280 Matching Annotations
  1. Last 7 days
  2. 52.53.155.43 52.53.155.43
    Pharmacological Activation of TRPC6 Channel Prevents Colitis Progression.
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    1. scibot 17 May 2024
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      DOI: 10.20944/preprints202402.0113.v1

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    Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis
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    sciencedirect.com/science/article/pii/S153561082400134X
  4. May 2024
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    Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor
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    sciencedirect.com/science/article/pii/S1934590924001383
  6. Apr 2024
  7. 52.53.155.43 52.53.155.43
    Mechanical strengthening of cell-cell adhesion during mouse embryo compaction
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    1. scibot 05 Apr 2024
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  8. Mar 2024
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    Dissecting Gene Expression Networks in the Developing Hippocampus through the Lens of NEIL3 Depletion
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    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.pneurobio.2024.102599

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    sciencedirect.com/science/article/pii/S0301008224000352
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    A unique chaperoning mechanism in class A JDPs recognizes and stabilizes mutant p53
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    sciencedirect.com/science/article/pii/S1097276524001370
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    SOX17/ETV2 improves the direct reprogramming of adult fibroblasts to endothelial cells
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    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.crmeth.2024.100732

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    sciencedirect.com/science/article/pii/S2667237524000572
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    Pathophysiology of chikungunya virus infection associated with fatal outcomes
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    sciencedirect.com/science/article/pii/S1931312824000544
  13. 52.53.155.43 52.53.155.43
    Characterization of novel PHEX variants in X-linked hypophosphatemic rickets and genotype-PHEX activity correlation
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    1. scibot 08 Mar 2024
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      DOI: 10.1210/clinem/dgae120

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    A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate
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    sciencedirect.com/science/article/pii/S193459092400047X
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    GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism
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    1. scibot 07 Mar 2024
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    sciencedirect.com/science/article/pii/S258900422400467X
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    Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology
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    sciencedirect.com/science/article/pii/S1097276524000959
  17. Feb 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Activation of TRPC6 Channel Prevents Colitis Progression
    1
    1. scibot 28 Feb 2024
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      DOI: 10.3390/ijms25042401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10889536/
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    Metabolic rescue of α-synuclein-induced neurodegeneration through propionate supplementation and intestine-neuron signaling in C. elegans
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    1. scibot 27 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001931
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    Generation of an induced pluripotent stem cell line (SYSUSCi004-A) from a patient with Infantile Malignant Osteopetrosis
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    sciencedirect.com/science/article/pii/S187350612400028X
  21. www.biorxiv.org www.biorxiv.org
    Expansion of the neocortex and protection from neurodegeneration by in vivo transient reprogramming
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1101/2023.11.27.568858

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    biorxiv.org/content/10.1101/2023.11.27.568858v1
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic cell-adhesion molecule latrophilin-2 is differentially directed to dendritic domains of hippocampal neurons
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    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108799

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    ncbi.nlm.nih.gov/pmc/articles/PMC10839266/
  23. Jan 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing
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    sciencedirect.com/science/article/pii/S2211124724000329
  25. www.tandfonline.com www.tandfonline.com
    Enhanced neuroprotective activity of ophthalmic delivered nerve growth factor conjugated with cell penetrating peptide against optic nerve injury
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      DOI: 10.1080/1061186X.2023.2295220

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    tandfonline.com/doi/abs/10.1080/1061186X.2023.2295220
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    CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis
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    sciencedirect.com/science/article/pii/S2211124723016194
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    Dynamic IL-6R/STAT3 signaling leads to heterogeneity of metabolic phenotype in pancreatic ductal adenocarcinoma cells
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    sciencedirect.com/science/article/pii/S2211124723016248
  28. Dec 2023
  29. www.embopress.org www.embopress.org
    The EMBO Journal - 2023 - Pelzer - Cell fragmentation in mouse preimplantation embryos induced by ectopic activation of the-html.html
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      DOI: 10.15252/embj.2023114415

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    Two-phase kinetics and cell cortex elastic behavior in Xenopus gastrula cell-cell adhesion
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      DOI: 10.1016/j.devcel.2023.11.014

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    sciencedirect.com/science/article/pii/S1534580723006123
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    Protocol for evaluating mitochondrial morphology changes in response to CCCP-induced stress through open-source image processing software
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    sciencedirect.com/science/article/pii/S2666166723007128
  32. Nov 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Nanoscale organization of the endogenous ASC speck
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    sciencedirect.com/science/article/pii/S2589004223024598
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    PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
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    sciencedirect.com/science/article/pii/S2211124723014262
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    Entorhinohippocampal cholecystokinin modulates spatial learning by facilitating neuroplasticity of hippocampal CA3-CA1 synapses
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    sciencedirect.com/science/article/pii/S2211124723014791
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    Reorganization of adolescent prefrontal cortex circuitry is required for mouse cognitive maturation
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      DOI: 10.1016/j.neuron.2023.10.024

