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1,289 Matching Annotations

Jul 2021
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Acrylamide Retards the Slow Axonal Transport of Neurofilaments in Rat Cultured Dorsal Root Ganglia Neurons and the Corresponding Mechanisms - Springer

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1. scibot 27 Jul 2021
  
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  DOI: 10.1007/s11064-015-1782-z
  
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link.springer.com/article/10.1007/s11064-015-1782-z/fulltext.html
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Acute administration of ucf-101 ameliorates the locomotor impairments induced by a traumatic spinal cord injury

1
1. scibot 27 Jul 2021
  
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  DOI: 10.1016/j.neuroscience.2015.05.036
  
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sciencedirect.com/science/article/pii/S0306452215004789
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Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

1
1. scibot 22 Jul 2021
  
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  DOI: 10.1016/j.ccell.2021.06.016
  
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sciencedirect.com/science/article/pii/S153561082100338X
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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

1
1. scibot 22 Jul 2021
  
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  DOI: 10.1016/j.cell.2021.06.028
  
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sciencedirect.com/science/article/pii/S0092867421007960
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Neuroplasticity and inflammatory alterations in the nucleus accumbens are corrected after risperidone treatment in a schizophrenia-related developmental model in rats

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1. scibot 22 Jul 2021
  
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  DOI: 10.1016/j.schres.2021.07.014
  
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sciencedirect.com/science/article/pii/S092099642100267X
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Protocol for cell preparation and gene delivery in HEK293T and C2C12 cells

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1. scibot 20 Jul 2021
  
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  DOI: 10.1016/j.xpro.2021.100497
  
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sciencedirect.com/science/article/pii/S2666166721002045
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Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis

1
1. scibot 14 Jul 2021
  
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  DOI: 10.1016/j.celrep.2021.109361
  
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sciencedirect.com/science/article/pii/S2211124721007592
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Dysregulation of GABAA Receptor-Mediated Neurotransmission during the Auditory Cortex Critical Period in the Fragile X Syndrome Mouse Model

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1. scibot 09 Jul 2021
  
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  DOI: 10.1093/cercor/bhab203
  
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academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhab203/6314720
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SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice

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1. scibot 07 Jul 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.molcel.2021.06.003
  
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sciencedirect.com/science/article/pii/S1097276521004500
www.cell.com www.cell.com

Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency

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1. scibot 03 Jul 2021
  
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  DOI: 10.1016/j.molcel.2021.06.011
  
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cell.com/molecular-cell/fulltext/S1097-2765(21)00458-5
Jun 2021
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Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy

1
1. scibot 30 Jun 2021
  
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  DOI: 10.1016/j.devcel.2021.06.003
  
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sciencedirect.com/science/article/pii/S1534580721004810
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Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition

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1. scibot 30 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2021.109291
  
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sciencedirect.com/science/article/pii/S2211124721006628
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CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice

1
1. scibot 29 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1210/endocr/bqab064
  
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academic.oup.com/endo/article/162/6/bqab064/6188411
journals.sagepub.com journals.sagepub.com

Neuronal Pentraxin 1 Promotes Hypoxic-Ischemic Neuronal Injury by Impairing Mitochondrial Biogenesis via Interactions With Active Bax[6A7] and Mitochondrial Hexokinase II - Md Al Rahim, Shabarish Thatipamula, Giulio M. Pasinetti, Mir Ahamed Hossain, 2021

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1. scibot 26 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1177/17590914211012888
  
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2. scibot 12 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1177/17590914211012888
  
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journals.sagepub.com/doi/10.1177/17590914211012888
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Targeting ribosomal G-quadruplexes with naphthalene-diimides as RNA polymerase I inhibitors for colorectal cancer treatment

1
1. scibot 24 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.chembiol.2021.05.021
  
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sciencedirect.com/science/article/pii/S245194562100266X
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Nitric Oxide and heme-NO stimulate superoxide production by NADPH Oxidase 5

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1. scibot 19 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.freeradbiomed.2021.06.008
  
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sciencedirect.com/science/article/pii/S0891584921003737
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability

