1,833 Matching Annotations
  1. Sep 2020
  2. www.nature.com www.nature.com
    Spt6 is a maintenance factor for centromeric CENP-A
    1
    1. scibot 03 Sep 2020
      mAB α Flag

      DOI: 10.1038/s41467-020-16695-7

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    nature.com/articles/s41467-020-16695-7
  3. elifesciences.org elifesciences.org
    A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay
    1
    1. scibot 03 Sep 2020
      Anti-FLAG M2 mouse monoclonal

      DOI: 10.7554/eLife.54995

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    elifesciences.org/articles/54995
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oncogenic properties and signaling basis of the PAX8‐GLIS3 fusion gene
    1
    1. scibot 03 Sep 2020
      FLAG M2

      DOI: 10.1002/ijc.33040

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33040
  5. journals.plos.org journals.plos.org
    HIV protease cleaves the antiviral m6A reader protein YTHDF3 in the viral particle
    1
    1. scibot 03 Sep 2020
      RRID:AB_262044

      DOI: 10.1371/journal.ppat.1008305

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    journals.plos.org/plospathogens/article
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target
    1
    1. scibot 03 Sep 2020
      RRID:AB_262044

      DOI: 10.1038/s41419-020-2463-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC7181796/
  7. www.cell.com www.cell.com
    Gene-Specific Control of tRNA Expression by RNA Polymerase II
    1
    1. scibot 03 Sep 2020
      RRID:AB_262044

      DOI: 10.1016/j.molcel.2020.03.023

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30191-X
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MicroRNA miR-7 regulates secretion of insulin-like peptides
    1
    1. scibot 03 Sep 2020
      RRID:AB_262044

      DOI: 10.1210/endocr/bqz040

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    ncbi.nlm.nih.gov/pmc/articles/PMC7029775/
  9. Aug 2020
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The integrated stress response induces R-loops and hinders replication fork progression
    1
    1. scibot 27 Aug 2020
      RRID:AB_262044

      DOI: 10.1038/s41419-020-2727-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC7366693/
  11. academic.oup.com academic.oup.com
    Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
    1
    1. scibot 20 Aug 2020
      anti-FLAG M2

      DOI: 10.1093/hmg/ddaa077

      Resource: (Sigma-Aldrich Cat# F1804, RRID:AB_262044)

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    academic.oup.com/hmg/article/29/9/1547/5825277
  12. Jan 2020
  13. www.sciencedirect.com www.sciencedirect.com
    In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.celrep.2019.08.026

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    sciencedirect.com/science/article/pii/S2211124719310605
  14. www.sciencedirect.com www.sciencedirect.com
    A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.stem.2019.06.008

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    sciencedirect.com/science/article/pii/S1934590919302723
  15. www.sciencedirect.com www.sciencedirect.com
    A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.celrep.2019.08.047

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    sciencedirect.com/science/article/pii/S2211124719310952
  16. www.sciencedirect.com www.sciencedirect.com
    A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.cell.2019.10.032

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    sciencedirect.com/science/article/pii/S0092867419311821
  17. www.sciencedirect.com www.sciencedirect.com
    The Spatiotemporal Construction of the Axon Initial Segment via KIF3/KAP3/TRIM46 Transport under MARK2 Signaling
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.celrep.2019.07.093

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    sciencedirect.com/science/article/pii/S2211124719310095
  18. www.sciencedirect.com www.sciencedirect.com
    Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.celrep.2019.09.033

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    sciencedirect.com/science/article/pii/S2211124719312215
  19. www.sciencedirect.com www.sciencedirect.com
    Oncogenic Biogenesis of pri-miR-17∼92 Reveals Hierarchy and Competition among Polycistronic MicroRNAs
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.molcel.2019.05.033

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    sciencedirect.com/science/article/pii/S1097276519304058
  20. www.sciencedirect.com www.sciencedirect.com
    A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.molcel.2019.06.010

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    sciencedirect.com/science/article/pii/S1097276519304435
  21. www.sciencedirect.com www.sciencedirect.com
    DLK mediates the neuronal intrinsic immune response and regulates glial reaction and neuropathic pain
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.expneurol.2019.113056

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    sciencedirect.com/science/article/pii/S0014488619302055
  22. www.sciencedirect.com www.sciencedirect.com
    An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.molcel.2019.05.020

