247 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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    1. scibot 14 May 2024
      CVCL_0480

      DOI: 10.1016/j.celrep.2024.114202

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    sciencedirect.com/science/article/pii/S2211124724005308
  3. May 2024
  4. 52.53.155.43 52.53.155.43
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
    2
    1. scibot 10 May 2024
      RRID:CVCL_0480

      DOI: 10.1101/2024.02.18.580900

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    2. scibot 10 May 2024
      RRID:CVCL_0480

      DOI: 10.1101/2024.02.18.580900

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    52.53.155.43/97841ca504d9556b3965877911b65905cd7f6735/2024.02.18.580900v1.full-html.html
  5. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin-mediated regulation of APE2 protein abundance
    1
    1. scibot 07 May 2024
      CRL-1469

      DOI: 10.1016/j.jbc.2024.107337

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    sciencedirect.com/science/article/pii/S0021925824018386
  6. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Disrupting the interaction between a p53 gain-of-function mutant and the transcriptional co-activator PC4 reverses drug resistance in cancer cells
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    1. scibot 02 May 2024
      RRID:CVCL_0480

      DOI: 10.1002/1873-3468.14890

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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14890
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    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer
    1
    1. scibot 01 May 2024
      CRL-1469

      DOI: 10.1016/j.celrep.2024.114176

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    sciencedirect.com/science/article/pii/S2211124724005047
  8. Apr 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BUB1 Promotes Gemcitabine Resistance in Pancreatic Cancer Cells by Inhibiting Ferroptosis
    1
    1. scibot 30 Apr 2024
      RRID:CVCL_0480

      DOI: 10.3390/cancers16081540

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    ncbi.nlm.nih.gov/pmc/articles/PMC11048608/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
    1
    1. scibot 27 Apr 2024
      RRID:CVCL_0480

      DOI: 10.1186/s12935-024-03339-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11044319/
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    Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases
    1
    1. scibot 26 Apr 2024
      CVCL_0480

      DOI: 10.1016/j.xcrm.2024.101523

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    sciencedirect.com/science/article/pii/S2666379124001927
  12. link.springer.com link.springer.com
    Heterodimerization of T cell engaging bispecific antibodies to enhance specificity against pancreatic ductal adenocarcinoma
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    1. scibot 24 Apr 2024
      RRID:CVCL_0480

      DOI: 10.1186/s13045-024-01538-5

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    link.springer.com/article/10.1186/s13045-024-01538-5
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    QDPR deficiency drives immune suppression in pancreatic cancer
    1
    1. scibot 23 Apr 2024
      RRID:CVCL_0480

      DOI: 10.1016/j.cmet.2024.03.015

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    sciencedirect.com/science/article/pii/S1550413124001190
  14. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin ligase TRIM15 promotes the progression of pancreatic cancer via the upregulation of the IGF2BP2-TLR4 axis
    1
    1. scibot 23 Apr 2024
      RRID:CVCL_0480

      DOI: 10.1016/j.bbadis.2024.167183

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    sciencedirect.com/science/article/pii/S0925443924001728
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
    1
    1. scibot 18 Apr 2024
      RRID:CVCL_0480

      DOI: 10.1002/ijc.34960

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34960
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration
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    1. scibot 05 Apr 2024
      RRID:CVCL_0480

      DOI: 10.1002/1878-0261.13609

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13609
  17. www.sciencedirect.com www.sciencedirect.com
    The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells
    1
    1. scibot 04 Apr 2024
      RRID:CVCL_0480

      DOI: 10.1016/j.devcel.2024.03.018

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    sciencedirect.com/science/article/pii/S1534580724001837
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Non-Viral DNA Delivery System Consisting of Multifunctional Chimaeric Peptide Fused with Zinc Finger Protein
    1
    1. scibot 03 Apr 2024
      CVCL_0480

      DOI: 10.1016/j.isci.2024.109464

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    ncbi.nlm.nih.gov/pmc/articles/PMC10981093/
  19. Mar 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    1. scibot 29 Mar 2024
      Cat#CRL-1469

      DOI: 10.1016/j.chembiol.2024.02.013

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    sciencedirect.com/science/article/pii/S2451945624000874
  21. www.sciencedirect.com www.sciencedirect.com
    Hyperthermia improves gemcitabine sensitivity of pancreatic cancer cells by suppressing the EFNA4/β-catenin axis and activating dCK
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    1. scibot 29 Mar 2024
      RRID:CVCL_0480

      DOI: 10.1016/j.heliyon.2024.e28488

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    sciencedirect.com/science/article/pii/S2405844024045195
  22. dx.doi.org dx.doi.org
    LMO3 is a suppressor of the basal-like/squamous subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism
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    1. scibot 22 Mar 2024
      RRID:CVCL_0480

      DOI: 10.1093/carcin/bgae011

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    dx.doi.org/10.1093/carcin/bgae011
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer
    1
    1. scibot 12 Mar 2024
      RRID:CVCL_0480

      DOI: 10.1038/s41420-024-01890-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10924943/
  24. www.sciencedirect.com www.sciencedirect.com
    PRMT1 promotes pancreatic cancer development and resistance to chemotherapy
    2
    1. scibot 12 Mar 2024
      CVCL_0480

      DOI: 10.1016/j.xcrm.2024.101461

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    2. scibot 12 Mar 2024
      CVCL_0480

      DOI: 10.1016/j.xcrm.2024.101461

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    sciencedirect.com/science/article/pii/S2666379124001058
  25. Feb 2024
  26. 52.53.155.43 52.53.155.43
    176-html.html
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    1. scibot 27 Feb 2024
      RRID: CVCL_0480

