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  1. Sep 2020
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ultrastructure of light-activated axons following optogenetic stimulation to produce late-phase long-term potentiation
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  3. www.nature.com www.nature.com
    Tead transcription factors differentially regulate cortical development
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    nature.com/articles/s41598-020-61490-5
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    Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations
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    FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex
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    Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
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    cell.com/cell-reports/abstract/S2211-1247(19)30406-1
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    Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
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    A new genetic strategy for targeting microglia in development and disease
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    The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis
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    A Conserved PDZ-Binding Motif in aPKC Interacts with Par-3 and Mediates Cortical Polarity
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    Inhibitory Interactions and Columnar Inputs to an Object Motion Detector in Drosophila
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    sciencedirect.com/science/article/pii/S2211124720300863
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    TMIE Defines Pore and Gating Properties of the Mechanotransduction Channel of Mammalian Cochlear Hair Cells
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    Controlling motor neurons of every muscle for fly proboscis reaching
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    A Multi-regional Network Encoding Heading and Steering Maneuvers in Drosophila
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      DOI: 10.1016/j.neuron.2020.01.009

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    Regulation of Nucleotide Metabolism and Germline Proliferation in Response to Nucleotide Imbalance and Genotoxic Stresses by EndoU Nuclease
    1
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      DOI: 10.1016/j.celrep.2020.01.050

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  16. www.cell.com www.cell.com
    A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
    1
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      DOI: 10.1016/j.cell.2020.02.017

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    cell.com/cell/fulltext/S0092-8674(20)30161-6
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    THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells
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      DOI: 10.1016/j.ccell.2019.12.014

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    Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss
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      DOI: 10.1016/j.molcel.2020.01.009

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    sciencedirect.com/science/article/pii/S1097276520300095
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    The Cation Channel TMEM63B Is an Osmosensor Required for Hearing
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      DOI: 10.1016/j.celrep.2020.107596

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    sciencedirect.com/science/article/pii/S2211124720305453
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    MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
    1
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      DOI: 10.1016/j.celrep.2020.107860

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  21. academic.oup.com academic.oup.com
    Cellular Heterogeneity of the Luteinizing Hormone Receptor and Its Significance for Cyclic GMP Signaling in Mouse Preovulatory Follicles
    1
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      DOI: 10.1210/endocr/bqaa074

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    Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
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      DOI: 10.1016/j.molcel.2020.01.008

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    sciencedirect.com/science/article/pii/S1097276520300083
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    Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival
    1
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      DOI: 10.1016/j.devcel.2020.04.003

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    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
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      DOI: 10.1016/j.stem.2020.03.002

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  25. elifesciences.org elifesciences.org
    A genetic, genomic, and computational resource for exploring neural circuit function
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      DOI: 10.7554/eLife.50901

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    c-Src Promotes Tumorigenesis and Tumor Progression by Activating PFKFB3
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  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions
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      DOI: 10.7554/eLife.49894

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    A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin
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      DOI: 10.1016/j.molcel.2019.12.019

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    Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner
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  30. www.eneuro.org www.eneuro.org
    Functional Assessment In Vivo of the Mouse Homologue of the Human Ala-9-Ser NHE6 Variant
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      DOI: 10.1523/ENEURO.0046-19.2019

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    Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis
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      DOI: 10.1016/j.chembiol.2020.04.003

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    Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36
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    Peroxisome Elevation Induces Stem Cell Differentiation and Intestinal Epithelial Repair
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  34. genesdev.cshlp.org genesdev.cshlp.org
    Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne
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      DOI: 10.1101/gad.332395.119

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  35. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    RNF20 Functions as a Transcriptional Coactivator for PPARγ by Promoting NCoR1 Degradation in Adipocytes
    1
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      DOI: 10.2337/db19-0508

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  36. www.mdpi.com www.mdpi.com
    Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling
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      HA-tag

      DOI: 10.3390/ijms21051773

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    Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
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      DOI: 10.1016/j.cmet.2020.03.010

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  38. www.mdpi.com www.mdpi.com
    HUNK Phosphorylates Rubicon to Support Autophagy
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      anti-HA

      DOI: 10.3390/ijms20225813

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    Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1
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      anti-HA

