2,090 Matching Annotations
  1. Feb 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRF3 activates mTORC1 arginine-dependently for cancer cell viability
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    ncbi.nlm.nih.gov/pmc/articles/PMC9932127/
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    Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
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    sciencedirect.com/science/article/pii/S1074761323000390
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    Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
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    ncbi.nlm.nih.gov/pmc/articles/PMC9931222/
  5. academic.oup.com academic.oup.com
    STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice
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    academic.oup.com/endo/article/164/3/bqac215/6967061
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    cd-22-0376-html.html
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    Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma
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    sciencedirect.com/science/article/pii/S2211124723001146
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    Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control
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    sciencedirect.com/science/article/pii/S1097276523000722
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    Human hematopoietic stem cell vulnerability to ferroptosis
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    sciencedirect.com/science/article/pii/S0092867423000508
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    A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection
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    elifesciences.org/articles/83534
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    Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models
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    sciencedirect.com/science/article/pii/S1043661823000488
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    Pluripotency retention and exogenous mRNA introduction in planarian stem cells in culture
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    sciencedirect.com/science/article/pii/S2589004223000780
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    Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules
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    sciencedirect.com/science/article/pii/S0092867422016294
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    An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation
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    sciencedirect.com/science/article/pii/S2451945623000260
  15. Jan 2023
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    The lipid transporter ORP2 regulates synaptic neurotransmitter release via two distinct mechanisms
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    sciencedirect.com/science/article/pii/S2211124722017788
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    Fungal CFEM effectors negatively regulate a maize wall-associated kinase by interacting with its alternatively spliced variant to dampen resistance
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    cell.com/cell-reports/fulltext/S2211-1247(22)01773-9
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    Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress
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    sciencedirect.com/science/article/pii/S2211124723000529
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRPF1 bridges H3K4me3 and H3K23ac in human ESCs and is essential to pluripotency
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    ncbi.nlm.nih.gov/pmc/articles/PMC9874078/
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    Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation
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    sciencedirect.com/science/article/pii/S1097276522012163
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    SUMOylation of HNRNPA2B1 modulates RPA dynamics during unperturbed replication and genotoxic stress responses
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    sciencedirect.com/science/article/pii/S1097276523000035
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    SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum
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    ncbi.nlm.nih.gov/pmc/articles/PMC10010011/
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    Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA
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    sciencedirect.com/science/article/pii/S0896627322011540
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    Protocol to measure centrosome cohesion deficits mediated by pathogenic LRRK2 in cultured cells using confocal microscopy
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    sciencedirect.com/science/article/pii/S2666166722009042
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    The NLRP1 and CARD8 inflammasomes detect reductive stress
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    sciencedirect.com/science/article/pii/S2211124722018708
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    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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    ncbi.nlm.nih.gov/pmc/articles/PMC9839780/
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    Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC9831603/
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    Human SMARCA5 is continuously required to maintain nucleosome spacing
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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9306355/
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    Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9574375/
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    Evolutionarily conserved regulators of tau identify targets for new therapies
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    sciencedirect.com/science/article/pii/S0896627322010856
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    The human pre-replication complex is an open complex
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    A central role for regulated protein stability in the control of TFE3 and MITF by nutrients
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    Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy
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    sciencedirect.com/science/article/pii/S1097276522011376
  35. academic.oup.com academic.oup.com
    Two modes of Cue2-mediated mRNA cleavage with distinct substrate recognition initiate no-go decay
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1172/6965460
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    The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation
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    sciencedirect.com/science/article/pii/S2211124722018058
  37. Dec 2022
  38. 52.53.155.43 52.53.155.43
    POU1F1/Pou1f1 c.143-83A > G variant disrupts the branch site in pre-mRNA and leads dwarfism
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    The ADP-ribose hydrolase NUDT5 is important for DNA repair
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    sciencedirect.com/science/article/pii/S2211124722017624
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    The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model
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    sciencedirect.com/science/article/pii/S2211124722017296
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    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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    sciencedirect.com/science/article/pii/S1534580722008152
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    Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines
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    Epidermal stratification requires retromer-mediated desmoglein-1 recycling
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    sciencedirect.com/science/article/pii/S1534580722008103
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    Elongation factor-specific capture of RNA polymerase II complexes
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    sciencedirect.com/science/article/pii/S2667237522002703
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    PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing
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    sciencedirect.com/science/article/pii/S1097276522010991
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    Mitochondrial cristae architecture protects against mtDNA release and inflammation