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    sciencedirect.com/science/article/pii/S1097276519303922
  23. www.sciencedirect.com www.sciencedirect.com
    Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.cell.2019.11.016

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    sciencedirect.com/science/article/pii/S0092867419312723
  24. www.sciencedirect.com www.sciencedirect.com
    The selector genes midline and H15 control ventral leg pattern by both inhibiting Dpp signaling and specifying ventral fate
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.ydbio.2019.05.012

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    sciencedirect.com/science/article/pii/S0012160618306079
  25. www.sciencedirect.com www.sciencedirect.com
    Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.chom.2019.08.017

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    sciencedirect.com/science/article/pii/S1931312819304263
  26. www.sciencedirect.com www.sciencedirect.com
    Sleep Regulation by Neurotensinergic Neurons in a Thalamo-Amygdala Circuit
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.neuron.2019.05.015

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    sciencedirect.com/science/article/pii/S0896627319304404
  27. www.sciencedirect.com www.sciencedirect.com
    RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.molcel.2019.07.029

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    sciencedirect.com/science/article/pii/S1097276519305842
  28. www.sciencedirect.com www.sciencedirect.com
    RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.celrep.2019.09.026

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    sciencedirect.com/science/article/pii/S2211124719312033
  29. www.sciencedirect.com www.sciencedirect.com
    Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.chom.2019.09.012

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    sciencedirect.com/science/article/pii/S1931312819304792
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    Translational Regulation of Non-autonomous Mitochondrial Stress Response Promotes Longevity
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.celrep.2019.06.078

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    sciencedirect.com/science/article/pii/S2211124719308587
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    Usp9X Controls Ankyrin-Repeat Domain Protein Homeostasis during Dendritic Spine Development
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.neuron.2019.11.003

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    sciencedirect.com/science/article/pii/S0896627319309663
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    Family-wide Annotation of Enzymatic Pathways by Parallel In Vivo Metabolomics
    1
    1. scibot 13 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.chembiol.2019.09.009

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    sciencedirect.com/science/article/pii/S2451945619303149
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs
    1
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      RRID:AB_262044

      DOI: 10.7554/eLife.44635

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    ncbi.nlm.nih.gov/pmc/articles/PMC6570481/
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    Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters
    1
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      DOI: 10.1016/j.molcel.2019.06.011

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    sciencedirect.com/science/article/pii/S1097276519304447
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    VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells
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      DOI: 10.1016/j.cell.2019.05.051

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    sciencedirect.com/science/article/pii/S0092867419306221
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    Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
    1
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      DOI: 10.1016/j.stem.2019.05.013

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    sciencedirect.com/science/article/pii/S1934590919302176
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    Sister DNA Entrapment between Juxtaposed Smc Heads and Kleisin of the Cohesin Complex
    1
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      DOI: 10.1016/j.molcel.2019.05.023

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    sciencedirect.com/science/article/pii/S1097276519303958
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    A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis
    1
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      DOI: 10.1016/j.celrep.2019.11.018

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    sciencedirect.com/science/article/pii/S2211124719314895
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 1 family proteins promote Slimb-dependent Expanded degradation
    1
    1. scibot 13 Jan 2020
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      DOI: 10.7554/eLife.46592

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    ncbi.nlm.nih.gov/pmc/articles/PMC6768662/
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    PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia
    1
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      DOI: 10.1016/j.molcel.2019.09.018

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    sciencedirect.com/science/article/pii/S1097276519307233
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    DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation
    1
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      DOI: 10.1016/j.celrep.2019.12.021