      DOI: 10.1158/2159-8290.cd-23-0334

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    52.53.155.43/2ec0d88e67b798a89b6c5516dbe547b3b2c5ce80/176-html.html
  27. aacrjournals.org aacrjournals.org
    Mitochondrial translocase TOMM22 is overexpressed in pancreatic cancer and promotes aggressive growth by modulating mitochondrial protein import and function
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    1. scibot 24 Feb 2024
      RRID:CVCL_0480

      DOI: 10.1158/1541-7786.MCR-23-0138

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    aacrjournals.org/mcr/article/22/2/197/733695/Mitochondrial-Translocase-TOMM22-Is-Overexpressed
  28. aacrjournals.org aacrjournals.org
    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
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    1. scibot 23 Feb 2024
      RRID:CVCL_0480

      DOI: 10.1158/1078-0432.CCR-23-1143

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      RRID:CVCL_0480

      DOI: 10.1158/1078-0432.CCR-23-1143

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    aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
  29. 52.53.155.43 52.53.155.43
    An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth
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    1. scibot 22 Feb 2024
      RRID:CVCL_0480

      DOI: 10.1101/2023.08.23.554263

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  30. 52.53.155.43 52.53.155.43
    Identification of FOXP3+ epithelial cells contributing to pancreatic proliferation and angiogenesis
    1
    1. scibot 22 Feb 2024
      RRID:CVCL_0480

      DOI: 10.1152/ajpcell.00461.2023

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    52.53.155.43/a4875dd9547eaa8b044abee79367d9ba9aa4f8c4/gong-et-al-2024-identification-of-foxp3-epithelial-cells-contributing-to-pancreatic-proliferation-and-angiogenesis-html.html
  31. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    1. scibot 22 Feb 2024
      RRID:CVCL_0480

      DOI: 10.1016/j.xcrm.2024.101434

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    sciencedirect.com/science/article/pii/S2666379124000570
  32. www.sciencedirect.com www.sciencedirect.com
    Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells
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    1. scibot 22 Feb 2024
      RRID:CVCL_0480

      DOI: 10.1016/j.phymed.2024.155392

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    sciencedirect.com/science/article/pii/S0944711324000576
  33. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Feb 2024
      RRID:CVCL_0480

      DOI: 10.1111/bph.16289

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16289
  34. journals.physiology.org journals.physiology.org
    Identification of FOXP3+ epithelial cells contributing to pancreatic proliferation and angiogenesis
    1
    1. scibot 16 Feb 2024
      RRID:CVCL_0480

      DOI: 10.1152/ajpcell.00461.2023

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    journals.physiology.org/doi/10.1152/ajpcell.00461.2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
    1
    1. scibot 09 Feb 2024
      RRID:CVCL_0480

      DOI: 10.1172/JCI173299

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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
  36. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
    1
    1. scibot 08 Feb 2024
      ATCCCat# CRL-1469

      DOI: 10.1016/j.molcel.2024.01.012

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    sciencedirect.com/science/article/pii/S1097276524000480
  37. www.sciencedirect.com www.sciencedirect.com
    Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy
    1
    1. scibot 08 Feb 2024
      ATCC, CRL-1469

      DOI: 10.1016/j.canlet.2024.216696

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    sciencedirect.com/science/article/abs/pii/S0304383524000892
  38. Jan 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress
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    1. scibot 25 Jan 2024
      PRID : CVCL_0480

      DOI: 10.3389/fonc.2023.1196546

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      Curator: @anisehay

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    ncbi.nlm.nih.gov/pmc/articles/PMC10391547/
  40. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet
    1
    1. scibot 25 Jan 2024
      RRID: CVCL_0480

      DOI: 10.1111/febs.17058

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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17058
  41. link.springer.com link.springer.com
    Machine Learning Developed a MYC Expression Feature-Based Signature for Predicting Prognosis and Chemoresistance in Pancreatic Adenocarcinoma
    1
    1. scibot 25 Jan 2024
      RRID:CVCL_0480

      DOI: 10.1007/s10528-023-10625-0

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    link.springer.com/article/10.1007/s10528-023-10625-0
  42. www.mdpi.com www.mdpi.com
    Multi-Algorithm Analysis Reveals Pyroptosis-Linked Genes as Pancreatic Cancer Biomarkers
    1
    1. scibot 21 Jan 2024
      RRID:CVCL_0480

      DOI: 10.3390/cancers16020372

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    mdpi.com/2072-6694/16/2/372
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma
    1
    1. scibot 20 Jan 2024
      RRID: CVCL_0480

      DOI: 10.1158/0008-5472.CAN-23-1148

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC10790128/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elaiophylin Elicits Robust Anti-Tumor Responses via Apoptosis Induction and Attenuation of Proliferation, Migration, Invasion, and Angiogenesis in Pancreatic Cancer Cells
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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic analysis reveals HDAC1 regulates clinically relevant transcriptional programs in Pancreatic cancer
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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of the KRAS-NRF2 axis shifts arginine into the phosphocreatine energy system in pancreatic cancer cells
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      CVCL_0480

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  47. www.sciencedirect.com www.sciencedirect.com
    KH-like domains in PARP9/DTX3L and PARP14 coordinate protein-protein interactions to promote cancer cell survival
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      DOI: 10.1016/j.jmb.2023.168434

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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer
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  49. Dec 2023
  50. www.sciencedirect.com www.sciencedirect.com
    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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      DOI: 10.1016/j.xcrm.2023.101326

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  51. link.springer.com link.springer.com
    Revealing the tumor suppressive sequence within KL1 domain of the hormone Klotho
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  52. 52.53.155.43 52.53.155.43
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  53. Nov 2023
  54. www.sciencedirect.com www.sciencedirect.com
    SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
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  55. www.mdpi.com www.mdpi.com
    IK Channel-Independent Effects of Clotrimazole and Senicapoc on Cancer Cells Viability and Migration
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      DOI: 10.3390/ijms242216285

