912 Matching Annotations
  1. Last 7 days
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    Feedforward and disinhibitory circuits differentially control activity of cortical somatostatin interneurons during behavioral state transitions
    1
    1. scibot 14 May 2024
      SCR_011323

      DOI: 10.1016/j.celrep.2024.114197

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    sciencedirect.com/science/article/pii/S2211124724005254
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    The adipose-neural axis is involved in epicardial adipose tissue-related cardiac arrhythmias
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    1. scibot 14 May 2024
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      DOI: 10.1016/j.xcrm.2024.101559

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    sciencedirect.com/science/article/pii/S2666379124002519
  4. May 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of Midbrain Dopamine Neurons Does Not Alter GABAergic Inhibition Mediated by Parvalbumin-Expressing Interneurons in Mouse Primary Motor Cortex
    1
    1. scibot 12 May 2024
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      DOI: 10.1523/ENEURO.0010-24.2024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11082919/
  6. 52.53.155.43 52.53.155.43
    Chemogenetic silencing reveals presynaptic Gi/o protein-mediated inhibition of synchronized activity in the developing hippocampus<i>in vivo</i>
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    1. scibot 10 May 2024
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      DOI: 10.1101/2024.02.02.578550

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    52.53.155.43/99b8ae5994ab6ffcaaf69cc4c284d23ddd6a77c1/2024.02.02.578550v1.full-html.html
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    Behavioral control through the direct, focal silencing of neuronal activity
    1
    1. scibot 10 May 2024
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      DOI: 10.1016/j.chembiol.2024.04.003

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    sciencedirect.com/science/article/pii/S2451945624001314
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    Astroglial gap junctions strengthen hippocampal network activity by sustaining afterhyperpolarization via KCNQ channels
    1
    1. scibot 09 May 2024
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      DOI: 10.1016/j.celrep.2024.114158

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    sciencedirect.com/science/article/pii/S2211124724004868
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    Oxytocin and corticotropin-releasing hormone exaggerate nucleus tractus solitarii neuronal and synaptic activity following chronic intermittent hypoxia
    1
    1. scibot 09 May 2024
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      DOI: 10.1113/JP286069

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    physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP286069
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    Morphological Tracing and Functional Identification of Monosynaptic Connections in the Brain: A Comprehensive Guide
    1
    1. scibot 09 May 2024
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      DOI: 10.1007/s12264-024-01196-0

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    link.springer.com/article/10.1007/s12264-024-01196-0
  11. Apr 2024
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    Higher-order thalamocortical circuits are specified by embryonic cortical progenitor types in the mouse brain
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114157

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    sciencedirect.com/science/article/pii/S2211124724004856
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The lactate receptor HCAR1: A key modulator of epileptic seizure activity
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    1. scibot 28 Apr 2024
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      DOI: 10.1016/j.isci.2024.109679

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    ncbi.nlm.nih.gov/pmc/articles/PMC11035371/
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    LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction
    1
    1. scibot 28 Apr 2024
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      DOI: 10.7554/eLife.92411

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    ncbi.nlm.nih.gov/pmc/articles/PMC11037915/
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    Increased glutamatergic neurotransmission between the retinohypothalamic tract and the suprachiasmatic nucleus of old mice
    1
    1. scibot 25 Apr 2024
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      DOI: 10.1002/jnr.25331

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    onlinelibrary.wiley.com/doi/10.1002/jnr.25331
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    Sex-specific expression of distinct serotonin receptors mediates stress vulnerability of adult hippocampal neural stem cells in mice
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    1. scibot 25 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114140

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    sciencedirect.com/science/article/pii/S2211124724004686
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    The endoplasmic reticulum plays a key role in α-cell intracellular Ca2+ dynamics and glucose-regulated glucagon secretion in mouse islets
    1
    1. scibot 23 Apr 2024
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      DOI: 10.1016/j.isci.2024.109665

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    ncbi.nlm.nih.gov/pmc/articles/PMC11033163/
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    Morpho-electric diversity of human hippocampal CA1 pyramidal neurons
    1
    1. scibot 19 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114100

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    sciencedirect.com/science/article/pii/S2211124724004285
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The scale of zebrafish pectoral fin buds is determined by intercellular K+ levels and consequent Ca2+-mediated signaling via retinoic acid regulation of Rcan2 and Kcnk5b
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    1. scibot 18 Apr 2024
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      DOI: 10.1371/journal.pbio.3002565

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    ncbi.nlm.nih.gov/pmc/articles/PMC11018282/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation
    1
    1. scibot 18 Apr 2024
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      DOI: 10.1038/s41531-024-00694-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014935/
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    Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity
    1
    1. scibot 17 Apr 2024
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      DOI: 10.1186/s13024-024-00721-z

