2,151 Matching Annotations
  1. Apr 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BPS Publications
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    ncbi.nlm.nih.gov/pmc/articles/PMC10119890/
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    UTP18-mediated p21 mRNA instability drives adenoma-carcinoma progression in colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124723004345
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    Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
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    sciencedirect.com/science/article/pii/S1550413123001304
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    Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue
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    sciencedirect.com/science/article/pii/S2589004223006296
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    Germline and somatic inactivating FLCN variants in parathyroid cancer and atypical parathyroid tumors
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgad136/7080719
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    The mechanism of STING autoinhibition and activation
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    sciencedirect.com/science/article/pii/S1097276523002435
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    Gαs slow conformational transition upon GTP binding and a novel Gαs regulator
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    sciencedirect.com/science/article/pii/S2589004223006806
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    Proteomic discovery of chemical probes that perturb protein complexes in human cells
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    sciencedirect.com/science/article/pii/S1097276523002393
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    Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut
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    sciencedirect.com/science/article/pii/S1931312823001117
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    Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication
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    sciencedirect.com/science/article/pii/S2211124723002978
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    A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans
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    journals.biologists.com/dev/article/150/6/dev201035/297263/A-proinsulin-dependent-interaction-between-ENPL-1
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    ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer
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    sciencedirect.com/science/article/pii/S1534580723001314
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    Ecdysone signaling determines lateral polarity and remodels neurites to form Drosophila’s left-right brain asymmetry
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    sciencedirect.com/science/article/pii/S2211124723003480
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    X-chromosome target specificity diverged between dosage compensation mechanisms of two closely related Caenorhabditis species
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    ncbi.nlm.nih.gov/pmc/articles/PMC10076027/
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    Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens
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    sciencedirect.com/science/article/pii/S1097276523002034
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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    sciencedirect.com/science/article/pii/S2211124723003522
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    SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology
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    sciencedirect.com/science/article/pii/S1097276523000837
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    Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis
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    sciencedirect.com/science/article/pii/S2211124723003388
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    The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia
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    sciencedirect.com/science/article/pii/S1534580723000990
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    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10066556/
  22. Mar 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10066556/
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    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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    sciencedirect.com/science/article/pii/S258900422300487X
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    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9949381/
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    Characterisation of the OTU domain deubiquitinase complement of Toxoplasma gondii
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    ncbi.nlm.nih.gov/pmc/articles/PMC10038098/
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    Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation
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    sciencedirect.com/science/article/pii/S1097276523001582
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    PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation
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    sciencedirect.com/science/article/pii/S2211124723002887
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    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
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    sciencedirect.com/science/article/pii/S2666166723001570
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    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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    sciencedirect.com/science/article/pii/S2211124723003200
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    Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence
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    sciencedirect.com/science/article/pii/S2211124723003224
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    The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus
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    sciencedirect.com/science/article/pii/S2211124723003170
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    A single-copy knockin translating ribosome immunoprecipitation toolkit for tissue-specific profiling of actively translated mRNAs in C. elegans
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    sciencedirect.com/science/article/pii/S2667237523000486
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    Structural basis for the Rad6 activation by the Bre1 N-terminal domain
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    ncbi.nlm.nih.gov/pmc/articles/PMC10036116/
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    Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10035768/
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    Nutrigenomic regulation of sensory plasticity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10036121/
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    Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10025096/
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    A central chaperone-like role for 14-3-3 proteins in human cells
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    Deficiency of WTAP in islet beta cells results in beta cell failure and diabetes in mice
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    link.springer.com/article/10.1007/s00125-023-05900-z
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    The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC10337519/
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    A combinatorial approach to uncover an additional Integrator subunit
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    sciencedirect.com/science/article/pii/S2211124723002553
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    Recruitment of Polo-like kinase couples synapsis to meiotic progression via inactivation of CHK-2
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    ncbi.nlm.nih.gov/pmc/articles/PMC9998088/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9481728/
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    LMAN1 is a receptor for house dust mite allergens
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    sciencedirect.com/science/article/pii/S221112472300219X
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    Cell context-dependent CFI-1/ARID3 functions control neuronal terminal differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC10124151/
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    FAM193A is a positive regulator of p53 activity
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    sciencedirect.com/science/article/pii/S2211124723002413