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  56. www.biorxiv.org www.biorxiv.org
    LMO3 is a suppressor of the basal-like/squamous PDAC subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism
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      DOI: 10.1101/2023.11.01.564448

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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Trapping all ERBB ligands decreases pancreatic lesions in a murine model of pancreatic ductal adenocarcinoma
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  58. www.embopress.org www.embopress.org
    MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression
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      DOI: 10.15252/embj.2023114558

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  59. Oct 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Synergistic antitumor efficacy of rMV-Hu191 and Olaparib in pancreatic cancer by generating oxidative DNA damage and ROS-dependent apoptosis
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      DOI: 10.1016/j.tranon.2023.101812

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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen-specific tumor cell killing by cytotoxic T cells
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      CRL-1469

      DOI: 10.7554/eLife.84314

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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer
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      DOI: 10.1158/2767-9764.CRC-22-0521

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  63. Sep 2023
  64. www.biorxiv.org www.biorxiv.org
    ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
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      DOI: 10.1101/2023.09.23.558894

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  65. link.springer.com link.springer.com
    Heteronemin promotes iron-dependent cell death in pancreatic cancer
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      DOI: 10.1007/s00210-023-02736-7

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  66. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma
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      DOI: 10.1016/j.canlet.2023.216411

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  67. www.sciencedirect.com www.sciencedirect.com
    Natural killer cell therapy targeting cancer stem cells: Old wine in a new bottle
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      DOI: 10.1016/j.canlet.2023.216328

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  68. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Horie-html.html
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      DOI: 10.1002/1878-0261.13524

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  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Removal of gemcitabine-induced senescent cancer cells by targeting glutaminase1 improves the therapeutic effect in pancreatic ductal adenocarcinoma
    1
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  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Collagen XVII regulates tumor growth in pancreatic cancer through interaction with the tumor microenvironment
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  71. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Kleszcz-html.html
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      DOI: 10.1111/bph.16224

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  72. Aug 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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      CVCL_0480

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  74. www.sciencedirect.com www.sciencedirect.com
    Synthesis of fluorinated triphenylphosphonium analogs that improve cancer cell selectivity and in vivo detection
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      DOI: 10.1016/j.xpro.2023.102437

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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
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      DOI: 10.1016/j.isci.2023.107408

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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Palbociclib suppresses the cancer stem cell properties and cell proliferation through increased levels of miR-506 or miR-150 in Panc-1 and MiaPaCa-2 cells
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      CVCL_0480

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  77. Jul 2023
  78. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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      DOI: 10.1016/j.cell.2023.06.020

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SALL4‐related gene signature defines a specific stromal subset of pancreatic ductal adenocarcinoma with poor prognostic features
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      DOI: 10.1002/1878-0261.13370

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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The MyD88 inhibitor, ST2825, induces cell cycle arrest and apoptosis by suppressing the activation of the NF‑κB/AKT1/p21 pathway in pancreatic cancer
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      RRID:CVCL_0480

      DOI: 10.3892/or.2023.8585

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  81. Jun 2023
  82. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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      DOI: 10.1038/s41467-023-39241-7

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  83. www.biorxiv.org www.biorxiv.org
    Reliable, standardized measurements for cell mechanical properties
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      DOI: 10.1101/2023.06.14.544753

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  84. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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      DOI: 10.1158/0008-5472.CAN-22-2045

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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  85. www.sciencedirect.com www.sciencedirect.com
    Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma
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      DOI: 10.1016/j.celrep.2023.112581

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  86. May 2023
  87. www.nature.com www.nature.com
    Roundabout homolog 1 inhibits proliferation via the YY1-ROBO1-CCNA2-CDK2 axis in human pancreatic cancer
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      RRID: CVCL-0480

      DOI: 10.1038/s41388-021-01741-5

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  88. www.sciencedirect.com www.sciencedirect.com
    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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      DOI: 10.1016/j.ccell.2023.04.018

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  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity
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      DOI: 10.1002/ijc.34528

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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
    1
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      RRID:CVCL_0480

      DOI: 10.1158/0008-5472.CAN-22-3000

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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  91. www.sciencedirect.com www.sciencedirect.com
    Pharmacological ascorbate induces sustained mitochondrial dysfunction
    1
    1. scibot 03 May 2023
      RRID: CVCL_0480

      DOI: 10.1016/j.freeradbiomed.2023.04.023

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    sciencedirect.com/science/article/pii/S0891584923004008
  92. www.sciencedirect.com www.sciencedirect.com
    IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization
    1
    1. scibot 03 May 2023
      RRID:CVCL_0480

      DOI: 10.1016/j.chembiol.2023.04.005

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    sciencedirect.com/science/article/pii/S2451945623000910
  93. Apr 2023
  94. link.springer.com link.springer.com
    Activation of Vitamin D/VDR Signaling Reverses Gemcitabine Resistance of Pancreatic Cancer Cells Through Inhibition of MUC1 Expression
    1
    1. scibot 20 Apr 2023
      RRID:CVCL_0480

      DOI: 10.1007/s10620-023-07931-3

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    link.springer.com/article/10.1007/s10620-023-07931-3
  95. www.biorxiv.org www.biorxiv.org
    A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer
    2
    1. scibot 07 Apr 2023
      CVCL_0480

      DOI: 10.1101/2023.02.15.528599

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    2. scibot 07 Apr 2023
      CVCL_0480

      DOI: 10.1101/2023.02.15.528599

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    biorxiv.org/content/10.1101/2023.02.15.528599v1
  96. Mar 2023
  97. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tissue-resident CXCR4+ macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression
    1
    1. scibot 18 Mar 2023
      RRID:CVCL_0480