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1. scibot 18 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.isci.2021.102534
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8184511/
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A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

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1. scibot 16 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.3390/cancers13112840
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

1
1. scibot 12 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.cmet.2021.05.016
  
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sciencedirect.com/science/article/pii/S1550413121002333
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Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library

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1. scibot 10 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.chembiol.2021.05.009
  
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sciencedirect.com/science/article/pii/S2451945621002543
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TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease

1
1. scibot 09 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.cmet.2021.05.014
  
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sciencedirect.com/science/article/pii/S155041312100231X
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Specific activation of GluN1-N2B NMDA receptors underlies facilitation of cortical spreading depression in a genetic mouse model of migraine with reduced astrocytic glutamate clearance

1
1. scibot 08 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.nbd.2021.105419
  
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sciencedirect.com/science/article/pii/S0969996121001686
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Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1

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1. scibot 08 Jun 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.scr.2021.102415
  
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sciencedirect.com/science/article/pii/S1873506121002610
May 2021
www.nature.com www.nature.com

Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure

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1. scibot 29 May 2021
  
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  RRID:AB_476744
  
  DOI: 10.1038/s41398-021-01421-8
  
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nature.com/articles/s41398-021-01421-8
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Adhesion-mediated mechanosignaling forces mitohormesis

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1. scibot 21 May 2021
  
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  DOI: 10.1016/j.cmet.2021.04.017
  
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sciencedirect.com/science/article/pii/S1550413121001832
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Implementation of dietary methionine restriction using casein after selective, oxidative deletion of methionine

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1. scibot 14 May 2021
  
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  DOI: 10.1016/j.isci.2021.102470
  
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sciencedirect.com/science/article/pii/S2589004221004387
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Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway

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1. scibot 14 May 2021
  
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  DOI: 10.1016/j.isci.2021.102504
  
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sciencedirect.com/science/article/pii/S2589004221004727
www.tandfonline.com www.tandfonline.com

CREG1 promotes lysosomal biogenesis and function

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1. scibot 14 May 2021
  
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  DOI: 10.1080/15548627.2021.1909997
  
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tandfonline.com/doi/abs/10.1080/15548627.2021.1909997
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Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells

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1. scibot 12 May 2021
  
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  DOI: 10.1016/j.immuni.2021.04.012
  
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sciencedirect.com/science/article/pii/S1074761321001746
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RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis

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1. scibot 12 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109112
  
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sciencedirect.com/science/article/pii/S2211124721004460
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Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities

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1. scibot 11 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109126
  
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sciencedirect.com/science/article/pii/S2211124721004654
academic.oup.com academic.oup.com

IGSF1 does not regulate spermatogenesis or modify FSH synthesis in response to inhibins or activins

1
1. scibot 10 May 2021
  
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  RRID:AB_476744
  
  DOI: 10.1210/jendso/bvab023
  
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academic.oup.com/jes/article/5/4/bvab023/6145153
onlinelibrary.wiley.com onlinelibrary.wiley.com

Binge‐Like Ethanol Drinking Activates ALK Signaling and Increases the Expression of STAT3 Target Genes in the Mouse Hippocampus and Prefrontal Cortex

1
1. scibot 10 May 2021
  
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  DOI: 10.1111/gbb.12729
  
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onlinelibrary.wiley.com/doi/10.1111/gbb.12729
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Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue

1
1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2021.01.002
  
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sciencedirect.com/science/article/pii/S1934590921000023
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A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy

1
1. scibot 08 May 2021
  
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A comprehensive phenotypic CRISPR-Cas9 screen of the ubiquitin pathway uncovers roles of ubiquitin ligases in mitosis

1
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  DOI: 10.1016/j.molcel.2021.01.014
  
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TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology

1
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Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity

1
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Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation

1
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Fetal and postnatal zinc restriction: sex differences in the renal renin-angiotensin system of newborn and adult Wistar rats

1
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Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis

1
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Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment

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PIWI proteomics identifies Atari and Pasilla as piRNA biogenesis factors in Aedes mosquitoes

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Glutamine Metabolism Controls Chondrocyte Identity and Function

