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Disrupting mitochondrial dynamics attenuates ferroptosis and chemotoxicity via upregulating NRF2-mediated FSP1 expression

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1. scibot 04 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116234
  
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High matrix stiffness triggers testosterone decline in aging males by disrupting stem Leydig cell pool homeostasis

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  DOI: 10.1016/j.celrep.2025.116207
  
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Aug 2025
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BPS Publications

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1. scibot 27 Aug 2025
  
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  DOI: 10.1111/bph.70175
  
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The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition

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  DOI: 10.1016/j.molcel.2025.07.015
  
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The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity

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1. scibot 20 Aug 2025
  
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  DOI: 10.1177/03000605251365844
  
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A CD147-targeted small-molecule inhibitor potentiates gemcitabine efficacy by triggering ferroptosis in pancreatic ductal adenocarcinoma

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  DOI: 10.1016/j.xcrm.2025.102292
  
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TRIM6 ablation reverses ICB resistance in MSS gastric cancer by unleashing cGAS-STING-dependent antitumor immunity

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1. scibot 19 Aug 2025
  
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  DOI: 10.1186/s13046-025-03513-5
  
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The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of renal cell carcinomas with tumor thrombi

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  DOI: 10.1016/j.devcel.2025.07.010
  
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Extrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1-Lig3-PARylation complex

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1. scibot 06 Aug 2025
  
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  RRID:AB_10015666
  
  DOI: 10.1016/j.molcel.2025.07.007
  
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Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression

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1. scibot 05 Aug 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-3525
  
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Activation of Lysosomal Retrograde Transport Triggers TPC1-IP3R1 Ca2+ Crosstalk at Lysosome-ER MCSs Leading to Lethal Depleting of ER Calcium

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1. scibot 01 Aug 2025
  
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  RRID: AB_2107436
  
  DOI: 10.1002/advs.202415313
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202415313
Jul 2025
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BRD9 inhibition overcomes oncolytic virus therapy resistance in glioblastoma

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1. scibot 31 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102258
  
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RACK7 senses and fine-tunes enhancer activity

1
1. scibot 31 Jul 2025
  
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  RRID:AB_2107436
  
  DOI: 10.1016/j.isci.2025.113083
  
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Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis

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1. scibot 30 Jul 2025
  
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  DOI: 10.4103/NRR.NRR-D-24-00302
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12296486/
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Sophoridine inhibits proliferation and migration by targeting PIM1 in breast cancer

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1. scibot 29 Jul 2025
  
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  RRID:AB_2107436
  
  DOI: 10.1080/13880209.2025.2537123
  
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tandfonline.com/doi/abs/10.1080/13880209.2025.2537123
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RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer

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1. scibot 29 Jul 2025
  
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  DOI: 10.1038/s41388-025-03502-0
  
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nature.com/articles/s41388-025-03502-0
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Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers

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1. scibot 29 Jul 2025
  
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  RRID:AB_2107436
  
  DOI: 10.1016/j.xcrm.2025.102253
  
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Novel Aptamer-Drug Conjugate for Targeted Therapy in Triple-Negative Breast Cancer

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1. scibot 25 Jul 2025
  
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  DOI: 10.1021/acs.jmedchem.5c00492
  
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52.53.155.43 52.53.155.43

1-s2.0-S2589004225014269-main-html.html

1
1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113165
  
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Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing

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1. scibot 17 Jul 2025
  
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  DOI: 10.1186/s12951-025-03548-y
  
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1-s2.0-S2589004225013823-main-html.html

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  DOI: 10.1016/j.isci.2025.113121
  
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Identification of osteoblastic autophagy-related genes for predicting diagnostic markers in osteoarthritis

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  DOI: 10.1016/j.isci.2024.110130
  
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IFNγ augments TKI efficacy by alleviating protein unfolding stress to promote GSDME-mediated pyroptosis in hepatocellular carcinoma

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1. scibot 15 Jul 2025
  
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  DOI: 10.1038/s41419-025-07839-y
  
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1-s2.0-S2589004225013446-main-html.html

1
1. scibot 15 Jul 2025
  
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  DOI: 10.1016
  
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52.53.155.43/3a940a222b37943f01bb89b56d8fe0b40f820eb6/1-s2.0-S2589004225013446-main-html.html
journals.physiology.org journals.physiology.org

