted protein degradation

1
1. scibot 06 Mar 2025
  
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  ATCCCat#CRL-3216
  
  DOI: 10.1016/j.chembiol.2025.02.002
  
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sciencedirect.com/science/article/pii/S2451945625000340
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Mitochondrial fusion and cristae reorganization facilitate acquisition of cardiomyocyte identity during reprogramming of murine fibroblasts

1
1. scibot 06 Mar 2025
  
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  ATCCCRL-3216
  
  DOI: 10.1016/j.celrep.2025.115377
  
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sciencedirect.com/science/article/pii/S2211124725001482
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TMEM41B is an endoplasmic reticulum Ca2+ release channel maintaining naive T cell quiescence and responsiveness

1
1. scibot 06 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1038/s41421-024-00766-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11880246/
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RNF10 and RIOK3 facilitate 40S ribosomal subunit degradation upon 60S biogenesis disruption or amino acid starvation

1
1. scibot 05 Mar 2025
  
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  CRL-3216
  
  DOI: 10.1016/j.celrep.2025.115371
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00142-1
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 05 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1111/febs.70033
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.70033
www.jneurosci.org www.jneurosci.org

Large Donor CRISPR for Whole-Coding Sequence Replacement of Cell Adhesion Molecule LRRTM2

1
1. scibot 04 Mar 2025
  
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  CRL-3216
  
  DOI: 10.1523/JNEUROSCI.1461-24.2024
  
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  Curator: @dhovakimyan1
  
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  DOI:10.1523/JNEUROSCI.1461-24.2024 RRID:CVCL_0063
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jneurosci.org/content/45/7/e1461242024
www.cell.com www.cell.com

Antigenic drift expands influenza viral escape pathways from recalled humoral immunity

1
1. scibot 04 Mar 2025
  
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  ATCCCat#CRL-3216
  
  DOI: 10.1016/j.immuni.2025.02.006
  
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cell.com/immunity/fulltext/S1074-7613(25)00074-3
onlinelibrary.wiley.com onlinelibrary.wiley.com

Serotonergic Psychedelics Rapidly Modulate Evoked Glutamate Release in Cultured Cortical Neurons

1
1. scibot 04 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1111/jnc.70020
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70020
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FEBS Press

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1. scibot 04 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1111/febs.70050
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.70050
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Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells

1
1. scibot 04 Mar 2025
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.immuni.2025.02.007
  
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Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape

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  RRID:CVCL_0063
  
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Preferential allosteric modulation of Otop1 channels by small molecule compounds

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Discovery and characterization of a novel telomerase alternative splicing isoform that protects lung cancer cells from chemotherapy induced cell death

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Anti-tumor efficacy and safety of AEV01 in preclinical glioblastoma and hepatocellular carcinoma models

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The critical role of enterovirus 2A protease in viral translation, replication, and antagonism of host antiviral responses

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  CRL-3216
  
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1-s2.0-S2589004225003785-main-html.html

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  ATCC, USA Cat#CRL-3216
  
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The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments

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ALS-linked VapB P56S mutation alters neuronal mitochondrial turnover at the synapse

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  ATCCCRL-3216
  
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PARP Inhibitors Differentially Regulate Immune Responses in Distinct Genetic Backgrounds of High-Grade Serous Tubo-Ovarian Carcinoma

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FEBS Press

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  RRID: CVCL_0063
  
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OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival

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OAS cross-activates RNase L intercellularly through cell-to-cell transfer of 2-5A to spread innate immunity

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  ATCCCat#CRL-3216
  
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Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors

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  ATCCCat#CRL-3216
  
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AKR1D1 suppresses liver cancer progression by promoting bile acid metabolism-mediated NK cell cytotoxicity

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  ATCCCRL-3216
  
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Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D

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Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98-rearranged leukemia

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1-s2.0-S2589004225003657-main-html.html

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Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism

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  RRID:CVCL_0063
  
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Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics

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  HEK293T
  
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Inhibition of GABARAP or GABARAPL1 prevents aminoglycoside- induced hearing loss

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TDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms

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  CRL-3216
  
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NAT10-mediated mRNA N4-acetylation is essential for the translational regulation during oocyte meiotic maturation in mice

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  DOI: 10.1126/sciadv.adp5163
  
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An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding

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SFP6 fluorescent probes for imaging SAM dynamics in living cells

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NAT10-mediated mRNA N4-acetylation is essential for the translational regulation during oocyte meiotic maturation in mice

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  RRID:CVCL_0063
  
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Mechano-oncogenic cytoskeletal remodeling drives leukemic transformation with mitochondrial vesicle-mediated STING activation

