318 Matching Annotations
  1. Sep 2020
  2. www.sciencedirect.com www.sciencedirect.com
    MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome
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    1. scibot 03 Sep 2020
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      DOI: 10.1016/j.chembiol.2020.02.002

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    sciencedirect.com/science/article/pii/S2451945620300404
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    c-Src Promotes Tumorigenesis and Tumor Progression by Activating PFKFB3
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      DOI: 10.1016/j.celrep.2020.03.005

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    sciencedirect.com/science/article/pii/S221112472030303X
  4. Aug 2020
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin
    1
    1. scibot 17 Aug 2020
      RRID:AB_627268

      DOI: 10.7554/eLife.52779

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    ncbi.nlm.nih.gov/pmc/articles/PMC7112954/
  6. Jan 2020
  7. advances.sciencemag.org advances.sciencemag.org
    Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity
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    1. scibot 13 Jan 2020
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      DOI: 10.1126/sciadv.aau7802

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    advances.sciencemag.org/content/5/9/eaau7802
  8. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of Ci/Gli by Fused Family Kinases Promotes Hedgehog Signaling
    1
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      DOI: 10.1016/j.devcel.2019.06.008

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    sciencedirect.com/science/article/pii/S153458071930526X
  9. www.sciencedirect.com www.sciencedirect.com
    C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex
    1
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      DOI: 10.1016/j.molcel.2019.06.023

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    sciencedirect.com/science/article/pii/S1097276519304794
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Spinophilin regulates phosphorylation and interactions of the GluN2B subunit of the N‐Methyl‐D‐Aspartate Receptor
    1
    1. scibot 13 Jan 2020
      RRID:AB_627268

      DOI: 10.1111/jnc.14831

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14831
  11. www.mdpi.com www.mdpi.com
    N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor
    1
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      RRID:AB_627268

      DOI: 10.3390/cancers11101456

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    mdpi.com/2072-6694/11/10/1456
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    LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion
    1
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      DOI: 10.1016/j.celrep.2019.11.063

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    sciencedirect.com/science/article/pii/S2211124719315542
  13. www.embopress.org www.embopress.org
    Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2
    1
    1. scibot 13 Jan 2020
      RRID:AB_627268

      DOI: 10.15252/embr.201947845

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    embopress.org/doi/full/10.15252/embr.201947845
  14. www.sciencedirect.com www.sciencedirect.com
    Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein
    1
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      DOI: 10.1016/j.celrep.2019.11.116

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    sciencedirect.com/science/article/pii/S2211124719316390
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    A Consensus Binding Motif for the PP4 Protein Phosphatase
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.08.029

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    sciencedirect.com/science/article/pii/S1097276519306847
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pericentrin-mediated SAS-6 recruitment promotes centriole assembly
    1
    1. scibot 13 Jan 2020
      RRID:AB_627268

      DOI: 10.7554/eLife.41418

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    ncbi.nlm.nih.gov/pmc/articles/PMC6559791/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis
    1
    1. scibot 13 Jan 2020
      RRID:AB_627268

      DOI: 10.7554/eLife.50850

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    ncbi.nlm.nih.gov/pmc/articles/PMC6927744/
  18. www.sciencedirect.com www.sciencedirect.com
    Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.cell.2019.12.004

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    sciencedirect.com/science/article/pii/S0092867419313303
  19. www.sciencedirect.com www.sciencedirect.com
    Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors
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      DOI: 10.1016/j.chembiol.2017.11.007

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    sciencedirect.com/science/article/pii/S2451945617304245
  20. www.sciencedirect.com www.sciencedirect.com
    Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS
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      DOI: 10.1016/j.cell.2019.05.003

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    sciencedirect.com/science/article/pii/S009286741930501X
  21. www.sciencedirect.com www.sciencedirect.com
    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
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      DOI: 10.1016/j.ccell.2019.10.002