      DOI: 10.1002/ijc.34468

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34468
  98. www.nature.com www.nature.com
    Non-canonical functions of SNAIL drive context-specific cancer progression
    1
    1. scibot 09 Mar 2023
      CVCL_0480

      DOI: 10.1038/s41467-023-36505-0

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    nature.com/articles/s41467-023-36505-0
  99. Jan 2023
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
    1
    1. scibot 12 Jan 2023
      CVCL_0480

      DOI: 10.1158/1535-7163.MCT-21-0518

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    ncbi.nlm.nih.gov/pmc/articles/PMC9377749/
  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chronic acidosis rewires cancer cell metabolism through PPARα signaling
    1
    1. scibot 10 Jan 2023
      RRID:CVCL_0480

      DOI: 10.1002/ijc.34404

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34404
  102. www.nature.com www.nature.com
    NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
    1
    1. scibot 04 Jan 2023
      RRID:CVCL_0480

      DOI: 10.1038/s41419-022-05535-9

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    nature.com/articles/s41419-022-05535-9
  103. Dec 2022
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    JNK inhibitor IX restrains pancreatic cancer through p53 and p21
    1
    1. scibot 31 Dec 2022
      CVCL_0480

      DOI: 10.3389/fonc.2022.1006131

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    ncbi.nlm.nih.gov/pmc/articles/PMC9768178/
  105. www.cell.com www.cell.com
    Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin
    1
    1. scibot 22 Dec 2022
      RRID:CVCL_0480

      DOI: 10.1016/j.isci.2022.105670

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    cell.com/iscience/abstract/S2589-0042(22)01942-3
  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Crosstalk between tumor acidosis, p53, and extracellular matrix regulates pancreatic cancer aggressiveness
    1
    1. scibot 22 Dec 2022
      RRID:CVCL_0480

      DOI: 10.1002/ijc.34367

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34367
  107. www.sciencedirect.com www.sciencedirect.com
    The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response
    1
    1. scibot 18 Dec 2022
      RRID:CVCL_0480

      DOI: 10.1016/j.celrep.2022.111819

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    sciencedirect.com/science/article/pii/S2211124722017119
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Cell Derived Exosomal GOT1 Suppresses Tumor Cell Ferroptosis to Accelerate Pancreatic Cancer Progression by Activating Nrf2/HO-1 Axis via Upregulating CCR2 Expression
    1
    1. scibot 13 Dec 2022
      RRID:CVCL_0480

      DOI: 10.3390/cells11233893

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    ncbi.nlm.nih.gov/pmc/articles/PMC9735520/
  109. Nov 2022
  110. aacrjournals.org aacrjournals.org
    LncRNA A2M-AS1 promotes ferroptosis in pancreatic cancer via interacting with PCBP3
    1
    1. scibot 22 Nov 2022
      RRID:CVCL_0480

      DOI: 10.1158/1541-7786.MCR-22-0024

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    aacrjournals.org/mcr/article/20/11/1636/709851/LncRNA-A2M-AS1-Promotes-Ferroptosis-in-Pancreatic
  111. www.sciencedirect.com www.sciencedirect.com
    Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer
    1
    1. scibot 16 Nov 2022
      RRID:CVCL_0480

      DOI: 10.1016/j.xcrm.2022.100815

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    sciencedirect.com/science/article/pii/S2666379122003743
  112. www.sciencedirect.com www.sciencedirect.com
    NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma
    1
    1. scibot 09 Nov 2022
      CRL-1469

      DOI: 10.1016/j.celrep.2022.111623

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2211124722014942
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophils in pancreatic cancer: Potential therapeutic targets
    1
    1. scibot 04 Nov 2022
      RRID: CVCL_0480

      DOI: 10.3389/fonc.2022.1025805

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    ncbi.nlm.nih.gov/pmc/articles/PMC9618950/
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NetrinG1+ cancer-associated fibroblasts generate unique extracellular vesicles that support the survival of pancreatic cancer cells under nutritional stress
    1
    1. scibot 02 Nov 2022
      RRID:CVCL_0480

      DOI: 10.1158/2767-9764.crc-21-0147

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    ncbi.nlm.nih.gov/pmc/articles/PMC9608356/
  115. Oct 2022
  116. 52.53.155.43 52.53.155.43
    mcr-22-0024-html.html
    1
    1. scibot 28 Oct 2022
      RRID:CVCL_0480

      DOI: 10.1158/1541-7786.mcr-22-0024

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    52.53.155.43/152bcbe47b15eed8dfa22d3b4b0931d8168d4dde/mcr-22-0024-html.html
  117. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Serum levels of iCAF-derived Osteoglycin predict favorable outcome in pancreatic cancer
    1
    1. scibot 27 Oct 2022
      RRID:CVCL_0480

      DOI: 10.1002/ijc.34276

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34276
  118. aacrjournals.org aacrjournals.org
    Selenium modulates cancer cell response to pharmacologic ascorbate
    1
    1. scibot 27 Oct 2022
      RRID:CVCL_0480

      DOI: 10.1158/0008-5472.CAN-22-0408

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    aacrjournals.org/cancerres/article/82/19/3486/709413/Selenium-Modulates-Cancer-Cell-Response-to
  119. link.springer.com link.springer.com
    Proteome alterations during clonal isolation of established human pancreatic cancer cell lines
    1
    1. scibot 25 Oct 2022
      RRID:CVCL_0480

      DOI: 10.1007/s00018-022-04584-9

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    link.springer.com/article/10.1007/s00018-022-04584-9
  120. Sep 2022
  121. www.sciencedirect.com www.sciencedirect.com
    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
    1
    1. scibot 29 Sep 2022
      RRID:CVCL_0480

      DOI: 10.1016/j.celrep.2022.111428

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    sciencedirect.com/science/article/pii/S2211124722012694
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
    1
    1. scibot 22 Sep 2022
      CVCL_0480

