362 Matching Annotations
  1. Oct 2021
    1. physicians and advanced practice clinicians in the US spent approximately 50% more time on the EHR, twice the time on order entry, and almost 3 times on in-basket work; managed triple the number of messages; and used more documentation templates and copy-paste than their non-US colleagues.2 Perhaps most striking, only the farthest outliers for time on EHR in the non-US sample, at the 99th percentile, spent the same amount of time as a US clinician at the median.2

      Radical differences between US and non-US EHR utilization.

    1. This new transparency will achieve 3 important goals. First will be a much-improved, if not ideal, representation of the EHR’s burden on providers. Second, the vendors will be seen as eager to participate in the solution to EHR-related burnout and not just the problem. Third, this will open up the possibility of cross-platform benchmarks and targets for which all health care organizations can aim.

      3 benefits of transparency between EHR vendors and healthcare providers toward understanding usage of audit logs.

    2. Ideal provider efficiency metrics might also measure efficiency of common work flows (eg, ordering an antibiotic) and isolate time spent on purely administrative tasks.

      Ideal efficiency metrics are very granular and TASK SPECIFIC.

    3. Another way 1 vendor normalizes EHR data is by adjusting the time spent per patient based on the provider’s EHR adoption. For example, if a resident writes a note and forwards it to an attending physician, the attending will likely spend considerably less time reviewing and cosigning the note than the resident did creating it. In an effort to compare the resident’s efficiency to the attending’s, each provider is assigned an adoption percentage based on the number of notes they personally authored. Based on the percentage of notes authored, a multiplier then estimates the time spent per patient if the provider authored all of their notes.

      Normalization of expected note efficiency based on # of authored notes...interesting!

    4. everything a user does, such as look at a report or enter data into a flowsheet, is assigned to a “task.” The algorithms then take each task and assign them to larger categories (eg, Orders or Clinical Review). However, because many of these tasks are vaguely named, it is very difficult to validate that they have been assigned to the correct category.

      Basic process for generating "task" types as seen in vendor access log data

    5. In order to develop usable metrics of time spent using the EHR, vendors have developed algorithms to present the data in a meaningful way. This involves decisions on how to categorize tasks, assign time to a given task, when to stop the timer for a task, and how to normalize data for comparison between users.

      Ways in which vendors have made decisions on task classification/definition

      Does this apply to signal data?

    6. Initial attempts to validate and interpret this data have proven difficult for a number of reasons, most of which involve the vendors’ proprietary algorithms which manipulate the raw data.

      need to better understand "proprietary" measures which affect interpretation of data

    7. Measuring the EHR burden on providers is hard. Quantitative models such as time–motion analysis can be effective but are time-consuming, costly, and may be limited by bias and the inability to account well for multitasking. Qualitative models can measure perceived time in the EHR, but rely on surveys given to already-burnt out providers. A more accurate and convenient model would be to utilize data from EHR vendors’ access logs to compare the documentation burden between providers.

      Current state of measuring EHR use - quantitative models expensive, qualitative models also hard.

      Lets try access/audit logs?

    8. Because the EHR can track every user keystroke, click, and mouse mile, this data can be used to compare EHR efficiency of clinicians and target low efficiency users who might benefit from additional training or clinical decision support tools. EHRs, however, are complex and implemented differently in each institution. There are no industry-standard metrics to analyze and report provider time spent in the EHR, making it impossible to compare across vendor EHRs. Furthermore, in our experience, vendor provided dashboards utilize proprietary algorithms that cannot be validated by the institutions using them.

      EHR audit logs exist, but due to EHR complexity, implementation variability, and non industry-standerdized metrics, it is hard to interpret and impossible to compare across vendors.

    9. Most providers are frustrated with the amount of time they spend in the electronic health record (EHR), especially time spent after hours and on the weekends.2 Increased burnout among physicians has been linked to the rise of the EHR and the increasing administrative burden placed on providers.3

      Foundation for EHR issues leading to burnout

    1. Options include face validity via end-user testing vs validation against an external standard, such as direct observation time-motion analysis. Manual time-motion observations are labor-intensive but currently represent the gold standard for validation.18,19,36,37 It is our hope that these core measures will be validated across different types of institutions, clinical specialties, and EHR vendors.

      Validations for EHR use metrics is hard, i.e. confirming the measurements from EHR use data actually represent reality.

    2. Not every aspect of clinical work is performed via the EHR. The time associated with phone calls, messages, family meetings, paperwork, verbal communication with colleagues, and even direct face time with patients are components of a physician’s workday that are not directly captured by EHR time stamp data.

      Much of physician work exists outside of the EHR

    3. accurate assessment of WOW requires integration of the physician’s clinic schedule with the EHR log data.

      WOW is contingent on a clear schedule of when "work" occurs.

    4. EHR use measures can likewise illuminate the impact of regulatory and compliance decisions upon clinician work.

      A global goal perhaps - "EHR use measures will be incorporated into balancing metrics for interventions"

    5. The interval without user activity that triggers a time-out from active use will impact the resulting EHR use times. Currently, this interval may vary from 5 seconds, to 90 seconds, to 30 minutes. Determining time-out intervals that best represent user activity is challenging and may vary by setting or task, and one could even argue that they should not be included at all in some calculations.

      Considering time-out interval is important

    6. EHR use measures can be used to assess the impact of new staffing models, such as advanced team-based care with in-room support.34 For example, a physician practicing with a strong, skilled team may be able to spend the majority of her time providing undivided attention to her patients, while her empowered staff enters orders, completes the billing invoice, drafts the preliminary visit note, and manages the team’s inbox. Another physician, practicing in a more “the doctor does it all” environment, performs the majority of data entry and inbox management on her own.