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    sciencedirect.com/science/article/pii/S089662732300805X
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Long-term recruitment of peripheral immune cells to brain scars after a neonatal insult
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      DOI: 10.1002/glia.24490

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    onlinelibrary.wiley.com/doi/10.1002/glia.24490
  38. www.sciencedirect.com www.sciencedirect.com
    Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidation
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    The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing
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    sciencedirect.com/science/article/pii/S2211124723013591
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    Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins
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      DOI: 10.1016/j.xcrm.2023.101255

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    sciencedirect.com/science/article/pii/S2666379123004329
  41. Oct 2023
  42. www.sciencedirect.com www.sciencedirect.com
    High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma
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      DOI: 10.1016/j.xcrm.2023.101244

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    sciencedirect.com/science/article/pii/S2666379123004214
  43. www.medrxiv.org www.medrxiv.org
    Human Motor Endplate Survival after Chronic Peripheral Nerve Injury
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1101/2023.10.12.23296760

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    medrxiv.org/content/10.1101/2023.10.12.23296760v1
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    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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      DOI: 10.1016/j.celrep.2023.113198

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  45. 52.53.155.43 52.53.155.43
    BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice
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      DOI: 10.1210/endocr/bqad152

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    Peroxisomal ERK mediates Akh/glucagon action and glycemic control
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    Melanocortin-3 receptor expression in AgRP neurons is required for normal activation of the neurons in response to energy deficiency
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    Spatiotemporal modeling of chemoresistance evolution in breast tumors uncovers dependencies on SLC38A7 and SLC46A1
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    Dendritic atoh1a+ cells serve as transient intermediates during zebrafish Merkel cell development and regeneration
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    Comprehensive sub-mitochondrial protein map of the parasitic protist Trypanosoma brucei defines critical features of organellar biology
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    Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits
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    Blockade of endogenous insulin receptor signaling in the nucleus tractus solitarius potentiates exercise pressor reflex function in healthy male rats
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    PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity
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  58. Jul 2023
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    PGAM5 is an MFN2 phosphatase that plays an essential role in the regulation of mitochondrial dynamics
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    Organ function is preserved despite reorganization of niche architecture in the hair follicle
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    Cell Competition Shapes Metastatic Latency and Relapse
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  63. Jun 2023
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    Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response
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    Kinesin-5 inhibition improves neural regeneration in experimental autoimmune neuritis
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    Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2
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    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
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  68. journals.biologists.com journals.biologists.com
    Female reproductive dormancy in Drosophila is regulated by DH31-producing neurons projecting into the corpus allatum
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  69. May 2023
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    Kinetics of RTK activation determine ERK reactivation and resistance to dual BRAF/MEK inhibition in melanoma
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    Metamorphic proteins at the basis of human autophagy initiation and lipid transfer
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    Conditional deletion of LRRC8A in the brain reduces stroke damage independently of swelling-activated glutamate release
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    A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice
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    The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging
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    Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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  77. Apr 2023
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    Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling
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    Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
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    Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication
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    Suppression of ferroptosis by vitamin A or antioxidants is essential for neuronal development
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    Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
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    Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
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  85. Mar 2023
  86. www.sciencedirect.com www.sciencedirect.com
    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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    Laminin switches terminal differentiation fate of human trophoblast stem cells under chemically defined culture conditions
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    Autophagy of the somatic stalk cells likely nurses the propagating spores of Dictyostelid social amoebas [version 2; peer review: 2 approved, 1 approved with reservations]
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    Dual role of the P2X7 receptor in dendritic outgrowth during physiological and pathological brain development
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  91. Feb 2023
  92. journals.sagepub.com journals.sagepub.com
    Pyruvate Kinase 2, an Energy Metabolism Related Enzyme, May Have a Neuroprotective Function in Retinal Degeneration
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    Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease
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    A bacteriocyte symbiont determines whitefly sex ratio by regulating mitochondrial function
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    The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
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    Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection
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  98. Jan 2023
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    Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia
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    Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons
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    Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia
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    Periostin activates distinct modules of inflammation and itching downstream of the type 2 inflammation pathway
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    Axonal plasticity in response to active forces generated through magnetic nano-pulling
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    Distinct patterns of RNA polymerase II and transcriptional elongation characterize mammalian genome activation
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    Multiplexed evaluation of mouse wound tissue using oligonucleotide barcoding with single-cell RNA sequencing
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    The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses
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    PDZD8-deficient mice accumulate cholesteryl esters in the brain as a result of impaired lipophagy
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  111. Nov 2022
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    The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2
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    Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS
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    Combined targeting of soluble latent TGF-ß and a solid tumor-associated antigen with adapter CAR T cells
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    The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool
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    NEIL3 contributes to the Fanconi anemia/BRCA pathway by promoting the downstream double-strand break repair step