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin
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    ncbi.nlm.nih.gov/pmc/articles/PMC9986520/
  48. 52.53.155.43 52.53.155.43
    An AlphaFold2 map of the 53BP1 pathway identifies a direct SHLD3-RIF1 interaction critical for DNA repair activity
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    52.53.155.43/bf39226753014ebf0f6a94914d61bebfaafe36f8/2023.01.12.523815v1.full-html.html
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    Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
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    aacrjournals.org/cancerdiscovery/article/13/3/724/716757/Mutant-NPM1-Hijacks-Transcriptional-Hubs-to
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    JMJ28 guides sequence-specific targeting of ATX1/2-containing COMPASS-like complex in Arabidopsis
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    sciencedirect.com/science/article/pii/S2211124723001742
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    METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2
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    sciencedirect.com/science/article/pii/S2211124723001614
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    Linking chromatin acylation mark-defined proteome and genome in living cells
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    sciencedirect.com/science/article/pii/S0092867423001095
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16046
  54. www.science.org www.science.org
    Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
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    science.org/doi/10.1126/sciadv.ade2540
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    Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity
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    sciencedirect.com/science/article/pii/S2211124723002164
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    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
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    sciencedirect.com/science/article/pii/S2211124723001997
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    Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
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    ncbi.nlm.nih.gov/pmc/articles/PMC9946360/
  58. www.pnas.org www.pnas.org
    Epigenetic function during heroin self-administration controls future relapse-associated behavior in a cell type-specific manner
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    pnas.org/doi/abs/10.1073/pnas.2210953120
  59. Feb 2023
  60. www.sciencedirect.com www.sciencedirect.com
    PIMT regulates Hepatic Gluconeogenesis in Mice
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    sciencedirect.com/science/article/pii/S2589004223001979
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    Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction
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    sciencedirect.com/science/article/pii/S2451945623000338
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    Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames
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    sciencedirect.com/science/article/pii/S1097276523000758
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    Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein
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    sciencedirect.com/science/article/pii/S1931312823000392
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRF3 activates mTORC1 arginine-dependently for cancer cell viability
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    ncbi.nlm.nih.gov/pmc/articles/PMC9932127/
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    Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
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    sciencedirect.com/science/article/pii/S1074761323000390
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    Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
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    ncbi.nlm.nih.gov/pmc/articles/PMC9931222/
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    STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice
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    academic.oup.com/endo/article/164/3/bqac215/6967061
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    Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma
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    Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control
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    sciencedirect.com/science/article/pii/S1097276523000722
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    Human hematopoietic stem cell vulnerability to ferroptosis
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    sciencedirect.com/science/article/pii/S0092867423000508
  72. elifesciences.org elifesciences.org
    A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection
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    elifesciences.org/articles/83534
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    Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models
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    sciencedirect.com/science/article/pii/S1043661823000488
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    Pluripotency retention and exogenous mRNA introduction in planarian stem cells in culture
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    Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules
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    sciencedirect.com/science/article/pii/S0092867422016294
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    An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation
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    sciencedirect.com/science/article/pii/S2451945623000260
  77. Jan 2023
  78. www.sciencedirect.com www.sciencedirect.com
    The lipid transporter ORP2 regulates synaptic neurotransmitter release via two distinct mechanisms
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    sciencedirect.com/science/article/pii/S2211124722017788
  79. www.cell.com www.cell.com
    Fungal CFEM effectors negatively regulate a maize wall-associated kinase by interacting with its alternatively spliced variant to dampen resistance
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    cell.com/cell-reports/fulltext/S2211-1247(22)01773-9
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    Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress
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    BRPF1 bridges H3K4me3 and H3K23ac in human ESCs and is essential to pluripotency
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    ncbi.nlm.nih.gov/pmc/articles/PMC9874078/
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    Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation
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    sciencedirect.com/science/article/pii/S1097276522012163
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    SUMOylation of HNRNPA2B1 modulates RPA dynamics during unperturbed replication and genotoxic stress responses
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    SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum
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    ncbi.nlm.nih.gov/pmc/articles/PMC10010011/
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    Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA
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    sciencedirect.com/science/article/pii/S0896627322011540
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    Protocol to measure centrosome cohesion deficits mediated by pathogenic LRRK2 in cultured cells using confocal microscopy
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    sciencedirect.com/science/article/pii/S2666166722009042
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    The NLRP1 and CARD8 inflammasomes detect reductive stress
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    sciencedirect.com/science/article/pii/S2211124722018708
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    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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    ncbi.nlm.nih.gov/pmc/articles/PMC9839780/
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    Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC9831603/
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    Human SMARCA5 is continuously required to maintain nucleosome spacing
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    sciencedirect.com/science/article/pii/S1097276522011753
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9306355/
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    Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
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