5,106 Matching Annotations
- May 2021
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europepmc.org europepmc.org
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tissues
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COVID-19
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transcriptional pathways
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cellular
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disruption
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cell expression state
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splicing isoform switching
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lung tissues
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cardiac
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cellular expression states
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expression
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T cell receptor
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splicing isoforms
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transcriptional dysregulation
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infection
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viral load
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SARS-CoV-2 infection
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lymph nodes
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kidney
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lung
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liver
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heart
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tissue sections
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spatial protein and expression profiling
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patient
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autopsy tissues
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nasopharyngeal swabs
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challenges
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transcriptional profiling
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ARDS
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Acute Respiratory Distress Syndrome
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lung injury
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seasonal influenza virus
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COVID-19
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clinical manifestations
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molecular mechanisms
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worldwide
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deaths
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people
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SARS-CoV-2
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Severe Acute Respiratory Syndrome Coronavirus 2
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- Apr 2021
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europepmc.org europepmc.org
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RCA algorithm
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scalable
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supervised clustering
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batch effects
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reference transcriptomes
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supervised clustering
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de novo (unsupervised) clustering methods
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technical
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biological, variation.
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cluster cells
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unsupervised clustering algorithms
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technical variation
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single cell clustering
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subtypes
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cell types
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technique
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default
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cellular transcriptome
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clustering
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single cell (SC) technologies
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human body
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cell types
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transcriptomic
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diversity
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-
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COVID-19
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cellular responses
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host tissue immune
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multiple-organ failures
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acute respiratory distress syndrome,
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acute lung injury
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globally
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deaths
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SARS-CoV-2 pandemic
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europepmc.org europepmc.org
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blood
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airways
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immune responses
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children
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reference
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user-friendly interface
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infection
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spatial dynamics
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samples
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airway
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blood
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dult COVID-19.
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severe paediatri
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gene signature
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eutrophil-recruiting
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antiviral
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Epithelial cells
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patients
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adult COVID-19
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paediatric
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healthy children
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ciliated cells
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secretory
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transitional regenerative state
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cells
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cell population
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inflammatory epithelial cell
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ciliated cell
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goblet
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viral load
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airway epithelium
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signature
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interferon-response
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peripheral blood
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non-clonally expanded naive T cells
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innate lymphoid
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COVID-19
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adults
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children
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blood
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lower airways
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upper
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COVID-19 patients
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adult COVID-19
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severe paediatric
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innate immunity
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hallmarks
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gene expression signature
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infants
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neonates
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T lymphocytes
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naive B
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adolescence
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childhood
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infancy
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cell populations
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blood
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airway
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developmental
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tracheal brushings
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nasal
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matched samples
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children
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single cell data set
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multi-omics single cell
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pathogenesis
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SARS-CoV-2 infection
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adults
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children
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SARS-CoV-2 infection
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local
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systemic response
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respiratory complications
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children
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SARS-CoV-2
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adults
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severe disease
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europepmc.org europepmc.org
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diseases
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centers
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COVID-19
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multi-omic
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COVID-19
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acute immune response
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peripheral blood
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cellular processes
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data
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intuitive
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web portal
-
data mining
-
results
-
analysis
-
data
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disease severity
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BCR
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plasma cells
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IgG plasmablasts
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asymptomatic stages
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IgA plasmablasts
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disease
-
patients
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CD8 + T cells
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proliferating CD4 +
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memory T cells
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clonally expanded CD8 + effector
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expansion
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megakaryocyte-primed progenitors
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immature haematopoietic stem/progenitor cells
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megakaryopoiesis
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priming
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platelet activation
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alveolar macrophage pool
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platelets
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state
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non-classical monocyte
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COVID-19
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T
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B lymphocyte antigen receptor repertoires
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cell surface proteins
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quantification
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single cell transcriptomes
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acute inflammatory response
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lipopolysaccharide
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administered with intravenous
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healthy individuals
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non-COVID-19 severe respiratory illness
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healthy volunteers
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