941 Matching Annotations
  1. Jan 2020
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    USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification
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      DOI: 10.1016/j.celrep.2019.06.083

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    C9-ALS/FTD-linked proline–arginine dipeptide repeat protein associates with paraspeckle components and increases paraspeckle formation
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      DOI: 10.1038/s41419-019-1983-5

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    Profilin and formin constitute a pacemaker system for robust actin filament growth
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    miR-29a/b1 Inhibits Hair Follicle Stem Cell Lineage Progression by Spatiotemporally Suppressing WNT and BMP Signaling
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    Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice
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    Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis
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    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
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    PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin
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    MicroRNA-1-Mediated Inhibition of Cardiac Fibroblast Proliferation Through Targeting Cyclin D2 and CDK6
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      DOI: 10.3389/fcvm.2019.00065

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    Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity
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    sciencedirect.com/science/article/pii/S0960982219309327
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    Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors
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    ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus
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    AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration
    1
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      DOI: 10.1016/j.stem.2019.10.011

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    Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.
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    Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention
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      DOI: 10.1016/j.ccell.2019.08.001

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    A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia
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    Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
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    Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion
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      DOI: 10.7554/eLife.45789

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    Paradoxical Role for Wild-Type p53 in Driving Therapy Resistance in Melanoma
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      DOI: 10.1016/j.molcel.2019.11.009

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    Exploring Targeted Degradation Strategy for Oncogenic KRASG12C
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      DOI: 10.1016/j.chembiol.2019.12.006

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    sciencedirect.com/science/article/pii/S2451945619304027
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    AUTACs: Cargo-Specific Degraders Using Selective Autophagy
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      DOI: 10.1016/j.molcel.2019.09.009

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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
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      DOI: 10.7554/eLife.46840

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    Myogenic vasoconstriction requires G12/G13 and LARG to maintain local and systemic vascular resistance
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      DOI: 10.7554/eLife.49374

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    CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells
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    Inhibition of sirtuin 1 deacetylase by miR-211-5p provides a mechanism for the induction of cell death in breast cancer cells
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      DOI: 10.1016/j.gene.2019.06.029

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    Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies
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    Abnormal Striatal Development Underlies the Early Onset of Behavioral Deficits in Shank3B−/− Mice
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    WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis
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    IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners
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      DOI: 10.1038/s41467-019-12318-y

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    Induced pluripotent stem cells (iPSCs) derived from a Renpenning Syndrome Patient with c.459_462delAGAG Mutation in PQBP1 (PEIi001-A)
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    The lncRNA SLNCR Recruits the Androgen Receptor to EGR1-Bound Genes in Melanoma and Inhibits Expression of Tumor Suppressor p21
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    Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging
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      DOI: 10.18632/aging.101655

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    Norepinephrine protects against apoptosis of mesenchymal stem cells induced by high glucose
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      DOI: 10.1002/jcp.28686

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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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    Inactivation of endothelial adenosine A2A receptors protects mice from cerebral ischaemia‐induced brain injury
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      DOI: 10.1111/bph.14673

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      DOI: 10.1210/en.2018-00887

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    Mutations in Craniosynostosis Patients Cause Defective Interleukin-11 Receptor Maturation and Drive Craniosynostosis-like Disease in Mice
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    A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 Inflammasome
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    A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases
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    Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
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    Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors
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    Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain
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    Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology
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    Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models
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    Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice
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    Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells
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    The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins
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    Synapsin I deletion reduces neuronal damage and ameliorates clinical progression of experimental autoimmune encephalomyelitis
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    Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue
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    Aldose Reductase Mediates NLRP3 Inflammasome–Initiated Innate Immune Response in Hyperglycemia-Induced Thp1 Monocytes and Male Mice
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    Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages
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    An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation
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    Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma
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      Curator: @Jmenke

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  125. www.sciencedirect.com www.sciencedirect.com
    A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons
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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0896627317306001
  126. www.sciencedirect.com www.sciencedirect.com
    A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45
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    sciencedirect.com/science/article/pii/S1097276517304586
  127. elifesciences.org elifesciences.org
    Chronic lithium treatment elicits its antimanic effects via BDNF-TrkB dependent synaptic downscaling
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    elifesciences.org/articles/25480
  128. www.sciencedirect.com www.sciencedirect.com
    TERRA RNA Antagonizes ATRX and Protects Telomeres
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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0092867417307006
  129. www.sciencedirect.com www.sciencedirect.com
    SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs
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  130. www.sciencedirect.com www.sciencedirect.com
    Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
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      Curator: @chewbeccax

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  131. www.sciencedirect.com www.sciencedirect.com
    Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics
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      Curator: @Zeljana_Babic

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  132. www.sciencedirect.com www.sciencedirect.com
    RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health
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  133. academic.oup.com academic.oup.com
    Aberrant TGF-β Signaling Drives Castration-Resistant Prostate Cancer in a Male Mouse Model of Prostate Tumorigenesis
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      Curator: @bandrow

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  134. elifesciences.org elifesciences.org
    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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      Curator: @kaitlinsung

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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis
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  136. www.sciencedirect.com www.sciencedirect.com
    Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages
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      Curator: @Zeljana_Babic

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  137. www.sciencedirect.com www.sciencedirect.com
    Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a
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  138. www.jneurosci.org www.jneurosci.org
    Activation of Group II Metabotropic Glutamate Receptors Promotes LTP Induction at Schaffer Collateral-CA1 Pyramidal Cell Synapses by Priming NMDA Receptors
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      Curator: @chewbeccax

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    jneurosci.org/content/36/45/11521
  139. www.jneurosci.org www.jneurosci.org
    Untitled document
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    jneurosci.org/content/36/45/11521.full
  140. www.sciencedirect.com www.sciencedirect.com
    Interleukin-17A mediates cardiomyocyte apoptosis through Stat3-iNOS pathway
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      Curator: @kaitlinsung

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    sciencedirect.com/science/article/pii/S016748891630218X
  141. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ouabain‐induced changes in MAP kinase phosphorylation in primary culture of rat cerebellar cells
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      Curator: @gabimpine

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    onlinelibrary.wiley.com/doi/10.1002/cbf.3199/full
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Application of ARID1A to murine formalin-fixed paraffin embedded tissue using immunohistochemistry
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      Curator: @jcabotaj

      Curator note: Table

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    ncbi.nlm.nih.gov/pmc/articles/PMC4304311/