6,481 Matching Annotations
  1. Mar 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Neuromuscular organoids model spinal neuromuscular pathologies in C9orf72 amyotrophic lateral sclerosis
    1
    1. scibot 05 Mar 2024
      RRID:SCR_003070

      DOI: 10.1016/j.celrep.2024.113892

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    sciencedirect.com/science/article/pii/S2211124724002201
  3. www.sciencedirect.com www.sciencedirect.com
    Engineered CBEs based on Macaca fascicularis A3A with improved properties for precise genome editing
    1
    1. scibot 05 Mar 2024
      SCR_003070

      DOI: 10.1016/j.celrep.2024.113878

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    sciencedirect.com/science/article/pii/S2211124724002067
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of adult hippocampal neural stem cells occurs in the early postnatal dentate gyrus and depends on cyclin D2
    1
    1. scibot 03 Mar 2024
      SCR_003070

      DOI: 10.1038/s44318-023-00011-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897295/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression
    1
    1. scibot 03 Mar 2024
      RRID:SCR_003070

      DOI: 10.1158/1078-0432.CCR-23-0749

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    ncbi.nlm.nih.gov/pmc/articles/PMC10528807/
  6. www.sciencedirect.com www.sciencedirect.com
    PBRM1 presents a potential ctDNA marker to monitor response to neoadjuvant chemotherapy in cervical cancer
    1
    1. scibot 02 Mar 2024
      RRID:SCR_003070

      DOI: 10.1016/j.isci.2024.109160

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    sciencedirect.com/science/article/pii/S258900422400381X
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer-associated fibroblast-specific expression of the matricellular protein CCN1 coordinates neovascularization and stroma deposition in melanoma metastasis
    1
    1. scibot 02 Mar 2024
      RRID:SCR_003070

      DOI: 10.1158/2767-9764.CRC-23-0571

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    ncbi.nlm.nih.gov/pmc/articles/PMC10898341/
  8. Feb 2024
  9. journals.physiology.org journals.physiology.org
    The matricellular protein CCN3 supports lung endothelial homeostasis and function
    1
    1. scibot 29 Feb 2024
      RRID: SCIR_003070

      DOI: 10.1152/ajplung.00248.2022

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    journals.physiology.org/doi/full/10.1152/ajplung.00248.2022
  10. www.sciencedirect.com www.sciencedirect.com
    Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development
    1
    1. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.1016/j.isci.2024.109180

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    sciencedirect.com/science/article/pii/S2589004224004012
  11. www.sciencedirect.com www.sciencedirect.com
    Chronic Rapamycin administration via drinking water mitigates the pathological phenotype in a Krabbe disease mouse model through autophagy activation
    2
    1. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.1016/j.biopha.2024.116351

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    2. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.1016/j.biopha.2024.116351

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    sciencedirect.com/science/article/pii/S075333222400235X
  12. www.biorxiv.org www.biorxiv.org
    Monosynaptically-interconnected Network Module (MNM) Approach for High-Resolution Brain Sub-Network Analysis
    1
    1. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.1101/2024.02.19.581007

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    biorxiv.org/content/10.1101/2024.02.19.581007v1
  13. www.biorxiv.org www.biorxiv.org
    Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson’s Disease
    1
    1. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.1101/2024.02.19.580982

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    biorxiv.org/content/10.1101/2024.02.19.580982v1
  14. journals.sagepub.com journals.sagepub.com
    Hemorrhagic stroke-induced subtype of inflammatory reactive astrocytes disrupts blood-brain barrier
    1
    1. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.1177/0271678X241235008

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    journals.sagepub.com/doi/10.1177/0271678X241235008
  15. www.mdpi.com www.mdpi.com
    Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum
    1
    1. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.3390/cells13050386

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    mdpi.com/2073-4409/13/5/386
  16. 52.53.155.43 52.53.155.43
    d7-html.html
    1
    1. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1541-7786.mcr-23-0414

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    52.53.155.43/285da8d6b2daddbb90f8efe2aa1fe882a90d6c3e/d7-html.html
  17. 52.53.155.43 52.53.155.43
    delete 6-html.html
    1
    1. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1078-0432.ccr-23-2094

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    52.53.155.43/1c1e4424f97ee7adb8835ca35dec2b9e6e988f80/delete 6-html.html
  18. 52.53.155.43 52.53.155.43
    JNEUROSCI.0963-22.2024.full-html.html
    1
    1. scibot 29 Feb 2024
      RRID:SCR_003070

      DOI: 10.1523/jneurosci.0963-22.2024

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    52.53.155.43/b473d76b79f8198a49be47494ae44dc8ff2608ab/JNEUROSCI.0963-22.2024.full-html.html
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation
    1
    1. scibot 28 Feb 2024
      RRID:SCR_003070

      DOI: 10.3389/fcell.2024.1297116

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    ncbi.nlm.nih.gov/pmc/articles/PMC10883382/
  20. www.jneurosci.org www.jneurosci.org
    EHBP1 is critically involved in dendritic arbor formation and is coupled to factors promoting actin filament formation
    1
    1. scibot 28 Feb 2024
      RRID:SCR_003070

