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  1. Jan 2020
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    The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis
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    A Simple DMSO-Based Method for Cryopreservation of Primary Hippocampal and Cortical Neurons
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    Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions: Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation
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    Insulin Potentiates JAK/STAT Signaling to Broadly Inhibit Flavivirus Replication in Insect Vectors
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    Systemic Root-Shoot Signaling Drives Jasmonate-Based Root Defense against Nematodes
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    Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6
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    Effects of the presence and absence of amino acids on translation, signaling and long‐term depression in hippocampal slices from Fmr1 knockout mice
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    GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis
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    N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration
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    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
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    A bidirectional network for appetite control in larval zebrafish
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    Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis
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    Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes
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    CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways
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    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury
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    Exploring Targeted Degradation Strategy for Oncogenic KRASG12C
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    IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer
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    YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression
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  21. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition
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      DOI: 10.1158/0008-5472.CAN-18-1888

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    The Neuropeptide Galanin Is Required for Homeostatic Rebound Sleep following Increased Neuronal Activity
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    ADAM17-dependent signaling is required for oncogenic human papillomavirus entry platform assembly
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    FGF signaling directs the cell fate switch from neurons to astrocytes in the developing mouse cerebral cortex
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    Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3
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    NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content
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    3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival
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    FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling
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    Glutathione transferase P silencing promotes neuronal differentiation of retinal R28 cells
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    O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
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    Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity
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    KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
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      DOI: 10.1016/j.ccell.2018.10.001

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    GM1 promotes TrkA‐mediated neuroblastoma cell differentiation by occupying a plasma membrane domain different from TrkA
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    SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis
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    sciencedirect.com/science/article/pii/S1535610818302307
  85. www.sciencedirect.com www.sciencedirect.com
    Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

      Curator: @anp055

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    sciencedirect.com/science/article/pii/S1535610818302289
  86. www.sciencedirect.com www.sciencedirect.com
    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
    1
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      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S0092867418300412
  87. www.sciencedirect.com www.sciencedirect.com
    Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
    1
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      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S1074761317304235
  88. www.sciencedirect.com www.sciencedirect.com
    Overcoming Resistance to Targeted Anticancer Therapies through Small-Molecule-Mediated MEK Degradation
    1
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      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S2451945618301557
  89. www.sciencedirect.com www.sciencedirect.com
    Encoding Growth Factor Identity in the Temporal Dynamics of FOXO3 under the Combinatorial Control of ERK and AKT Kinases
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S2405471218301923
  90. www.sciencedirect.com www.sciencedirect.com
    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
    1
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    sciencedirect.com/science/article/pii/S0092867418305865
  91. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance
    1
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    sciencedirect.com/science/article/pii/S1535610818301831
  92. academic.oup.com academic.oup.com
    The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

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    academic.oup.com/endo/article/159/6/2421/4990770
  93. www.sciencedirect.com www.sciencedirect.com
    Epithelial Sodium Channel Regulates Adult Neural Stem Cell Proliferation in a Flow-Dependent Manner
    1
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      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S1934590918301784
  94. academic.oup.com academic.oup.com
    EF24 (a curcumin analog) and ZSTK474 emphasizes the effect of cabozantinib in medullary thyroid cancer
    1
    1. scibot 05 Nov 2018
      RRID: AB_2315112

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    academic.oup.com/endo/article/159/6/2348/4980997
  95. www.sciencedirect.com www.sciencedirect.com
    B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S1074761318300293
  96. www.sciencedirect.com www.sciencedirect.com
    A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
    1
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    sciencedirect.com/science/article/pii/S1550413118301943
  97. www.sciencedirect.com www.sciencedirect.com
    A Hierarchical, Data-Driven Approach to Modeling Single-Cell Populations Predicts Latent Causes of Cell-To-Cell Variability
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S2405471218301480
  98. www.sciencedirect.com www.sciencedirect.com
    Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer
    1
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      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S1535610818300655
  99. www.sciencedirect.com www.sciencedirect.com
    Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610818301223
  100. www.sciencedirect.com www.sciencedirect.com
    Different Neuronal Activity Patterns Induce Different Gene Expression Programs
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