3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/ROCK pathway

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1. scibot 09 Jul 2025
  
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  RRID:AB_2107436
  
  DOI: 10.1152/ajpcell.00014.2020
  
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Inhibition of the upregulated phosphodiesterase 4D isoforms improves SERCA2a function in diabetic cardiomyopathy

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  DOI: 10.1111/bph.17411
  
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52.53.155.43 52.53.155.43

1-s2.0-S2589004225013343-main-html.html

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1. scibot 08 Jul 2025
  
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  RRID:AB_2107436
  
  DOI: 10.1016/j.isci.2025.113073
  
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GLDC attenuates liver ischemia-reperfusion injury by inhibiting macrophage recruitment and activation via PTBP1/P2RY6

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  DOI: 10.1016/j.cellsig.2025.111976
  
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sciencedirect.com/science/article/pii/S0898656825003912
bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

Brain miR-137 governs growth and development via GH/IGF-1 signaling

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  DOI: 10.1186/s12915-025-02306-8
  
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TM9SF3 is a Golgi-resident ATG8-binding protein essential for Golgi-selective autophagy

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  DOI: 10.1016/j.devcel.2025.06.017
  
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The planar cell polarity (PCP) protein Fat 1 in Sertoli cell function

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  DOI: 10.1210/endocr/bqae041
  
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AGPAT3 deficiency impairs adipocyte differentiation and leads to a lean phenotype in mice

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  DOI: 10.1152/ajpendo.00012.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11390115/
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Gut microbiota-bile acid crosstalk contributes to calcium oxalate nephropathy through Hsp90α-mediated ferroptosis

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  RRID:AB_2107436
  
  DOI: 10.1016/j.celrep.2025.115936
  
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sciencedirect.com/science/article/pii/S2211124725007077
Jun 2025
www.cell.com www.cell.com

BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival

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1. scibot 28 Jun 2025
  
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  RRID:AB_2107436
  
  DOI: 10.1016/j.molcel.2025.05.035
  
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cell.com/molecular-cell/fulltext/S1097-2765(25)00499-X
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A repeatedly evolved mutation in Cryptochrome-1 of subterranean animals alters behavioral and molecular circadian rhythms

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Cingulin is an RNA-binding protein promoting pancreatic cancer through enhancing importin 7-mediated phospho-ERK nuclear translocation

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RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation

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  DOI: 10.1016/j.cmet.2025.05.014
  
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DTL dose-dependent control of sex-dimorphic ferroptosis in liver ischemia reperfusion injury

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Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway

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  DOI: 10.1007/s12017-025-08863-z
  
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Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation

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PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer

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  DOI: 10.1038/s41388-025-03468-z
  
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Manipulation of host-plant preference by virus-induced changes to its insect vector’s olfactory system

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  DOI: 10.1016/j.cub.2025.05.064
  
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1-s2.0-S2589004225011927-main-html.html

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  RRID:AB_2107416
  
  DOI: 10.1016/j.isci.2025.112931
  
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Critical impact of lysine 136 in TDP-43 phase separation, compartmentalization, and aggregation in living vertebrates

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  DOI: 10.1016/j.isci.2025.112761
  
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Nociceptor-derived CGRP enhances dermal type I conventional dendritic cell function to drive autoreactive CD8+ T cell responses in vitiligo

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Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice

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ENPP1 governs the metabolic regulation of effector T cells in autoimmunity by detecting cytosolic mitochondrial DNA

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  DOI: 10.1016/j.celrep.2025.115851
  
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RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsis

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RNA m6A dynamics promote transcription and RNA stability of bivalent genes during iPSC-induced generation of human lung progenitors

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The effect of G-quadruplexes on TDP43 condensation, distribution, and toxicity

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The RNA-stability-independent role of the RNA m6A reader YTHDF2 in promoting protein translation to confer tumor chemotherapy resistance

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Dectin-1 facilitates lung fungal-mediated pulmonary fibrosis

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Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation

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Glutamate transporter SLC1A6 promotes resistance to immunotherapy in cancer

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PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity

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Astrocyte induction of disease-associated microglia is suppressed by acute exposure to fAD neurons in human iPSC triple cultures

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Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity

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SPT6 regulates H3K14Ac deposition in mouse embryonic stem cells

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Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia

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CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models

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Mediator regulates transcriptional termination through crosstalk with pre-mRNA 3′ end processing factors

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Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

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Opsin3 regulates cell proliferation, migration, and apoptosis in lung adenocarcinoma via GPX3 pathway