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Pharmacological characterisation of a clinical candidate, TG-0054, a small molecule inverse agonist targeting CXCR4

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EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models

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Single-cell sequencing elucidates the mechanism of NUSAP1 in glioma and its diagnostic and prognostic significance

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Clathrin functions in intracellular sorting during receptor-mediated endocytosis

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RSAD2: A pathogenic interferon-stimulated gene at the maternal-fetal interface of patients with systemic lupus erythematosus

1
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  ATCC CRL-3216
  
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CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer

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Methionine intervention induces PD-L1 expression to enhance the immune checkpoint therapy response in MTAP-deleted osteosarcoma

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  CVCL_0063
  
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Nucleic-acid-induced ZCCHC3 condensation promotes broad innate immune responses

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CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors

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Structural basis for channel gating and blockade in tri-heteromeric GluN1-2B-2D NMDA receptor

1
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  ATCCCRL-3216
  
  DOI: 10.1016/j.neuron.2025.01.013
  
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Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2

1
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Pre-clinical efficacy of CDK7 inhibitor-based combinations against myeloproliferative neoplasms (MPN) transformed to AML

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  RRID:CVCL_0063
  
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Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry

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  RRID:CVCL_0063
  
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BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor

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  RRID:CVCL_0063
  
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cir-24-0484-html.html

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The IAP antagonist tolinapant enhances the anti-tumor activity of cell therapies

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Targeting both the enzymatic and non-enzymatic functions of DHODH as a therapeutic vulnerability in c-Myc-driven cancer

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T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome

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Ligand-induced assembly of antibody variable fragments for the chemical regulation of biological processes

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  ATCCCat# CRL-3216
  
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PDF-html.html

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Interferon-a potentiates anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment

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Serotonin receptor HTR2B facilitates colorectal cancer metastasis via CREB1-ZEB1 axis mediated epithelial-mesenchymal transition

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Vasorin exocytosed from glioma cells facilitates angiogenesis via VEGFR2/AKT signaling pathway

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Synonymous mutations promote tumorigenesis by disrupting m6A-dependent mRNA metabolism

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The EMCV protein 2B* is required for efficient cell lysis via both caspase-3-dependent and -independent pathways during infection

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  HEK293T (human embryonic kidney, CRL-3216, ATCC)
  
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ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation

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MEK inhibitors lead to PDGFR pathway upregulation and sensitize tumors to RAF dimer inhibitors in NF1-deficient malignant peripheral nerve sheath tumor (MPNST)

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Mutant IDH modulates suppressive myeloid populations in malignant glioma

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Targeting GPC2 on intraocular and CNS metastatic retinoblastomas with local and systemic delivery of CAR T-cells

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can-24-0479-html.html

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Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer

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Arginine methylation of DDX3 by PRMT1 mediates mitochondrial homeostasis to promote breast cancer metastasis

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SPARC stabilizes ApoE to induce cholesterol-dependent invasion and sorafenib resistance in hepatocellular carcinoma

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A Genetically Encoded Magnetic Resonance Imaging Reporter Enables Sensitive Detection and Tracking of Spontaneous Metastases in Deep Tissues

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Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy

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1-s2.0-S2950329925000189-main-html.html

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RIOK3 mediates the degradation of 40S ribosomes

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Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids

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Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses

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Complex regulation of Cav2.2 N-type Ca2+ channels by Ca2+ and G-proteins

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DNAJB1-PRKACA Fusion Drives Fibrolamellar Liver Cancer through Impaired SIK Signaling and CRTC2/p300-Mediated Transcriptional Reprogramming

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Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer

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Development of a highly sensitive method to detect translational infidelity

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Single-molecule m6A detection empowered by endogenous labeling unveils complexities across RNA isoforms

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Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons

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Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon

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52.53.155.43 52.53.155.43

1-s2.0-S2589004225002226-main-html.html

1
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  ATCC Cat#CRL-3216
  
  DOI: 10.1016/j.isci.2025.111962
  
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Heterozygous pathogenic STT3A variation leads to dominant congenital glycosylation disorders and functional validation in zebrafish

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EMT-driven plasticity prospectively increases cell–cell variability to promote therapeutic adaptation in breast cancer

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Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12

1
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Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress in vivo

1
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Mechano-electrical transduction components TMC1-CIB2 undergo a Ca2+-induced conformational change linked to hearing loss

7
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
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Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development

2
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

7
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  RRID:CVCL_0063
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
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  RRID:CVCL_0063
  
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  RRID:CVCL_0063
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
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Dab1 expression level controls Reelin-induced PI3K-Akt activation in early GABAergic neurons

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Mitochondrial inhibitors reveal roles of specific respiratory chain complexes in CRY-dependent degradation of TIM