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    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
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  121. Oct 2022
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    Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer
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    Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome
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    Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord
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    Carbon-nitrogen trading in symbiotic nodules depends on magnesium import
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  135. Aug 2022
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  137. 52.53.155.43 52.53.155.43
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  138. www.sciencedirect.com www.sciencedirect.com
    Increasing cell size remodels the proteome and promotes senescence
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Septin7 is indispensable for proper skeletal muscle architecture and function
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  140. www.sciencedirect.com www.sciencedirect.com
    S-nitrosylation is required for β2AR desensitization and experimental asthma
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    Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes
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  142. Jul 2022
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    Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cells
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    Functional convergence of on-off direction-selective ganglion cells in the visual thalamus
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  148. Jun 2022
  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  150. May 2022
  151. rupress.org rupress.org
    Ribbon boosts ribosomal protein gene expression to coordinate organ form and function
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    DDX41 is required for cGAS-STING activation against DNA virus infection
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  153. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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  154. www.sciencedirect.com www.sciencedirect.com
    Single-cell analysis of human testis aging and correlation with elevated body mass index
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  155. Apr 2022
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    Silencing the odorant receptor co-receptor impairs olfactory reception in a sensillum-specific manner in the cockroach
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    Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB
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    Generation of a human induced pluripotent stem cell (iPSC) line (JUCTCi019-A) from a patient with Charcot-Marie-Tooth disease type 2A2 (CMT2A2) due to a heterozygous missense substitution c.2119C>T (p.Arg707Trp) in MNF2 gene
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    Anatomical distribution and functional roles of electrical synapses in Drosophila
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Assessment of Calcium-Sensing Receptor Variants Confirms Familial Hypocalciuric Hypercalcaemia
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  161. Mar 2022
  162. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Coactivator-associated arginine methyltransferase 1 controls oligodendrocyte differentiation in the corpus callosum during early brain development
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  163. www.nature.com www.nature.com
    The role of the anterior insular during targeted helping behavior in male rats
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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    The ontogenies of endometrial and myometrial leptin and adiponectin receptors in pregnant rats: Their putative impact on uterine contractility
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    Moraxella catarrhalis evades neutrophil oxidative stress responses providing a safer niche for nontypeable Haemophilus influenzae
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering of thick human functional myocardium via static stretching and electrical stimulation
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    Insulin signaling couples growth and early maturation to cholesterol intake in Drosophila
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    Generation of a MSX1 knockout human embryonic stem cell line using CRISPR/Cas9 technology
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    Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state
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    Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
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  173. Feb 2022
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    Mycobacterial infection aggravates Helicobacter pylori-induced gastric preneoplastic pathology by redirection of de novo induced Treg cells
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  175. Jan 2022
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    Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing
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    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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    SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model
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    Mechanical spinal cord transection in larval zebrafish and subsequent whole-mount histological processing
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    Identification of sequence-specific promoters driving polycistronic transcription initiation by RNA polymerase II in trypanosomes
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  181. Dec 2021
  182. www.frontiersin.org www.frontiersin.org
    Extracellular Vesicles Induce an Aggressive Phenotype in Luminal Breast Cancer Cells Via PKM2 Phosphorylation
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    Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling
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    Toxoplasma gondii SAG1 Targeting Host Cell S100A6 for Parasite Invasion and Host Immunity
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    DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons
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    Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage
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    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
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  188. Nov 2021
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    Parahippocampal latrophilin-2 (ADGRL2) expression controls topographical presubiculum to entorhinal cortex circuit connectivity
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    Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying TNNI3 mutations
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  192. Oct 2021
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    Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters
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    Mechanistic Insights into COVID-19 by Global Analysis of the SARS-CoV-2 3CLpro Substrate Degradome
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    PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory
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    Diverse wMel variants of Wolbachia pipientis differentially rescue fertility and cytological defects of the bag of marbles partial loss of function mutation in Drosophila melanogaster
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  199. Sep 2021
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    Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A
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    Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice
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    Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology
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    The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock
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    Repeated nuclear translocations underlie photoreceptor positioning and lamination of the outer nuclear layer in the mammalian retina
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    Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication
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  211. Jul 2021
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    Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA
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    Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
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  217. Jun 2021
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    Generation of two human iPSC lines from patients with autosomal dominant retinitis pigmentosa (UCLi014-A) and autosomal recessive Leber congenital amaurosis (UCLi015-A), associated with RDH12 variants
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    The C-X-C Motif Chemokine Ligand 1 Sustains Breast Cancer Stem Cell Self-Renewal and Promotes Tumor Progression and Immune Escape Programs
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    A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
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    Non-autonomous regulation of germline stem cell proliferation by somatic MPK-1/MAPK activity in C. elegans
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