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    Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers
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    EFA6A, an Exchange Factor for Arf6, Regulates NGF-Dependent TrkA Recycling From Early Endosomes and Neurite Outgrowth in PC12 Cells
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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  5. May 2024
  6. 52.53.155.43 52.53.155.43
    2024.02.09.579580v1.full-html.html
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    Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders
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    cell.com/iscience/abstract/S2589-0042(24)01024-1
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    The phosphorylation landscape of infection-related development by the rice blast fungus
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    Contrasting consequences of podocyte IGF1R inhibition
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    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
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    Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor
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      Cell Signaling, 4370

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    Identification of novel and distinct FGF23 signaling in a Klotho-dependent and -independent manner
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    JNEUROSCI.0136-24.2024.full-html.html
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    Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma
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  15. Apr 2024
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    Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling
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    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
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    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
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    Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer
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    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    sciencedirect.com/science/article/pii/S0006295224002132
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    The complete Kaposi sarcoma-associated herpesvirus genome induces early-onset, metastatic angiosarcoma in transgenic mice
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    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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    Sustained ERK signaling promotes G2 cell cycle exit and primes cells for whole-genome duplication
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    ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
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    SWI/SNF complex-mediated chromatin remodelling in Candida glabrata promotes immune evasion
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    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle
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    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
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    A light-controlled phospholipase C for imaging of lipid dynamics and controlling neural plasticity
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling
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    A receptor required for chitin perception facilitates arbuscular mycorrhizal associations and distinguishes root symbiosis from immunity
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    Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
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  34. Mar 2024
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    S-nitrosylation-triggered unfolded protein response maintains hematopoietic progenitors in Drosophila
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    Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion
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    Nanodrug-bacteria conjugates-mediated oncogenic collagen depletion enhances immune checkpoint blockade therapy against pancreatic cancer
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    The effects of Aurora Kinase inhibition on thyroid cancer growth and sensitivity to MAPK-directed therapies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10962586/
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    TGR5-mediated lateral hypothalamus-dCA3-dorsolateral septum circuit regulates depressive-like behavior in male mice
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    Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis
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      anti-pERK1/2

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    Integrated proteogenomic characterization of glioblastoma evolution
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    Metformin inhibits cell proliferation and ACTH secretion in AtT20 cells via regulating the MAPK pathway
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    Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma
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    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
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    A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer
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    High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma
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    Comparative localization of colorectal sensory afferent central projections in the mouse spinal cord dorsal horn and caudal medulla dorsal vagal complex
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    Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection
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    Minichromosome maintenance 6 protects against renal fibrogenesis by regulating DUSP6-mediated ERK/GSK-3β/Snail1 signaling
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    Irisin reduces amyloid-β by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling
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    The MORC2 p.S87L mutation reduces proliferation of pluripotent stem cells derived from a patient with the spinal muscular atrophy-like phenotype by inhibiting proliferation-related signaling pathways
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  161. 52.53.155.43 52.53.155.43
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  162. www.sciencedirect.com www.sciencedirect.com
    Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH
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  163. 52.53.155.43 52.53.155.43
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  164. Jun 2023
  165. 52.53.155.43 52.53.155.43
    TOPK mediates immune evasion of Renal Cell Carcinoma via upregulating the expression of PD-L1
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SHP2 participates in decidualization by activating ERK to maintain normal nuclear localization of progesterone receptor
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    The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Validation of miRNAs as diagnostic and prognostic biomarkers, and possible therapeutic targets in medullary thyroid cancers
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    Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa
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    Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
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    Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer
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    Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design
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    Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development
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    Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
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    UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
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    Discovery of a Selective and Orally Bioavailable FGFR2 Degrader for Treating Gastric Cancer
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate
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  179. dx.doi.org dx.doi.org
    USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis
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    A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia
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    N6-methyl-2′-deoxyadenosine promotes self-renewal of BFU-E progenitor in erythropoiesis
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  182. www.microbiologyresearch.org www.microbiologyresearch.org
    IRAK1 inhibition blocks the HIV-1 RNA mediated pro-inflammatory cytokine response from microglia
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    LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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    Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
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    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
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    Casein kinase 1α regulates testosterone synthesis and testis development in adult mice
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  192. 52.53.155.43 52.53.155.43
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  193. www.jneurosci.org www.jneurosci.org
    Chronic neuronal inactivity utilizes the mTOR-TFEB pathway to drive transcription-dependent autophagy for homeostatic up-scaling
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth
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  196. www.sciencedirect.com www.sciencedirect.com
    ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
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