1,196 Matching Annotations
  1. Aug 2021
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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    sciencedirect.com/science/article/pii/S1931312818305584
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    Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome
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    sciencedirect.com/science/article/pii/S221112471931352X
  4. Jul 2021
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    An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma
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    sciencedirect.com/science/article/pii/S2211124719312987
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    Midkine promotes articular chondrocyte proliferation through the MK-LRP1-nucleolin signaling pathway
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    sciencedirect.com/science/article/pii/S0898656819302190
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    ncbi.nlm.nih.gov/pmc/articles/PMC6499541/
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    ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma
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    sciencedirect.com/science/article/pii/S221112472100872X
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    ncbi.nlm.nih.gov/pmc/articles/PMC6162341/
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.26115
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    OVA66 promotes tumour angiogenesis and progression through enhancing autocrine VEGF-VEGFR2 signalling
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    sciencedirect.com/science/article/pii/S2352396419301306
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    Critical individual roles of the BCR and FGFR1 kinase domains in BCR‐FGFR1‐driven stem cell leukemia/lymphoma syndrome
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32665
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    ANGPTL2 Promotes Inflammation via Integrin α5β1 in Chondrocytes - Mami Takano, Naoto Hirose, Chikako Sumi, Makoto Yanoshita, Sayuri Nishiyama, Azusa Onishi, Yuki Asakawa, Kotaro Tanimoto,
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    Regulator of G protein signaling 12 enhances osteoclastogenesis by suppressing Nrf2-dependent antioxidant proteins to promote the generation of reactive oxygen species
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    elifesciences.org/articles/42951
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    Quantitative description of the interactions among kinase cascades underlying long-term plasticity of Aplysia sensory neurons
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    nature.com/articles/s41598-021-94393-0
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    Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication
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    Long chain n-3 fatty acids attenuate oncogenic KRas-driven proliferation by altering plasma membrane nanoscale proteolipid composition
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    cancerres.aacrjournals.org/content/78/14/3899
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    Salmonella Typhi Colonization Provokes Extensive Transcriptional Changes Aimed at Evading Host Mucosal Immune Defense During Early Infection of Human Intestinal Tissue
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    TrkB‐mediated activation of the phosphatidylinositol‐3‐kinase/Akt cascade reduces the damage inflicted by oxygen‐glucose deprivation in area CA3 of the rat hippocampus
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    Selective androgen receptor modulator S42 suppresses prostate cancer cell proliferation
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    Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression
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    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
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    Sprouty1 regulates neuritogenesis and survival of cortical neurons
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    Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling
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    Sustained activation of ERK1/2 MAPK in Schwann cells causes corneal neurofibroma
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    Pierced Lasso Topology Controls Function in Leptin
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    Behavioral and cellular dopamine D1 and D3 receptor-mediated synergy: Implications for L-DOPA-induced dyskinesia
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    Maternal separation stress reduced prenatal-ethanol-induced increase in exploratory behaviour and extracellular signal-regulated kinase activity
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    Early ethanol exposure and vinpocetine treatment alter learning‐ and memory‐related proteins in the rat hippocampus and prefrontal cortex
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23894/full
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    Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis
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    Contextual Fear Memory Maintenance Changes Expression of pMAPK, BDNF and IBA-1 in the Pre-limbic Cortex in a Layer-Specific Manner
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    Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX
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    Npas4 regulates IQSEC3 expression in hippocampal somatostatin interneurons to mediate anxiety-like behavior
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    Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury
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    Microscopic image-based covariation network analysis for actin scaffold-modified insulin signaling
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    Gut-microbiota-targeted diets modulate human immune status
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    The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression
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    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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    Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits
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    Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target
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  51. Jun 2021
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    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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    sciencedirect.com/science/article/pii/S2211124721006628
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Planarian stem cells sense the identity of the missing pharynx to launch its targeted regeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC8219383/
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    Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
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    sciencedirect.com/science/article/pii/S2211124721006392
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    Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch
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    DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity
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    sciencedirect.com/science/article/pii/S2211124721006483
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    OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin
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    Protective effects of Da-cheng-qi decoction in rats with intracerebral hemorrhage
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    Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1
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    Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8187833/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC8203294/
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    Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma
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    Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening
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    NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma
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    Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality
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    The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia
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  67. May 2021
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression
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    ncbi.nlm.nih.gov/pmc/articles/PMC8143796/
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    Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome
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    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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    sciencedirect.com/science/article/pii/S1074761321001898
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    Cyclooxygenase inhibition attenuates brain angiogenesis and independently decreases mouse survival under hypoxia
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15291
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    Dynamic subcellular localization and transcription activity of the SRF cofactor MKL2 in the striatum are regulated by MAPK
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15303
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    VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway
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    UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8118655/
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    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
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    LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through MEK/ERK signaling pathway
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    PDZ domain protein SYNJ2BP regulates GRK-dependent Sst2A phosphorylation and downstream MAPK signaling
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    academic.oup.com/endo/article/162/2/bqaa229/6031468
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    Cell of Origin Influences Pancreatic Cancer Subtype
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    cancerdiscovery.aacrjournals.org/content/11/3/660
  79. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Synergistic interaction of nerve growth factor and glial cell‐line derived neurotrophic factor in muscular mechanical hyperalgesia in rats
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP280683
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    Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains
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    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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    The protective role of Ephrin-B2/EphB4 signaling in osteogenic differentiation under inflammatory environment
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    Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium
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    Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1-42 infused rat model
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    Diazepam and SL-327 synergistically attenuate anxiety-like behaviours in mice – Possible hippocampal MAPKs specificity
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    Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation
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    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
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    eEF2/eEF2K Pathway in the Mature Dentate Gyrus Determines Neurogenesis Level and Cognition
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    Rapid Effects of Selection on Brain-wide Activity and Behavior
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    Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC8079743/
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    Transient phases of OXPHOS inhibitor resistance reveal underlying metabolic heterogeneity in single cells
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  92. Apr 2021
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    Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
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    Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids
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