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The Targeting of MRE11 or RAD51 Sensitizes Colorectal Cancer Stem Cells to CHK1 Inhibition

1
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  DOI: 10.3390/cancers13081957
  
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An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity

1
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Hypomorph Mutation-Directed Small-Molecule Protein-Protein Interaction Inducers to Restore Mutant SMAD4-Suppressed TGF-β Signaling

2
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Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas

1
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IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

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Endoplasmic reticulum oxidoreductase 1 alpha modulates prostate cancer hallmarks

1
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  DOI: 10.21037/tau-20-1025
  
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Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport

1
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  DOI: 10.1016/j.celrep.2021.108971
  
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Nanog is a promising chemo‐resistant stemness marker and therapeutic target by iron chelators for esophageal cancer

1
1. scibot 09 Apr 2021
  
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  anti‐β‐actin
  
  DOI: 10.1002/ijc.33544
  
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Co‐culture of exogenous oligodendrocytes with unmyelinated cerebella: Revisiting ex vivo models and new tools to study myelination

1
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  DOI: 10.1002/glia.24001
  
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academic.oup.com academic.oup.com

microRNA-483 protects pancreatic beta-cells by targeting ALDH1A3

1
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  DOI: 10.1210/endocr/bqab031
  
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High KIFC1 expression is associated with poor prognosis in prostate cancer

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  DOI: 10.1007/s12032-021-01494-x
  
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The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism

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COX2 regulates senescence secretome composition and senescence surveillance through PGE2

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  DOI: 10.1016/j.celrep.2021.108860
  
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Targeting alveolar‐specific succinate dehydrogenase A attenuates pulmonary inflammation during acute lung injury

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  DOI: 10.1096/fj.202002778R
  
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HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration

1
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  DOI: 10.7554/eLife.61531
  
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PTEN dephosphorylates Abi1 to promote epithelial morphogenesis

1
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  DOI: 10.1083/jcb.201910041
  
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The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses

1
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  DOI: 10.1016/j.immuni.2020.11.003
  
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GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo

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  DOI: 10.1186/s12915-021-00966-w
  
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Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

1
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  DOI: 10.1016/j.ebiom.2021.103255
  
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Ubiquitination and the Proteasome rather than Caspase‐3‐Mediated C‐Terminal Cleavage are Involved in the EAAT2 Degradation by Staurosporine‐Induced Cellular Stress

1
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  DOI: 10.1111/jnc.15237
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15237
Feb 2021
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microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP

1
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  DOI: 10.1016/j.molcel.2021.01.030
  
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Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice

1
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  DOI: 10.1038/s41467-020-20112-4
  
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The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1

1
1. scibot 27 Feb 2021
  
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  A5441
  
  DOI: 10.1074/jbc.RA120.015162
  
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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

1
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  DOI: 10.1016/j.cell.2020.11.042
  
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Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts

1
1. scibot 27 Feb 2021
  
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  DOI: 10.3389/fimmu.2020.579266
  
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Bicuculline regulated protein synthesis is dependent on homer1 and promotes its interaction with eEF2K through mTORC1 dependent phosphorylation

1
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  RRID:AB_476744
  
  DOI: 10.1111/jnc.15178
  
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Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer

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  DOI: 10.7554/eLife.58810
  
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Heme Oxygenase 1 in Schwann Cells Regulates Peripheral Nerve Degeneration Against Oxidative Stress

1
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  DOI: 10.1177/1759091419838949
  
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Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts

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  DOI: 10.7554/eLife.40744
  
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PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis

1
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  AB_476744
  
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academic.oup.com/endo/article/162/4/bqab015/6121258
journals.sagepub.com journals.sagepub.com

ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation - Limin Wu, Mohammad R Islam, Janice Lee, Hajime Takase, Shuzhen Guo, Allison M Andrews, Tetyana P Buzhdygan, Justin Mathew, Wenlu Li, Ken Arai, Eng H Lo, Servio H Ramirez, Josephine Lok, 2021

1
1. scibot 25 Feb 2021
  
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  β-actin
  
  DOI: 10.1177/0271678X20984976
  
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Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation

