4,894 Matching Annotations
  1. Sep 2024
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    Neoself-antigens are the primary target for autoreactive T cells in human lupus
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    sciencedirect.com/science/article/pii/S0092867424009139
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    Protocol to identify receptors of secreted proteins through CRISPR-Cas9 whole-genome screening technology
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    sciencedirect.com/science/article/pii/S2666166724004805
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    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
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    Validation of a PD-1/CD28 chimeric switch receptor to augment CAR-T function in dogs with spontaneous B cell lymphoma
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    sciencedirect.com/science/article/pii/S2589004224020881
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    Sorafenib and SIAIS361034, a novel PROTAC degrader of BCL-xL, display synergistic antitumor effects on hepatocellular carcinoma with minimal hepatotoxicity
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    sciencedirect.com/science/article/pii/S0006295224005422
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    A guide to selecting high-performing antibodies for Huntingtin (UniProt ID: P42858) for use in western blot, immunoprecipitation, and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC11384196/
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    MG53 suppresses tumor growth via transcriptional inhibition of KIF11 in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1936523324002456
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    Distinct tumor architectures and microenvironments for the initiation of breast cancer metastasis in the brain
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    sciencedirect.com/science/article/pii/S1535610824003143
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    RAPIDASH: Tag-free enrichment of ribosome-associated proteins reveals composition dynamics in embryonic tissue, cancer cells, and macrophages
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    sciencedirect.com/science/article/pii/S1097276524007007
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.15010
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    A nature-inspired HIF stabilizer derived from a highland-adaptation insertion of plateau pika Epas1 protein
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    sciencedirect.com/science/article/pii/S2211124724010787
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17264
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    Clofazimine inhibits innate immunity against Mycobacterium tuberculosis by NF-κB
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    ncbi.nlm.nih.gov/pmc/articles/PMC11351037/
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    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
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    sciencedirect.com/science/article/pii/S0092867424009115
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    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
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    New dual inducible cellular model to investigate temporal control of oncogenic cooperating genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11377716/
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    Circular RNA HMGCS1 sponges MIR4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11377038/
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    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
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    Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia
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    Intestinal newborn regulatory B cell antibodies modulate microbiota communities
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    sciencedirect.com/science/article/pii/S1931312824003172
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    TGF-β and RAS jointly unmask primed enhancers to drive metastasis
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    Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity
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    CD34 distribution in C-fiber low threshold mechanoreceptors in the mouse dorsal root ganglion and spinal cord
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    sciencedirect.com/science/article/pii/S0006899324004815
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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    Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD
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    A compact, versatile drug-induced splicing switch system with minimal background expression
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    Inseparable/IER3IP1 are essential for cytokinesis in Drosophila neuroblast and human cells
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    biorxiv.org/content/10.1101/2024.07.20.604396v2
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    Inhibitory co-receptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming
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    PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369622/
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    Pharmacological chaperones restore proteostasis of epilepsy-associated GABAA receptor variants
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    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    Decoupling HIV-1 antiretroviral drug inhibition from plasma antibody activity to evaluate broadly neutralizing antibody therapeutics and vaccines
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    sciencedirect.com/science/article/pii/S2666379124004233
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    The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis
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    E3 ubiquitin ligase ANKIB1 attenuates antiviral immune responses by promoting K48-linked polyubiquitination of MAVS
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    sciencedirect.com/science/article/pii/S2211124724010386
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    PLXNA1 confers enzalutamide resistance in prostate cancer via AKT signaling pathway
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    sciencedirect.com/science/article/pii/S1476558624000897
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    GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
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    sciencedirect.com/science/article/pii/S1535610824003052
  38. Aug 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutathione-S-Transferase Theta 2 (GSTT2) Modulates the Response to Bacillus Calmette–Guérin Immunotherapy in Bladder Cancer Patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC11354831/
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    Protocol for the in vitro reconstruction of site-specifically phosphorylated RNA Pol II to identify the recruitment of novel transcription regulators
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    Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats
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    MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11348129/
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    Conservation of antiviral systems across domains of life reveals immune genes in humans
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    sciencedirect.com/science/article/pii/S1931312824002890
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    PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
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    Normalization of Snai1-mediated vessel dysfunction increases drug response in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347376/
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    Cordycepin exhibits both antiviral and anti-inflammatory effects against dengue virus infection
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    Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10641717/
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    Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals
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    Therapeutic siRNA targeting PLIN2 ameliorates steatosis, inflammation, and fibrosis in steatotic liver disease models
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    sciencedirect.com/science/article/pii/S0022227524001408
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    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
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    Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function
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    sciencedirect.com/science/article/pii/S2451945624003192
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    CRISPR-Cas9 screening develops an epigenetic and transcriptional gene signature for risk stratification and target prediction in neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11338898/
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    Cadmium activation of wild-type and constitutively active estrogen receptor alpha
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341946/
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    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses
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    nature.com/articles/s41593-024-01720-5
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    RNA interacts with topoisomerase I to adjust DNA topology
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    Artificially inserted strong promoter containing multiple G-quadruplexes induces long-range chromatin modification
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    Acetate enables metabolic fitness and cognitive performance during sleep disruption
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    DiPRO1 distinctly reprograms muscle and mesenchymal cancer cells
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    Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
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    A genetic basis for sex differences in Xp11 translocation renal cell carcinoma
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    Tentonin 3 is a pore-forming subunit of a slow inactivation mechanosensitive channel
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    BDNF-dependent nano-organization of Neogenin and the WAVE Regulatory Complex promotes actin remodelling in dendritic spines
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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    Vaccine priming of rare HIV broadly neutralizing antibody precursors in non-human primates
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    pmc.ncbi.nlm.nih.gov/articles/PMC11309785/
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    Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer
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    biorxiv.org/content/10.1101/2024.07.10.602941v2
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    Functional characterization of the SDR42E1 reveals its role in vitamin D biosynthesis
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    The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response
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    The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress
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    Multiple mechanisms contribute to acquired TRAIL resistance in multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11299348/
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    A High-Throughput Screening Identifies MCM Chromatin loading Inhibitors Targeting Cells with increased Replication Origins
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    A broad-spectrum multiepitope vaccine against seasonal influenza A and B viruses in mice
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    ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment
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    sciencedirect.com/science/article/pii/S2090123224003060
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    The FXR1 network acts as a signaling scaffold for actomyosin remodeling
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    Anticancer potential of NSAID-derived tris(pyrazolyl)methane ligands in iron( ii ) sandwich complexes
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    pubs.rsc.org/en/content/articlehtml/2024/dt/d4dt00920g
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    SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
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    cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
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    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    Spinal motor neuron development and metabolism are transcriptionally regulated by Nuclear Factor IA
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    biorxiv.org/content/10.1101/2024.06.26.600888v1
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    Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells
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    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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    Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer’s disease
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    Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy
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    Prior Fc receptor activation primes macrophages for increased sensitivity to IgG via long-term and short-term mechanisms
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    Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity
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    Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation
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    Protocol for the application of single-cell damage in murine intestinal organoid models
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    Protocol for machine-learning-based 3D image analysis of nuclear envelope tubules in cultured cells
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    The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
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    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
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    nature.com/articles/s41594-024-01338-y
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    Purinosomes spatially co-localize with mitochondrial transporters
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    Redox heterogeneity in mouse embryonic stem cells individualizes cell fate decisions
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