      Curator: @anp055

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    sciencedirect.com/science/article/pii/S089662731830285X
  101. www.sciencedirect.com www.sciencedirect.com
    Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518300017
  102. www.sciencedirect.com www.sciencedirect.com
    A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S0306452218302215
  103. www.sciencedirect.com www.sciencedirect.com
    Active Protection: Learning-Activated Raf/MAPK Activity Protects Labile Memory from Rac1-Independent Forgetting
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S0896627318301466
  104. www.sciencedirect.com www.sciencedirect.com
    Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S2405471218300541
  105. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S1535610817305020
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crk proteins transduce FGF signaling to promote lens fiber cell elongation
    1
    1. scibot 05 Nov 2018
      Rabbit anti-pERK1/2Cell SignalingCat. #: 4370

      Curator: @evieth

      Curator note: Cell Signaling Technology Cat# 4370 Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Rabbit mAb antibody

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    ncbi.nlm.nih.gov/pmc/articles/PMC5818251/
  107. www.karger.com www.karger.com
    Micro Integral Membrane Protein (MIMP), a Newly Discovered Anti-Inflammatory Protein of Lactobacillus Plantarum, Enhances the Gut Barrier and Modulates Microbiota and Inflammatory Cytokines
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

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    karger.com/Article/FullText/487027
  108. www.sciencedirect.com www.sciencedirect.com
    Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S1535610817305159
  109. www.sciencedirect.com www.sciencedirect.com
    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S153561081730555X
  110. www.sciencedirect.com www.sciencedirect.com
    Mechanical Forces Program the Orientation of Cell Division during Airway Tube Morphogenesis
    1
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      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S1534580717310298
  111. www.sciencedirect.com www.sciencedirect.com
    KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS
    1
    1. scibot 05 Nov 2018
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  112. www.sciencedirect.com www.sciencedirect.com
    Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression
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    sciencedirect.com/science/article/pii/S1934590917305106
  113. europepmc.org europepmc.org
    Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

      Curator: @evieth

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    europepmc.org/articles/PMC5663478/
  114. www.sciencedirect.com www.sciencedirect.com
    Systems Phytohormone Responses to Mitochondrial Proteotoxic Stress
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    sciencedirect.com/science/article/pii/S1097276517307554
  115. www.sciencedirect.com www.sciencedirect.com
    Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes
    1
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    sciencedirect.com/science/article/pii/S1934590917303211
  116. europepmc.org europepmc.org
    Methylglyoxal Requires AC1 and TRPA1 to Produce Pain and Spinal Neuron Activation.
    1
    1. scibot 05 Nov 2018
      RRID:AB_2315112

      Curator: @evieth

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    europepmc.org/articles/PMC5723675/
  117. www.sciencedirect.com www.sciencedirect.com
    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
    1
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    sciencedirect.com/science/article/pii/S1534580717308717
  118. academic.oup.com academic.oup.com
    IL-1β Inhibits Connexin 43 and Disrupts Decidualization of Human Endometrial Stromal Cells Through ERK1/2 and p38 MAP Kinase
    1
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      AB_2315112

      Curator: @evieth

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    academic.oup.com/endo/article/158/12/4270/4117214
  119. academic.oup.com academic.oup.com
    Region-Specific Suppression of Hypothalamic Responses to Insulin To Adapt to Elevated Maternal Insulin Secretion During Pregnancy
    1
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      AB_2315112

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    academic.oup.com/endo/article/158/12/4257/4283042
  120. europepmc.org europepmc.org
    Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.
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      RRID:AB_2315112

