776 Matching Annotations
  1. Apr 2023
  2. www.sciencedirect.com www.sciencedirect.com
    ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion
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    1. scibot 13 Apr 2023
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    sciencedirect.com/science/article/pii/S1534580723001302
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    Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila
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    sciencedirect.com/science/article/pii/S1534580723001041
  4. 52.53.155.43 52.53.155.43
    Evolution of promoter-proximal pausing enabled a new layer of transcription control
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    1. scibot 11 Apr 2023
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      DOI: 10.1101/2023.02.19.529146

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    52.53.155.43/3c5d712daefd9b4515c968980af0bacbaf86aeb6/2023.02.19.529146v1.full-html.html
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    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
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    sciencedirect.com/science/article/pii/S2211124723003510
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    CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth
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    sciencedirect.com/science/article/pii/S2211124723003273
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    Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila
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    1. scibot 05 Apr 2023
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      DOI: 10.1101/2023.02.11.528119

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    biorxiv.org/content/10.1101/2023.02.11.528119v4
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10060683/
  9. Mar 2023
  10. 52.53.155.43 52.53.155.43
    v1_covered (2)-html.html
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  11. 52.53.155.43 52.53.155.43
    Behavioral circatidal rhythms require Bmal1 in Parhyale hawaiensis
    2
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    2. scibot 28 Mar 2023
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    52.53.155.43/55f587df65f1160749e1a55ae3e22c625b645f66/PIIS0960982223003032-html.html
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    Ascending neurons convey behavioral state to integrative sensory and action selection brain regions
    1
    1. scibot 29 Mar 2023
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  13. europepmc.org europepmc.org
    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
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    1. scibot 28 Mar 2023
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    europepmc.org/article/med/36952341
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    Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell
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    sciencedirect.com/science/article/pii/S1931312823001051
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    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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    sciencedirect.com/science/article/pii/S2211124723003200
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A searchable image resource of Drosophila GAL4 driver expression patterns with single neuron resolution
    1
    1. scibot 23 Mar 2023
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      DOI: 10.7554/eLife.80660

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    ncbi.nlm.nih.gov/pmc/articles/PMC10030108/
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    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
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    1. scibot 22 Mar 2023
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    sciencedirect.com/science/article/pii/S0021925823002636
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    The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells
    2
    1. scibot 16 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112245

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    sciencedirect.com/science/article/pii/S2211124723002565
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer
    1
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      DOI: 10.1158/1078-0432.CCR-21-3603

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    ncbi.nlm.nih.gov/pmc/articles/PMC9481728/
  20. www.nature.com www.nature.com
    Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation
    1
    1. scibot 14 Mar 2023
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      DOI: 10.1038/s41586-023-05802-5

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    Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells
    1
    1. scibot 11 Mar 2023
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      DOI: 10.1016/j.chembiol.2023.02.006

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    sciencedirect.com/science/article/pii/S2451945623000557
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    Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1
    1
    1. scibot 11 Mar 2023
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      DOI: 10.1016/j.cmet.2023.02.004

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    sciencedirect.com/science/article/pii/S1550413123000402
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    FAM193A is a positive regulator of p53 activity
    1
    1. scibot 10 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112230

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    sciencedirect.com/science/article/pii/S2211124723002413
  24. www.cell.com www.cell.com
    TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1
    1
    1. scibot 10 Mar 2023
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      DOI: 10.1016/j.molcel.2023.02.023

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    cell.com/molecular-cell/abstract/S1097-2765(23)00150-8
  25. www.biorxiv.org www.biorxiv.org
    Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
    1
    1. scibot 08 Mar 2023
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      DOI: 10.1101/2023.01.11.523558

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    biorxiv.org/content/10.1101/2023.01.11.523558v1
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    Developmental mRNA clearance by PIWI-bound endo-siRNAs in Paramecium
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    sciencedirect.com/science/article/pii/S2211124723002243
  27. www.biorxiv.org www.biorxiv.org
    In vitro production of cat-restricted Toxoplasma pre-sexual stages by epigenetic reprogramming
    1
    1. scibot 03 Mar 2023
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      DOI: 10.1101/2023.01.16.524187

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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery
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      DOI: 10.7554/eLife.80640

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    ncbi.nlm.nih.gov/pmc/articles/PMC9946446/
  29. www.sciencedirect.com www.sciencedirect.com
    Sex peptide regulates female receptivity through serotoninergic neurons in Drosophila
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    1. scibot 01 Mar 2023
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      DOI: 10.1016/j.isci.2023.106123