      DOI: 10.1136/gutjnl-2021-324994

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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EMT-induced gemcitabine resistance in pancreatic cancer involves the functional loss of equilibrative nucleoside transporter 1
    1
    1. scibot 21 Sep 2022
      RRID:CVCL_0480

      DOI: 10.1158/1535-7163.MCT-20-0316

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    ncbi.nlm.nih.gov/pmc/articles/PMC9464091/
  124. www.nature.com www.nature.com
    A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing
    1
    1. scibot 07 Sep 2022
      RRID:CVCL_0480

      DOI: 10.1038/s41557-022-01021-z

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    nature.com/articles/s41557-022-01021-z
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decellularization of xenografted tumors provides cell-specific in vitro 3D environment
    1
    1. scibot 03 Sep 2022
      CVCL_0480

      DOI: 10.3389/fonc.2022.956940

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    ncbi.nlm.nih.gov/pmc/articles/PMC9434107/
  126. Aug 2022
  127. insight.jci.org insight.jci.org
    Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer
    1
    1. scibot 27 Aug 2022
      RRID:CVCL_0480

      DOI: 10.1172/jci.insight.154475

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    insight.jci.org/articles/view/154475
  128. www.sciencedirect.com www.sciencedirect.com
    Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
    1
    1. scibot 27 Aug 2022
      ATCCCat#CRL-1469

      DOI: 10.1016/j.ccell.2022.08.001

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1535610822003579
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent inhibition of IGF1R and ERK increases pancreatic cancer sensitivity to autophagy inhibitors
    1
    1. scibot 22 Aug 2022
      RRID:CVCL_0480

      DOI: 10.1158/0008-5472.CAN-21-1443

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    ncbi.nlm.nih.gov/pmc/articles/PMC8886214/
  130. link.springer.com link.springer.com
    CDK7 inhibition augments response to multidrug chemotherapy in pancreatic cancer
    1
    1. scibot 11 Aug 2022
      RRID:CVCL_0480

      DOI: 10.1186/s13046-022-02443-w

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  131. Jul 2022
  132. www.sciencedirect.com www.sciencedirect.com
    Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness
    1
    1. scibot 27 Jul 2022
      RRID:CVCL_0480

      DOI: 10.1016/j.isci.2022.104721

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    sciencedirect.com/science/article/pii/S2589004222009932
  133. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploring the potential of exosomes in diagnosis and drug delivery for PDAC
    1
    1. scibot 15 Jul 2022
      RRID:CVCL_0480

      DOI: 10.1002/ijc.34195

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34195
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
    1
    1. scibot 12 Jul 2022
      RRID:CVCL_0480

      DOI: 10.3390/cancers14133152

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    ncbi.nlm.nih.gov/pmc/articles/PMC9264918/
  135. link.springer.com link.springer.com
    Lipocalin-2 inhibits pancreatic cancer stemness via the AKT/c-Jun pathway
    1
    1. scibot 07 Jul 2022
      RRID:CVCL_0480

      DOI: 10.1007/s13577-022-00735-z

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    link.springer.com/article/10.1007/s13577-022-00735-z
  136. Jun 2022
  137. www.sciencedirect.com www.sciencedirect.com
    GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma
    1
    1. scibot 09 Jun 2022
      RRID:CVCL_0480

      DOI: 10.1016/j.pan.2022.06.006

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1424390322001983
  138. May 2022
  139. www.researchsquare.com www.researchsquare.com
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    1. scibot 20 May 2022
      RRID:CVCL_0480

      DOI: 10.21203/rs.3.rs-658360/v1

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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress
    1
    1. scibot 11 May 2022
      RRID:CVCL_0480

      DOI: 10.7554/eLife.69255

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    ncbi.nlm.nih.gov/pmc/articles/PMC9064299/
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silencing of Carboxypeptidase E expression inhibits proliferation and invasion of Panc-1 pancreatic cancer cells
    1
    1. scibot 11 May 2022
      RRID:CVCL_0480

      DOI: 10.12688/f1000research.53737.2

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    ncbi.nlm.nih.gov/pmc/articles/PMC9069412/
  142. Apr 2022
  143. link.springer.com link.springer.com
    ATX/LPA axis regulates FAK activation, cell proliferation, apoptosis, and motility in human pancreatic cancer cells
    1
    1. scibot 16 Apr 2022
      RRID:CVCL_0480

      DOI: 10.1007/s11626-022-00660-3

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    link.springer.com/article/10.1007/s11626-022-00660-3
  144. www.sciencedirect.com www.sciencedirect.com
    EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer
    1
    1. scibot 15 Apr 2022
      ATCCCat# CRL-1469

      DOI: 10.1016/j.isci.2022.104193

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2589004222004631
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UHMK1 Is a Novel Marker for Personalized Prediction of Pancreatic Cancer Prognosis
    1
    1. scibot 01 Apr 2022
      CVCL_0480

      DOI: 10.3389/fonc.2022.834647

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    ncbi.nlm.nih.gov/pmc/articles/PMC8960145/
  146. Mar 2022
  147. www.embopress.org www.embopress.org
    Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression
    1
    1. scibot 22 Mar 2022
      RRID:CVCL_0480

      DOI: 10.15252/embj.2021110466

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    embopress.org/doi/abs/10.15252/embj.2021110466
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist
    1
    1. scibot 11 Mar 2022
      RRID:CVCL_0480

      DOI: 10.1038/s41598-022-07600-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC8901637/
  149. www.sciencedirect.com www.sciencedirect.com
    Chemically and mechanically defined hyaluronan hydrogels emulate the extracellular matrix for unbiased in vivo and in vitro organoid formation and drug testing in cancer
    1
    1. scibot 04 Mar 2022
      ATCC® CRL-1469