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    sciencedirect.com/science/article/pii/S2211124719316717
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    PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression
    1
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    GCNA Preserves Genome Integrity and Fertility Across Species
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    RHON1 Co-transcriptionally Resolves R-Loops for Arabidopsis Chloroplast Genome Maintenance
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    Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation
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    The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore
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    CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity
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    AAGAB Controls AP2 Adaptor Assembly in Clathrin-Mediated Endocytosis
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    Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning
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    P Granules Protect RNA Interference Genes from Silencing by piRNAs
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    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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    C9-ALS/FTD-linked proline–arginine dipeptide repeat protein associates with paraspeckle components and increases paraspeckle formation
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    henn-1/HEN1 Promotes Germline Immortality in Caenorhabditis elegans
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    Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
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    The SUMO Isopeptidase SENP6 Functions as a Rheostat of Chromatin Residency in Genome Maintenance and Chromosome Dynamics
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    Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells
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    The N-Degron Pathway Mediates ER-phagy
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    VCP Machinery Mediates Autophagic Degradation of Empty Argonaute
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    CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation
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    RNA-RNA Interactomes of ProQ and Hfq Reveal Overlapping and Competing Roles
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    Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel
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    Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
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    Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons
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    Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specific cerebellar synapses and motor functions
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    Naa10p Inhibits Beige Adipocyte-Mediated Thermogenesis through N-α-acetylation of Pgc1α
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    Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1
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    Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover
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    Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor
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    Vezatin is required for the maturation of the neuromuscular synapse
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    Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1
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    UTS2B defines a novel enteroendocrine cell population and regulates GLP-1 secretion through SSTR5 in male mice
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    Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus
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    USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification
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    GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile
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    Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice
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    Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors
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    PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin
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    Expression of the double‐stranded RNA‐dependent kinase PKR influences osteosarcoma attachment independent growth, migration, and invasion
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    Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer
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    Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation
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    Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis
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    The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability
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    RPA Phosphorylation Inhibits DNA Resection
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    Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance
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    Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome
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    A bivalent antihypertensive vaccine targeting L‐type calcium channel and angiotensin II type 1 receptor
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    Chromatin Remodeling in Response to BRCA2-Crisis
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    Syndecan-1 Mediates Sorting of Soluble Lipoprotein Lipase with Sphingomyelin-Rich Membrane in the Golgi Apparatus
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    Species specific differences in use of ANP32 proteins by influenza A virus
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    LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis
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    Epigenetic silencing of a multifunctional plant stress regulator
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    Structure of the Cardiac Sodium Channel
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    Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly
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    Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107
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    SALM1 controls synapse development by promoting F‐actin/PIP2‐dependent Neurexin clustering
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    The Toll Signaling Pathway Targets the Insulin-like Peptide Dilp6 to Inhibit Growth in Drosophila
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    FOXO1 negates the cooperative action of FOXL2 C134W and SMAD3 in CYP19 expression in HGrC1 cells by sequestering SMAD3
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    CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation
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    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
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    Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase
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    SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism
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    Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity
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    The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1
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    The Gene-Silencing Protein MORC-1 Topologically Entraps DNA and Forms Multimeric Assemblies to Cause DNA Compaction
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    The Tricellular Junction Protein Sidekick Regulates Vertex Dynamics to Promote Bicellular Junction Extension
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    Unique Structural Features of the Mitochondrial AAA+ Protease AFG3L2 Reveal the Molecular Basis for Activity in Health and Disease
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    53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination
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    In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation
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    Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1−Akt signaling pathway
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    DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members
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      DOI: 10.1073/pnas.1809430115

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    SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation
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    Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
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    Mg2+-ATP Sensing in CNNM, a Putative Magnesium Transporter
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    The Translational Landscape of the Human Heart
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    OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin
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    Dynamics of Notch-Dependent Transcriptional Bursting in Its Native Context
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    Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies
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    Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers
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    Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector
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    Role of Nampt-Sirt6 Axis in Renal Proximal Tubules in Extracellular Matrix Deposition in Diabetic Nephropathy
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    Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site
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    TOP2β-Dependent Nuclear DNA Damage Shapes Extracellular Growth Factor Responses via Dynamic AKT Phosphorylation to Control Virus Latency
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    sciencedirect.com/science/article/pii/S2211124719305017
  202. elifesciences.org elifesciences.org
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    1. scibot 12 Jan 2020
      RRID:AB_262044

      DOI: 10.7554/eLife.40396

      Resource: (Sigma-Aldrich Cat# F1804, RRID:AB_262044)

      Curator: @Naa003

      SciCrunch record: RRID:AB_262044

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      RRID:AB_262044 RRIDCUR:Validated
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  203. www.sciencedirect.com www.sciencedirect.com
    METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation
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    1. scibot 12 Jan 2020
      RRID:AB_262044

      DOI: 10.1016/j.molcel.2019.03.040

      Resource: (Sigma-Aldrich Cat# F1804, RRID:AB_262044)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_262044

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      RRID:AB_262044 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519302692