      DOI: 10.1523/JNEUROSCI.0236-23.2023

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    jneurosci.org/content/44/6/e0236232023
  21. 52.53.155.43 52.53.155.43
    Carotid Body Function in Tyrosine Hydroxylase Conditional Olfr78 Knockout Mice
    1
    1. scibot 28 Feb 2024
      RRID:SCR_0

      DOI: 10.1093/function/zqae010

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    52.53.155.43/0c292ec464a8f63d65d4d20c336506a1f77fe426/zqae010-html.html
  22. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
    1
    1. scibot 27 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/2767-9764.CRC-23-0308

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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  23. 52.53.155.43 52.53.155.43
    cd-23-0954-html.html
    1
    1. scibot 27 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/2159-8290.cd-23-0954

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    52.53.155.43/aaf525c30ae01b53e260240fad732783dfb4bbac/cd-23-0954-html.html
  24. www.sciencedirect.com www.sciencedirect.com
    Extracellular lactate as an alternative energy source for retinal bipolar cells
    2
    1. scibot 27 Feb 2024
      RRID:SCR_003070

      DOI: 10.1016/j.jbc.2024.106794

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    2. scibot 27 Feb 2024
      RRID:SCR_003070

      DOI: 10.1016/j.jbc.2024.106794

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    sciencedirect.com/science/article/pii/S0021925824012675
  25. aacrjournals.org aacrjournals.org
    Mitochondrial translocase TOMM22 is overexpressed in pancreatic cancer and promotes aggressive growth by modulating mitochondrial protein import and function
    1
    1. scibot 24 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1541-7786.MCR-23-0138

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    aacrjournals.org/mcr/article/22/2/197/733695/Mitochondrial-Translocase-TOMM22-Is-Overexpressed
  26. aacrjournals.org aacrjournals.org
    A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models
    1
    1. scibot 24 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1535-7163.MCT-22-0681

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    aacrjournals.org/mct/article/23/1/3/732154/A-Novel-Irreversible-TEAD-Inhibitor-SWTX-143
  27. aacrjournals.org aacrjournals.org
    A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients
    1
    1. scibot 24 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1078-0432.CCR-23-2005

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    aacrjournals.org/clincancerres/article/29/24/5047/731678/A-Phase-I-Expansion-Cohort-Study-Evaluating-the
  28. aacrjournals.org aacrjournals.org
    Spatial transcriptomics suggests that alterations occur in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers
    1
    1. scibot 24 Feb 2024
      RRID:SCR_00370

      DOI: 10.1158/1541-7786.MCR-23-0489

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    aacrjournals.org/mcr/article/22/2/169/733690/Spatial-Transcriptomics-Suggests-That-Alterations
  29. 52.53.155.43 52.53.155.43
    can-23-1038-html.html
    3
    1. scibot 23 Feb 2024
      RRID: SCR_003070

      DOI: 10.1158/0008-5472.can-23-1038

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    2. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/0008-5472.can-23-1038

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    3. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/0008-5472.can-23-1038

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    52.53.155.43/52e7b37fca465450e68864b868e33c5f6d45d858/84-html.html
  30. aacrjournals.org aacrjournals.org
    Selective DNA-PK inhibition enhances chemotherapy and ionizing radiation activity in soft-tissue sarcomas
    1
    1. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1078-0432.CCR-23-1531

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    aacrjournals.org/clincancerres/article/30/3/629/733549/Selective-DNA-PK-Inhibition-Enhances-Chemotherapy
  31. 52.53.155.43 52.53.155.43
    Metabolic constraints on growth explain how developmental temperature scales synaptic connectivity relevant for behavior
    1
    1. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1101/2023.10.15.562389

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    52.53.155.43/cf15c57c2ff4a4b28bbe9fcac4bab08a7abf601a/2023.10.15.562389v1.full-html.html
  32. aacrjournals.org aacrjournals.org
    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
    2
    1. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1078-0432.CCR-23-1143

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    2. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1078-0432.CCR-23-1143

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    aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
  33. aacrjournals.org aacrjournals.org
    Aneuploidy Landscape in Precursors of Ovarian Cancer
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1158/1078-0432.CCR-23-0932

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    aacrjournals.org/clincancerres/article/30/3/600/733545/Aneuploidy-Landscape-in-Precursors-of-Ovarian
  34. aacrjournals.org aacrjournals.org
    Inhibition of PORCN blocks Wnt signaling to attenuate progression of oral carcinogenesis
    2
    1. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1078-0432.CCR-23-0318

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    2. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/1078-0432.CCR-23-0318

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    aacrjournals.org/clincancerres/article/30/1/209/732066/Inhibition-of-PORCN-Blocks-Wnt-Signaling-to
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1158/0008-5472.CAN-23-3239