1
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  DOI: 10.1371/journal.pone.0232637
  
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A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain

1
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  DOI: 10.7554/eLife.54873
  
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biosignaling.biomedcentral.com biosignaling.biomedcentral.com

L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness

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  DOI: 10.1186/s12964-021-00710-5
  
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biosignaling.biomedcentral.com/articles/10.1186/s12964-021-00710-5
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Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53

1
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  DOI: 10.1016/j.molcel.2020.12.008
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30900-X
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Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation

1
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  DOI: 10.1016/j.molcel.2020.11.036
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30836-4
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In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition

1
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  DOI: 10.1016/j.molcel.2020.11.027
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30827-3
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Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling

1
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  DOI: 10.1016/j.celrep.2021.108765
  
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sciencedirect.com/science/article/pii/S2211124721000784
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Exercise Modulates Chloride Homeostasis after Spinal Cord Injury

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  DOI: 10.1523/JNEUROSCI.0678-14.2014
  
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jneurosci.org/content/34/27/8976.long
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Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab

1
1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.celrep.2020.01.012
  
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cell.com/cell-reports/abstract/S2211-1247(20)30021-8
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5’ValCAC tRNA fragment generated as part of a protective angiogenin response provides prognostic value in amyotrophic lateral sclerosis

1
1. scibot 09 Feb 2021
  
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  DOI: 10.1093/braincomms/fcaa138
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7850272/
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Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs

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  DOI: 10.1016/j.celrep.2021.108715
  
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sciencedirect.com/science/article/pii/S2211124721000280
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AD7c-NTP Impairs Adult Striatal Neurogenesis by Affecting the Biological Function of MeCP2 in APP/PSl Transgenic Mouse Model of Alzheimer's Disease

1
1. scibot 31 Jan 2021
  
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  RRID:AB_476744
  
  DOI: 10.3389/fnagi.2020.616614
  
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frontiersin.org/article/10.3389/fnagi.2020.616614/full
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The half-life of the bone-derived hormone osteocalcin is regulated through O-glycosylation in mice, but not in humans

1
1. scibot 29 Jan 2021
  
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  DOI: 10.7554/eLife.61174
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7822592/
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Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair‐deficient mice

1
1. scibot 26 Jan 2021
  
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  RRID:AB_476744
  
  DOI: 10.1111/acel.13302
  
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onlinelibrary.wiley.com/doi/full/10.1111/acel.13302
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Mechanical Loading-Driven Tumor Suppression Is Mediated by Lrp5-Dependent and Independent Mechanisms

1
1. scibot 26 Jan 2021
  
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  RRID:AB_476744
  
  DOI: 10.3390/cancers13020267
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7828232/
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The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway

1
1. scibot 20 Jan 2021
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.108659
  
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sciencedirect.com/science/article/pii/S221112472031648X
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Voltage-independent GluN2A-type NMDA receptor Ca 2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice

1
1. scibot 12 Jan 2021
  
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  RRID:AB_476744
  
  DOI: 10.1038/s42003-020-01538-4
  
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nature.com/articles/s42003-020-01538-4
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OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy

1
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.108579
  
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Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity

1
1. scibot 07 Jan 2021
  
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  DOI: 10.1016/j.celrep.2020.108601
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7839063/
Dec 2020
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Translation in amino-acid-poor environments is limited by tRNAGln charging

1
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  RRID:AB_476744
  
  DOI: 10.7554/eLife.62307
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7744096/
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Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth

1
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  DOI: 10.1016/j.celrep.2020.108544
  
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sciencedirect.com/science/article/pii/S2211124720315333
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Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs

1
1. scibot 13 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108475
  
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sciencedirect.com/science/article/pii/S2211124720314649
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Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5

1
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  DOI: 10.1016/j.celrep.2020.108490
  
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Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction

1
1. scibot 10 Dec 2020
  
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  DOI: 10.3389/fphys.2020.593966
  
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frontiersin.org/article/10.3389/fphys.2020.593966/full
www.embopress.org www.embopress.org

Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA

1
1. scibot 07 Dec 2020
  
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  anti‐Actin
  
  DOI: 10.15252/embj.2019103654
  
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embopress.org/doi/abs/10.15252/embj.2019103654
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TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson’s Disease

1
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  DOI: 10.1016/j.celrep.2020.108418
  
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BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor

1
1. scibot 07 Dec 2020
  
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  DOI: 10.7554/eLife.58069
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7688313/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

A novel HDAC6 inhibitor improves myelination of Schwann cells in a model of Charcot‐Marie‐Tooth disease type 1A

1
1. scibot 07 Dec 2020
  
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  RRID:AB_476744
  
  DOI: 10.1111/bph.15231
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15231
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Activity-Based Anorexia Dynamically Dysregulates the Glutamatergic Synapse in the Nucleus Accumbens of Female Adolescent Rats

1
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  RRID:AB_476744
  
  DOI: 10.3390/nu12123661
  
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mdpi.com/2072-6643/12/12/3661
Nov 2020
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Prefrontal cortex miR‐874‐3p prevents lipopolysaccharide‐induced depression‐like behavior through inhibition of indoleamine 2,3‐dioxygenase 1 expression in mice.

1
1. scibot 19 Nov 2020
  
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  RRID:AB_476744
  
  DOI: 10.1111/jnc.15222
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15222
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Lysophosphatidic acid induces thrombospondin‐1 production in primary cultured rat cortical astrocytes

1
1. scibot 19 Nov 2020
  
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  RRID:AB_476744
  
  DOI: 10.1111/jnc.15227
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15227
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Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation

1
1. scibot 18 Nov 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.molcel.2020.09.022
  
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ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription

1
1. scibot 12 Nov 2020
  
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  RRID:AB_476744
  
  DOI: 10.7554/eLife.53550
  
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Generation of the CRISPR/Cas9-mediated KIF1C knock-out human iPSC line HIHRSi003-A-1

1
1. scibot 03 Nov 2020
  
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  AB_476744
  
  DOI: 10.1016/j.scr.2020.102059
  
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Oct 2020
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Aggresome formation and liquid-liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 43

1
1. scibot 29 Oct 2020
  
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  RRID:AB_476744
  
  DOI: 10.1038/s41419-020-03116-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7585435/
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Proton extrusion during oxidative burst in microglia exacerbates pathological acidosis following traumatic brain injury

1
1. scibot 27 Oct 2020
  
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  mouse anti‐β‐actin
  
  DOI: 10.1002/glia.23926
  
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onlinelibrary.wiley.com/doi/full/10.1002/glia.23926
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Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

1
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  DOI: 10.1371/journal.ppat.1008461
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7553310/
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CMTR1-Catalyzed 2′-O-Ribose Methylation Controls Neuronal Development by Regulating Camk2α Expression Independent of RIG-I Signaling

1
1. scibot 24 Oct 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.108269
  
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cell.com/cell-reports/abstract/S2211-1247(20)31258-4
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Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo

1
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  RRID:AB_476744
  
  DOI: 10.1016/j.molmet.2020.101085
  
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sciencedirect.com/science/article/pii/S2212877820301599
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin‐induced colon epithelial cell signaling

1
1. scibot 20 Oct 2020
  
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  β‐actin
  
  DOI: 10.1096/fj.202001669R
  
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faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202001669R
mcr.aacrjournals.org mcr.aacrjournals.org

Mitochondria participate in chemoresistance to cisplatin in human ovarian cancer cells

1
1. scibot 15 Oct 2020
  
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  RRID:AB_476744
  
  DOI: 10.1158/1541-7786.MCR-19-1145
  
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mcr.aacrjournals.org/content/18/9/1379
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Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis

1
1. scibot 13 Oct 2020
  
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  RRID:AB_476744
  
  DOI: 10.7554/eLife.59442
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
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Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis

1
1. scibot 10 Oct 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.molcel.2020.09.018
  
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pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer

1
1. scibot 08 Oct 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.108231
  
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pubmed.ncbi.nlm.nih.gov/33027658/
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Interferon-λ Enhances the Differentiation of Naive B Cells into Plasmablasts via the mTORC1 Pathway

