5,847 Matching Annotations
  1. Feb 2024
  2. aacrjournals.org aacrjournals.org
    Inhibition of PORCN blocks Wnt signaling to attenuate progression of oral carcinogenesis
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    1. scibot 23 Feb 2024
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      DOI: 10.1158/1078-0432.CCR-23-0318

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    2. scibot 23 Feb 2024
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      DOI: 10.1158/1078-0432.CCR-23-0318

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    aacrjournals.org/clincancerres/article/30/1/209/732066/Inhibition-of-PORCN-Blocks-Wnt-Signaling-to
  3. aacrjournals.org aacrjournals.org
    R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1158/0008-5472.CAN-23-3239

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    aacrjournals.org/cancerres/article/84/4/577/734131/R-Loop-Accumulation-in-Spliceosome-Mutant
  4. aacrjournals.org aacrjournals.org
    TEAD Inhibition Overcomes YAP1/TAZ-driven Primary and Acquired Resistance to KRASG12C Inhibitors
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    1. scibot 23 Feb 2024
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      DOI: 10.1158/0008-5472.CAN-23-2994

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    2. scibot 23 Feb 2024
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      DOI: 10.1158/0008-5472.CAN-23-2994

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    aacrjournals.org/cancerres/article/83/24/4112/731546/TEAD-Inhibition-Overcomes-YAP1-TAZ-Driven-Primary
  5. 52.53.155.43 52.53.155.43
    can-23-1038-html.html
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    1. scibot 23 Feb 2024
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      DOI: 10.1158/0008-5472.can-23-1038

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    52.53.155.43/52e7b37fca465450e68864b868e33c5f6d45d858/84-html.html
  6. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
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    1. scibot 23 Feb 2024
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      DOI: 10.1158/0008-5472.can-23-0555

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    52.53.155.43/e8db3efafb8a8253e8641e16f59e9a4a6a668dad/can-23-0555-html.html
  7. www.sciencedirect.com www.sciencedirect.com
    An iron rheostat controls hematopoietic stem cell fate
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.stem.2024.01.011

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    sciencedirect.com/science/article/pii/S1934590924000419
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1158/1078-0432.CCR-23-2378

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    ncbi.nlm.nih.gov/pmc/articles/PMC10870201/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of α-synuclein in vitro aggregation kinetics by its alternative splice isoforms
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1073/pnas.2313465121

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    ncbi.nlm.nih.gov/pmc/articles/PMC10873642/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKCμ promotes keratinocyte cell migration through Cx43 phosphorylation-mediated suppression of intercellular communication
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.isci.2024.109033

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    ncbi.nlm.nih.gov/pmc/articles/PMC10875573/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative modelling and analysis of signalling crosstalk reveal molecular switches coordinating YAP transcriptional activities
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.isci.2024.109031

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    ncbi.nlm.nih.gov/pmc/articles/PMC10877689/
  12. 52.53.155.43 52.53.155.43
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
    1
    1. scibot 22 Feb 2024
      RRID:SCR_003070

      DOI: 10.1101/2023.09.27.559698

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    52.53.155.43/9b07aa3872d935df1f2ff4d73fc96f76996bcf22/2023.09.27.559698v1.full-html.html
  13. 52.53.155.43 52.53.155.43
    Combined repetitive inhalant endotoxin and collagen-induced arthritis drives inflammatory lung disease and arthritis severity in a testosterone-dependent manner
    2
    1. scibot 22 Feb 2024
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      DOI: 10.1152/ajplung.00221.2023

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    2. scibot 22 Feb 2024
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      DOI: 10.1152/ajplung.00221.2023

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    52.53.155.43/d4f6e6a407021b1ce81f693820e55c2451649406/poole-et-al-2024-combined-repetitive-inhalant-endotoxin-and-collagen-induced-arthritis-drive-inflammatory-lung-disease-html.html
  14. 52.53.155.43 52.53.155.43
    keeler-et-al-2023-a-potent-mapk13-14-inhibitor-prevents-airway-inflammation-and-mucus-production-html.html
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      DOI: 10.1152/ajplung.00183.2023

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      DOI: 10.1152/ajplung.00183.2023