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    sciencedirect.com/science/article/pii/S2211124722016576
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15726
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    IFT-A structure reveals carriages for membrane protein transport into cilia
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    sciencedirect.com/science/article/pii/S0092867422014222
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9713376/
  51. www.nature.com www.nature.com
    Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice
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    nature.com/articles/s41401-022-01024-z
  52. Nov 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcm2 promotes stem cell differentiation via its ability to bind H3-H4
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    ncbi.nlm.nih.gov/pmc/articles/PMC9681210/
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    The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2
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    sciencedirect.com/science/article/pii/S2211124722014978
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    Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression
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    sciencedirect.com/science/article/pii/S2211124722015650
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq
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    ncbi.nlm.nih.gov/pmc/articles/PMC9676202/
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13322
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9672935/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC9450962/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9646953/
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    Purification of exosome-enriched proteins produced in a Drosophila cell line by size exclusion chromatography
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    sciencedirect.com/science/article/pii/S2666166722007146
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    CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors
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    sciencedirect.com/science/article/pii/S0896627322009473
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    LncRNA CCTT-mediated RNA-DNA and RNA-protein interactions facilitate the recruitment of CENP-C to centromeric DNA during kinetochore assembly
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell intrinsic TIM-3 induces glioblastoma progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9618784/
  65. rupress.org rupress.org
    V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
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    rupress.org/jcb/article/222/1/e202205045/213623/V-ATPase-TORC1-mediated-ATFS-1-translation-directs
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    Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
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    sciencedirect.com/science/article/pii/S2451945622003592
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    An enChIP system for the analysis of genome functions in budding yeast
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    academic.oup.com/biomethods/article/7/1/bpac025/6762078
  68. Oct 2022
  69. www.sciencedirect.com www.sciencedirect.com
    Structure and functionality of a multimeric human COQ7:COQ9 complex
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    sciencedirect.com/science/article/pii/S1097276522009601
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9589213/
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    METTL3 regulates m6A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma
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    sciencedirect.com/science/article/pii/S2211124722013869
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    A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation
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    sciencedirect.com/science/article/pii/S2211124722013985
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZBTB7A promotes virus-host homeostasis during human coronavirus 229E infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC9533670/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolomic fingerprinting of renal disease progression in Bardet-Biedl syndrome reveals mitochondrial dysfunction in kidney tubular cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9587000/
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    ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins
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    sciencedirect.com/science/article/pii/S109727652200956X
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    Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer
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    Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas
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    RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA
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    sciencedirect.com/science/article/pii/S1097276522009352
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    Allelic variation in the Arabidopsis TNL CHS3/CSA1 immune receptor pair reveals two functional cell-death regulatory modes
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    sciencedirect.com/science/article/pii/S1931312822004693
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    CasPlay provides a gRNA-barcoded CRISPR-based display platform for antibody repertoire profiling
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    sciencedirect.com/science/article/pii/S2667237522002089
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    Brain-wide connectivity map of mouse thermosensory cortices
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    academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhac386/6762895
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    A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation
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    elifesciences.org/articles/79771
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    GPC3-Unc5 receptor complex structure and role in cell migration
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    sciencedirect.com/science/article/pii/S0092867422011977
  84. www.cell.com www.cell.com
    Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity
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    cell.com/neuron/fulltext/S0896-6273(22)00860-1
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    Spatial epitope barcoding reveals clonal tumor patch behaviors
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    sciencedirect.com/science/article/pii/S1535610822004433
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    The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling
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    sciencedirect.com/science/article/pii/S2589004222013384
  87. www.nature.com www.nature.com
    Enzyme-free targeted DNA demethylation using CRISPR–dCas9-based steric hindrance to identify DNA methylation marks causal to altered gene expression
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    nature.com/articles/s41596-022-00741-3
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dissection of the MEF2D-IRF8 transcriptional circuit dependency in acute myeloid leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9526175/
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    Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex
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    sciencedirect.com/science/article/pii/S1097276522008954
  90. Sep 2022
  91. www.embopress.org www.embopress.org
    Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
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    embopress.org/doi/10.15252/embr.202154136
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    Continuous double-strand break induction and their differential processing sustain chiasma formation during Caenorhabditis elegans meiosis
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    sciencedirect.com/science/article/pii/S2211124722012402
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct regions of H. pylori’s bactofilin CcmA regulate protein–protein interactions to control helical cell shape
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    ncbi.nlm.nih.gov/pmc/articles/PMC9507126/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The core PCP protein Prickle2 regulates axon number and AIS maturation by binding to AnkG and modulating microtubule bundling
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