1
1. scibot 08 Oct 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.108211
  
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sciencedirect.com/science/article/pii/S2211124720312006
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Dissecting Gq/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1

1
1. scibot 03 Oct 2020
  
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  Anti-β-actin
  
  DOI: 10.3390/cells9102201
  
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pubmed.ncbi.nlm.nih.gov/33003441/
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A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways

1
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  RRID:AB_476744
  
  DOI: 10.1016/j.cmet.2020.01.011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7214782/
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A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling

1
1. scibot 26 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.03.030
  
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sciencedirect.com/science/article/pii/S2211124720303442
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Activated CX3CL1/Smad2 signals prevent neuronal loss and Alzheimer's tau pathology-mediated cognitive dysfunction

1
1. scibot 26 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1523/JNEUROSCI.1333-19.2019
  
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jneurosci.org/content/40/5/1133
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Streptococcus pneumoniae Infection Promotes Histone H3 Dephosphorylation by Modulating Host PP1 Phosphatase

1
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.02.116
  
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sciencedirect.com/science/article/pii/S2211124720302977
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Toll-like Receptor 5 Activation by the CagY Repeat Domains of Helicobacter pylori

1
1. scibot 26 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.108159
  
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sciencedirect.com/science/article/pii/S2211124720311487
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Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration

1
1. scibot 26 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.107572
  
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sciencedirect.com/science/article/pii/S2211124720305210
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AMPK Preferentially Depresses Retrograde Transport of Axonal Mitochondria during Localized Nutrient Deprivation

1
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  RRID:AB_476744
  
  DOI: 10.1523/JNEUROSCI.2067-19.2020
  
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jneurosci.org/content/40/25/4798
insight.jci.org insight.jci.org

The RNFT2/IL3Rα axis regulates IL3 signaling and innate immunity

1
1. scibot 26 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1172/jci.insight.133652
  
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insight.jci.org/articles/view/133652
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PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1

1
1. scibot 25 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1038/s41598-020-69698-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7391766/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Sex‐dimorphic effects of biogenesis of lysosome‐related organelles complex‐1 deficiency on mouse perinatal brain development

1
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  RRID:AB_476744
  
  DOI: 10.1002/jnr.24620
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24620
dev.biologists.org dev.biologists.org

Vessel-derived angiocrine IGF-1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis

1
1. scibot 25 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1242/dev.190488
  
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dev.biologists.org/content/147/11/dev190488
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The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis

1
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.108162
  
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sciencedirect.com/science/article/pii/S2211124720311517
elifesciences.org elifesciences.org

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss

1
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  RRID:AB_4767441
  
  DOI: 10.7554/eLife.39159
  
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elifesciences.org/articles/39159
elifesciences.org elifesciences.org

UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity

1
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  RRID:AB_476744
  
  DOI: 10.7554/eLife.37993
  
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elifesciences.org/articles/37993
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A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells

1
1. scibot 23 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.molcel.2020.04.022
  
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KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

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Downregulation of miR-335-5P in Amyotrophic Lateral Sclerosis Can Contribute to Neuronal Mitochondrial Dysfunction and Apoptosis

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Inhibition of Ferroptosis Alleviates Early Brain Injury After Subarachnoid Hemorrhage In Vitro and In Vivo via Reduction of Lipid Peroxidation

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Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab

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Differential song deficits after lentivirus-mediated knockdown of FoxP1, FoxP2 or FoxP4 in Area X of juvenile zebra finches

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Defining and Targeting Adaptations to Oncogenic KRASG12C Inhibition Using Quantitative Temporal Proteomics

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Shifts in Ribosome Engagement Impact Key Gene Sets in Neurodevelopment and Ubiquitination in Rett Syndrome

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Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells

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Differentiation Drives Widespread Rewiring of the Neural Stem Cell Chaperone Network

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Impairing committed cholesterol biosynthesis in white matter astrocytes, but not grey matter astrocytes, enhances in vitro myelination

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DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis

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DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State