      Two models - "Empowered Team" and "Physician Does all"

    7. Total time on EHR (during and outside of clinic sessions) per 8 h of patient scheduled time. 

      Total EHR time per 8 hours scheduled patient time:

      Total EHR time / (Tot sched pt time/8hr)

    8. total EHR time (EHR-Time); work outside of work (WOW), often referred to as “pajama time”; time on documentation (Note-Time); time on prescriptions (Script-Time); inbox time (IB-Time); teamwork for orders (TWORD); and an aspirational measure for the amount of undivided attention patients receive from their physicians during an encounter, undivided attention (ATTN).

      7 core measures of EHR use

    9. In addition, while time alone does not capture all dimensions of work (eg, the content of work and appropriateness of tasks to different levels of training or certification), time-based metrics are relevant, interpretable, and form a foundation from which to expand upon in the future.

      Time is simple, useful, and a starting point, although with limitations.

    10. We worked with multiple stakeholders to select measures that are feasible and relevant to clinical and operational decision making. We identified time as an important unit of measure, as it is a commodity in limited supply for physicians and other health professionals.

      Tim identified as an important unit of measurement as it is a finite resource. Interesting as I wonder if time (i.e. hours worked) is associated with burnout, or rather the threshold at which this is relevant.

    11. A direct observation time-motion study in 2016 found physicians in the ambulatory setting spend half of the workday on the EHR, requiring nearly 2 hours of EHR and desk work for every 1 hour of direct clinical face time with patients.

      2hrs EHR time for every 1 hour of face-to-face patient time.

    1. Risk-enhancing factors include family history of premature ASCVD; persistently elevated LDL-C levels ≥160 mg/dL (≥4.1 mmol/L); metabolic syndrome; chronic kidney disease; history of preeclampsia or premature menopause (age <40 years); chronic inflammatory disorders (e.g., rheumatoid arthritis, psoriasis, or chronic HIV); high-risk ethnic groups (e.g., South Asian); persistent elevations of triglycerides ≥175 mg/dL (≥1.97 mmol/L); and, if measured in selected individuals, apolipoprotein B ≥130 mg/dL, high-sensitivity C-reactive protein ≥2.0 mg/L, ankle-brachial index (ABI) <0.9 and lipoprotein (a) ≥50 mg/dL or 125 nmol/L, especially at higher values of lipoprotein (a). Risk-enhancing factors may favor statin therapy in patients at 10-year risk of 5% to 7.5% (borderline risk).

      To be able to assign a value to the contributions of these disease processes, particularly earlier in life, could be a huge addition to clinical practice

    1. The authors found that although the vaccines did offer some protection against infection and onward transmission, Delta dampened that effect. A person who was fully vaccinated and then had a ‘breakthrough’ Delta infection was almost twice as likely to pass on the virus as someone who was infected with Alpha. And that was on top of the higher risk of having a breakthrough infection caused by Delta than one caused by Alpha.Unfortunately, the vaccine’s beneficial effect on Delta transmission waned to almost negligible levels over time. In people infected 2 weeks after receiving the vaccine developed by the University of Oxford and AstraZeneca, both in the UK, the chance that an unvaccinated close contact would test positive was 57%, but 3 months later, that chance rose to 67%. The latter figure is on par with the likelihood that an unvaccinated person will spread the virus.A reduction was also observed in people vaccinated with the jab made by US company Pfizer and German firm BioNTech. The risk of spreading the Delta infection soon after vaccination with that jab was 42%, but increased to 58% with time.

      Delta seems to transmit as effectively as alpha, even with vaccination

    1. An enrichment refers to a user interaction, behavior, or strategy that aims to maximize the utility of the information foraging. It can happen either between patches or within patches. Think of enrichments as an extra tool that users may use in order to forage more efficiently. The tool may be something that they already have in their pocket (such as a learned behavior) or could be built on the spot and tailored to the specific patch (in which case the user must spend time creating it). Behavior enrichments are the tools that users already have acquired and that help them extract information efficiently. These behaviors are adaptations that evolved over time and that proved to be successful in many situations in the past.

      Concepts of enrichment - ways to reduce costs?

    2. Looking up information on the web or on a webpage usually involves two types of user actions: Between-patch activities: Gathering information sources (i.e., patches) Within-patch activities: Inspecting each patch to extract information from it

      Two types of time-cost: Between patch (finding sources) an within patch (gathering from sources)

    3. What makes the scent of a webpage? When a person lands on that very page, the scent is given by the title, images, and the information that is easily visible above the fold.

      What dictates the scent of a webpage.

      But what dictates the scent of an academic paper or resource?

    4. Similarly, as a user searches for information on the web, she judges the webpages she encounters based on how well suited they are for her goal. Each source of information thus emits a “scent” — a signal that tells the forager how likely it is that it contains what she needs.

      Information "Scent" is how we are drawn to/assess value of a given information patch

    5. Specifically, people have no way of knowing in advance (1) how much information a patch contains; (2) how much time it will take them to extract that information.

      We do not know much on the other side of the decision to engage with information

    6. because they attempt to maximize the rate of gain and get as much relevant information in as little time as possible.

      Hypothetical optimization is as much information in as little time as possible.

      However, "as much information" is different from "learn as much" is different from "apply as much" is different from "meaningful impact".