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  DOI: 10.1186/s40001-025-02581-9
  
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Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1

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GuBenPeiYuan Formula Inhibits Lung Cancer Metastasis by Suppressing Myeloid-Derived Suppressor Cells and Related Immune Cells

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Tong-Qiao-Huo-Xue Decoction mitigates post-stroke inflammatory response via suppression of the FIB-NLRP3 signaling pathway

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  DOI: 10.1007/s11011-025-01633-7
  
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A novel synthesised STAT3 inhibitor exerts potent anti-tumour activity by inducing lysosome-dependent cell death

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  DOI: 10.1111/bph.70071
  
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Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain

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  DOI: 10.1016/j.cell.2025.04.038
  
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Heterogeneity of late endosome/lysosomes shown by multiplexed DNA-PAINT imaging

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CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density

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1-s2.0-S258900422500882X-main-html.html

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Rab32 protects mitochondrial function by anchoring Fancd2 and mediates the protective effect of penehyclidine hydrochloride against myocardial ischemia-reperfusion injury

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Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity

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HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma

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A retinoic acid:YAP1 signaling axis controls atrial lineage commitment

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Mechanobiological mechanism of cyclic stretch-induced cell columnarization

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Condensation-dependent multivalent interactions of EB1 and CENP-R regulate chromosome oscillations in mitosis

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Knockdown NEK7 stimulates anti-tumor immune responses by NLRP3/PD-L1 signaling in esophageal cancer

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APP β-CTF triggers cell-autonomous synaptic toxicity independent of Aβ

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ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition

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Protein O-GlcNAcylation and hexokinase mitochondrial dissociation drive heart failure with preserved ejection fraction

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A competition network connects Rab5 and Rab11 GTPases at the surface of endocytic structures

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A Novel Mechanism of the p53 Isoform Δ40p53α in Regulating Collagen III Expression in TGFβ1-Induced LX-2 Human Hepatic Stellate Cells

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Integrating bulk, single-cell, and spatial transcriptomics to identify and functionally validate novel targets to enhance immunotherapy in NSCLC

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  DOI: 10.1038/s41698-025-00893-x
  
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Inflammation-responsive biomimetic nanoparticles with epigallocatechin-3-gallate for acute lung injury therapy via autophagy enhancement

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BPS Publications

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Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity

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1-s2.0-S0016508525005426-main-html.html

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1-s2.0-S2589004225005346-main-html.html

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Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution

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Dexmedetomidine alleviates the pro-tumor activity of perioperative stress in tumor-bearing mice: an alternative approach of psycho-physiological intervention

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Discovery of targeting USP10-mediated proline metabolism arrangement to inhibit hepatocellular carcinoma progression

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1-s2.0-S2589004225005577-main-html.html

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ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation

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BET inhibitor in combination with BCG vaccine enhances antitumor efficacy and orchestrates T cell reprogramming for melanoma

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1-s2.0-S2589004225004316-main (1)-html.html

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FLOT1 Is a Novel Serum Biomarker of Ovarian Cancer Targeted by N6-methyladenosine Modification Inhibition

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7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death

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ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity

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Intestinal microbiota affects the progression of colorectal cancer by participating in the host intestinal arginine catabolism

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Feb 2025
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PDF-html.html

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Designer polyQ fusion proteins sequester USP7/HDM2 for modulating P53 functionality

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ROS-responsive nanoparticles with selenomethionine for ferroptosis modulation in abdominal aortic aneurysm

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Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism

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Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance

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GPNMB and ATP6V1A interact to mediate microglia phagocytosis of multiple types of pathological particles

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USP14 modulates stem-like properties, tumorigenicity, and radiotherapy resistance in glioblastoma stem cells through stabilization of MST4-phosphorylated ALKBH5

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Role of HNF4A-AS1/HNRNPC-mediated HNF4A Ubiquitination Protection against Ritonavir-induced Hepatotoxicity

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SIK2 and SIK3 differentially regulate mouse granulosa cell response to exogenous gonadotropins in vivo

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Bat-infecting merbecovirus HKU5-CoV lineage 2 can use human ACE2 as a cell entry receptor

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Downregulation of BASP1 promotes temozolomide resistance in gliomas via epigenetic activation of the FBXO32/NF-κB/MGMT axis

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Metabolic phenotypes and fatty acid profiles associated with histopathology of primary aldosteronism