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    ncbi.nlm.nih.gov/pmc/articles/PMC10922727/
  36. aacrjournals.org aacrjournals.org
    TEAD Inhibition Overcomes YAP1/TAZ-driven Primary and Acquired Resistance to KRASG12C Inhibitors
    2
    1. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/0008-5472.CAN-23-2994

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    2. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/0008-5472.CAN-23-2994

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    aacrjournals.org/cancerres/article/83/24/4112/731546/TEAD-Inhibition-Overcomes-YAP1-TAZ-Driven-Primary
  37. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
    3
    1. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/0008-5472.can-23-0555

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    2. scibot 23 Feb 2024
      RRID:SCR_003070

      DOI: 10.1158/0008-5472.can-23-0555

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    Midbrain neurons important for the production of mouse ultrasonic vocalizations are not required for distress calls
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    Ultrasound-Targeted Microbubble Technology Facilitates SAHH Gene Delivery to Treat Diabetic Cardiomyopathy by Activating AMPK/FOXO3/SIRT3 Signaling
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    Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
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    Growth-suppressor microRNAs mediate synaptic overgrowth and behavioral deficits in Fragile X mental retardation protein deficiency
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    Pdgfrβ is required for embryonic specification and confinement of the adult white adipose lineage
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    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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    HURP facilitates spindle assembly by stabilizing microtubules and working synergistically with TPX2
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    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease
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    SPOP negatively regulates mTORC1 activity by ubiquitinating Sec13
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    Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants
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    Overexpression and knockdown of cotton GhdadD gene reveals its drought and salt stress tolerance role
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    Protocol for image-based small-molecule screen to identify neuroprotective compounds for dopaminergic neurons in zebrafish
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    A comparative evaluation of the strengths and potential caveats of the microglial inducible CreER mouse models
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    Preclinical and Clinical Observations Implying Combination Therapy to Enhance the Efficacy of the Her-2/neu B-Cell Peptide-Based Vaccine HER-Vaxx and to Prevent Immune Evasion
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    Examining memory linking and generalization using scFLARE2, a temporally precise neuronal activity tagging system
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    NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy
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    The Oncolytic Activity of Zika Viral Therapy in Human Neuroblastoma In Vivo Models Confers a Major Survival Advantage in a CD24-dependent Manner
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    Two-Step Actions of Testicular Androgens in the Organization of a Male-Specific Neural Pathway from the Medial Preoptic Area to the Ventral Tegmental Area for Modulating Sexually Motivated Behavior
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    Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo
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    Cadmium promotes the binding and centrosomal translocation of CCDC85C and PLK4 via ROS-GCLM pathway to trigger centrosome amplification in colon cancer cells
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    Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson’s Disease
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    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    Avoidance and escape conditioning adjust adult neurogenesis to conserve a fit hippocampus in adult male rodents
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    Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis
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    Two parabrachial Cck neurons involved in the feedback control of thirst or salt appetite
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    The potential use of ascorbic acid to recover the cellular senescence of lipopolysaccharide-induced human apical papilla cells: an in vitro study
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    Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity
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    ADSC-Exos outperform BMSC-Exos in alleviating hydrostatic pressure-induced injury to retinal ganglion cells by upregulating nerve growth factors
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    Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence
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    Gbb glutathionylation promotes its proteasome-mediated degradation to inhibit synapse growth
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    Microenvironment-induced CREPT expression by cancer-derived small extracellular vesicles primes field cancerization
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    Rebalancing TGF-β/PGE2 breaks RT-induced immunosuppressive barriers by enhancing tumor-infiltrated dendritic cell homing
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    Cortical somatostatin interneuron subtypes form cell-type-specific circuits
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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  156. Dec 2023
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    Myeloma extracellular vesicle-derived RAGE increases inflammatory responses and myotube atrophy in multiple myeloma through activation of the TLR4/NF-κB p65 pathway
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  158. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sensory neurons couple arousal and foraging decisions in Caenorhabditis elegans
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    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
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    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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    Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates
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    Antenatal Dexamethasone Treatment Induces Sex-dependent Upregulation of NTPDase1/CD39 and Ecto-5ʹ-nucleotidase/CD73 in the Rat Fetal Brain
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    Reducing the prosthesis modulus by inclusion of an open space lattice improves osteogenic response in a sheep model of extraarticular defect
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    From biosynthesis and beyond—Loss or overexpression of the cytokinin synthesis gene, iptA, alters cytokinesis and mitochondrial and amino acid metabolism in Dictyostelium discoideum
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    Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
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    RAF-like protein kinases mediate a deeply conserved, rapid auxin response
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    Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells
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    Golgi-to-ER retrograde transport prevents premature differentiation of Drosophila type II neuroblasts via Notch-signal-sending daughter cells
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    Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells
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    Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration
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    Cerebellar contribution to autism-relevant behaviors in fragile X syndrome models
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    An outer membrane determinant for RNA phage genome entry in Pseudomonas aeruginosa
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    Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk
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    Sex and interspecies differences in ESR2-expressing cell distributions in mouse and rat brains
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    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
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    A cluster of neuropeptide S neurons regulates breathing and arousal
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    A tridimensional atlas of the developing human head
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