299 Matching Annotations
  1. Jul 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury
    1
    1. scibot 31 Jul 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2018.12.022

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    sciencedirect.com/science/article/pii/S0092867418316362
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.immuni.2018.10.007

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    ncbi.nlm.nih.gov/pmc/articles/PMC6303219/
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    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.cell.2018.10.038

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    sciencedirect.com/science/article/pii/S0092867418313941
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    Untitled document
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    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.immuni.2018.09.024

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    sciencedirect.com/science/article/pii/S1074761318304394
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    Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation
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    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.chom.2017.06.006

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    sciencedirect.com/science/article/pii/S1931312817302469
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    Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity
    2
    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.cell.2017.05.005

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    2. scibot 28 Jul 2021
      AB_1107769

      DOI: 10.1016/j.cell.2017.05.005

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    sciencedirect.com/science/article/pii/S0092867417305329
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma
    1
    1. scibot 21 Jul 2021
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      DOI: 10.1016/j.isci.2021.102759

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    ncbi.nlm.nih.gov/pmc/articles/PMC8267546/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipopolysaccharide-mediated chronic inflammation promotes tobacco carcinogen-induced lung cancer and determines the efficacy of immunotherapy
    1
    1. scibot 03 Jul 2021
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      DOI: 10.1158/0008-5472.CAN-20-1994

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    ncbi.nlm.nih.gov/pmc/articles/PMC7878420/
  10. Jun 2021
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    Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
    1
    1. scibot 23 Jun 2021
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2021.109285

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    sciencedirect.com/science/article/pii/S2211124721006562
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    A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
    1
    1. scibot 19 Jun 2021
      RRID:_AB_1107769

      DOI: 10.1016/j.immuni.2021.05.016

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    sciencedirect.com/science/article/pii/S1074761321002223
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    Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response
    1
    1. scibot 15 Jun 2021
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      DOI: 10.1016/j.xpro.2021.100595

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    sciencedirect.com/science/article/pii/S2666166721003026
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    GPR34-mediated sensing of lysophosphatidylserine released by apoptotic neutrophils activates type 3 innate lymphoid cells to mediate tissue repair
    1
    1. scibot 09 Jun 2021
      RRID:AB_1107769

      DOI: 10.1016/j.immuni.2021.05.007

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    sciencedirect.com/science/article/pii/S1074761321002132
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection
    1
    1. scibot 04 Jun 2021
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      DOI: 10.7554/eLife.65762

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    ncbi.nlm.nih.gov/pmc/articles/PMC8163503/
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    Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
    1
    1. scibot 03 Jun 2021
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      DOI: 10.1016/j.cell.2021.05.021

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    sciencedirect.com/science/article/pii/S0092867421006516
  17. May 2021
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    The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
    1
    1. scibot 12 May 2021
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      DOI: 10.1016/j.immuni.2021.04.019

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    sciencedirect.com/science/article/pii/S1074761321001813
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    A vaccine inducing solely cytotoxic T lymphocytes fully prevents Zika virus infection and fetal damage
    1
    1. scibot 12 May 2021
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      DOI: 10.1016/j.celrep.2021.109107

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    sciencedirect.com/science/article/pii/S2211124721004411
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    BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse
    1
    1. scibot 09 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.stem.2020.06.022

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    sciencedirect.com/science/article/pii/S1934590920302897
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    Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress
    1
    1. scibot 08 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.molcel.2021.02.038

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    sciencedirect.com/science/article/pii/S1097276521001684
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    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
    1
    1. scibot 08 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.molcel.2021.01.010

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    sciencedirect.com/science/article/pii/S1097276521000101
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    Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium
    1
    1. scibot 07 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.immuni.2020.12.004

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    sciencedirect.com/science/article/pii/S107476132030532X
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    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
    1
    1. scibot 07 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.immuni.2020.09.006

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    sciencedirect.com/science/article/pii/S1074761320304003
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
    1
    1. scibot 05 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2021.109071

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    ncbi.nlm.nih.gov/labs/pmc/articles/PMC8148423/
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    Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation
    1
    1. scibot 01 May 2021
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      DOI: 10.1016/j.immuni.2021.04.007

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    sciencedirect.com/science/article/pii/S1074761321001692
  27. Apr 2021
  28. www.sciencedirect.com www.sciencedirect.com
    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
    1
    1. scibot 30 Apr 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cmet.2020.10.021

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    sciencedirect.com/science/article/pii/S1550413120305544
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    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
    1
    1. scibot 29 Apr 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cmet.2020.10.012

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    sciencedirect.com/science/article/pii/S1550413120305453
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    CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
    1
    1. scibot 26 Apr 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cmet.2021.02.015

