1,833 Matching Annotations
  1. Jan 2022
  2. www.sciencedirect.com www.sciencedirect.com
    A fluorescence recovery after photobleaching protocol to measure surface diffusion of DAGLα in primary cultured cortical mouse neurons
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      DOI: 10.1016/j.xpro.2021.101118

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    sciencedirect.com/science/article/pii/S2666166721008248
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    Global RNA interactome of Salmonella discovers a 5′ UTR sponge for the MicF small RNA that connects membrane permeability to transport capacity
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    sciencedirect.com/science/article/pii/S1097276521011357
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    insomniac links the development and function of a sleep-regulatory circuit
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      DOI: 10.7554/eLife.65437

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    elifesciences.org/articles/65437
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    Metastasis enhancer PGRMC1 boosts store-operated Ca2+ entry by uncoiling Ca2+ sensor STIM1 for focal adhesion turnover and actomyosin formation
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    sciencedirect.com/science/article/pii/S2211124721017964
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    Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons
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      DOI: 10.7554/eLife.71185

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    ncbi.nlm.nih.gov/pmc/articles/PMC8754432/
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    Innate immune sensing of influenza A viral RNA through IFI16 promotes pyroptotic cell death
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    sciencedirect.com/science/article/pii/S2589004221016849
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    Endoplasmic reticulum-translocation is essential for APOL1 cellular toxicity
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    sciencedirect.com/science/article/pii/S2589004221016874
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    GS-CA1 and lenacapavir stabilize the HIV-1 core and modulate the core interaction with cellular factors
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    The sex determination gene doublesex regulates expression and secretion of the basement membrane protein Collagen IV
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    sciencedirect.com/science/article/pii/S1673852722000017
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    Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation
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    sciencedirect.com/science/article/pii/S2589004221016497
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    Identification and functional characterization of transcriptional activators in human cells
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    sciencedirect.com/science/article/pii/S1097276521010704
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    Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality
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    link.springer.com/article/10.1186/s12915-021-01220-z
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    Transmembrane topology and oligomeric nature of an astrocytic membrane protein, MLC1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8633789/
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    An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance
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    sciencedirect.com/science/article/pii/S2451945621005225
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    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
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    sciencedirect.com/science/article/pii/S1550413121006264
  17. Dec 2021
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    NAD kinase sustains lipogenesis and mitochondrial metabolismthrough fatty acid synthesis
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    Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase
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    RNA circles with minimized immunogenicity as potent PKR inhibitors
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    sciencedirect.com/science/article/pii/S1097276521010091
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    Toxoplasma gondii SAG1 Targeting Host Cell S100A6 for Parasite Invasion and Host Immunity
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    sciencedirect.com/science/article/pii/S2589004221014851
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    SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response
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      DOI: 10.1016/j.isci.2021.103562

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    sciencedirect.com/science/article/pii/S2589004221015327
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    Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
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    1. scibot 18 Dec 2021
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      DOI: 10.1016/j.neuron.2021.11.025

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    sciencedirect.com/science/article/pii/S0896627321009867
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    CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism
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      DOI: 10.1016/j.isci.2021.103538

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    sciencedirect.com/science/article/pii/S2589004221015091
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function
    1
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      DOI: 10.1016/j.isci.2021.103460

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  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation
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      DOI: 10.7554/eLife.70715

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    Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology
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      DOI: 10.7554/eLife.73430

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  28. www.cell.com www.cell.com
    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00996-5
  29. www.sciencedirect.com www.sciencedirect.com
    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
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      DOI: 10.1016/j.celrep.2021.110080

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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1
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      DOI: 10.7554/eLife.64688

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    ncbi.nlm.nih.gov/pmc/articles/PMC8641950/
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    NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
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    Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair
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    SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
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      DOI: 10.7554/eLife.67952

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    ncbi.nlm.nih.gov/pmc/articles/PMC8626089/
  35. www.embopress.org www.embopress.org
    Single-cell transcriptomics identifies Gadd45b as a regulator of herpesvirus-reactivating neurons
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      DOI: 10.15252/embr.202153543

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  36. Nov 2021
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    HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elucidation and refinement of synthetic receptor mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC7759213/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts
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    ncbi.nlm.nih.gov/pmc/articles/PMC8608148/
  40. www.nature.com www.nature.com
    MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA
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      DOI: 10.1038/s41467-021-27062-5

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    LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity
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    sciencedirect.com/science/article/pii/S2211124721015205
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    MAR1 links membrane adhesion to membrane merger during cell-cell fusion in Chlamydomonas
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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bi-allelic variants in OGDHL cause a neurodevelopmental spectrum disease featuring epilepsy, hearing loss, visual impairment, and ataxia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8715183/
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    Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
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    Structural mechanism for regulation of Rab7 by site-specific monoubiquitination
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    Cryo-Electron Microscopy Structures of VCP/p97 Reveal a New Mechanism of Oligomerization Regulation
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    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
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    DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks
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    ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress
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    The Lon protease temporally restricts polar cell differentiation events during the Caulobacter cell cycle
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    Transcriptional and chromatin-based partitioning mechanisms uncouple protein scaling from cell size
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    Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity
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    Reprogramming CBX8-PRC1 function with a positive allosteric modulator
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    P5A ATPase controls ER translocation of Wnt in neuronal migration
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    Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues
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    Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
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    TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis
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    Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy
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    Deiodinase-3 is a thyrostat to regulate podocyte homeostasis
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    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
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    Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome
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    An in vitro system to silence mitochondrial gene expression
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    The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly
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    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
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    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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    Genome-wide RNA structure changes during human neurogenesis modulate gene regulatory networks
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    Gene bookmarking by the heat shock transcription factor programs the insulin-like signaling pathway
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    SARS-CoV-2 integral membrane proteins shape the serological responses of patients with COVID-19
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    TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease
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    A phosphate starvation response-centered network regulates mycorrhizal symbiosis
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    Melatonin pretreatment alleviates the long-term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor-mediated Wnt signaling modulation
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    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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    Cancer cell immune mimicry delineates onco-immunologic modulation
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    The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression
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    Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice
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    RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis
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    Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1
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    Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
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    A prion accelerates proliferation at the expense of lifespan
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    Analysis of meiosis in Pristionchus pacificus reveals plasticity in homolog pairing and synapsis in the nematode lineage
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    Structural basis and regulation of the reductive stress response
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    ERα determines the chemoresistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressions
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    ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance
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    NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis
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