1,238 Matching Annotations
  1. Jun 2023
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    Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation
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    sciencedirect.com/science/article/pii/S1097276523003763
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    WeiTsing, a pericycle-expressed ion channel, safeguards the stele to confer clubroot resistance
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    sciencedirect.com/science/article/pii/S0092867423005421
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    Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility
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    sciencedirect.com/science/article/pii/S0092867423005287
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    The lipid flippase ATP10B enables cellular lipid uptake under stress conditions
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    biorxiv.org/content/10.1101/2023.06.01.543059v1
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    Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice
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    sciencedirect.com/science/article/pii/S153458072300237X
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    APOE expression and secretion are modulated by mitochondrial dysfunction
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    ncbi.nlm.nih.gov/pmc/articles/PMC10231934/
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    Host genetics highlights IFN-γ-dependent Toxoplasma genes encoding secreted and non-secreted virulence factors in in vivo CRISPR screens
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    sciencedirect.com/science/article/pii/S2211124723006034
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    Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in severe patients with COVID-19
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    sciencedirect.com/science/article/pii/S2589004223010064
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    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
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    sciencedirect.com/science/article/pii/S2211124723005909
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    The Rab5 effector FERRY links early endosomes with mRNA localization
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    Coupling between GPR143 and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L-3,4-dihydroxyphenylalanine in the dorsal striatum
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15789
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    PKCδ regulates chromatin remodeling and DNA repair through SIRT6
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    biorxiv.org/content/10.1101/2023.05.24.541991v1
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    LEAFY homeostasis is regulated via ubiquitin-dependent degradation and sequestration in cytoplasmic condensates
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  15. May 2023
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    EWSR1 maintains centromere identity
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    “Disruption of Golgi markers by two RILP-directed shRNAs in neurons: a new role for RILP or a neuron-specific off-target phenotype?”
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    Antagonistic interactions among structured domains in the multivalent Bicc1-ANKS3-ANKS6 protein network govern phase transitioning of target mRNAs
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    Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila
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    Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction
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      DOI: 10.7554/eLife.82057

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    ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
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      DOI: 10.1038/s41467-023-38605-3

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    Functional coordination between transcription factor clustering and gene activity
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    sciencedirect.com/science/article/pii/S1097276523002897
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    MYO10 regulates genome stability and cancer inflammation through mediating mitosis
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    Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells
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    A phospho-switch constrains BTL2-mediated phytocytokine signaling in plant immunity
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    sciencedirect.com/science/article/pii/S0092867423004233
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    LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma
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    Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway
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    Neurobeachin controls the asymmetric subcellular distribution of electrical synapse proteins
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    HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways
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    AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity
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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PASK links cellular energy metabolism with a mitotic self-renewal network to establish differentiation competence
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      DOI: 10.7554/eLife.81717

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    ncbi.nlm.nih.gov/pmc/articles/PMC10162801/
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    A ubiquitin fusion reporter to monitor muscle proteostasis in C. elegans
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  33. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Fluid shear stress generates a unique signaling response by activating multiple TGFβ family type I receptors in osteocytes
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    Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2
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  35. Apr 2023
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    Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis
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    DNA-initiated epigenetic cascades driven by C9orf72 hexanucleotide repeat
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    Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
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    A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading
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    Fluorescence-resonance-energy-transfer-based assay to estimate modulation of TDP1 activity through arginine methylation
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    sciencedirect.com/science/article/pii/S2666166723001764
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    DTX3L E3 ligase targets p53 for degradation at poly ADP-ribose polymerase-associated DNA damage sites
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    Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development
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    sciencedirect.com/science/article/pii/S1534580723001326
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    MeCP2 Represses the Activity of Topoisomerase IIβ in Long Neuronal Genes
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    Conformational changes in the negative arm of the circadian clock correlate with dynamic interactomes involved in post-transcriptional regulation
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    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
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    The length of FOXE1 polyalanine tract in congenital hypothyroidism: Evidence for a pathogenic role from familial, molecular and cohort studies
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    HNRNPU facilitates antibody class-switch recombination through C-NHEJ promotion and R-loop suppression
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    The Ubiquitin-specific Protease USP36 Associates with the Microprocessor Complex and Regulates miRNA Biogenesis by SUMOylating DGCR8
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    Seasonal cues act through the circadian clock and pigment-dispersing factor to control EYES ABSENT and downstream physiological changes
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    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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    Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8
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    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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    The Scaffolding Function of LSD1/KDM1A Reinforces a Negative Feedback Loop to Repress Stem Cell Gene Expression during Primitive Hematopoiesis
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    AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity
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    Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy
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    SLC46A3 is a lysosomal proton-coupled steroid conjugate and bile acid transporter involved in transport of active catabolites of T-DM1
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    Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2
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