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    52.53.155.43/351fb10b4cf800e0fd91f74b500407db1fedf77c/keeler-et-al-2023-a-potent-mapk13-14-inhibitor-prevents-airway-inflammation-and-mucus-production-html.html
  15. 52.53.155.43 52.53.155.43
    A modified mouse model of Friedreich's ataxia with conditional Fxn allele homozygosity delays onset of cardiomyopathy
    2
    1. scibot 22 Feb 2024
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      DOI: 10.1152/ajpheart.00496.2023

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      DOI: 10.1152/ajpheart.00496.2023

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    52.53.155.43/6e33d55472e195d6adca9c28447508adb76e083a/perfitt-et-al-2024-a-modified-mouse-model-of-friedreich-s-ataxia-with-conditional-fxn-allele-homozygosity-delays-onset-html.html
  16. 52.53.155.43 52.53.155.43
    Dual amylin and calcitonin receptor agonist treatment reduces biomarkers associated with kidney fibrosis in diabetic rats
    2
    1. scibot 22 Feb 2024
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      DOI: 10.1152/ajpendo.00245.2023

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    2. scibot 22 Feb 2024
      RRID:SCR_003070

      DOI: 10.1152/ajpendo.00245.2023

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    52.53.155.43/04456dd5a135449c94626e0786262a1d58d4410c/melander-et-al-2023-dual-amylin-and-calcitonin-receptor-agonist-treatment-reduces-biomarkers-associated-with-kidney-html.html
  17. link.springer.com link.springer.com
    Floating electrode–dielectric barrier discharge-based plasma promotes skin regeneration in a full-thickness skin defect mouse model
    1
    1. scibot 22 Feb 2024
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      DOI: 10.1007/s13534-024-00356-5

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    link.springer.com/article/10.1007/s13534-024-00356-5
  18. link.springer.com link.springer.com
    Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Radix Paeoniae Rubra Against Glioma
    1
    1. scibot 22 Feb 2024
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      DOI: 10.1007/s12010-024-04887-6

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    link.springer.com/article/10.1007/s12010-024-04887-6
  19. www.sciencedirect.com www.sciencedirect.com
    IL-37d enhances COP1-mediated C/EBPβ degradation to suppress spontaneous neutrophil migration and tumor progression
    1
    1. scibot 22 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113787

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    sciencedirect.com/science/article/pii/S2211124724001153
  20. www.sciencedirect.com www.sciencedirect.com
    Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia
    1
    1. scibot 22 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113776

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    sciencedirect.com/science/article/pii/S2211124724001049
  21. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Advanced age and female sex protect cerebral arteries from mitochondrial depolarization and apoptosis during acute oxidative stress
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    1. scibot 22 Feb 2024
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      DOI: 10.1111/acel.14110

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    onlinelibrary.wiley.com/doi/10.1111/acel.14110
  22. www.sciencedirect.com www.sciencedirect.com
    A metabolically controlled contact site between vacuoles and lipid droplets in yeast
    3
    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.devcel.2024.01.016

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    2. scibot 21 Feb 2024
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      DOI: 10.1016/j.devcel.2024.01.016

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    3. scibot 21 Feb 2024
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      DOI: 10.1016/j.devcel.2024.01.016

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    sciencedirect.com/science/article/pii/S1534580724000364
  23. www.sciencedirect.com www.sciencedirect.com
    Neonatal brain injury unravels transcriptional and signaling changes underlying the reactivation of cortical progenitors
    1
    1. scibot 18 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113734

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    sciencedirect.com/science/article/pii/S2211124724000627
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biomimetic proteolipid vesicles for reverting GPI deficiency in paroxysmal nocturnal hemoglobinuria
    1
    1. scibot 18 Feb 2024
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      DOI: 10.1016/j.isci.2024.109021

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    ncbi.nlm.nih.gov/pmc/articles/PMC10867660/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lingual Denervation Improves the Efficacy of Anti-PD-1 Immunotherapy in Oral Squamous Cell Carcinomas by Down-regulating TGFβ Signaling
    1
    1. scibot 18 Feb 2024
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      DOI: 10.1158/2767-9764.CRC-23-0192

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    ncbi.nlm.nih.gov/pmc/articles/PMC10868515/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temozolomide sensitizes ARID1A-mutated cancers to PARP inhibitors
    1
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      DOI: 10.1158/0008-5472.CAN-22-3646

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527942/
  27. www.sciencedirect.com www.sciencedirect.com
    SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway
    1
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      DOI: 10.1016/j.devcel.2024.01.024