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  40. www.jbc.org www.jbc.org
    Molecular mechanisms that regulate export of the planar cell-polarity protein Frizzled-6 out of the endoplasmic reticulum
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    Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
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    Non-canonical Receptive Field Properties and Neuromodulation of Feature-Detecting Neurons in Flies
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  43. Aug 2020
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    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
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    A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at the trans-Golgi network
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    Protein arginine methyltransferase 1 interacts with PGC1α and modulates thermogenic fat activation
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    Anterior Cingulate Cortex to Ventral Hippocampus Circuit Mediates Contextual Fear Generalization
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    HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70
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    Sleep Regulation by Neurotensinergic Neurons in a Thalamo-Amygdala Circuit
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    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
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    IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation
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    Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis
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    STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition
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    SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing
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    Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition
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    Visualization of Protein Sorting at the Trans-Golgi Network and Endosomes Through Super-Resolution Imaging
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    Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
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    Metabolic Rewiring in Response to Biguanides Is Mediated by mROS/HIF-1a in Malignant Lymphocytes
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    DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters
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    Mitotic Implantation of the Transcription Factor Prospero via Phase Separation Drives Terminal Neuronal Differentiation
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    Dopamine Signaling in the Suprachiasmatic Nucleus Enables Weight Gain Associated with Hedonic Feeding
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    Optical Pooled Screens in Human Cells
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    Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels
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    Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder
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    KCC2 Regulates Neuronal Excitability and Hippocampal Activity via Interaction with Task-3 Channels
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    Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation
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    A ZDHHC5-GOLGA7 Protein Acyltransferase Complex Promotes Nonapoptotic Cell Death
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    Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
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    Compartmentalized cAMP Generation by Engineered Photoactivated Adenylyl Cyclases
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    Chemogenetic Inhibition of the Amygdala Modulates Emotional Behavior Expression in Infant Rhesus Monkeys
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    Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
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    Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss
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    Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch
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    Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination
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    α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development
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    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection
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    The Translational Landscape of the Human Heart
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    Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions
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    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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    Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes
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    AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity
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    A Critical Neurodevelopmental Role for L-Type Voltage-Gated Calcium Channels in Neurite Extension and Radial Migration
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    Impeding Transcription of Expanded Microsatellite Repeats by Deactivated Cas9
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    Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila
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    The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification
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    Neuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons
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    Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy
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    Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH
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    Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.
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    Fbxl4 Serves as a Clock Output Molecule that Regulates Sleep through Promotion of Rhythmic Degradation of the GABAA Receptor
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    Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium
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    Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes
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    Novel Mutation of the RUNX2 Gene in Patients with Cleidocranial Dysplasia
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    Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation
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    Direct Midbrain Dopamine Input to the Suprachiasmatic Nucleus Accelerates Circadian Entrainment
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    sciencedirect.com/science/article/pii/S0960982217308576
  164. elifesciences.org elifesciences.org
    Ciliomotor circuitry underlying whole-body coordination of ciliary activity in the Platynereis larva
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      RRID:AB_1549585

      Curator: @chewbeccax

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    elifesciences.org/articles/26000
  165. www.sciencedirect.com www.sciencedirect.com
    Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses
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      AB_1549585

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1931312817302032
  166. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis
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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1074761317302789
  167. www.sciencedirect.com www.sciencedirect.com
    Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms
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    sciencedirect.com/science/article/pii/S0092867417306943
  168. www.sciencedirect.com www.sciencedirect.com
    Feature Integration Drives Probabilistic Behavior in the Drosophila Escape Response
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    sciencedirect.com/science/article/pii/S0896627317304749
  169. www.sciencedirect.com www.sciencedirect.com
    Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development
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    sciencedirect.com/science/article/pii/S1534580717303957
  170. www.sciencedirect.com www.sciencedirect.com
    Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
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      Curator: @kaitlinsung

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    sciencedirect.com/science/article/pii/S1535610817301599
  171. elifesciences.org elifesciences.org
    RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity
    2
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      Curator: @Zeljana_Babic

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    elifesciences.org/articles/18496
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
    1
    1. scibot 08 Nov 2017
      3724

      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC4931344/
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDK Substrate Phosphorylation and Ordering the Cell Cycle
    2
    1. scibot 08 Nov 2017
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      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC5161751/table/undtbl1/
  174. www.sciencedirect.com www.sciencedirect.com
    CDK Substrate Phosphorylation and Ordering the Cell Cycle
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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0092867416316063
  175. www.sciencedirect.com www.sciencedirect.com
    Agonist-Evoked Ca2+ Signaling in Enteric Glia Drives Neural Programs That Regulate Intestinal Motility in Mice
    1
    1. scibot 08 Nov 2017
      AB_1549585

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S2352345X15001496
  176. www.sciencedirect.com www.sciencedirect.com
    A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior
    1
    1. scibot 08 Nov 2017
      AB_1549585

      Curator: @jcabotaj

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    sciencedirect.com/science/article/pii/S0896627315002895
  177. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuroarchitecture and neuroanatomy of the Drosophila central complex: A GAL4‐based dissection of protocerebral bridge neurons and circuits
    1
    1. scibot 08 Nov 2017
      AB_1549585

      Curator: @jcabotaj

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.23705