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  1. Aug 2021
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules
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    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
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    Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease
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    Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling
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    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
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    TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate
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    Gestational Diabetes Epigenetically Reprograms the Cart Promoter in Fetal Ovary, Causing Subfertility in Adult Life
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    The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
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  22. Jul 2021
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    The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality
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    SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States
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    Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia
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    A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus
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    Thyroid Hormone Receptor β Suppression of RUNX2 is Mediated by Brahma Related Gene 1 Dependent Chromatin Remodeling
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    Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency
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    AML Subtype Is a Major Determinant of the Association between Prognostic Gene Expression Signatures and Their Clinical Significance
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    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
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    Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy
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    Protocol to apply spike-in ChIP-seq to capture massive histone acetylation in human cells
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    Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation
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    Mapping the residue specificities of epigenome enzymes by yeast surface display
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    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
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      AB_4729

      DOI: 10.1016/j.molcel.2021.06.020

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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation
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      DOI: 10.1016/j.isci.2021.102660

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    DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity
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      RRID:AB_2118291

      DOI: 10.1016/j.celrep.2021.109281

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    STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
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    A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
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      DOI: 10.1016/j.immuni.2021.05.016

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    Muscle regeneration controlled by a designated DNA dioxygenase
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      ab4729

      DOI: 10.1038/s41419-021-03817-2

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  51. May 2021
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    Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome
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      DOI: 10.1016/j.celrep.2021.109161

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  53. www.sciencedirect.com www.sciencedirect.com
    Phase separation of OCT4 controls TAD reorganization to promote cell fate transitions
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      DOI: 10.1016/j.stem.2021.04.023

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    Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
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    Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
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      DOI: 10.1016/j.molcel.2021.04.015

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    A protocol for rapid degradation of endogenous transcription factors in mammalian cells and identification of direct regulatory targets
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    Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8
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      DOI: 10.1016/j.celrep.2021.109143

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    Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML
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    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
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    Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
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      DOI: 10.1016/j.stem.2020.06.005

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    An Activity-Mediated Transition in Transcription in Early Postnatal Neurons
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      DOI: 10.1016/j.neuron.2020.06.008

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    Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release
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      DOI: 10.1016/j.molcel.2021.03.008

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    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
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      DOI: 10.1016/j.molcel.2021.01.010

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    Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage
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      RRID:AB_2118291

      DOI: 10.1016/j.molcel.2020.10.036

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    Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases
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      DOI: 10.1016/j.molcel.2020.06.007

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    Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
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      DOI: 10.1016/j.molcel.2020.04.027

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    Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells
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      DOI: 10.1016/j.immuni.2020.09.008

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    Genome‐Wide Estrogen Receptor β Chromatin Binding in Human Colon Cancer Cells Reveals its Tumor Suppressor Activity
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      RRID:AB_2118291

      DOI: 10.1002/ijc.33573

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33573
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    Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates
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      DOI: 10.1016/j.devcel.2020.07.006

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    Folding Keratin Gene Clusters during Skin Regional Specification
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    H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization
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    sciencedirect.com/science/article/pii/S1097276521001428
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    The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
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    sciencedirect.com/science/article/pii/S1097276521003142
  73. Apr 2021
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    STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma
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      DOI: 10.1016/j.ccell.2021.04.001

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    Principles of signaling pathway modulation for enhancing human naive pluripotency induction
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    B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells
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      DOI: 10.1016/j.cell.2021.02.015

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    sciencedirect.com/science/article/pii/S0092867421001653
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    Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease
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    A compendium and comparative epigenomics analysis of cis -regulatory elements in the pig genome
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      DOI: 10.1038/s41467-021-22448-x

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    Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1
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    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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    Multi-omic profiling of pituitary thyrotropic cells and progenitors
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      DOI: 10.1186/s12915-021-01009-0

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    TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation
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    MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity
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      DOI: 10.1038/s41419-021-03647-2