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    sciencedirect.com/science/article/pii/S1534580724000443
  28. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.16283

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
  29. content.iospress.com content.iospress.com
    Sex-Dependent Effects of Chronic Circadian Disruption in AβPP/PS1 Mice
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      DOI: 10.3233/JAD-230089

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    content.iospress.com/articles/journal-of-alzheimers-disease/jad230089
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytic enzyme PFKFB3 regulates sphingosinae 1-phosphate receptor 1 in proangiogenic glomerular endothelial cells under diabetic condition
    1
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      DOI: 10.1152/ajpcell.00261.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10861147/
  31. www.biorxiv.org www.biorxiv.org
    Parkinson's disease-related Miro1 mutation induces mitochondrial dysfunction and loss of dopaminergic neurons in vitro and in vivo
    2
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      DOI: 10.1101/2023.12.19.571978

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      DOI: 10.1101/2023.12.19.571978

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    biorxiv.org/content/10.1101/2023.12.19.571978v1
  32. www.biorxiv.org www.biorxiv.org
    HURP facilitates spindle assembly by stabilizing microtubules and working synergistically with TPX2
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    1. scibot 15 Feb 2024
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      DOI: 10.1101/2023.12.18.571906

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    biorxiv.org/content/10.1101/2023.12.18.571906v1
  33. www.biorxiv.org www.biorxiv.org
    Age-Related Changes of Dopamine D1 and D2 Receptors Expression in Parvalbumin-Positive Cells of the Orbitofrontal and Prelimbic Cortices of Mice
    1
    1. scibot 15 Feb 2024
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      DOI: 10.1101/2023.12.17.571962

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    biorxiv.org/content/10.1101/2023.12.17.571962v1
  34. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Role of paraoxonase 3 in regulating ENaC-mediated Na+ transport in the distal nephron
    1
    1. scibot 15 Feb 2024
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      DOI: 10.1113/JP285034

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    NMDA glutamate receptor antagonist MK-801 induces proteome changes in adult human brain slices which are partially counteracted by haloperidol and clozapine
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    Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer
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    Midbrain neurons important for the production of mouse ultrasonic vocalizations are not required for distress calls
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    Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle
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    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
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    Androgen receptor deficiency is associated with reduced aromatase expression in the ventromedial hypothalamus of male cichlids
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    A Novel Macrolide–Del-1 Axis to Regenerate Bone in Old Age
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    BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
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    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants
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    The Oncolytic Activity of Zika Viral Therapy in Human Neuroblastoma In Vivo Models Confers a Major Survival Advantage in a CD24-dependent Manner
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    Two-Step Actions of Testicular Androgens in the Organization of a Male-Specific Neural Pathway from the Medial Preoptic Area to the Ventral Tegmental Area for Modulating Sexually Motivated Behavior
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    A Dynamic Balance between Neuronal Death and Clearance in an in Vitro Model of Acute Brain Injury
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    Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo
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    Age-Related Palatal Wound Healing: An Experimental In Vivo Study
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    Cadmium promotes the binding and centrosomal translocation of CCDC85C and PLK4 via ROS-GCLM pathway to trigger centrosome amplification in colon cancer cells
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    Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson’s Disease
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    Recombinant Full-Length TDP-43 Oligomers Retain Their Ability to Bind RNAs, Are Not Toxic, and Do Not Seed TDP-43 Aggregation in Vitro
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    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    Avoidance and escape conditioning adjust adult neurogenesis to conserve a fit hippocampus in adult male rodents
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    Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis
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    The potential use of ascorbic acid to recover the cellular senescence of lipopolysaccharide-induced human apical papilla cells: an in vitro study
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    Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity
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    ADSC-Exos outperform BMSC-Exos in alleviating hydrostatic pressure-induced injury to retinal ganglion cells by upregulating nerve growth factors
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    Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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    Myeloma extracellular vesicle-derived RAGE increases inflammatory responses and myotube atrophy in multiple myeloma through activation of the TLR4/NF-κB p65 pathway
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    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
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    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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    Antenatal Dexamethasone Treatment Induces Sex-dependent Upregulation of NTPDase1/CD39 and Ecto-5ʹ-nucleotidase/CD73 in the Rat Fetal Brain
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    Reducing the prosthesis modulus by inclusion of an open space lattice improves osteogenic response in a sheep model of extraarticular defect
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    From biosynthesis and beyond—Loss or overexpression of the cytokinin synthesis gene, iptA, alters cytokinesis and mitochondrial and amino acid metabolism in Dictyostelium discoideum
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    Golgi-to-ER retrograde transport prevents premature differentiation of Drosophila type II neuroblasts via Notch-signal-sending daughter cells
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    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
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    A cluster of neuropeptide S neurons regulates breathing and arousal
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    Purkinje-cell-specific MeCP2 deficiency leads to motor deficits and autistic-like behavior due to aberrations in PTP1B-TrkB-SK signaling
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    Regulation of stress-induced sleep fragmentation by preoptic glutamatergic neurons
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    Mechanical regulation of substrate adhesion and de-adhesion drives a cell-contractile wave during Drosophila tissue morphogenesis
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    Protocol for measuring protein synthesis in specific cell types in the mouse brain using in vivo non-canonical amino acid tagging
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  156. www.mdpi.com www.mdpi.com
    Omega-3 Recovers Cannabinoid 1 Receptor Expression in the Adult Mouse Brain after Adolescent Binge Drinking
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      DOI: 10.3390/ijms242417316