    7. when users have a certain information goal, they assess the information that they can extract from any candidate source of information relative to the cost involved in extracting that information and choose one or several candidate sources so that they maximize the ratio: Rate of gain = Information value / Cost associated with obtaining that information

      Fundamental theorem of information foraging theory

      Rate of gain = information value / cost of that information

    1. If an AI model yields accurate predictions that help clinicians better treat their patients, then it may be useful even without a detailed explanation of how or why it works. It’s like the weather report, Shah says. “Do you, as a user, care how the weather is predicted, and what the causal explanation is, as long as you know a day ahead if it is going to rain and the forecast is correct?”

      Who cares about interpretability when the results are useful -> weather as an example

    1. Using magnetic bead-based absorption assays, we found that SARS-CoV-2 infections elicited a large proportion of original antigenic sin-like antibodies that bound efficiently to common seasonal human coronaviruses but poorly to SARS-CoV-2. In converse, vaccination only modestly boosted antibodies reactive to common seasonal human coronaviruses and these antibodies bound efficiently to SARS-CoV-2. Our data indicate that SARS-CoV-2 mRNA vaccinations elicit fundamentally different antibody responses compared to SARS-CoV-2 infections.

      COVID-19 vaccines provide a different, more Sars-CoV-2-specific immune response with is less protective against seasonal coronoviridae

    1. Ming Tai-Seale (mtaiseale@ucsd.edu) is a professor in the Department of Family Medicine and Public Health, University of California San Diego; director of outcomes analysis and scholarship at UC San Diego Health; and director of research at UCSD Health Sciences International, in La Jolla.Ellis C. Dillon is an assistant scientist in the Research Institute, Palo Alto Medical Foundation, in California.Yan Yang is a research economist in the Research Institute, Palo Alto Medical Foundation.Robert Nordgren is CEO of the Palo Alto Foundation Medical Group.Ruth L. Steinberg is chair of the Physician Wellbeing Committee, Palo Alto Medical Foundation.Teresa Nauenberg is a physician in the internal medicine and concierge medicine departments at the Palo Alto Medical Foundation.Tim C. Lee is a physician in the pediatrics department, Palo Alto Medical Foundation.Amy Meehan is a research associate in the Research Institute, Palo Alto Medical Foundation.Jinnan Li is a quantitative analyst in the Research Institute, Palo Alto Medical Foundation.Albert Solomon Chan is chief of digital patient experience and an investigator at Sutter Health, in Palo Alto, and an adjunct professor at the Stanford Center for Biomedical Informatics Research, Stanford School of Medicine, in California.Dominick L. Frosch is director of the Research Institute, Palo Alto Medical Foundation.

      Published by PAMF!

    2. It is necessary to recognize the different manifestations of burnout symptoms across physician genders. Female physicians have been documented to first suffer from emotional exhaustion, whereas male physicians first experience depersonalization.22 Female physicians are also more likely to experience burnout resulting from work-home conflict, whereas workload was a key predictor of burnout for male physicians.

      Different gender-specific trajectory and characteristics of burnout

    3. Health care organizations could allow messages to reach physicians’ in-baskets only during work hours, conveying the message that physicians are so highly valued that the organization wants to protect their private time.

      An interesting approach - allow the physician to go "offline" outside of work hours.

    4. Keeping up with system-generated messages can be overwhelming, particularly for internists and family physicians. Some of those messages are generated by population health management algorithms that remind physicians to perform work that might have otherwise been overlooked. These were in addition to messages coming directly from patients and from other physicians or care team members. Therefore, both perceived and realized loss of autonomy over their work schedules could leave physicians feeling defeated,20 even though some of these system-generated messages have been shown to improve certain processes of care for patients with chronic illnesses.19

      Loss of autonomy being a major driven in patient-message-driven burnout, although the message may be useful

      This is not a message problem, this is a workload volume problem.

    5. System-generated messages stood out as the largest source of messages for all specialties, especially for internal medicine (209) and family medicine (204), followed by pediatricians (102)

      System needs to be improved. The EHR is sending these messages, no providers/people.

    6. Almost half of all weekly in-basket messages came from EHR algorithms, and they were significantly associated with physicians having burnout symptoms and intending to reduce their clinical work hours.

      Physician burnout linked to in-basket overload

    1. Balancing Measures (looking at a system from different directions/dimensions) Are changes designed to improve one part of the system causing new problems in other parts of the system?

      Bringing awareness to impact of system on other areas that may be complicated by changes.

    2. Process MeasuresAre the parts/steps in the system performing as planned? Are we on track in our efforts to improve the system?

      Also could be seen as intermediate measures, surrogate measures. These focus on early outcomes that we are hoping to achieve which will ultimately lead to outcome measure progress.

    3. Three Types of Measures Use a balanced set of measures for all improvement efforts: outcomes measures, process measures, and balancing measures.

      3 types of measures in QI

    4. Outcome Measures How does the system impact the values of patients, their health and wellbeing? What are impacts on other stakeholders such as payers, employees, or the community?

      Outcome measures are measures which represent the impact of a a system on the PATIENT

  2. Sep 2021
    1. burnout may be defined by two domains, disengagement and exhaustion, or by three domains, the third being personal achievement.