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    sciencedirect.com/science/article/pii/S2589004223002006
  30. Feb 2023
  31. www.sciencedirect.com www.sciencedirect.com
    RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex
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      DOI: 10.1016/j.celrep.2023.112097

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    sciencedirect.com/science/article/pii/S2211124723001080
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    Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle
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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
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      DOI: 10.1158/2643-3230.BCD-21-0160

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    ncbi.nlm.nih.gov/pmc/articles/PMC9780084/
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    The clathrin adaptor complex-1 and Rab12 regulate post-Golgi trafficking of wild-type epidermal growth factor receptor (EGFR)
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  35. Jan 2023
  36. www.nature.com www.nature.com
    Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions
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      DOI: 10.1038/s41467-023-36042-w

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    nature.com/articles/s41467-023-36042-w
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    Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
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    sciencedirect.com/science/article/pii/S1097276522012175
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    Optimized protocols for chromatin immunoprecipitation of exogenously expressed epitope-tagged proteins
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    sciencedirect.com/science/article/pii/S2666166723000084
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    Identification of key microRNAs regulating ELOVL6 and glioblastoma tumorigenesis
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    sciencedirect.com/science/article/pii/S2667160323000078
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    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
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    sciencedirect.com/science/article/pii/S221112472300013X
  41. www.biorxiv.org www.biorxiv.org
    Intron retention of an adhesion GPCR generates single transmembrane-helix isoforms to enable 7TM-adhesion GPCR function
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    biorxiv.org/content/10.1101/2023.01.11.521585v1
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    SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
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    sciencedirect.com/science/article/pii/S2211124722018654
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    The NLRP1 and CARD8 inflammasomes detect reductive stress
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    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
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    Efficient and reversible Cas13d-mediated knockdown with an all-in-one lentivirus-vector
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    Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
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    The neutralization of B.1.617.1 and B.1.1.529 sera from convalescent patients and BBIBP-CorV vaccines
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    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
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    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
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    Tripartite Motif 38 Attenuates Cardiac Fibrosis after Myocardial Infarction by Suppressing TAK1 Activation via TAB2/3 Degradation
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    GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation
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    The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice
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    Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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  131. Jun 2022
  132. 52.53.155.43 52.53.155.43
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    An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma
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    Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1
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    Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis
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  141. May 2022
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain
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    Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
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    Walking strides direct rapid and flexible recruitment of visual circuits for course control in Drosophila
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    Targeted proteoform mapping uncovers specific Neurexin-3 variants required for dendritic inhibition
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A bidirectional switch in the Shank3 phosphorylation state biases synapses toward up- or downscaling
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  150. Apr 2022
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    Characterization and functional interrogation of the SARS-CoV-2 RNA interactome
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of a CRF1-Cre transgenic rat and the role of central amygdala CRF1 cells in nociception and anxiety-like behavior
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    Non-apoptotic activation of Drosophila caspase-2/9 modulates JNK signaling, the tumor microenvironment, and growth of wound-like tumors
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    Rapid and efficient degradation of endogenous proteins in vivo identifies stage-specific roles of RNA Pol II pausing in mammalian development
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    Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C
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    The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin-mediated receptor degradation contributes to development of tolerance to MrgC agonist-induced pain inhibition in neuropathic rats
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  159. Mar 2022
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    Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex
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    Mucus sialylation determines intestinal host-commensal homeostasis
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    Targeting HNRNPM inhibits cancer stemness and enhances antitumor immunity in Wnt-activated hepatocellular carcinoma
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    Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-dependent Manner
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    MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
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    Deficiency of Mesencephalic Astrocyte-derived Neurotrophic Factor Affects Neurogenesis in Mouse Brain
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    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
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    An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase
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    Recruitment of DNA to tumor-derived microvesicles
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  171. Feb 2022
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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    Imatinib and methazolamide ameliorate COVID-19-induced metabolic complications via elevating ACE2 enzymatic activity and inhibiting viral entry
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    DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding
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    Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes
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    PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II
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    CRAF dimerization with ARAF regulates KRAS-driven tumor growth
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    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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    scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
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    Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila
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    Harnessing rAAV-retro for gene manipulations in multiple pathways that are interrupted after spinal cord injury
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    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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    Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes
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    MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells
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    Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production
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    Coordinated repression of pro-differentiation genes via P-bodies and transcription maintains Drosophila intestinal stem cell identity
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    Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
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    LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity
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    RNF13 Dileucine Motif Variants L311S and L312P Interfere with Endosomal Localization and AP-3 Complex Association
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    RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development
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    A nonautophagic role of ATG5 in regulating cell growth by targeting c-Myc for proteasome-mediated degradation
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    A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function
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    MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal
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    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
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