1,669 Matching Annotations
  1. Jan 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Protocol to measure centrosome cohesion deficits mediated by pathogenic LRRK2 in cultured cells using confocal microscopy
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    sciencedirect.com/science/article/pii/S2666166722009042
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    The NLRP1 and CARD8 inflammasomes detect reductive stress
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    sciencedirect.com/science/article/pii/S2211124722018708
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    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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    ncbi.nlm.nih.gov/pmc/articles/PMC9839780/
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    Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration
    1
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      DOI: 10.7554/eLife.80533

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    ncbi.nlm.nih.gov/pmc/articles/PMC9831603/
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    Human SMARCA5 is continuously required to maintain nucleosome spacing
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    sciencedirect.com/science/article/pii/S1097276522011753
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    The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9306355/
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    Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
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    Evolutionarily conserved regulators of tau identify targets for new therapies
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    sciencedirect.com/science/article/pii/S0896627322010856
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    The human pre-replication complex is an open complex
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    sciencedirect.com/science/article/pii/S0092867422015215
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    A central role for regulated protein stability in the control of TFE3 and MITF by nutrients
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    sciencedirect.com/science/article/pii/S1097276522011704
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    Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy
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    Two modes of Cue2-mediated mRNA cleavage with distinct substrate recognition initiate no-go decay
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1172/6965460
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    The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation
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    sciencedirect.com/science/article/pii/S2211124722018058
  15. Dec 2022
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    POU1F1/Pou1f1 c.143-83A > G variant disrupts the branch site in pre-mRNA and leads dwarfism
    1
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      DOI: 10.1210/endocr/bqac198

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    The ADP-ribose hydrolase NUDT5 is important for DNA repair
    1
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    The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model
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    sciencedirect.com/science/article/pii/S2211124722017296
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    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    sciencedirect.com/science/article/pii/S2211124722017260
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    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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    sciencedirect.com/science/article/pii/S1534580722008152
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    Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines
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    Epidermal stratification requires retromer-mediated desmoglein-1 recycling
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    Elongation factor-specific capture of RNA polymerase II complexes
    1
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    PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing
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    sciencedirect.com/science/article/pii/S1097276522010991
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    Mitochondrial cristae architecture protects against mtDNA release and inflammation
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    Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics
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      DOI: 10.1111/jnc.15726

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    IFT-A structure reveals carriages for membrane protein transport into cilia
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    sciencedirect.com/science/article/pii/S0092867422014222
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9713376/
  29. www.nature.com www.nature.com
    Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice
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      DOI: 10.1038/s41401-022-01024-z

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  30. Nov 2022
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcm2 promotes stem cell differentiation via its ability to bind H3-H4
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    The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2
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    Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression
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    Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq
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    FEBS Press
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication
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      DOI: 10.1080/15548627.2021.1999561

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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
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    Purification of exosome-enriched proteins produced in a Drosophila cell line by size exclusion chromatography
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    sciencedirect.com/science/article/pii/S2666166722007146
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    CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors
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      DOI: 10.1016/j.neuron.2022.10.018

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    LncRNA CCTT-mediated RNA-DNA and RNA-protein interactions facilitate the recruitment of CENP-C to centromeric DNA during kinetochore assembly
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    Cancer cell intrinsic TIM-3 induces glioblastoma progression
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    V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
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    Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
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    An enChIP system for the analysis of genome functions in budding yeast
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    Structure and functionality of a multimeric human COQ7:COQ9 complex
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    Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity
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    METTL3 regulates m6A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma
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    A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation
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    Allelic variation in the Arabidopsis TNL CHS3/CSA1 immune receptor pair reveals two functional cell-death regulatory modes
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    Continuous double-strand break induction and their differential processing sustain chiasma formation during Caenorhabditis elegans meiosis
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    A family of C. elegans VASA homologs control Argonaute pathway specificity and promote transgenerational silencing
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    Integrative RNA-omics discovers GNAS alternative splicing as a phenotypic driver of splicing factor-mutant neoplasms
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    Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain
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    Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function
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    Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis
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    CaMKII binds both substrates and activators at the active site
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    Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA
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    Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism
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    The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex
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    FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity
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  132. Jun 2022
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    Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses
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    MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines
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    Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion
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    cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model
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    Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement
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    Tandem immuno-purification of affinity-tagged proteins from mouse testis extracts for MS analysis
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    UBP12 and UBP13 deubiquitinases destabilize the CRY2 blue light receptor to regulate Arabidopsis growth
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    TRPV1 SUMOylation suppresses itch by inhibiting TRPV1 interaction with H1 receptors
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    Time-resolved Phosphoproteome and Proteome Analysis Reveals Kinase Signalling on Master Transcription Factors During Myogenesis
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    Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome
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    An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates
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    γ-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor
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  147. May 2022
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    DDX41 is required for cGAS-STING activation against DNA virus infection
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    ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
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    C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
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    Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15
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    Mutations in DNA binding domain of p53 impede RSL1D1-p53 interaction to escape from degradation in human colorectal cancer cells
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    Chromatin remodeling is restricted by transient GATA6 binding during iPSC differentiation to definitive endoderm
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    Study of novel NARS2 variants in patient of combined oxidative phosphorylation deficiency 24
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    Quantitative analysis of protein-RNA interactions in fission yeast
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    Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response
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    Adipose mitochondrial metabolism controls body growth by modulating systemic cytokine and insulin signaling
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    Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
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    BAG6 prevents the aggregation of neurodegeneration-associated fragments of TDP43
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    Gene regulatory networks shape developmental plasticity of root cell types under water extremes in rice
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    ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer
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    Generation of RYBP FLAG-HA knock-in human embryonic stem cell line through CRISPR/Cas9-mediated homologous recombination
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    The Mettl3 epitranscriptomic writer amplifies p53 stress responses
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  166. Apr 2022
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    Characterization and functional interrogation of the SARS-CoV-2 RNA interactome
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    Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells
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    Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity
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    Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation
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    CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming
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    Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
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    GFI1 cooperates with IKZF1/IKAROS to activate gene expression in T-cell acute lymphoblastic leukemia
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    The roles of RNA helicases in DNA damage repair and tumorigenesis reveal precision therapeutic strategies
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Labeling of heterochronic ribosomes reveals C1ORF109 and SPATA5 control a late step in human ribosome assembly
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    A local insulin reservoir in Drosophila alpha cell homologs ensures developmental progression under nutrient shortage
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    RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin
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    Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense
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    Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development
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    Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML
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    Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    1. scibot 02 Mar 2022
      Sigma-aldrich Cat#F1804

      DOI: 10.1016/j.scr.2022.102724

      Resource: (Sigma-Aldrich Cat# F1804, RRID:AB_262044)

      Curator: @sophiastull

      SciCrunch record: RRID:AB_262044

      What is this?
      RRID:AB_262044
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    sciencedirect.com/science/article/pii/S1873506122000733