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  1. Jan 2020
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    Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma
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    Potassium and glutamate transport is impaired in scar-forming tumor-associated astrocytes
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    Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy
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    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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    Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation
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    The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death
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    VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance
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    let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7
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    A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration
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    Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development
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    Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development
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    miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer
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    Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice
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    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
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    Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain
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    The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes
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    Autophagy is essential for oligodendrocyte differentiation, survival, and proper myelination
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    GABAergic Restriction of Network Dynamics Regulates Interneuron Survival in the Developing Cortex
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    Microglia mediate HIV-1 gp120-induced synaptic degeneration in spinal pain neural circuits
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    Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses
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    DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon Survival Factors and Promote SARM1-Dependent Axon Degeneration
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      DOI: 10.1007/s12035-019-01796-2

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    Light-at-night exposure affects brain development through pineal allopregnanolone-dependent mechanisms
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    Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer’s Disease
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    Early-generated interneurons regulate neuronal circuit formation during early postnatal development
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    The DNA Repair Nuclease MRE11A Functions as a Mitochondrial Protector and Prevents T Cell Pyroptosis and Tissue Inflammation
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    MicroRNA-25-5p counteracts oxidized LDL-induced pathological changes by targeting neuronal growth regulator 1 (NEGR1) in human brain micro-vessel endothelial cells
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    SponGee: A Genetic Tool for Subcellular and Cell-Specific cGMP Manipulation
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    Neuronal Ca2+‐dependent activator protein 1 (NCDAP1) induces neuronal cell death by activating p53 pathway following traumatic brain injury
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    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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    The Gypsy Endogenous Retrovirus Drives Non-Cell-Autonomous Propagation in a Drosophila TDP-43 Model of Neurodegeneration
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    Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
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    Donepezil‐induced oligodendrocyte differentiation is mediated through estrogen receptors
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    Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2
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      DOI: 10.15252/embr.201947845

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    A dual‐functional memantine nitrate MN‐08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid hemorrhage models
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    UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses
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    A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas
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    Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents
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    Early treatment with C1 esterase inhibitor improves weight but not memory deficits in a rat model of status epilepticus
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      DOI: 10.1016/j.physbeh.2019.112705

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    N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration
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    Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis
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    Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function
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    Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover
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    A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
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    Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation
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    Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis
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    Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer
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    AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration
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    Screening the expression of several miRNAs from TaqMan Low Density Array in traumatic brain injury: miR‐219a‐5p regulates neuronal apoptosis by modulating CCNA2 and CACUL1
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    Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function
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    Chromatin Environment and Cellular Context Specify Compensatory Activity of Paralogous MEF2 Transcription Factors
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    IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer
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    Necroptosis and Apoptosis Contribute to Cisplatin and Aminoglycoside Ototoxicity
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    Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets
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    Injured Axons Instruct Schwann Cells to Build Constricting Actin Spheres to Accelerate Axonal Disintegration
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    Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse
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    N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis
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    Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis
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    A Tissue- and Temporal-Specific Autophagic Switch Controls Drosophila Pre-metamorphic Nutritional Checkpoints
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    Augmenting the therapeutic efficacy of adenosine against pancreatic cancer by switching the Akt/p21-dependent senescence to apoptosis
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    Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer
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    Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers
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    Control of Intestinal Cell Fate by Dynamic Mitotic Spindle Repositioning Influences Epithelial Homeostasis and Longevity
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    Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease
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    Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors
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    Protective effects of delayed intraventricular TLR7 agonist administration on cerebral white and gray matter following asphyxia in the preterm fetal sheep
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    Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration
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    WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis
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    3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival
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    Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness
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    Modeling Patient-Derived Glioblastoma with Cerebral Organoids
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    Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity
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    Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory
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    Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy
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    Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses
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    A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in a spider
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    Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification
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    Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells
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    Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer
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    Chromosomal Instability Induces Cellular Invasion in Epithelial Tissues
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    The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells
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    PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ
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    Type 2 Diabetes Leads to Axon Initial Segment Shortening in db/db Mice
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    UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F
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    Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice
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    Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia
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    iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding
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    Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling
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    Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis
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    Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism
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    mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis
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    TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer
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    GRP94 Is an Essential Regulator of Pancreatic β-Cell Development, Mass, and Function in Male Mice
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