      DOI: 10.1016/j.mattod.2022.01.023

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    sciencedirect.com/science/article/pii/S1369702122000232
  150. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 03 Mar 2022
      RRID:CVCL_0480

      DOI: 10.1111/bph.15810

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15810
  151. Feb 2022
  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma
    1
    1. scibot 16 Feb 2022
      RRID:CVCL_0480

      DOI: 10.1158/0008-5472.CAN-21-1677

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    ncbi.nlm.nih.gov/pmc/articles/PMC7611539/
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A community challenge for a pancancer drug mechanism of action inference from perturbational profile data
    1
    1. scibot 02 Feb 2022
      RRID:CVCL_0480

      DOI: 10.1016/j.xcrm.2021.100492

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    ncbi.nlm.nih.gov/pmc/articles/PMC8784774/
  154. link.springer.com link.springer.com
    Romidepsin and tamoxifen cooperatively induce senescence of pancreatic cancer cells through downregulation of FOXM1 expression and induction of reactive oxygen species/lipid peroxidation
    1
    1. scibot 01 Feb 2022
      RRID:CVCL_0480

      DOI: 10.1007/s11033-022-07192-9

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    link.springer.com/article/10.1007/s11033-022-07192-9
  155. Jan 2022
  156. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive Channel Piezo1 Induces Cell Apoptosis in Pancreatic Cancer by Ultrasound with Microbubbles
    1
    1. scibot 27 Jan 2022
      RRID:CVCL_0480

      DOI: 10.1016/j.isci.2022.103733

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    sciencedirect.com/science/article/pii/S2589004222000037
  157. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
    1
    1. scibot 16 Jan 2022
      RRID:CVCL_0480

      DOI: 10.1016/j.celrep.2021.110236

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    sciencedirect.com/science/article/pii/S2211124721017459
  158. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    1
    1. scibot 12 Jan 2022
      CRL-1469

      DOI: 10.1016/j.celrep.2021.110233

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    sciencedirect.com/science/article/pii/S2211124721017423
  159. journals.sagepub.com journals.sagepub.com
    Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021
    1
    1. scibot 12 Jan 2022
      CVCL_0480

      DOI: 10.1177/24725552211038362

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  160. journals.lww.com journals.lww.com
    Stearoyl-CoA desaturase 1 inhibitor supplemented with... : Journal of Pancreatology
    1
    1. scibot 12 Jan 2022
      RRID:CVCL_0480

      DOI: 10.1097/JP9.0000000000000082

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    journals.lww.com/jpancreatology/Fulltext/2021/12000/Stearoyl_CoA_desaturase_1_inhibitor_supplemented.5.aspx
  161. Dec 2021
  162. www.sciencedirect.com www.sciencedirect.com
    Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells
    1
    1. scibot 31 Dec 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.isci.2021.103653

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    sciencedirect.com/science/article/pii/S2589004221016230
  163. www.sciencedirect.com www.sciencedirect.com
    Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis
    1
    1. scibot 30 Dec 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.ebiom.2021.103797

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    sciencedirect.com/science/article/pii/S2352396421005910
  164. www.sciencedirect.com www.sciencedirect.com
    Protein modifications throughout the lung cancer proteome unravel the cancer-specific regulation of glycolysis
    1
    1. scibot 23 Dec 2021
      CRL-1469

      DOI: 10.1016/j.celrep.2021.110137

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    sciencedirect.com/science/article/pii/S2211124721016338
  165. journals.sagepub.com journals.sagepub.com
    Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021
    3
    1. scibot 23 Dec 2021
      CVCL_0480

      DOI: 10.1177/24725552211038362

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    2. scibot 15 Dec 2021
      CVCL_0480

      DOI: 10.1177/24725552211038362

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    3. scibot 04 Dec 2021
      CVCL_0480

      DOI: 10.1177/24725552211038362

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  166. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The enhancer rare germline variation rs548071605 contributes to lung cancer development
    1
    1. scibot 17 Dec 2021
      RRID:CVCL_0480

      DOI: 10.1002/humu.24310

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    onlinelibrary.wiley.com/doi/10.1002/humu.24310
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine deprivation triggers NAGK-dependent hexosamine salvage
    1
    1. scibot 04 Dec 2021
      RRID:CVCL_0480

      DOI: 10.7554/eLife.62644

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    ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
  168. www.nature.com www.nature.com
    Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
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    1. scibot 03 Dec 2021
      RRID:CVCL_0480

      DOI: 10.1038/s42003-021-02842-3

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    nature.com/articles/s42003-021-02842-3
  169. www.sciencedirect.com www.sciencedirect.com
    CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
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    1. scibot 01 Dec 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.celrep.2021.110060

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    sciencedirect.com/science/article/pii/S2211124721015461
  170. Nov 2021
  171. elifesciences.org elifesciences.org
    Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion
    1
    1. scibot 24 Nov 2021
      RRID:CVCL_0480

      DOI: 10.7554/eLife.66721

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    elifesciences.org/articles/66721
  172. www.sciencedirect.com www.sciencedirect.com
    A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
    1
    1. scibot 23 Nov 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.bioorg.2021.105505

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    sciencedirect.com/science/article/pii/S004520682100883X
  173. journals.sagepub.com journals.sagepub.com
    Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021
    2
    1. scibot 18 Nov 2021
      CVCL_0480

      DOI: 10.1177/24725552211038362

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      CVCL_0480

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  174. www.sciencedirect.com www.sciencedirect.com
    Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs
    1
    1. scibot 13 Nov 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.molcel.2021.10.018

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    sciencedirect.com/science/article/pii/S1097276521009102
  175. www.nature.com www.nature.com
    Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency
    1
    1. scibot 06 Nov 2021
      RRID:CVCL_0480