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    link.springer.com/article/10.1186/s13024-024-00721-z
  22. 52.53.155.43 52.53.155.43
    elife-89520-v1-html.html
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    1. scibot 13 Apr 2024
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      DOI: 10.7554/elife.89520

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    52.53.155.43/c3b1e6d8d2de56fd025e62b2bcc3730f225b8b2d/elife-89520-v1-html.html
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atypical retinal function in a mouse model of Fragile X syndrome
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1101/2024.03.15.585283

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    ncbi.nlm.nih.gov/pmc/articles/PMC10980068/
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    scRNA-seq data from the larval Drosophila ventral cord provides a resource for studying motor systems function and development
    1
    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.016

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    sciencedirect.com/science/article/pii/S1534580724001862
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    BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing
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    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114025

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    sciencedirect.com/science/article/pii/S221112472400353X
  26. Mar 2024
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    Restoration of a paraventricular thalamo-accumbal behavioral suppression circuit prevents reinstatement of heroin seeking
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      DOI: 10.1016/j.neuron.2023.11.024

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    sciencedirect.com/science/article/pii/S0896627323009285
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Na+ leak channel NALCN controls spontaneous activity and mediates synaptic modulation by α2-adrenergic receptors in auditory neurons
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    1. scibot 23 Mar 2024
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      DOI: 10.7554/eLife.89520

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    ncbi.nlm.nih.gov/pmc/articles/PMC10945507/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of SMN protein in mesenchymal progenitors impairs the development of bone and neuromuscular junction in spinal muscular atrophy
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    1. scibot 23 Mar 2024
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      DOI: 10.7554/eLife.92731

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    ncbi.nlm.nih.gov/pmc/articles/PMC10945524/
  30. 52.53.155.43 52.53.155.43
    Evaluating sequential and allosteric activation models in IKs channels with mutated voltage sensors
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    1. scibot 21 Mar 2024
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      DOI: 10.1085/jgp.202313465

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    2. scibot 21 Mar 2024
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      DOI: 10.1085/jgp.202313465

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    3. scibot 21 Mar 2024
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      DOI: 10.1085/jgp.202313465

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    52.53.155.43/ce01f1e6e7ee5d5047b315ea07e51446fb5b3f93/jgp_202313465-html.html
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperactivity of mTORC1- and mTORC2-dependent signaling mediates epilepsy downstream of somatic PTEN loss
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    1. scibot 17 Mar 2024
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      DOI: 10.7554/eLife.91323

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942640/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mTOR pathway genes MTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function
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    1. scibot 17 Mar 2024
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      DOI: 10.7554/eLife.91010

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942629/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel GABAergic population in the medial vestibular nucleus maintains wakefulness and gates rapid eye movement sleep
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      DOI: 10.1016/j.isci.2024.109289

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    ncbi.nlm.nih.gov/pmc/articles/PMC10933495/
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    Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells: A mechanistic connection between the kidney defects in cpk mice and human ARPKD
    1
    1. scibot 16 Mar 2024
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      DOI: 10.1096/fj.202300100R

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    ncbi.nlm.nih.gov/pmc/articles/PMC10929748/
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Role of M4-receptor cholinergic signaling in direct pathway striatal projection neurons during dopamine depletion
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      DOI: 10.1002/syn.22287

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    onlinelibrary.wiley.com/doi/10.1002/syn.22287
  36. www.sciencedirect.com www.sciencedirect.com
    LncRNA Litchi is a Regulator for Harmonizing Maturity and Resilient Functionality in Spinal Motor Neurons
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      DOI: 10.1016/j.isci.2024.109207

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      DOI: 10.1016/j.isci.2024.109207

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    sciencedirect.com/science/article/pii/S2589004224004280
  37. www.sciencedirect.com www.sciencedirect.com
    Multimodal sensory control of motor performance by glycinergic interneurons of the mouse spinal cord deep dorsal horn
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      DOI: 10.1016/j.neuron.2024.01.027

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      DOI: 10.1016/j.neuron.2024.01.027

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    sciencedirect.com/science/article/pii/S0896627324000539
  38. Feb 2024
  39. 52.53.155.43 52.53.155.43
    riggs-et-al-2024-camp-dependent-protein-kinase-signaling-is-required-for-(2r-6r)-hydroxynorketamine-to-potentiate-html.html
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    1. scibot 22 Feb 2024
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      DOI: 10.1152/jn.00326.2023