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    sciencedirect.com/science/article/pii/S1550413121000711
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    Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis
    1
    1. scibot 24 Apr 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2020.08.020

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    sciencedirect.com/science/article/pii/S0092867420310114
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    The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis
    1
    1. scibot 24 Apr 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2020.06.029

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    sciencedirect.com/science/article/pii/S0092867420308060
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    Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance
    1
    1. scibot 22 Apr 2021
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      DOI: 10.1016/j.ccell.2020.12.023

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    sciencedirect.com/science/article/pii/S1535610820306711
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    The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes
    1
    1. scibot 22 Apr 2021
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      DOI: 10.1016/j.ccell.2020.09.001

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    sciencedirect.com/science/article/pii/S1535610820304323
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    Interaction between Staphylococcus Agr virulence and neutrophils regulates pathogen expansion in the skin
    1
    1. scibot 14 Apr 2021
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      DOI: 10.1016/j.chom.2021.03.007

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    sciencedirect.com/science/article/pii/S1931312821001359
  36. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
    1
    1. scibot 06 Apr 2021
      InVivoPlus rat IgG2a isotype control

      DOI: 10.1016/j.immuni.2021.02.020

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    sciencedirect.com/science/article/pii/S1074761321000868
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    Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP
    1
    1. scibot 01 Apr 2021
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      DOI: 10.1016/j.celrep.2021.108919

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    sciencedirect.com/science/article/pii/S2211124721002333
  38. Mar 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection
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    1. scibot 29 Mar 2021
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      DOI: 10.1016/j.immuni.2021.01.003

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    sciencedirect.com/science/article/pii/S1074761321000261
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor
    1
    1. scibot 17 Mar 2021
      RRID:AB_1107769

      DOI: 10.1126/scisignal.aau4518

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    ncbi.nlm.nih.gov/pmc/articles/PMC7784968/
  41. www.sciencedirect.com www.sciencedirect.com
    Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
    1
    1. scibot 08 Mar 2021
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      DOI: 10.1016/j.ccell.2020.12.001

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    sciencedirect.com/science/article/pii/S1535610820306085
  42. Feb 2021
  43. www.jimmunol.org www.jimmunol.org
    Transcriptional Diversity and Niche-Specific Distribution of Leukocyte Populations during Staphylococcus aureus Craniotomy-Associated Biofilm Infection
    1
    1. scibot 28 Feb 2021
      RRID:AB_1107769

      DOI: 10.4049/jimmunol.2001042

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    jimmunol.org/content/206/4/751
  44. insight.jci.org insight.jci.org
    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
    1
    1. scibot 26 Feb 2021
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      DOI: 10.1172/jci.insight.134386

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    insight.jci.org/articles/view/134386
  45. elifesciences.org elifesciences.org
    IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus
    1
    1. scibot 25 Feb 2021
      RRID:AB_1107769

      DOI: 10.7554/eLife.45501

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    elifesciences.org/articles/45501
  46. www.cell.com www.cell.com
    Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation
    1
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      RRID:AB_1107769

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  47. Dec 2020
  48. www.sciencedirect.com www.sciencedirect.com
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
    1
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      BP0089

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  49. Oct 2020
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    PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
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    Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury
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  52. Sep 2020
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    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
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    TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes
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    Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis
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    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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    Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy
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    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
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    An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses
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    Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells
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    Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity
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    Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps
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    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
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    Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection
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      Isotype (rat IgG2a isotype)

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  67. Jan 2020
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors
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      DOI: 10.1016/j.cell.2019.05.047

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    T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation
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    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
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      DOI: 10.1016/j.cell.2019.08.032

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    B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer
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      DOI: 10.1016/j.cell.2019.10.028

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    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
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    Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis
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    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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    Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
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    Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
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    Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization
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    CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota
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    IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties
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    Staphylococcus aureus Leukocidins Target Endothelial DARC to Cause Lethality in Mice
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    Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis
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    Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury
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    Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
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  89. Nov 2018
  90. www-sciencedirect-com.ezproxy.is.ed.ac.uk www-sciencedirect-com.ezproxy.is.ed.ac.uk
    CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis
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    Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis
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    IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy
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    LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade
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    Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
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    Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity
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    RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis
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    Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
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    B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells
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    Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization
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    TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer
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    Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation
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    Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer
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  105. Nov 2017
  106. www.sciencedirect.com www.sciencedirect.com
    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
    1
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    Dietary Manganese Promotes Staphylococcal Infection of the Heart
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    Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever
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    Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
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    sciencedirect.com/science/article/pii/S1074761317302339