      DOI: 10.1038/s12276-021-00687-8

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    nature.com/articles/s12276-021-00687-8
  176. Oct 2021
  177. www.sciencedirect.com www.sciencedirect.com
    Marker-free lineage tracing reveals an environment-instructed clonogenic hierarchy in pancreatic cancer
    1
    1. scibot 21 Oct 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.celrep.2021.109852

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    sciencedirect.com/science/article/pii/S221112472101319X
  178. Sep 2021
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Light-Inducible Spatio-Temporal Control of TLR4 and NF-κB-Gluc Reporter in Human Pancreatic Cell Line
    1
    1. scibot 14 Sep 2021
      RRID:CVCL_0480

      DOI: 10.3390/ijms22179232

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    ncbi.nlm.nih.gov/pmc/articles/PMC8431472/
  180. Aug 2021
  181. link.springer.com link.springer.com
    YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models
    1
    1. scibot 31 Aug 2021
      RRID:CVCL_0480

      DOI: 10.1007/s13402-021-00630-z

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    link.springer.com/article/10.1007/s13402-021-00630-z
  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of Long Noncoding RNA AL161431.1 in the Development and Progression of Pancreatic Cancer
    1
    1. scibot 17 Aug 2021
      CVCL_0480

      DOI: 10.3389/fonc.2021.666313

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    ncbi.nlm.nih.gov/pmc/articles/PMC8363261/
  183. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Forward chemical genetic screen for oxygen-dependent cytotoxins uncovers new covalent fragments that target GPX4
    1
    1. scibot 16 Aug 2021
      RRID:CVCL_0480

      DOI: 10.1002/cbic.202100253

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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202100253
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
    1
    1. scibot 15 Aug 2021
      RRID:CVCL_0480

      DOI: 10.7554/eLife.59654

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    ncbi.nlm.nih.gov/pmc/articles/PMC8346284/
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHH212 nanobody targeting the hypoxia-inducible factor 1α suppresses angiogenesis and potentiates gemcitabine therapy in pancreatic cancer in vivo
    1
    1. scibot 15 Aug 2021
      RRID:CVCL_0480

      DOI: 10.20892/j.issn.2095-3941.2020.0568

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    ncbi.nlm.nih.gov/pmc/articles/PMC8330535/
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Muscle-Derived Cytokines Reduce Growth, Viability and Migratory Activity of Pancreatic Cancer Cells
    1
    1. scibot 15 Aug 2021
      RRID:CVCL_0480

      DOI: 10.3390/cancers13153820

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    ncbi.nlm.nih.gov/pmc/articles/PMC8345221/
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression
    1
    1. scibot 15 Aug 2021
      RRID:CVCL_0480

      DOI: 10.1158/2159-8290.CD-20-0775

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    ncbi.nlm.nih.gov/pmc/articles/PMC7858242/
  188. www.sciencedirect.com www.sciencedirect.com
    APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells
    1
    1. scibot 08 Aug 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.chembiol.2018.07.010

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2451945618302629
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 08 Aug 2021
      RRID:CVCL_0480

      DOI: 10.7554/eLife.29626

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5701795/
  190. www.sciencedirect.com www.sciencedirect.com
    Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy
    1
    1. scibot 05 Aug 2021
      87092802

      DOI: 10.1016/j.devcel.2021.07.006

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1534580721005621
  191. elifesciences.org elifesciences.org
    Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy
    1
    1. scibot 05 Aug 2021
      RRID:CVCL_0480

      DOI: 10.7554/eLife.29626

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    elifesciences.org/articles/29626
  192. www.mdpi.com www.mdpi.com
    CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines
    1
    1. scibot 01 Aug 2021
      RRID:CVCL_0480

      DOI: 10.3390/ijms20225706

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    mdpi.com/1422-0067/20/22/5706
  193. Jul 2021
  194. www.sciencedirect.com www.sciencedirect.com
    DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters
    1
    1. scibot 31 Jul 2021
      Panc-1

      DOI: 10.1016/j.celrep.2019.11.045

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S221112471931527X
  195. www.sciencedirect.com www.sciencedirect.com
    Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
    1
    1. scibot 30 Jul 2021
      PANC-1 (human)

      DOI: 10.1016/j.celrep.2019.08.068

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2211124719311234
  196. www.sciencedirect.com www.sciencedirect.com
    EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis
    1
    1. scibot 29 Jul 2021
      Panc-1

      DOI: 10.1016/j.devcel.2019.05.043

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    sciencedirect.com/science/article/pii/S153458071930485X
  197. www.sciencedirect.com www.sciencedirect.com
    Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells
    1
    1. scibot 27 Jul 2021
      CRL-1469

      DOI: 10.1016/j.cmet.2018.10.014

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    sciencedirect.com/science/article/pii/S1550413118306466
  198. www.sciencedirect.com www.sciencedirect.com
    KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
    1
    1. scibot 27 Jul 2021
      CRL-1469

      DOI: 10.1016/j.ccell.2018.10.001

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    sciencedirect.com/science/article/pii/S1535610818304677
  199. www.sciencedirect.com www.sciencedirect.com
    Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo
    2
    1. scibot 27 Jul 2021
      CVCL_0480

      DOI: 10.1016/j.ccell.2017.03.003

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      Curator: @Zeljana_Babic

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      RRIDCUR:Validated RRID:CVCL_0480
    2. scibot 27 Jul 2021
      CVCL_0480

      DOI: 10.1016/j.ccell.2017.03.003

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    sciencedirect.com/science/article/pii/S1535610817300995
  200. www.sciencedirect.com www.sciencedirect.com
    PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity
    1
    1. scibot 23 Jul 2021
      CRL-1469