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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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      DOI: 10.7554/eLife.87098

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    A vasopressin circuit that modulates sex-specific social interest and anxiety-like behavior in mice
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interleukin-30 subverts prostate cancer-endothelium crosstalk by fostering angiogenesis and activating immunoregulatory and oncogenic signaling pathways
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    Hexavalent-Chromium-Induced Disruption of Mitochondrial Dynamics and Apoptosis in the Liver via the AMPK-PGC-1α Pathway in Ducks
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  161. f1000research.com f1000research.com
    Evaluation of the merit of ethanolic extract of <i>Annona reticulata</i> as an anti-cancer agent in human colon cancer cell lines (HCT-116)
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  162. www.mdpi.com www.mdpi.com
    Berberine Protects against High-Energy and Low-Protein Diet-Induced Hepatic Steatosis: Modulation of Gut Microbiota and Bile Acid Metabolism in Laying Hens
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional maturation of human iPSC-derived pyramidal neurons in vivo is dependent on proximity with the host tissue
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    Socrates: A Novel N-Ethyl-N-nitrosourea-Induced Mouse Mutant with Audiogenic Epilepsy
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    Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation
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    Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging
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      DOI: 10.7554/eLife.91263

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    Statin-induced mitochondrial priming sensitizes multiple myeloma cells to BCL2 and MCL1 inhibitors
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic landscape of the intracellular termini of acid-sensing ion channel 1a
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  169. journals.sagepub.com journals.sagepub.com
    Urokinase-type plasminogen activator promotes N-cadherin-mediated synaptic recovery in the ischemic brain - Ariel Diaz, Paola Merino, Patrick McCann, Manuel A Yepes, Laura G Quiceno, Enrique Torre, Amelia Tomkins, Xiaodong Zhang, Chadwick M Hales, Frank C Tong, Manuel Yepes, 2021
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  170. link.springer.com link.springer.com
    Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications
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    PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors
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    Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression
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    Role of miR-379 in high-fat diet-induced kidney injury and dysfunction
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  174. www.sciencedirect.com www.sciencedirect.com
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
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    MiR-324-5p inhibition after intrahippocampal kainic acid-induced status epilepticus does not prevent epileptogenesis in mice
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      DOI: 10.3389/fneur.2023.1280606

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  177. rupress.org rupress.org
    Integration of cell wall synthesis and chromosome segregation during cell division in Caulobacter
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      DOI: 10.1083/jcb.202211026

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  178. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Blockage of the fractalkine pathway reduces hyperalgesia and prevents morphological glial alterations—Comparison between inflammatory and neuropathic orofacial pain in male rats
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      DOI: 10.1002/jnr.25269

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  179. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor effects of chemically modified miR-143 lipoplexes in a colorectal cancer pelvic recurrence mouse model are mediated via downregulation of myristoylated alanine-rich C kinase substrate
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  180. link.springer.com link.springer.com
    The DNA/RNA helicase DHX9 orchestrates the KDM2B-mediated transcriptional regulation of YAP1 in Ewing sarcoma
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      DOI: 10.1038/s41388-023-02894-1

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    Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer
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      DOI: 10.1158/1078-0432.CCR-22-3350

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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma
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      DOI: 10.1158/0008-5472.CAN-23-1356

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