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    Molecular mechanism of resistance to lonafarnib conferred by mutations in the cysteine-rich region of respiratory syncytial virus fusion glycoprotein and discovery of a lonafarnib-derived antiviral PROTAC
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    Nuclear Lamina Structure and Meiotic Chromosome Segregation Have Different Requirements for Dtopors-Mediated Ubiquitination in Male Drosophila melanogaster
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    Two CTCF motifs impede cohesin-mediated DNA loop extrusion
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  38. Dec 2025
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    Baseline AHR expression shapes immune response to pharmacological modulation in PBMCs from pancreatic cancer patients
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    Pan-cancer analysis of oncogenic MET fusions reveals distinct pathogenomic subsets with differential sensitivity to MET-targeted therapy
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    Insulin Resistance Increases TNBC Aggressiveness and Brain Metastasis via Adipocyte-derived Exosomes
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    Comprehensive characterization and targeted treatment of a pediatric epithelioid glioblastoma with a rare TRIM24-NTRK2 fusion
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    Ventilatory Complexity Persists in Phox2b Mutant Mice Lacking the Retrotrapezoid Nucleus/Parafacial Respiratory Group (RTN/pFRG) and in Humans With Congenital Central Hypoventilation Syndrome
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    Phosphorylation of MAP18 by MPK6 orchestrates microtubule reorganization in Arabidopsis during adaptation to salt stress
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    tRF-21LeuTAA Promotes Oxidative Stress by Altering Glutathione Metabolic Enzymes to Support Prostate Cancer Progression
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    Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer
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    Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti–PD-1 Immunotherapy
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    A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges during Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer
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    Protective ApoE variants support neuronal function by effluxing oxidized phospholipids
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    Jchain-Diphtheria Toxin Receptor Mice Allow for Depletion of Antibody-Secreting Cells and Analysis of Differentiation Kinetics
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    Dual role of Oct4 and Sox2 in controlling the developmental capacity and timing of tissue morphogenesis in the embryonic lineage
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    Modulation of relative aversive and safety learning by D2-expressing neurons of the anterior paraventricular nucleus of the thalamus
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    Aryl hydrocarbon receptor deficiency enhances astrocyte sensitivity to LPS-induced inflammation
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    Downregulation of Sod2 increases atypical flat lesions and dysplasia to advance pancreatic ductal adenocarcinoma
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    Inhibition of the UFD-1-NPL-4 complex triggers an aberrant immune response in Caenorhabditis elegans
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