      DOI: 10.1016/j.ccell.2021.06.018

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    sciencedirect.com/science/article/pii/S1535610821003408
  201. www.sciencedirect.com www.sciencedirect.com
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
    1
    1. scibot 22 Jul 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.ccell.2021.06.016

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    sciencedirect.com/science/article/pii/S153561082100338X
  202. www.sciencedirect.com www.sciencedirect.com
    ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors
    1
    1. scibot 22 Jul 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.xcrm.2021.100350

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2666379121001993
  203. www.sciencedirect.com www.sciencedirect.com
    CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity
    1
    1. scibot 20 Jul 2021
      CRL-1469

      DOI: 10.1016/j.chembiol.2021.06.007

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2451945621003068
  204. www.sciencedirect.com www.sciencedirect.com
    BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells
    1
    1. scibot 14 Jul 2021
      CRL-1469

      DOI: 10.1016/j.celrep.2021.109359

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2211124721007579
  205. Jun 2021
  206. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
    1
    1. scibot 30 Jun 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.celrep.2021.109291

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2211124721006628
  207. cancerres.aacrjournals.org cancerres.aacrjournals.org
    STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer
    1
    1. scibot 29 Jun 2021
      RRID:CVCL_0480

      DOI: 10.1158/0008-5472.CAN-20-2874

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    cancerres.aacrjournals.org/content/81/11/2943
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Gain-of-Function p53 R248W Mutant Promotes Migration by STAT3 Deregulation in Human Pancreatic Cancer Cells
    1
    1. scibot 29 Jun 2021
      CVCL_0480

      DOI: 10.3389/fonc.2021.642603

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8226097/
  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNA ELFN1-AS1 in the pathogenesis of pancreatic cancer
    1
    1. scibot 24 Jun 2021
      RRID:CVCL_0480

      DOI: 10.21037/atm-21-2376

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8184490/
  210. www.sciencedirect.com www.sciencedirect.com
    NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma
    1
    1. scibot 17 Jun 2021
      CRL-1469

      DOI: 10.1016/j.celrep.2021.109238

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2211124721005970
  211. May 2021
  212. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 20 May 2021
      RRID:CVCL_0480

      DOI: 10.1111/bph.15435

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15435
  213. www.sciencedirect.com www.sciencedirect.com
    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
    1
    1. scibot 15 May 2021
      CRL-1469

      DOI: 10.1016/j.molcel.2021.04.002

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1097276521002690
  214. www.sciencedirect.com www.sciencedirect.com
    Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells
    1
    1. scibot 12 May 2021
      CRL-1469

      DOI: 10.1016/j.devcel.2021.02.029

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1534580721001696
  215. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
    1
    1. scibot 10 May 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.cell.2021.04.016

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S0092867421004955
  216. www.sciencedirect.com www.sciencedirect.com
    Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice
    1
    1. scibot 09 May 2021
      RRID:CVCL_0480

      DOI: 10.1053/j.gastro.2020.11.044

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S001650852035513X
  217. www.sciencedirect.com www.sciencedirect.com
    Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis
    1
    1. scibot 05 May 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.devcel.2020.09.011

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1534580720307139
  218. www.sciencedirect.com www.sciencedirect.com
    The Source of Glycolytic Intermediates in Mammalian Tissues
    1
    1. scibot 01 May 2021
      CVCL_0480

      DOI: 10.1016/j.cmet.2020.12.020

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1550413120307282
  219. Apr 2021
  220. www.sciencedirect.com www.sciencedirect.com
    Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability
    1
    1. scibot 30 Apr 2021
      RRID: CVCL_0480

      DOI: 10.1016/j.cmet.2020.12.002

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1550413120306574
  221. www.sciencedirect.com www.sciencedirect.com
    Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
    1
    1. scibot 24 Apr 2021
      CRL-1469

      DOI: 10.1016/j.cell.2020.10.016

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S0092867420313222
  222. www.sciencedirect.com www.sciencedirect.com
    Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
    1
    1. scibot 24 Apr 2021
      CRL-1469

      DOI: 10.1016/j.cell.2020.07.009

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S0092867420308746
  223. www.sciencedirect.com www.sciencedirect.com
    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
    1
    1. scibot 22 Apr 2021
      RRID:CVCL_0480

      DOI: 10.1016/j.ccell.2021.02.016

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1535610821001185
  224. www.sciencedirect.com www.sciencedirect.com
    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
    1
    1. scibot 17 Apr 2021
      CRL-1469

      DOI: 10.1016/j.ccell.2020.04.014

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S1535610820302130
  225. www.sciencedirect.com www.sciencedirect.com
    The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
    1
    1. scibot 14 Apr 2021
      CRL-1469

      DOI: 10.1016/j.immuni.2021.03.008

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    sciencedirect.com/science/article/pii/S1074761321001205
  226. Mar 2021
  227. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Epithelial–Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer
    1
    1. scibot 31 Mar 2021
      RRID:CVCL_0480

      DOI: 10.3390/cancers13061469

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC8004805/
  228. Feb 2021
  229. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Human splenic TER cells: A relevant prognostic factor acting via the Artemin‐GFRα3‐ERK pathway in pancreatic ductal adenocarcinoma
    1
    1. scibot 27 Feb 2021
      RRID:CVCL_0480

      DOI: 10.1002/ijc.33410

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33410
  230. www.nature.com www.nature.com
    A multiwell plate-based system for toxicity screening under multiple static or cycling oxygen environments
    1
    1. scibot 25 Feb 2021
      PANC-1

      DOI: 10.1038/s41598-021-83579-1

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    nature.com/articles/s41598-021-83579-1
  231. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
    1
    1. scibot 24 Feb 2021
      PANC-1

      DOI: 10.1016/j.celrep.2021.108744

      Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)

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    sciencedirect.com/science/article/pii/S2211124721000577