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In vivo engineering of murine T cells using the evolved adeno-associated virus variant Ark313

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Deubiquitinase USP9X controls Wnt signaling for CNS vascular formation and barrier maintenance

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Targeting gut S. aureofaciens Tü117 serves as a new potential therapeutic intervention for the prevention and treatment of hypertension

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Phosphorylation of SIRT7 by ATM causes DNA mismatch repair downregulation and adaptive mutability during chemotherapy

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  ATCCCRL-3216
  
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Rhodoquinone carries electrons in the mammalian electron transport chain

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  ATCCCRL-3216
  
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Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability

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Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import

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Novel Pannexin 1 isoform is increased in cancer

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Binding of HCN channels to GABAB receptors in dopamine neurons of the VTA limits synaptic inhibition and prevents the development of anxiety

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1-s2.0-S2589004225002147-main-html.html

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Oligodendrocytes drive neuroinflammation and neurodegeneration in Parkinson’s disease via the prosaposin-GPR37-IL-6 axis

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Structural basis of CXCR4 assembly and regulation

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Exercise-induced adipokine Nrg4 alleviates MASLD by disrupting hepatic cGAS-STING signaling

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Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3

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Harmine promotes axon regeneration through enhancing glucose metabolism

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A cellular model of TDP-43 induces phosphorylated TDP-43 aggregation with distinct changes in solubility and autophagy dysregulation

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High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects

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rAAV expressing a COBRA-designed influenza hemagglutinin generates a protective and durable adaptive immune response with a single dose

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Sialic acid aptamer and RNA in situ hybridization-mediated proximity ligation assay for spatial imaging of glycoRNAs in single cells

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The mitochondrial DNAJC co-chaperone TCAIM reduces α-ketoglutarate dehydrogenase protein levels to regulate metabolism

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Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture

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Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening

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Mechano-electrical transduction components TMC1-CIB2 undergo a Ca2+-induced conformational change linked to hearing loss

1
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis

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Cdk6’s functions are critically regulated by its unique C-terminus

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Nuclear mRNA Export Measurement Using FISH in iPSC-Derived Neurons

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Measuring Protein Nuclear Transport via a Dual Reporter in iPSC-Derived Neurons

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Preparation of Highly Pure hiPSC-Derived Motor Neurons Through Assembling a Co-culture System

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Lentiviral Delivery of Transcription Factors to Generate Motor Neurons from Human Induced Pluripotent Stem Cells

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PEBP1 amplifies mitochondrial dysfunction-induced integrated stress response

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Broadening a SARS-CoV-1–neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution

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GABAB Receptor Modulation of Membrane Excitability in Human Pluripotent Stem Cell-Derived Sensory Neurons by Baclofen and α-Conotoxin Vc1.1

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CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor

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Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase

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Article PDF-html.html

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xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023.1-miR-26a/30d/30e axis

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Structures and mRNP remodeling mechanism of the TREX-2 complex

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OXCT1 succinylation and activation by SUCLA2 promotes ketolysis and liver tumor growth

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Mina53 catalyzes arginine demethylation of p53 to promote tumor growth

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Bortezomib enhances the efficacy of BCMA CAR-T therapy through up-regulating BCMA expression in myeloma cells

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Endothelial lipase-binding peptides similar to netrin-1 inhibit hepatitis B virus infection

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CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition

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Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadth

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FEBS Press

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Single-cell analysis of neoplastic plasma cells identifies myeloma pathobiology mediators and potential targets

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Monocyte adhesion to and transmigration through endothelium following cardiopulmonary bypass shearing is mediated by IL-8 signaling

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ACE Loss Drives Renal Cell Carcinoma Growth and Invasion by Modulating AKT-FOXO1

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SLC1A4 Promotes Malignant Transformation of Hepatocellular Carcinoma by Activating the AKT Signaling

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BPS Publications

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Zfp106 binds to G-quadruplex RNAs and inhibits RAN translation and formation of RNA foci caused by G4C2 repeats

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Intestinal TM6SF2 protects against metabolic dysfunction-associated steatohepatitis through the gut–liver axis

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Designed mosaic nanoparticles enhance cross-reactive immune responses in mice

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A genome-wide association study identified PRKCB as a causal gene and therapeutic target for Mycobacterium avium complex disease

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Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation

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Recursive seed amplification detects distinct α-synuclein strains in cerebrospinal fluid of patients with Parkinson’s disease

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OSMOTIC STRESS INFLUENCES MICROTUBULE DRUG RESPONSE VIA WNK1 KINASE SIGNALING

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Passage of the HIV capsid cracks the nuclear pore

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