      Curator: @evieth

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    europepmc.org/articles/PMC5608509/
  121. Nov 2017
  122. onlinelibrary.wiley.com onlinelibrary.wiley.com
    EPA blocks TNF‐α‐induced inhibition of sugar uptake in Caco‐2 cells via GPR120 and AMPK
    1
    1. scibot 08 Nov 2017
      RRID:AB_2315112

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    onlinelibrary.wiley.com/doi/10.1002/jcp.26115/full
  123. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Role of the GM1 ganglioside oligosaccharide portion in the TrkA–dependent neurite sprouting in neuroblastoma cells
    1
    1. scibot 08 Nov 2017
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14146/full
  124. academic.oup.com academic.oup.com
    IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells
    1
    1. scibot 08 Nov 2017
      AB_2315112

      Curator: @patriciaelyse_

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    academic.oup.com/endo/article/158/10/3281/3885816/IL-1-Upregulates-StAR-and-Progesterone-Production
  125. www.sciencedirect.com www.sciencedirect.com
    Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria
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  126. www.sciencedirect.com www.sciencedirect.com
    Combinatorial Signal Perception in the BMP Pathway
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  127. f1000research.com f1000research.com
    Hepatic deletion of p110α and p85α results in insulin resistance despite sustained IRS1-associated phosphatidylinositol kinase activity
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    f1000research.com/articles/6-1600
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes
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  129. www.sciencedirect.com www.sciencedirect.com
    CycD/Cdk4 and Discontinuities in Dpp Signaling Activate TORC1 in the Drosophila Wing Disc
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  130. www.sciencedirect.com www.sciencedirect.com
    Dual ifgMosaic: A Versatile Method for Multispectral and Combinatorial Mosaic Gene-Function Analysis
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  131. www.sciencedirect.com www.sciencedirect.com
    Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C
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  132. www.sciencedirect.com www.sciencedirect.com
    Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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  134. www.jneurosci.org www.jneurosci.org
    ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase)
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  135. www.sciencedirect.com www.sciencedirect.com
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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  136. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A profile of auditory‐responsive neurons in the larval zebrafish brain
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    onlinelibrary.wiley.com/doi/10.1002/cne.24258/full
  137. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib
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  138. www.sciencedirect.com www.sciencedirect.com
    Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
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  139. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GLUL Promotes Cell Proliferation in Breast Cancer
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    onlinelibrary.wiley.com/doi/10.1002/jcb.25775/full
  140. www.sciencedirect.com www.sciencedirect.com
    Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation
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  141. www.sciencedirect.com www.sciencedirect.com
    An Adenosine Receptor for Olfaction in Fish
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    sciencedirect.com/science/article/pii/S0960982217304232
  142. www.sciencedirect.com www.sciencedirect.com
    RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma
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  143. academic.oup.com academic.oup.com
    Developmental Programming: Insulin Sensitizer Prevents the GnRH-Stimulated LH Hypersecretion in a Sheep Model of PCOS
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  144. www.sciencedirect.com www.sciencedirect.com
    Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation
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  145. www.sciencedirect.com www.sciencedirect.com
    A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos
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  146. www.sciencedirect.com www.sciencedirect.com
    Iterative Modeling Reveals Evidence of Sequential Transcriptional Control Mechanisms
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  147. www.sciencedirect.com www.sciencedirect.com
    Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biphasic Regulation of p38 MAPK by Serotonin Contributes to the Efficacy of Stimulus Protocols That Induce Long-Term Synaptic Facilitation
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    Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis
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  150. www.sciencedirect.com www.sciencedirect.com
    Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells
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  151. www.sciencedirect.com www.sciencedirect.com
    Feeding State Modulates Behavioral Choice and Processing of Prey Stimuli in the Zebrafish Tectum
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis
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  153. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Anatomical evidence that the uninjured adjacent L4 nerve plays a significant role in the development of peripheral neuropathic pain after L5 spinal nerve ligation in rats
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    onlinelibrary.wiley.com/doi/10.1002/cne.23750/full