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    sciencedirect.com/science/article/pii/S1535610819304763
  22. www.sciencedirect.com www.sciencedirect.com
    STRIPAK Members Orchestrate Hippo and Insulin Receptor Signaling to Promote Neural Stem Cell Reactivation
    1
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      RRID:AB_627268

      DOI: 10.1016/j.celrep.2019.05.023

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    sciencedirect.com/science/article/pii/S2211124719306345
  23. www.jneurosci.org www.jneurosci.org
    PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux
    1
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      RRID:AB_627268

      DOI: 10.1523/JNEUROSCI.2942-18.2019

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    jneurosci.org/content/39/27/5404
  24. www.sciencedirect.com www.sciencedirect.com
    Miro1 Marks Parkinson’s Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson’s Models
    1
    1. scibot 13 Jan 2020
      RRID:AB_627268

      DOI: 10.1016/j.cmet.2019.08.023

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    sciencedirect.com/science/article/pii/S1550413119304978
  25. www.sciencedirect.com www.sciencedirect.com
    Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis
    1
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      DOI: 10.1016/j.devcel.2019.08.006

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    sciencedirect.com/science/article/pii/S1534580719306665
  26. elifesciences.org elifesciences.org
    The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest
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      DOI: 10.7554/eLife.47566

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    elifesciences.org/articles/47566
  27. www.sciencedirect.com www.sciencedirect.com
    Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5
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      DOI: 10.1016/j.celrep.2019.08.102

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    sciencedirect.com/science/article/pii/S2211124719311647
  28. www.sciencedirect.com www.sciencedirect.com
    The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy
    1
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      DOI: 10.1016/j.brainres.2019.146569

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    sciencedirect.com/science/article/pii/S0006899319306237
  29. www.sciencedirect.com www.sciencedirect.com
    Nuclear Pre-snRNA Export Is an Essential Quality Assurance Mechanism for Functional Spliceosomes
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      DOI: 10.1016/j.celrep.2019.05.031

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    sciencedirect.com/science/article/pii/S2211124719306515
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.7554/eLife.41301

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    ncbi.nlm.nih.gov/pmc/articles/PMC6294550/
  31. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.04.017

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    sciencedirect.com/science/article/pii/S2211124719304826
  32. www.sciencedirect.com www.sciencedirect.com
    Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain
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      DOI: 10.1016/j.celrep.2018.12.077

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    sciencedirect.com/science/article/pii/S2211124718320229
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      DOI: 10.1016/j.molcel.2019.04.026

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    sciencedirect.com/science/article/pii/S1097276519303181
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    sciencedirect.com/science/article/pii/S1097276518309882
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    sciencedirect.com/science/article/pii/S0024320519302796
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1111/ejn.14311

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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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      DOI: 10.1016/j.ccell.2019.01.006

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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
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      DOI: 10.1016/j.cell.2019.03.006

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    sciencedirect.com/science/article/pii/S0092867419302685
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      DOI: 10.1016/j.neuron.2019.04.003