      Frameworks of burnout: Disengagement and exhaustion +/- personal achievement

    2. affecting about 50% of physicians in the United States, in all stages of their medical career, in all practice settings, and in all specialties.1–3 Burned-out physicians have a twofold higher risk of leaving the institution, with turnover replacement and reduced productivity costing $4.6 billion annually in the United States.4 In addition to the financial impact, burned-out physicians have higher rates of drug and alcohol use, depression, and suicidal ideation in comparison to physicians without burnout.5–7

      Burnout prevalence and impact (turnover, morbidity/mortality)

    1. While I agree with many of the concepts & justifications given that drive an organization to form teams, however, I disagree with the notion that successfull teams can be "dynamic", or the notion of "teaming on the fly" as viable concepts. I think these ideas lack the psychological foundation of what makes a team and develops trust between the "players". Fundamental to the formation of a team is "identity". Whether it is the "Sharks" vs. the "Jets" in Westside Story or any other. There is the psychological need to belong to something. Then there is the aspect of trust. Each player needs to know their role and trust that the other will perform theirs. Trust is built on familiarity and a developed respect for each player to do their part and I might add self-sacrifice to help or pick-up the slack when your teammate falters. Failure to recognize these facts can be traced to many things. I would offer the comparrisson to modern medical teams that operate this way, however, these are the recreational equivalent of a pick-up game of basketball at the park. The participants know medicine and how to do their particular function, just as the players know how to dribble & shoot, but because they are not together all the time they don't know their tendencies. There is no trust factor that is devleoped. Their responsibility is only to their own objective, that is, do their job and hand it off to the next.

      Teaming in medicine may not be so easy

    2. Teaming is the engine of organizational learning. By now, everyone knows that organizations need to learn how to thrive in a world of continuous change. But how organizations learn is not as well understood. As discussed later in this chapter, organizations are complex entities; many are globally distributed, most encompass multiple areas of expertise, and nearly all engage in a variety of activities. What does it mean for such a complex entity to "learn"? An organization cannot engage in a learning process in any meaningful sense—not in the way an individual can. Yet, when individuals learn, this does not always create change in the ways the organization delivers products and services to customers.

      Paradox of individual vs. organizational learning, and the role of teaming as a tool to maintain organizational learning?

    3. How do you create synergy when you lack the advantages offered by the frequent drilling and practice sessions of static performance teams like those in sports and music? The answer lies in teaming. Teaming is a verb. It is a dynamic activity, not a bounded, static entity. It is largely determined by the mindset and practices of teamwork, not by the design and structures of effective teams. Teaming is teamwork on the fly. It involves coordinating and collaborating without the benefit of stable team structures, because many operations like hospitals, power plants, and military installations require a level of staffing flexibility that makes stable team composition rare.

      Teaming, this solution to dynamic team changing in settings like hospitals?

    1. In the course of that work, anomalies necessarily arise — findings that differ from expectations. Kuhn had in mind episodes such as the accidental discoveries of X-rays in the late nineteenth century and nuclear fission in the early twentieth. Often, Kuhn argued, the anomalies are brushed aside or left as problems for future research. But once enough anomalies have accumulated, and all efforts to assimilate them to the paradigm have met with frustration, the field enters a state of crisis. Resolution comes only with a revolution, and the inauguration of a new paradigm that can address the anomalies.

      The rejection of a "paradigm" occurs over time as the evidence against its "universality" becomes too overwhelming. then a "revolution" occurs in which a new paradigm evolves.

    2. To Kuhn, the concepts were incommensurable: no common measure could be found with which to relate them, because scientists, he argued, always interrogate nature through a given paradigm.

      Noncommensurate nature of old vs. new scientific paradigms. Although they appear similar on the surface, the underlying network of knowledge to develop them is fundamentally different, therefore they cannot be compared.

    3. Perhaps the most radical thrust of Kuhn's analysis, then, was that science might not be progressing toward a truer representation of the world, but might simply be moving away from previous representations. Knowledge need not be cumulative: when paradigms change, whole sets of questions and answers get dropped as irrelevant, rather than incorporated into the new era of normal science. In the closing pages of his original edition, Kuhn adopted the metaphor of Darwinian natural selection: scientific knowledge surely changes over time, but does not necessarily march towards an ultimate goal.

      The Darwinian nature of scientific knowledge. Not growing, just changing based on popularity of paradigms

    4. More than most scholars of his era, Kuhn taught historians and philosophers to view science as practice rather than syllogism.

      Science - a collection of approaches and frameworks rather than the specific individual works of science which further the body of knowledge

    1. Without making assumptions or using causal inference techniques, prognostic models should not be used for decision making that affects the treatment choice [51]. When clinicians ask, “What will the outcome of this patient be?,” they are often actually interested in the causal question “What will the outcome be on this treatment versus on another?”

      This is key. If not apply causal inference technique to eliminate confounding, you cannot infer an impact of treatments

    2. Predictive AnalysesUnlike inferential and causal analyses, predictive analyses do not seek structural knowledge about the world. Instead, they exploit correlations to predict outcomes or classify patient states at the individual level.

      What is predictive analysis?

    3. Negative control outcomes are a useful mechanism to assess susceptibility to such biases [45]. Briefly, the studies are rerun using an alternative outcome that is known to not be caused by the treatment or comparator. If the results show a significant effect, then it is likely that the results of the original study are also biased. For example, a prescription of metformin could never be causative of preprescription HbA1c levels. Therefore, if we are interested in metformin’s effect on postprescription HbA1c, we could use the preprescription value as a negative control.

      Negative control outcomes - one way to measure if observed confounders have been detected

    4. There are several challenges in using EHR data. First, EHR data are retrospective and observational, so highly prone to confounding; second, there are a variety of causal inference methods to choose from; third, it is difficult to evaluate if confounding has been addressed well enough; and fourth, causal effects vary between patients.

