1,096 Matching Annotations
  1. Sep 2020
  2. www.mdpi.com www.mdpi.com
    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
    1
    1. scibot 03 Sep 2020
      Mouse anti-β-actin

      DOI: 10.3390/cells9010147

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    mdpi.com/2073-4409/9/1/147
  3. www.sciencedirect.com www.sciencedirect.com
    Generation of OCT4-EGFP, NANOG-tdTomato dual reporter human induced pluripotent stem cell line, KKUi001-A, using the CRISPR/Cas9 system
    1
    1. scibot 03 Sep 2020
      Mouse monoclonal anti-β-Actin

      DOI: 10.1016/j.scr.2020.101943

      Resource: (Sigma-Aldrich Cat# A5441, RRID:AB_476744)

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    sciencedirect.com/science/article/pii/S1873506120302440
  4. link.springer.com link.springer.com
    PKCγ-Mediated Phosphorylation of CRMP2 Regulates Dendritic Outgrowth in Cerebellar Purkinje Cells
    1
    1. scibot 03 Sep 2020
      mouse anti-actin

      DOI: 10.1007/s12035-020-02038-6

      Resource: (Sigma-Aldrich Cat# A5441, RRID:AB_476744)

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    link.springer.com/article/10.1007/s12035-020-02038-6
  5. www.sciencedirect.com www.sciencedirect.com
    CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival
    1
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      A5441

      DOI: 10.1016/j.celrep.2020.107815

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    sciencedirect.com/science/article/pii/S2211124720307968
  6. elifesciences.org elifesciences.org
    FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences
    1
    1. scibot 03 Sep 2020
      anti-beta-actin

      DOI: 10.7554/eLife.52621

      Resource: (Sigma-Aldrich Cat# A5441, RRID:AB_476744)

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    elifesciences.org/articles/52621
  7. europepmc.org europepmc.org
    Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
    1
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      AB_476744

      DOI: 10.1371/journal.pbio.3000411

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    europepmc.org/article/MED/32663221
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
    1
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      RRID:AB_476744

      DOI: 10.1038/s41419-020-2589-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC7235254/
  9. www.sciencedirect.com www.sciencedirect.com
    RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling
    1
    1. scibot 03 Sep 2020
      RRID:AB_476744

      DOI: 10.1016/j.celrep.2020.108002

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    sciencedirect.com/science/article/pii/S2211124720309876
  10. www.sciencedirect.com www.sciencedirect.com
    Intersectin-Mediated Clearance of SNARE Complexes Is Required for Fast Neurotransmission
    1
    1. scibot 03 Sep 2020
      RRID:AB_476744

      DOI: 10.1016/j.celrep.2019.12.035

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    sciencedirect.com/science/article/pii/S2211124719316924
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer
    1
    1. scibot 01 Sep 2020
      RRID:AB_476744

      DOI: 10.7554/eLife.58810

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    ncbi.nlm.nih.gov/pmc/articles/PMC7447441/
  12. Aug 2020
  13. link.springer.com link.springer.com
    The Laminin-Induced Phosphorylation of PKCδ Regulates AQP4 Distribution and Water Permeability in Rat Astrocytes
    1
    1. scibot 28 Aug 2020
      RRID:AB_476744

      DOI: 10.1007/s10571-020-00944-w

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    link.springer.com/article/10.1007/s10571-020-00944-w
  14. Jan 2020
  15. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1016/j.devcel.2019.07.010

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      RRID:AB_476744 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580719305829
  16. www.jneurosci.org www.jneurosci.org
    AMPA Receptor Dysregulation and Therapeutic Interventions in a Mouse Model of CDKL5 Deficiency Disorder
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1523/JNEUROSCI.2041-18.2019

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    jneurosci.org/content/39/24/4814
  17. www.mdpi.com www.mdpi.com
    Corticosterone Upregulates Gene and Protein Expression of Catecholamine Markers in Organotypic Brainstem Cultures
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.3390/ijms20122901

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    mdpi.com/1422-0067/20/12/2901/htm
  18. elifesciences.org elifesciences.org
    Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.7554/eLife.45873

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    elifesciences.org/articles/45873
  19. www.sciencedirect.com www.sciencedirect.com
    AGO CLIP Reveals an Activated Network for Acute Regulation of Brain Glutamate Homeostasis in Ischemic Stroke
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1016/j.celrep.2019.06.075

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    sciencedirect.com/science/article/pii/S2211124719308551
  20. www.sciencedirect.com www.sciencedirect.com
    The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1016/j.cell.2019.07.031