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    sciencedirect.com/science/article/pii/S0896627319303381
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    sciencedirect.com/science/article/pii/S2451945619301084
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    sciencedirect.com/science/article/pii/S0969212619300115
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    Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control
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    Recognition and ER Quality Control of Misfolded Formylglycine-Generating Enzyme by Protein Disulfide Isomerase
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    UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F
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    The InR/Akt/TORC1 Growth-Promoting Signaling Negatively Regulates JAK/STAT Activity and Migratory Cell Fate during Morphogenesis
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    PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions
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    Cell Identity Switching Regulated by Retinoic Acid Signaling Maintains Homogeneous Segments in the Hindbrain
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    Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding
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    A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome
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    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
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  88. www.sciencedirect.com www.sciencedirect.com
    JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex
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  89. academic.oup.com academic.oup.com
    Combined Hyperglycemia- and Hyperinsulinemia-Induced Insulin Resistance in Adipocytes Is Associated With Dual Signaling Defects Mediated by PKC-ζ
    1
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  90. www.sciencedirect.com www.sciencedirect.com
    Clptm1 Limits Forward Trafficking of GABAA Receptors to Scale Inhibitory Synaptic Strength
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  91. www.sciencedirect.com www.sciencedirect.com
    The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30
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  92. www.sciencedirect.com www.sciencedirect.com
    Mechanisms Connecting the Conserved Protein Kinases Ssp1, Kin1, and Pom1 in Fission Yeast Cell Polarity and Division
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  93. www.sciencedirect.com www.sciencedirect.com
    Structural Insights into Yeast Telomerase Recruitment to Telomeres
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  94. europepmc.org europepmc.org
    Untitled document
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  95. europepmc.org europepmc.org
    MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma
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  96. europepmc.org europepmc.org
    An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis.
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  97. www.sciencedirect.com www.sciencedirect.com
    NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis
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    sciencedirect.com/science/article/pii/S1097276517307931
  98. Nov 2017
  99. www.jci.org www.jci.org
    Mutations in the netrin-1 gene cause congenital mirror movements
    1
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      Curator: @patriciaelyse_

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  100. www.sciencedirect.com www.sciencedirect.com
    Phospho-Regulation of Soma-to-Axon Transcytosis of Neurotrophin Receptors
    1
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    sciencedirect.com/science/article/pii/S1534580717306603
  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid‐β oligomers
    1
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14118/full
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin
    1
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  103. elifesciences.org elifesciences.org
    Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division
    1
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    elifesciences.org/articles/25014
  104. www.sciencedirect.com www.sciencedirect.com
    A Tunable Brake for HECT Ubiquitin Ligases
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  105. www.sciencedirect.com www.sciencedirect.com
    PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response
    1
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  106. elifesciences.org elifesciences.org
    The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling
    2
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    elifesciences.org/articles/26362
  107. www.sciencedirect.com www.sciencedirect.com
    RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination
    1
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  108. www.sciencedirect.com www.sciencedirect.com
    A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability
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  109. www.sciencedirect.com www.sciencedirect.com
    The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated Degradation
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  110. www.jbc.org www.jbc.org
    Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND “OFF-PATHWAY” CELLULAR MECHANISMS
    1
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      Anti-c-Myc mouse 9E10

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  111. elifesciences.org elifesciences.org
    p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway
    1
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      AB_627268

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    elifesciences.org/content/6/e22207
  112. elifesciences.org elifesciences.org
    YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB
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  113. www.sciencedirect.com www.sciencedirect.com
    Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy
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      AB_627268

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  114. elifesciences.org elifesciences.org
    Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain
    1
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    elifesciences.org/articles/23024
  115. www.sciencedirect.com www.sciencedirect.com
    Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17
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  116. www.jneurosci.org www.jneurosci.org
    KCTD Hetero-oligomers Confer Unique Kinetic Properties on Hippocampal GABAB Receptor-Induced K+ Currents
    1
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      AB_627268

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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy
    1
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of mTORC1 by lysosomal calcium and calmodulin
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    ncbi.nlm.nih.gov/pmc/articles/PMC5106211/
  119. www.sciencedirect.com www.sciencedirect.com
    Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread
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  120. www.nature.com www.nature.com
    Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer|[rsquo]|s disease
    1
    1. scibot 08 Nov 2017
      anti-myc

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    nature.com/mp/journal/vaop/ncurrent/full/mp2015181a.html
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ Signaling Regulates the Timing of CNS Myelination by Modulating Oligodendrocyte Progenitor Cell Cycle Exit through SMAD3/4/FoxO1/Sp1
    1
    1. scibot 08 Nov 2017
      AB_627268

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC4044250
  122. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function
    1
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    onlinelibrary.wiley.com/doi/10.1111/jnc.13038/full