      Challenges to using EHR data for causal inference

    5. Inferential and Causal AnalysesClinicians are often interested in the relationship between a treatment and an outcome. In an inferential analysis, it suffices to say that the outcome and treatment change together in a statistically significant way, but that does not imply that changing the treatment would change the outcome. To perform a causal analysis, we must attempt to reduce confounding while performing inference.

      Difference between inferential (i.e. finding of association) and causal (i.e. directly effecting) an outcome -> elimination of confounding.

    6. Descriptive and Exploratory AnalysesFor complex patient populations, it is helpful to describe the population to see if interpretable patterns emerge. Traditionally, this has been done by computing summary statistics of some clinically important features across predefined subgroups of the population.

      One type of informatics consult question - just characterizing a group of patients.

      This can be extended to use unsupervised learning to identify subsets of populations with unclear clinical significance

    1. Former Herman Miller CEO Max De Pree once said, “The first responsibility of a leader is to define reality. The last is to say thank you. In between the two, the leader must become a servant.”

      Defining reality = creating predictability and constraints ,and sharing information

      Servant = allowing for job crafting, showing vulnerability

      Saying thank you = recognizing excellence

    2. managers who “express interest in and concern for team members’ success and personal well-being” outperform others in the quality and quantity of their work.

      .c2

    3. Intentionally build relationships. The brain network that oxytocin activates is evolutionarily old. This means that the trust and sociality that oxytocin enables are deeply embedded in our nature. Yet at work we often get the message that we should focus on completing tasks, not on making friends. Neuroscience experiments by my lab show that when people intentionally build social ties at work, their performance improves.

      Social interactions alone build trust. .c1

    4. When companies trust employees to choose which projects they’ll work on, people focus their energies on what they care about most. As a result, organizations like the Morning Star Company—the largest producer of tomato products in the world—have highly productive colleagues who stay with the company year after year. At Morning Star (a company I’ve worked with), people don’t even have job titles; they self-organize into work groups. Gaming software company Valve gives employees desks on wheels and encourages them to join projects that seem “interesting” and “rewarding.” But they’re still held accountable. Clear expectations are set when employees join a new group, and 360-degree evaluations are done when projects wrap up, so that individual contributions can be measured.

      Craft the job, but have expectations/guidelines and clear expectations.

    5. vague or impossible goals cause people to give up before they even start. Leaders should check in frequently to assess progress and adjust goals that are too easy or out of reach.

      poorly defined goals undermine trust. Since you can't predict well, frequent check-ins are key .c2

    6. Induce “challenge stress.” When a manager assigns a team a difficult but achievable job, the moderate stress of the task releases neurochemicals, including oxytocin and adrenocorticotropin, that intensify people’s focus and strengthen social connections.

      Challenges are beneficial if achievable. .c1

    7. I identified eight management behaviors that foster trust.

      1) Recognize Excellence 2) Induce “challenge stress.” 3) Give people discretion in how they do their work. 4) Enable job crafting. 5) Share information broadly. 6) Intentionally build relationships. 7) Facilitate whole person growth. 8) Show vulnerability.

    8. why trust varies across individuals and situations. For example, high stress is a potent oxytocin inhibitor. (Most people intuitively know this: When they are stressed out, they do not interact with others effectively.) We also discovered that oxytocin increases a person’s empathy, a useful trait for social creatures trying to work together.

      Thinking about environmental factors that modulate oxytocin release, STRESS = inhibitor.

    9. Comparing participants who received a real dose with those who received a placebo, we found that giving people 24 IU of synthetic oxytocin more than doubled the amount of money they sent to a stranger. Using a variety of psychological tests, we showed that those receiving oxytocin remained cognitively intact. We also found that they did not take excessive risks in a gambling task, so the increase in trust was not due to neural disinhibition. Oxytocin appeared to do just one thing—reduce the fear of trusting a stranger.

      Administration of oxytocin induced trust!

    10. We found that the more money people received (denoting greater trust on the part of senders), the more oxytocin their brains produced. And the amount of oxytocin recipients produced predicted how trustworthy—that is, how likely to share the money—they would be.

      Result -> more oxytocin = more trustworthy

      .c2

    11. To measure oxytocin levels during the exchange, my colleagues and I developed a protocol to draw blood from people’s arms before and immediately after they made decisions to trust others (if they were senders) or to be trustworthy (if they were receivers).

      Protocol for measuring oxytocin + task

      .c1

    12. I knew that in rodents a brain chemical called oxytocin had been shown to signal that another animal was safe to approach.

      Oxytocin as a "safety" marker -> "safe to approach"

      This maps trust onto a concrete biological phenomenon

    13. In my research I’ve found that building a culture of trust is what makes a meaningful difference. Employees in high-trust organizations are more productive, have more energy at work, collaborate better with their colleagues, and stay with their employers longer than people working at low-trust companies. They also suffer less chronic stress and are happier with their lives, and these factors fuel stronger performance.

      Trust as the objective of leadership.

  3. Aug 2021
    1. The AI in Healthcare Specialization can serve as the foundation of anyone’s health AI education.

      Possibly useful, but expensive. Should doin a down month

    2. Jeremy Howard’s fast.ai course was my personal favorite and is the ideal resource for anyone with a strong technical background who knows even a little bit of coding

      Good option for AI learning

  4. Jul 2021
  5. www.journalofhospitalmedicine.com www.journalofhospitalmedicine.com
  6. Jun 2021
    1. results are often not available for several weeks, while treatment decisions may need to be made before the specific serologic profile is known.