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    52.53.155.43/069fe0cb1fb4ef2dc3bd0c4ad3b7cdaca4f51435/riggs-et-al-2024-camp-dependent-protein-kinase-signaling-is-required-for-(2r-6r)-hydroxynorketamine-to-potentiate-html.html
  40. www.sciencedirect.com www.sciencedirect.com
    Acetylcholine synergizes with netrin-1 to drive persistent firing in the entorhinal cortex
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    sciencedirect.com/science/article/pii/S2211124724001402
  41. www.jneurosci.org www.jneurosci.org
    Calcium-sensitive subthreshold oscillations and electrical coupling in principal cells of mouse dorsal cochlear nucleus
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      DOI: 10.1523/JNEUROSCI.0106-20.2023

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    jneurosci.org/content/44/6/e0106202023
  42. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Role of paraoxonase 3 in regulating ENaC-mediated Na+ transport in the distal nephron
    1
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      DOI: 10.1113/JP285034

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    Physical and functional convergence of the autism risk genes Scn2a and Ank2 in neocortical pyramidal cell dendrites
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    Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons
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    Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channels
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    Transgenic Tg(Kcnj10-ZsGreen) Fluorescent Reporter Mice Allow Visualization of Intermediate Cells in the Stria Vascularis
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  73. Oct 2023
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    Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons
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    Negative valence encoding in the lateral entorhinal cortex during aversive olfactory learning
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  82. Sep 2023
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    The thalamic reticular nucleus-lateral habenula circuit regulates depressive-like behaviors in chronic stress and chronic pain
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    Loss of oxytocin receptors in hilar mossy cells impairs social discrimination
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  87. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Adaptive spike threshold dynamics associated with sparse spiking of hilar mossy cells are captured by a simple model
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Active shrinkage protects neurons following axonal transection
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    Organization of Purkinje cell development by neuronal MEGF11 in cerebellar granule cells
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  90. Aug 2023
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced thalamic excitation to motor cortical pyramidal tract neurons in parkinsonism
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    Different mechanisms of synapsin-induced vesicle clustering at inhibitory and excitatory synapses
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    ATP modulates the activity of the voltage-gated proton channel through direct binding interaction
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  95. 52.53.155.43 52.53.155.43
    Ventral pallidal glutamatergic neurons regulate wakefulness and emotion through separated projections
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    Astrocytes adjust the dynamic range of cortical network activity to control modality-specific sensory information processing
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    Muscarinic Acetylcholine Receptors Modulate HCN Channel Properties in Vestibular Ganglion Neurons
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    Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease
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    Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling
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  100. Jul 2023
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    Anterior hypothalamic parvalbumin neurons are glutamatergic and promote escape behavior
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    Human neutrophils communicate remotely via calcium-dependent glutamate-induced glutamate release
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    Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice
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    Cortical regulation of neurogenesis and cell proliferation in the ventral subventricular zone
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    Orexin recruits non-selective cationic conductance and endocannabinoid to dynamically modulate firing of caudal pontine reticular nuclear neurones
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    Shedding light on human olfaction: Electrophysiological recordings from sensory neurons in acute slices of olfactory epithelium
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    Lateral septum as a melanocortin downstream site in obesity development
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    Two parallel medial prefrontal cortex-amygdala pathways mediate memory deficits via glutamatergic projection in surgery mice
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  109. Jun 2023
  110. elifesciences.org elifesciences.org
    Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing
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    Glutamine Supplementation Preserves Glutamatergic Neuronal Activity in the Infralimbic Cortex, Which Delays the Onset of Mild Cognitive Impairment in 3×Tg-AD Female Mice
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    Labeling PIEZO2 activity in the peripheral nervous system
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    Preclinical Examination of Early-Onset Thalamic–Cortical Seizures after Hemispheric Stroke
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    The temporal pattern of synaptic activation determines the longevity of plasticity at single dendritic spines
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    ElecFeX: A user-friendly toolkit for efficient feature extraction from single-cell electrophysiological recordings
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  117. May 2023
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    Dopaminergic and prefrontal dynamics co-determine mouse decisions in a spatial gambling task
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    Inhibiting neuronal AC1 for treating anxiety and headache in the animal model of migraine
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    Involvement of Mrgprd-expressing nociceptors-recruited spinal mechanisms in nerve injury-induced mechanical allodynia
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    Lateral septum as a melanocortin downstream site in obesity development
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    Enhanced functional detection of synaptic calcium-permeable AMPA receptors using intracellular NASPM
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    Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex
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    Developmental switch in the function of inhibitory commissural V0d interneurons in zebrafish
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  126. Apr 2023
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    Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict
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    Asymmetric mechanotransduction by hair cells of the zebrafish lateral line
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    The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus