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    sciencedirect.com/science/article/pii/S009286741930830X
  21. www.jbc.org www.jbc.org
    The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1074/jbc.AC119.010671

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    jbc.org/content/294/45/16527.full
  22. www.cell.com www.cell.com
    Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1016/j.cell.2019.06.001

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    cell.com/cell/fulltext/S0092-8674(19)30629-4
  23. academic.oup.com academic.oup.com
    Synergistic Highly Potent Targeted Drug Combinations in different Pheochromocytoma Models including Human Tumor Cultures
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1210/en.2019-00410

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      RRID:AB_476744 RRIDCUR:Validated
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    academic.oup.com/endo/article/160/11/2600/5535649
  24. www.sciencedirect.com www.sciencedirect.com
    Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1016/j.immuni.2019.10.002

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      RRID:AB_476744 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319304467
  25. www.sciencedirect.com www.sciencedirect.com
    TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1016/j.celrep.2019.07.036

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    sciencedirect.com/science/article/pii/S2211124719309337
  26. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1111/bph.14794

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14794
  27. www.nature.com www.nature.com
    Sp1-regulated expression of p11 contributes to motor neuron degeneration by membrane insertion of TASK1
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1038/s41467-019-11637-4

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    nature.com/articles/s41467-019-11637-4
  28. www.sciencedirect.com www.sciencedirect.com
    Induction of an Alternative mRNA 5′ Leader Enhances Translation of the Ciliopathy Gene Inpp5e and Resistance to Oncolytic Virus Infection
    1
    1. scibot 13 Jan 2020
      AB_476744

      DOI: 10.1016/j.celrep.2019.11.072

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    sciencedirect.com/science/article/pii/S2211124719315633
  29. link.springer.com link.springer.com
    Expression of Phospho-MeCP2s in the Developing Rat Brain and Function of Postnatal MeCP2 in Cerebellar Neural Cell Development
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1007/s12264-016-0086-x

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    link.springer.com/article/10.1007/s12264-016-0086-x
  30. www.sciencedirect.com www.sciencedirect.com
    The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
    2
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      RRID:AB_476744

      DOI: 10.1016/j.celrep.2019.09.032

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      RRID:AB_476744 RRIDCUR:Validated
    2. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1016/j.celrep.2019.09.032

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    sciencedirect.com/science/article/pii/S2211124719312203
  31. www.sciencedirect.com www.sciencedirect.com
    CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1016/j.ccell.2019.11.003

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    sciencedirect.com/science/article/pii/S1535610819305239
  32. www.sciencedirect.com www.sciencedirect.com
    Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB
    1
    1. scibot 13 Jan 2020
      RRID:AB_476744

      DOI: 10.1016/j.molcel.2019.11.008

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    sciencedirect.com/science/article/pii/S1097276519308378
  33. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Diethyldithiocarbamate, an anti‐abuse drug, alleviates steatohepatitis and fibrosis in rodents through modulating lipid metabolism and oxidative stress
    2
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      RRID:AB_476744

      DOI: 10.1111/bph.14503

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      RRID:AB_476744

      DOI: 10.1111/bph.14503

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14503
  34. www.sciencedirect.com www.sciencedirect.com
    TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation
    1
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      DOI: 10.1016/j.celrep.2019.05.040

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    sciencedirect.com/science/article/pii/S2211124719306606
  35. www.sciencedirect.com www.sciencedirect.com
    LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion
    1
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      DOI: 10.1016/j.celrep.2019.11.063

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    sciencedirect.com/science/article/pii/S2211124719315542
  36. www.sciencedirect.com www.sciencedirect.com
    The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma
    1
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      DOI: 10.1016/j.celrep.2019.05.069

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    sciencedirect.com/science/article/pii/S2211124719306989
  37. www.sciencedirect.com www.sciencedirect.com
    Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
    1
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      DOI: 10.1016/j.cmet.2019.09.009

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    sciencedirect.com/science/article/pii/S1550413119305121
  38. www.sciencedirect.com www.sciencedirect.com
    CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity
    1
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      DOI: 10.1016/j.cell.2019.05.008

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    sciencedirect.com/science/article/pii/S0092867419305069
  39. www.sciencedirect.com www.sciencedirect.com
    Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2
    1
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      DOI: 10.1016/j.celrep.2019.08.087

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    sciencedirect.com/science/article/pii/S2211124719311490
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    Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade
    1
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      DOI: 10.1016/j.devcel.2019.11.012