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    Deficiency of histone methyltransferase SETD2 in liver leads to abnormal lipid metabolism and hepatocarcinoma
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      DOI: 10.1002/hep.31594

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  85. Mar 2021
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    Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma
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    Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory
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      DOI: 10.1016/j.neuron.2021.01.005

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  88. Feb 2021
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    Targeted degradation of the enhancer lysine acetyltransferases CBP and p300
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    Characterization of Organoid Cultures to Study the Effects of Pregnancy Hormones on the Epigenome and Transcriptional Output of Mammary Epithelial Cells
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    Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma
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    Integrated multi-omics reveal epigenomic disturbance of assisted reproductive technologies in human offspring
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    Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG
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    Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells
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    Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation
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    KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer
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  134. elifesciences.org elifesciences.org
    KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
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    Oct4-Mediated Inhibition of Lsd1 Activity Promotes the Active and Primed State of Pluripotency Enhancers
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    Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution
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  137. academic.oup.com academic.oup.com
    De novo PacBio long-read and phased avian genome assemblies correct and add to reference genes generated with intermediate and short reads
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    Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma
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      Histone H3 (acetyl K27) rabbit pAb (ChIP grade)

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    The Histone Chaperone FACT Induces Cas9 Multi-turnover Behavior and Modifies Genome Manipulation in Human Cells
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    The enhancer RNA lnc-SLC4A1-1 epigenetically regulates unexplained recurrent pregnancy loss (URPL) by activating CXCL8 and NF-kB pathway
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      DOI: 10.1016/j.ebiom.2018.11.015

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  142. Jan 2020
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    Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4
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      DOI: 10.1016/j.celrep.2019.10.026

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    CoBATCH for High-Throughput Single-Cell Epigenomic Profiling
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    A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling
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      DOI: 10.1016/j.stem.2019.06.008

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    A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers
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      DOI: 10.1016/j.cell.2019.07.011

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    Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma
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    Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury
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      DOI: 10.1016/j.immuni.2019.11.013

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    An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
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    Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet
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      DOI: 10.1016/j.molcel.2019.10.007

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    Nucleome Dynamics during Retinal Development
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      DOI: 10.1016/j.neuron.2019.08.002

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    The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers
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      DOI: 10.1016/j.chom.2019.08.010

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    H3K4me1 Supports Memory-like NK Cells Induced by Systemic Inflammation
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      DOI: 10.1016/j.celrep.2019.11.043

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    The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma
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      DOI: 10.1016/j.ccell.2018.05.002

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    Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses
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      DOI: 10.1016/j.immuni.2019.05.006

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    SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring
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      DOI: 10.1016/j.neuron.2019.07.013

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    Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells
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    The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair
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      DOI: 10.1016/j.immuni.2019.06.005

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    Organization of Chromatin by Intrinsic and Regulated Phase Separation
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      DOI: 10.1016/j.cell.2019.08.037

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    Bone marrow stromal cells transcriptionally repress ESR1 but cannot overcome constitutive ESR1 mutant activity
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      DOI: 10.1210/en.2019-00299

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    Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation
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    ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures
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    Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle
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      DOI: 10.7554/eLife.50087

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    The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
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    MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition
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    PRC2-Associated Chromatin Contacts in the Developing Limb Reveal a Possible Mechanism for the Atypical Role of PRC2 in HoxA Gene Expression
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    Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity
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      DOI: 10.1016/j.stem.2019.04.021

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    Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases
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      DOI: 10.1016/j.immuni.2019.09.021

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    Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors
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    Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance
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    Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
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      DOI: 10.1016/j.cell.2019.10.044

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    Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf
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    Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
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    Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function
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    Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition
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    Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation
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    Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4
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    The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis
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    BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models
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    Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts
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    Stem Cell Proliferation Is Kept in Check by the Chromatin Regulators Kismet/CHD7/CHD8 and Trr/MLL3/4
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    Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease
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