      Not a reason to change management, clinical suspicion key

    2. dermatomyositis (DM) classically present with symmetric muscle weakness, elevated muscle enzymes, and characteristic cutaneous findings

      DM = weakness + cutaneous findings

  7. May 2021
    1. One crucial difference, however, is the need for added emphasis on ventilation because the tiniest suspended particles can remain airborne for hours, and these constitute an important route of transmission.

      If we are staying 3-6ft away from people and wearing masks, when you add ventilation to the equation, the result is low concentration, low-risk spread of diseases

    2. Essentially, if you can inhale particles—regardless of their size or name—you are breathing in aerosols. Although this can happen at long range, it is more likely when close to someone, as the aerosols between two people are much more concentrated at short range

      Proximity matters, but it is a continuum and concentration is KEY (concentration is WHY proximity matters)

    1. Our systematic review found that poor handover is associated with multiple potential hazards. No single tool arises as best to evaluate the handover process. There is little empirical evidence delineating what constitutes best handover practices.

      The core takeaways.

    2. there is a limited amount of good-quality research on handover. Failure to show effects may be that the included studies are of little quality and yield heterogeneous results.

      No good trials, probably because of poor study design

    3. principal teaching methods are role-playing and simulation, which are better received by learners than didactic sessions

      best practices for teaching about handover

    4. Discussion

      Mentions 3 specific categories:

      1. Poor handover is associated with various surrogates for worse patient care, and there were common themes in what defines "poor handover"
      2. There is no ideally situated/effective tool to measure effectiveness of handover - if you can't measure its effectiveness, how can you prove improvement?
      3. Third (and kind of THEREFORE) there is no clear "best practice"
    5. Lack of active listening, lack of attention or divided attention of the receiving healthcare professional(s), workload and lack of time were the leading causes of poor handover

      Why hand-off fails: interruption, not full attention

    1. Create specific moments to help the incoming party prepare for the handoff, thus shaping his or her mental models of the patients.

      Pre-rounding/chart biopsy before a hand-off -> even with a rudimentary model of a patient in place, the ability to receive and ask more intelligent/targeted questions is even more powerful

    2. Without this question to the outgoing party, there may be an incomplete understanding about the patient. Sometimes, a question can even be an active formulation of an alternative hypothesis about the patient's fundamental or likely trajectory.

      Active engagement in the information exchange process through questions needs to be encouraged.

    3. Encourage and teach the outgoing party to take the perspective of the one coming on [47].

      Yes! but a prerequisite to this is that the outgoing party must know what the perspective of in incoming party is, which may not be possible if they have never cross-covered.

    4. This empirical evidence actually agrees with qualitative research that suggests that residents perceive standardized tools for handoff s as being possibly detrimental [46].

      Moral of the story: handoff tools need to support a complex cognitive process rather than trying to make that complex cognitive process fit a specific checklist.

    1. We did not evaluate the impact of the content overlap on sign-out qualit

      This is what I find so interesting about the future use of this study. Okay, so there is full overlap here - but is it useful? are we stressing this piece of information in BOTH streams of sign-out, but it actually isn't useful??

    2. No overlap: Written documentation content was not present at all in the verbal communication content (ie there was no match).

      This category is where a flexible, editable "living document" for sign-out combined with a collaborative sign-out approach is really key to thread the needle through what information needs to exist in what space for effective signout. Collaborative sing-out becomes the glue that holds this together

    3. Clinical content framework

      Very interesting way of categorizing/captures in a mutually exclusive and collectively exhaustive way what is included in sign-out

    4. This encrypted, Microsoft Word-based sign-out document was maintained external to the institution’s Electronic Health Record (EHR) and was organized in a standardized problem-based format with the following information: patient identifying information [name, date of birth, medical record number (MRN), room number, allergies, code and contacts], history of presenting illness (HPI), active problems, medications, and tasks to-do. An example sign-out document is provided in the Supplementary Figure S1.

      In reviewing the supplemental materials, this is an extremely rudimentary tool, a table with minimal formatting and contains: core stable information (name, room, age/sex, MRN, Code, allergies?), oneliner and events, a manually entered list of medications, extremely brief contingencies, tasks, and situational awareness

    5. Resident sign-outs occurred at 5 pm daily, and involved the verbal exchange of information from the outgoing to the incoming resident.

      Scheduled, defined sing-out time

    6. Their comparative evaluation showed that the written documentation served as a cognitive aid for sign-out communication and reasoning.

      What is the role of sign-out documentation? It is for SUPPORTING the verbal exchange of information, not to supplant the information available in the EHR. this is KEY.

    7. no empirically validated content frameworks that can used to evaluate the overlap between written sign-out documentation and verbal communication.

      Their question: What is in verbal sign-out, what is in written sign-out, what is the overlap?

    8. In other words, only a few studies have evaluated both written documentation and verbal communication for comprehensively characterizing the nature of content and structure of resident sign-outs.

      Dearth of studies which effectively evaluate or characterize both written and verbal signout + provide evidence-based recommendations OR evidence-proven systems to revise sign-out practices.

    9. information discrepancies, declined rapidly over a 6-h period after sign-out, with the number of information discrepancies increasing over time.

      It took ONLY SIX HOURS for information to decline and begin to have meaningful discrepancies. Fascinating. Majority is medications, which makes sense.

      More likely to decay -> benefits from pointing to EHR or more vague inclusion. What is the highest level of information needed to convey the desired message to the cross cover provider? (i.e. on anticoag >> on Lovenox SubQ BID if just trying to convey that patient is at higher risk of bleeding)

    10. verbal sign-out communication, and that of written and electronic sign-out documentation

      two-component model of sign-out (written, verbal)

    1. The bundled intervention demonstrated increased patient handoff and health resource utilization compared with usual handoff practices.