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    Activation of hypothalamic-enhanced adult-born neurons restores cognitive and affective function in Alzheimer’s disease
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    γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons
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    Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer’s disease
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    Ketone bodies promote stroke recovery via GAT-1-dependent cortical network remodeling
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    Volume-transmitted GABA waves pace epileptiform rhythms in the hippocampal network
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    Transcriptional control of nucleus accumbens neuronal excitability by retinoid X receptor alpha tunes sensitivity to drug rewards
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    Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation
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    Neural mechanism underlies CYLD modulation of morphology and synaptic function of medium spiny neurons in dorsolateral striatum
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  146. Feb 2023
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    Design, synthesis, and evaluation of hydrazones as dual inhibitors of ryanodine receptors and acetylcholinesterases for Alzheimer’s disease
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    The lipid transporter ORP2 regulates synaptic neurotransmitter release via two distinct mechanisms
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    Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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    EGFR-dependent suppression of synaptic autophagy is required for neuronal circuit development
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    Piezo2 channels expressed by colon-innervating TRPV1-lineage neurons mediate visceral mechanical hypersensitivity
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    Neuronal and astrocytic contributions to Huntington’s disease dissected with zinc finger protein transcriptional repressors
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones
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    Brainstem circuits encoding start, speed, and duration of swimming in adult zebrafish
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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Madm/NRBP1 mediates synaptic maintenance and neurodegeneration-induced presynaptic homeostatic potentiation
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  174. Nov 2022
  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X
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  176. www.nature.com www.nature.com
    Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neurons
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutathione in the nucleus accumbens regulates motivation to exert reward-incentivized effort
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An in vitro whole-cell electrophysiology dataset of human cortical neurons
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  180. journals.plos.org journals.plos.org
    Long-range axonal projections of transplanted mouse embryonic stem cell-derived hypothalamic neurons into adult mouse brain
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    Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain
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  182. pubs.acs.org pubs.acs.org
    Subtype-Selective Positive Modulation of K Ca 2.3 Channels Increases Cilia Length
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental regulation of thalamus-driven pauses in striatal cholinergic interneurons
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    Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss
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  185. Oct 2022
  186. www.jneurosci.org www.jneurosci.org
    µ-Opioid Receptor Activation Reduces Glutamate Release in the preBötzinger Complex in Organotypic Slice Cultures
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  187. www.sciencedirect.com www.sciencedirect.com
    De novo establishment of circuit modules restores locomotion after spinal cord injury in adult zebrafish
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    Isolation and Electrophysiology of Murine Sympathetic Postganglionic Neurons in the Thoracic Paravertebral Ganglia
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    Hypothalamic astrocytes control systemic glucose metabolism and energy balance
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    Functional analysis of a bitter gustatory receptor highly expressed in the larval maxillary galea of Helicoverpa armigera
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker
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  192. Sep 2022
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcium/calmodulin-dependent protein kinase II associates with the K+ channel isoform Kv4.3 in adult rat optic nerve
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    Selective protein kinase C inhibition switches time-dependent glucose cardiotoxicity to cardioprotection
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    Seizures, behavioral deficits, and adverse drug responses in two new genetic mouse models of HCN1 epileptic encephalopathy
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    An oxytocinergic neural pathway that stimulates thermogenic and cardiac sympathetic outflow
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    Postnatal age-differential ASD-like transcriptomic, synaptic, and behavioral deficits in Myt1l-mutant mice
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    Chronic neurotransmission increases the susceptibility of lateral-line hair cells to ototoxic insults
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    Linking transcriptomes with morphological and functional phenotypes in mammalian retinal ganglion cells
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    Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior
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  201. Aug 2022
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    Role of 5-HT2A receptor in modulating glutamatergic activity in the ventrolateral orbital cortex: implication in trigeminal neuralgia
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  203. pubs.acs.org pubs.acs.org
    Subtype-Selective Positive Modulation of K Ca 2.3 Channels Increases Cilia Length
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    Sustained deep-tissue voltage recording using a fast indicator evolved for two-photon microscopy
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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tricyclic antipsychotics and antidepressants can inhibit α5‐containing GABAA receptors by two distinct mechanisms
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  207. Jul 2022
  208. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  209. www.jneurosci.org www.jneurosci.org
    Modulating the excitability of olfactory output neurons affects whole-body metabolism
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  210. elifesciences.org elifesciences.org
    β2-subunit alternative splicing stabilizes Cav2.3 Ca2+ channel activity during continuous midbrain dopamine neuron-like activity
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    VMHvllCckar cells dynamically control female sexual behaviors over the reproductive cycle
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  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The E3 ligase Thin controls homeostatic plasticity through neurotransmitter release repression
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