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    sciencedirect.com/science/article/pii/S1534580719309438
  41. www.sciencedirect.com www.sciencedirect.com
    Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells
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    Neuronal Ca2+‐dependent activator protein 1 (NCDAP1) induces neuronal cell death by activating p53 pathway following traumatic brain injury
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    Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis
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    Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer
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    Class-Switch Recombination Occurs Infrequently in Germinal Centers
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    SRXN1 is Necessary for Resolution of GnRH-induced Oxidative Stress and Induction of Gonadotropin Gene Expression
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    Motor Neurons Pathology After Chronic Exposure to MPTP in Mice
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    Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior
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    Hepatic HKDC1 Expression Contributes to Liver Metabolism
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    Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome
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    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
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    VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells
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    Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis
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    Roseburia Spp. Abundance Associates with Alcohol Consumption in Humans and Its Administration Ameliorates Alcoholic Fatty Liver in Mice
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    Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity
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    Neuronal NLRC5 regulates MHC class Ⅰ expression in Neuro‐2a cells and also during hippocampal development
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    Spatiotemporal Coupling of the Hepatitis C Virus Replication Cycle by Creating a Lipid Droplet- Proximal Membranous Replication Compartment
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    Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility
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    The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling
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    Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome
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    Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation
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    Tanycytes Regulate Lipid Homeostasis by Sensing Free Fatty Acids and Signaling to Key Hypothalamic Neuronal Populations via FGF21 Secretion
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    Generation of a genetically modified human embryonic stem cells expressing fluorescence tagged ATOX1
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    Risperidone ameliorates prefrontal cortex neural atrophy and oxidative/nitrosative stress in brain and peripheral blood of rats with neonatal ventral hippocampus lesion
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    Syndecan-1 Mediates Sorting of Soluble Lipoprotein Lipase with Sphingomyelin-Rich Membrane in the Golgi Apparatus
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    Melatonin-mediated downregulation of thymidylate synthase as a novel mechanism for overcoming 5-fluorouracil associated chemoresistance in colorectal cancer cells
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    TSPYL5 Depletion Induces Specific Death of ALT Cells through USP7-Dependent Proteasomal Degradation of POT1
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    Effects of sleep disruption on stress, nigrostriatal markers, and behavior in a chronic/progressive MPTP male mouse model of parkinsonism
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    Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis
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    A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering
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    Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1−Akt signaling pathway
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    Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis
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    ADAM17-dependent signaling is required for oncogenic human papillomavirus entry platform assembly
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    Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets
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    The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance
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    TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer
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    Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
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    Dihydrotestosterone increases cytotoxic activity of macrophages on prostate cancer cells via TRAIL
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    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model
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    GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis
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    Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism
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    Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies
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    The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4
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    Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan
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  163. www.sciencedirect.com www.sciencedirect.com
    An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication
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    Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import
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    Gastrodin attenuates microglia activation through renin-angiotensin system and Sirtuin3 pathway
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    Conventional and Neo-Antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors
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  167. academic.oup.com academic.oup.com
    SAD-A Promotes Glucose-stimulated Insulin Secretion through Phosphorylation and Inhibition of GDIα in Male Islet β-cells
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity
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    Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State
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    Mapping the Genetic Landscape of Human Cells
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    Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma
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    Simultaneous Ablation of Neuronal Neurofascin and Ankyrin G in Young and Adult Mice Reveals Age-Dependent Increase in Nodal Stability in Myelinated Axons and Differential Effects on the Lifespan
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    High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration
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    By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation
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    Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
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    APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
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  182. www.jneurosci.org www.jneurosci.org
    NPY Induces Stress Resilience via Downregulation of Ih in Principal Neurons of Rat Basolateral Amygdala
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    Tissue Damage Signaling Is a Prerequisite for Protective Neutrophil Recruitment to Microbial Infection in Zebrafish
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  184. elifesciences.org elifesciences.org
    Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations
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    N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response
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  186. elifesciences.org elifesciences.org
    VEGF signaling regulates the fate of obstructed capillaries in mouse cortex
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    Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models
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    Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover
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    The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma
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    Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14310
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    N-Acetyl Cysteine Functions as a Fast-Acting Antioxidant by Triggering Intracellular H2S and Sulfane Sulfur Production
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    Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength
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  195. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The ameliorative effect of fluoxetine on neuroinflammation induced by sleep deprivation
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    lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation
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    Modest enhancement of sensory axon regeneration in the sciatic nerve with conditional co-deletion of PTEN and SOCS3 in the dorsal root ganglia of adult mice
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    Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1‐linked amyotrophic lateral sclerosis mice
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