4,620 Matching Annotations
  1. Aug 2024
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    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    sciencedirect.com/science/article/pii/S2211124724009720
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    Spinal motor neuron development and metabolism are transcriptionally regulated by Nuclear Factor IA
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    biorxiv.org/content/10.1101/2024.06.26.600888v1
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    Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells
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    sciencedirect.com/science/article/pii/S1097276524006191
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    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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    sciencedirect.com/science/article/pii/S109727652400618X
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    Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S2666379124003835
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    Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy
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    sciencedirect.com/science/article/pii/S2211124724009690
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    Prior Fc receptor activation primes macrophages for increased sensitivity to IgG via long-term and short-term mechanisms
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    sciencedirect.com/science/article/pii/S153458072400457X
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    Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2211124724009203
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    Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation
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    sciencedirect.com/science/article/pii/S1097276524005896
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    Protocol for the application of single-cell damage in murine intestinal organoid models
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    Protocol for machine-learning-based 3D image analysis of nuclear envelope tubules in cultured cells
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    The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
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    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
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    Purinosomes spatially co-localize with mitochondrial transporters
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    Redox heterogeneity in mouse embryonic stem cells individualizes cell fate decisions
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    cGAS-activated endothelial cell–T cell cross-talk initiates tertiary lymphoid structure formation
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    Cryo-EM structure of monomeric CXCL12-bound CXCR4 in the active state
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    Do extracellular vesicles have specific target cells?; Extracellular vesicle mediated embryo maternal communication
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    Structural insights into ligand recognition and activation of the succinate receptor SUCNR1
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    The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
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    Regulation of the DLC3 tumor suppressor by a novel phosphoswitch
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    Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma
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    Basis of gene-specific transcription regulation by the Integrator complex
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    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle
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    SigmaR1 shapes rough endoplasmic reticulum membrane sheets
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    cell.com/developmental-cell/fulltext/S1534-5807(24)00382-4
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    Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard
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    Highly specific σ<sub>2</sub>R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response
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    Glycosylated Delta-RBD mucosal vaccine elicits broadly neutralizing antibodies with protection against SARS-CoV-2 challenge
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    USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis
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    Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening
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    pubs.acs.org/doi/10.1021/acs.jmedchem.2c00864
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    Posttranslational modification of microtubules by the MATCAP detyrosinase
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    science.org/doi/10.1126/science.abn6020
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    SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
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    Differences in Cell-Intrinsic Inflammatory Programs of Yolk Sac and Bone Marrow Macrophages
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    Characterization of Type 1 Angiotensin II Receptor Activation Induced Dual-Specificity MAPK Phosphatase Gene Expression Changes in Rat Vascular Smooth Muscle Cells
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    HTLV-2 Encoded Antisense Protein APH-2 Suppresses HIV-1 Replication
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    A method for benchmarking genetic screens reveals a predominant mitochondrial bias
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    C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation
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    Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation
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    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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    ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression
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    Activation of Multiple G Protein Pathways to Characterize the Five Dopamine Receptor Subtypes Using Bioluminescence Technology
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    pubs.acs.org/doi/full/10.1021/acsptsci.3c00339
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    Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex
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    science.org/doi/abs/10.1126/sciadv.abh2974
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    The membrane transporter SLC25A48 enables transport of choline into human mitochondria.
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    Protocol for the isolation and proteomic analysis of pathological tau-seeds
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    Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors
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    Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor
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    The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
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    Decoding RNA Metabolism by RNA-linked CRISPR Screening in Human Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11291135/
  51. Jul 2024
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    Inflammatory gene regulation by Cdc42 in airway epithelial cells
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    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
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    Clofazimine inhibits innate immunity against Mycobacterium tuberculosis by NF-κB
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    journals.asm.org/doi/10.1128/msphere.00254-24
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    Identification and structural characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3
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    onlinelibrary.wiley.com/doi/10.1002/eji.202451079
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    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
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    Presynaptic Rac1 in the hippocampus selectively regulates working memory
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    DNA damage-mediated FTO downregulation promotes CRPC progression by inhibiting FOXO3a via an m6A-dependent mechanism
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    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
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    Synaptotagmin-11 facilitates assembly of a presynaptic signaling complex in post-Golgi cargo vesicles
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    Protocol for linking enhanced interferon immunity to virus resistance in gene-knockout zebrafish
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    ncbi.nlm.nih.gov/pmc/articles/PMC11260832/
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    Assembly mechanism of Integrator’s RNA cleavage module
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    Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
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    The human mitochondrial translation factor TACO1 alleviates mitoribosome stalling at polyproline stretches
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    2′-O-methylation at internal sites on mRNA promotes mRNA stability
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    Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity
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    Efficient, specific, and combinatorial control of endogenous exon splicing with dCasRx-RBM25
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    Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
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    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
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    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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    Enhancer demethylation-regulated gene score identified molecular subtypes, inspiring immunotherapy or CDK4/6 inhibitor therapy in oesophageal squamous cell carcinoma
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    The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells
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    Construction of mirror-image RNA nanostructure for enhanced biostability and drug delivery efficiency
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    biorxiv.org/content/10.1101/2024.07.17.603907v1
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    AXIN2 promotes degradation of AXIN1 through tankyrase in colorectal cancer cells
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    Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
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    BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion
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    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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    High-throughput screening for cell binding and repulsion peptides on multifunctionalized surfaces
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    Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms
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    Atg8/LC3 controls systemic nutrient surplus signaling in flies and humans
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    Humoral and cellular immune responses following Omicron BA.2.2 breakthrough infection and Omicron BA.5 reinfection
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    Characterising replisome disassembly in human cells
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    DiPRO1 distinctly reprograms muscle and mesenchymal cancer cells
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    CRISPR Base Editing to Create Potential Charcot–Marie–Tooth Disease Models with High Editing Efficiency: Human Induced Pluripotent Stem Cell Harboring SH3TC2 Variants
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    Evolution of protective SARS-CoV-2-specific B and T cell responses upon vaccination and Omicron breakthrough infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC11225850/
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    Discovery of a novel hybrid coumarin-hydroxamate conjugate targeting the HDAC1-Sp1-FOSL2 signaling axis for breast cancer therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11247895/
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    Molecular mechanism of contactin 2 homophilic interaction
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    Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus
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    Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
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  91. www.cell.com www.cell.com
    Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1
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