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Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during Myelination

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SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes

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The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction

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BPS Publications

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Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism

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Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity

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A Non-Replicative Role of the 3′ Terminal Sequence of the Dengue Virus Genome in Membranous Replication Organelle Formation

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Differential regulation and targeting of estrogen receptor α turnover in invasive lobular breast carcinoma

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MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation

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BPS Publications

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AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell Synaptic Excitability and Procedural Memory Formation

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FBXW7 Confers Radiation Survival by Targeting p53 for Degradation

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Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis

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NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesisNCAM regulates temporal NPC specification

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Ciliary melanin‐concentrating hormone receptor 1 (MCHR1) is widely distributed in the murine CNS in a sex‐independent manner

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NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay

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Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination

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Dynamic regulation of NADPH oxidase 5 by intracellular heme levels and cellular chaperones

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A human minisatellite hosts an alternative transcription start site for NPRL3 driving its expression in a repeat number‐dependent manner

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onlinelibrary.wiley.com/doi/10.1002/humu.23974
www.embopress.org www.embopress.org

Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia‐like phenotypes in mice

1
1. scibot 08 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.15252/embj.2018101090
  
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embopress.org/doi/abs/10.15252/embj.2018101090
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Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells

1
1. scibot 08 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.108013
  
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sciencedirect.com/science/article/pii/S2211124720309980
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Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription

1
1. scibot 08 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.molcel.2020.01.008
  
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sciencedirect.com/science/article/pii/S1097276520300083
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Human Bone Marrow Is Comprised of Adipocytes with Specific Lipid Metabolism

1
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2019.12.089
  
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sciencedirect.com/science/article/pii/S2211124719317541
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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

1
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.107764
  
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sciencedirect.com/science/article/pii/S2211124720307440
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Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice

1
1. scibot 07 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.cmet.2020.01.012
  
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sciencedirect.com/science/article/pii/S1550413120300139
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Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans

1
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2019.12.078
  
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sciencedirect.com/science/article/pii/S2211124719317437
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

1
1. scibot 06 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.7554/eLife.54877
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7185992/
www.cell.com www.cell.com

PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers

1
1. scibot 06 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.cmet.2018.09.002
  
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cell.com/cell-metabolism/abstract/S1550-4131(18)30567-9
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Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development

1
1. scibot 05 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1016/j.devcel.2020.04.009
  
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sciencedirect.com/science/article/pii/S1534580720303075
onlinelibrary.wiley.com onlinelibrary.wiley.com

Melatonin alters neuronal architecture and increases cysteine‐rich protein 1 signaling in the male mouse hippocampus

1
1. scibot 05 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1002/jnr.24708
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24708
www.cell.com www.cell.com

Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia

1
1. scibot 04 Sep 2020
  
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  RRID: AB_476744
  
  DOI: 10.1016/j.celrep.2018.09.057
  
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cell.com/cell-reports/fulltext/S2211-1247(18)31502-X
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An Allosteric Interaction Network Promotes Conformation State-Dependent Eviction of the Nas6 Assembly Chaperone from Nascent 26S Proteasomes

1
1. scibot 04 Sep 2020
  
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  RRID: AB_476744
  
  DOI: 10.1016/j.celrep.2018.12.042
  
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cell.com/cell-reports/fulltext/S2211-1247(18)31972-7
link.springer.com link.springer.com

Prostaglandin E2 receptor 3 (EP3) signaling promotes migration of cervical cancer via urokinase-type plasminogen activator receptor (uPAR)

1
1. scibot 04 Sep 2020
  
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  mouse monoclonal anti-β-actin
  
  DOI: 10.1007/s00432-020-03272-0
  
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link.springer.com/article/10.1007/s00432-020-03272-0
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The Leucine-Rich Repeat Region of CARMIL1 Regulates IL-1-Mediated ERK Activation, MMP Expression, and Collagen Degradation

1
1. scibot 04 Sep 2020
  
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  Mouse monoclonal anti-β-actin
  
  DOI: 10.1016/j.celrep.2020.107781
  
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sciencedirect.com/science/article/pii/S2211124720307610
www.mdpi.com www.mdpi.com