      So hard to know what these mean. Also, since the proportion of patients signed out was no different between groups, it makes you wonder if just more patients need to be signed out because there were more patients to sign out in the intervention group. Nothing captures the "efficiency" of the signout process to suggest that "more patients being signed out" is a surrogate for "more effective sign-out meaning more effective transfer of information for as many or more patients with no associated costs to resident"

    2. handoff information following the widely adopted SIGNOUT? mnemonic (Sick or do not resuscitate, Identifying data, General hospital course, New events of the day, overall health status, Upcoming possibilities with plan, Tasks to complete, ?Questions)

      Pneumonic for should be included in signout, kind of cute. Again, just another example of a checklist that is likely better accomplished as an integrated template within the sign-out tool.

    3. The iHAND criteria showed a moderately significant correlation with requiring assessment overnight

      An interesting effort to validate the iHAND frameowkr as being meaningful in the context of sign-out, i.e. specifically asking and trying to answer the question of "which patients will need attention overnight" -> our goal is to sign-out ONLY patients with a likely need for overnight assessment or interaction from cross-covering provider.

    4. type of patient to handoff, trainees were instructed to handoff all patients who had any of: (i) investigations pending, (H) currently located in a high acuity unit, (A) abnormal vital signs in the preceding 24 hours, (N) newly admitted in the last 24 hours, and (D) dying.

      iHAND framework which allows for filtering and categorization of patients that need to be signed out.

    5. 45-minute training and education session on the importance and evidence for patient handoff, standardization of type of patient and information to handoff as well designating a fixed time (17:30–18:00) and dedicated quiet location for face-to-face handoff

      Two interventions: 1) Education around handoff (including their iHAND framework) 2) Dedicated quiet space + time for handoff

    6. At large institutions with high volumes of inpatients, handoff on all patients is not feasible, thereby requiring daytime physicians to prioritize a smaller subset of patients to convey potential issues on.

      interesting that this is identified as an issue AND that there is some implied benefit of handing off more patients. Our cognitive capacity is a more important rate limiting step than "time" to get more patients signed out. unsurprising that this intervention had no impact on outcomes.

    1. A checklist of necessary information can help teach others new to the handoff about the process and serve as a monitoring tool in evaluating the content transferred.

      Checklist needs to be seen as a vague term, defined as something like: An intervention/tool that adds a clear framework to the signout process and provides a consistent guide for individuals to be reminded to include all components

      It does not necessary need to be a list with checkboxes. It can be a standardized sign-out template that hints/encourages all necessary information, seamlessly integrated into a workflow.

    2. “What are the main content pieces of a handoff in your discipline?”

      In the case of internal medicine sign-out, the standardization of content likely lands in broader categories to facilitate a framework that can be applied to a wide range of patients

    3. communication of information (content) that can take place through different modalities, which can include a written or verbal component.

      Two core frameworks here:

      1. Hand-off is an exercise in communicating information (synonymous with learning/teaching, I think)
      2. It is organized into two different mediums: verbal and written -> one must learn the effective approach to VERBAL sign-out and WRITTEN sign-out, how they overlap, how they interact, and what the role of each is
    1. often include more information as the hospitalization progresses, but that this information may not be helpful.

      Skeletons! persistent pruning is necessary.

    2. Table 1. Information Abstracted From Written Sign‐out Entries

      Provides an excellent framework for educational intervention AND a way to deliver feedback (particularly the "vague language" and "conflicting info" parts)

    3. Rationale for decisions

      I think this is so valid - don't just say "Stopped heparin" say "stopped heparin because of persistent epistaxis" - we do this naturally, but being intentional about this connection is helpful

    4. 11 elements that should be present in a high‐quality written sign‐out and 2 (vague language and confusing/conflicting language) that should not be present (Table 1).

      Helpful categorization, table matches our experience at UCSF

    5. 2 sites did not have EHR‐assisted sign‐out tools at the time of this study, and providers typed all information in Microsoft Excel or Word (Microsoft Corp., Redmond, WA)

      Interesting how clinical sites used word or excel, never paper-only

    1. Given that integration is the goal, many students of color who seek ‘safe’ race discussions in public rarely find them, having to settle for the reality that most pedagogical situations involving race are violent to them.

      Safe is...never? not currently? possible for POC

    2. Our main criticism of safe space is that it is laced with a narcissism that designates safety for individuals in already dominant positions of power, which is not safe at all but perpetuates a systematic relation of violence.

      What is the definition of "safety"? what is the definition of "violence"? descriptive terminology needs to be clear.

    3. critical race pedagogy is inherently risky, uncomfortable, and fundamentally unsafe (Lynn 1999Lynn, M. 1999. Toward a critical race pedagogy: A research note. Urban Education, 33(5): 606–26.  [Crossref], [Web of Science ®], [Google Scholar]), particularly for whites. This does not equate with creating a hostile situation but to acknowledges that pedagogies that tackle racial power will be most uncomfortable for those who benefit from that power.

      I like this way of expressing that racial discourse needs to be uncomfortable, but that does not mean hostile

    1. “so what is it about this ethnicity that makes them that way?” And they [the lecturer] point to genetics. And I’m like, “Well, we’re 99.9% alike. So, is it genetics that’s making the change?” And then that’s when me and the lecturer are at a standstill. [Then the lecturer says] “It’s not genetics, but I don’t really know the reason. So, let’s move on.”