Merkel Cell Polyomavirus T Antigens Induce Merkel Cell-Like Differentiation in GLI1-Expressing Epithelial Cells

1
1. scibot 04 Sep 2020
  
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  Actin
  
  DOI: 10.3390/cancers12071989
  
  Resource: (Sigma-Aldrich Cat# A5441, RRID:AB_476744)
  
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mdpi.com/2072-6694/12/7/1989
onlinelibrary.wiley.com onlinelibrary.wiley.com

Alpha‐ and Beta‐Tubulin Isotypes are Differentially Expressed during Brain Development

1
1. scibot 04 Sep 2020
  
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  mouse anti‐beta‐actin
  
  DOI: 10.1002/dneu.22745
  
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onlinelibrary.wiley.com/doi/10.1002/dneu.22745
onlinelibrary.wiley.com onlinelibrary.wiley.com

Next‐generation sequencing reveals a novel role of lysine‐specific demethylase 1 in adhesion of rhabdomyosarcoma cells

1
1. scibot 04 Sep 2020
  
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  mouse anti‐β‐Actin
  
  DOI: 10.1002/ijc.32806
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32806
onlinelibrary.wiley.com onlinelibrary.wiley.com

Biomarker Profile for Prediction of Response to SMAC Mimetic Monotherapy in Pediatric Precursor B‐Cell Acute Lymphoblastic Leukemia

1
1. scibot 04 Sep 2020
  
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  Actin
  
  DOI: 10.1002/ijc.32799
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32799
learn.dcollege.net learn.dcollege.net

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

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  RRID:AB_476744
  
  DOI: 10.1016/j.cell.2020.02.052
  
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learn.dcollege.net/bbcswebdav/xid-417401817_1
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Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells

1
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  RRID:AB_476744
  
  DOI: 10.1016/j.celrep.2020.107715
  
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sciencedirect.com/science/article/pii/S2211124720306926
www.nature.com www.nature.com

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

1
1. scibot 03 Sep 2020
  
  in Public
  
  anti β-actin
  
  DOI: 10.1038/s41589-019-0424-1
  
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nature.com/articles/s41589-019-0424-1
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IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway

1
1. scibot 03 Sep 2020
  
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  Mouse anti-β-actin
  
  DOI: 10.3390/cells9010147
  
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mdpi.com/2073-4409/9/1/147
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Generation of OCT4-EGFP, NANOG-tdTomato dual reporter human induced pluripotent stem cell line, KKUi001-A, using the CRISPR/Cas9 system

1
1. scibot 03 Sep 2020
  
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  Mouse monoclonal anti-β-Actin
  
  DOI: 10.1016/j.scr.2020.101943
  
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sciencedirect.com/science/article/pii/S1873506120302440
link.springer.com link.springer.com

PKCγ-Mediated Phosphorylation of CRMP2 Regulates Dendritic Outgrowth in Cerebellar Purkinje Cells

1
1. scibot 03 Sep 2020
  
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  mouse anti-actin
  
  DOI: 10.1007/s12035-020-02038-6
  
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link.springer.com/article/10.1007/s12035-020-02038-6
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CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival

1
1. scibot 03 Sep 2020
  
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  A5441
  
  DOI: 10.1016/j.celrep.2020.107815
  
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sciencedirect.com/science/article/pii/S2211124720307968
elifesciences.org elifesciences.org

FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences

1
1. scibot 03 Sep 2020
  
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  anti-beta-actin
  
  DOI: 10.7554/eLife.52621
  
  Resource: (Sigma-Aldrich Cat# A5441, RRID:AB_476744)
  
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elifesciences.org/articles/52621
europepmc.org europepmc.org

Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

1
1. scibot 03 Sep 2020
  
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  AB_476744
  
  DOI: 10.1371/journal.pbio.3000411
  
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europepmc.org/article/MED/32663221
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BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells

1
1. scibot 03 Sep 2020
  
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  RRID:AB_476744
  
  DOI: 10.1038/s41419-020-2589-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7235254/

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