      This is disturbing, but also complex to unpack. There IS genetic variability that is meaningful. Race is a bad surrogate for that meaningfulness. Ancestry may be better. Genetic analysis and GWAS or proteomics are the most powerful?

    2. I raised my hand and answered the question. She [the instructor] shot in front of the whole class and said, “[I 3E], can we get someone else’s input. I don’t need your input. I need an educated answer; we don’t need your guess.”

      This just sounds like a really bad professor, again though, how can you know if there was a microaggression? If we are made more aware of microaggressions do we begin to see things as microaggressions based on race, when they actually aren't? does this perpetuate feelings of racial inferiority more than it might otherwise? I'm not sure.

    3. I became very aware of how different I was from the general student body.

      Are you different? Or do you feel different (because you look different) but really aren't in a meaningful way? If you ARE different in some fundamental way (regardless of why) - is it not OKAY to stand out and be different as long as you are accepted for those differences?

    4. I think there is isolation because I feel excluded in conversations. I prefer to not be in that position, so I spend all my time by myself.

      Isolation because of how hard it is to face the frequent reminder of being different

    5. black people are better prepared than white people to cope with blatant prejudice but are particularly vulnerable to cognitive impairment resulting from exposure to ambiguous prejudice (a level of prejudice that white persons may not even register).

      Interesting to think about the greater challenge faced by an ambiguous/subconscious bias rather than overt, obvious aggressions

    1. In some important professions, such as physics and engineering, Asian Americans are overrepresented and African Americans underrepresented. We presumably get better research because of this. This may or may not outweigh the inequity of unequal group representation. That is a social decision.

      This is a great article, but this statement irks me. "We presumably get better research out of this" - I do not think we can presume that. While a stopwatch may make a truer meritocracy (although one can argue that environment still plays a part in this), certainly there is a tremendous amount of environmental factors involved in what drives overrepresentation of certain racial or ethnic groups in "high-achieving" professions like physics or engineering.

  8. Apr 2021
    1. U.S. health care system currently suffers from a dearth of frontline clinical leaders precisely because our educational system does not consistently and explicitly prioritize leadership development.

      This is so similar to education - Are all doctors predisposed to or interested in being educators (leaders)?

      How can we all be: Physicians - masters of clinical assessment and knowledge Teachers - able to educate and mentor our patients + learners Leaders/Managers - navigate and guide change, manage work, etc.

      Add +Skilled with technology - informatics

    2. Providers, educators, and administrators need to dispel the myth that clinical and managerial responsibilities are inherently at odds with one another.

      Again, is this about DISPELLING A MYTH? or just REVISING THE DEFINITION OF PHYSICIAN WORK

    3. how to manage relationships and negotiate with colleagues and patients

      We learn all about doing this with patients, and it translates to teams, colleagues

    4. ACGME's Practice-based Learning and Improvement competency (which includes engaging in “constant self-evaluation”; participating in patient, family, student, and health care professional education; and leading quality improvement efforts) is addressed in leadership training through efforts to build self-understanding, the capacity for self-reflection, negotiation skills, and the abilities to learn from experience, create personal development goals, and manage interpersonal relationships.

      This makes me wonder if our training DOES include this content but just needs to be labeled as such. A thread rather than a competency

    5. First, leadership development must become an explicit goal of residency training.

      This is already true, and I think is perhaps the root cause of discomfort - "You are a leader" or "You need to be a leader" - but nothing to help that happen.

    6. Harvard Business School. MBA students explore their leadership motivations and capabilities through an iterative process that includes three critical parts: experience, reflection, and feedback.

      A lot like Kolbs

    7. CCL asserts that successful leadership development programs include three components: Assessments of trainees' leadership skills and development over time; content that Challenges participants to operate outside of their comfort zones—which is critical for skill development—and to take personal responsibility for their leadership development; and Support for learners through high-quality teaching, constructive feedback, and postcourse coaching (the “ACS Model”)

      Assessment - cultivate understanding Challenge - stimulate growth Support - provide tools to grow

    8. Moreover, many providers perceive an inherent tension between managing care and providing it. This wariness of managerial work is deeply rooted in the culture of medicine and medical education.

      Is this true? Or do we just see managerial work as not what we were trained to do, therefore not in our scope of practice.

    9. Most physicians value autonomy and often view practice interventions—including efforts to increase collaboration across providers—as a threat to their independence.

      Is this true?

    10. three different types of clinical leaders have been identified: institutional leaders (e.g., CEOs), service leaders (e.g., department chairs or research directors), and frontline leaders (e.g., those who work at the interface of patient care).

      So interesting...What about leading your patients?

  9. Oct 2020
    1. we note that many of the lectures were also recorded so they would be available to students, both present and absent, for later viewing.

      Magnification of social faux pas in VDME with recordings

    2. allowed participants to passively watch lecturers or their fellow students on the screen, as a viewer might watch a television.

      the "observer role"

    3. seen at local and satellite sites from multiple angles and it is anxious making. In addition, I know I was being taped. Not to mention that there are people in the control room ensuring that technologically all goes okay. I felt like saying, “Does the camera add x number of pounds?” Everyone is watching and I felt super conscious.

      This really is no different than it would be in person other than the magnification and recording

    4. placed a series of cameras throughout the classroom, a gooseneck microphone at each lecture podium, small dome-shaped microphones at student desks, and a collection of speakers in the ceiling.

      created an environment clearly conducive to this mode of teaching. also with technology that would facilitate individual student agency

  10. Mar 2020