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Synonymous mutations promote tumorigenesis by disrupting m6A-dependent mRNA metabolism

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Peptide PDHPS1 inhibits ovarian cancer growth through disrupting YAP signaling

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Targeting SHCBP1 Inhibits Tumor Progression by Restoring Ciliogenesis in Ductal Carcinoma

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TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma

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Inhibition of SCFKDM2A/USP22-dependent nuclear β-catenin ubiquitylation mediates cerebral ischemic tolerance

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PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells

1
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1-s2.0-S2589004225002330-main-html.html

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ovarianresearch.biomedcentral.com ovarianresearch.biomedcentral.com

Dynamic and functional analyses of exosomal miRNAs regulating cellular microenvironment of ovarian cancer cells

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1-s2.0-S258900422500224X-main-html.html

1
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STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma

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The coagulation and tumor system are directly linked through the proteolysis and activation of epidermal growth factor receptor by thrombin

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  DOI: 10.1038/s41388-025-03296-1
  
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2. scibot 06 Feb 2025
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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Mechano-electrical transduction components TMC1-CIB2 undergo a Ca2+-induced conformational change linked to hearing loss

7
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  DOI: 10.1016/j.devcel.2025.01.004
  
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2. scibot 06 Feb 2025
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2107436
3. scibot 05 Feb 2025
  
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  RRID:AB_2107436
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2107436
4. scibot 04 Feb 2025
  
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  RRID:AB_2107436
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2107436
5. scibot 03 Feb 2025
  
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  RRID:AB_2107436
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2107436
6. scibot 02 Feb 2025
  
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  RRID:AB_2107436
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2107436
7. scibot 01 Feb 2025
  
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  RRID:AB_2107436
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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Meteorin-like alleviates hepatic steatosis by regulating hepatic triglyceride secretion and fatty acid oxidation

1
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Impaired inflammatory resolution with severe SARS-CoV-2 infection in leptin knock out obese hamster

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The mitochondrial DNAJC co-chaperone TCAIM reduces α-ketoglutarate dehydrogenase protein levels to regulate metabolism

1
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  DOI: 10.1016/j.molcel.2025.01.006
  
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Mechano-electrical transduction components TMC1-CIB2 undergo a Ca2+-induced conformational change linked to hearing loss

1
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson’s disease

1
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  DOI: 10.4103/NRR.NRR-D-23-01684
  
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Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation

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  DOI: 10.1016/j.cell.2024.12.009
  
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Tubulointerstitial nephritis antigen-like 1 promotes the progression of liver fibrosis after HCV eradication with direct-acting antivirals

1
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  DOI: 10.7150/ijbs.103305
  
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Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy

1
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  DOI: 10.1016/j.celrep.2024.115205
  
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Transketolase attenuates the chemotherapy sensitivity of glioma cells by modulating R-loop formation

1
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Downregulation of HSP47 Triggers ER Stress-mediated Apoptosis of Hypertrophic Chondrocytes Contributing to T-2 toxin-induced Cartilage Damage

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Ca2+/calmodulin-dependent protein kinase II β decodes ER Ca2+ transients to trigger autophagosome formation

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Targeting ROR2 homooligomerization disrupts ROR2-dependent signaling and suppresses stem-like cell properties of human breast adenocarcinoma

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N6-methyladenosine in 28S rRNA promotes oncogenic mRNA translation and tyrosine catabolism

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IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth

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The human zinc-binding cysteine proteome

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Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1

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Phospholipase D Family Member 4 Regulates Microglial Phagocytosis and Remyelination via the AKT Pathway in a Cuprizone‐Induced Multiple Sclerosis Mouse Model

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ANLN promotes head and neck squamous cell carcinoma progression by upregulating PD-L1 via the ERK-MAPK pathway-html.html

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N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer

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Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy

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Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus

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Energetics of cholesterol perception and translocation in the human Smoothened receptor

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  DOI: 10.1101/2024.11.25.625241
  
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Genetic and microenvironmental evolution of colorectal liver metastases under chemotherapy

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Chemical activation of mitochondrial ClpP to modulate energy metabolism of CD4+ T cell for inflammatory bowel diseases treatment

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p53 induces circFRMD4A to suppress cancer development through glycolytic reprogramming and cuproptosis

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  DOI: 10.1016/j.molcel.2024.11.013
  
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Structure-guided development of selective caseinolytic protease P agonists as antistaphylococcal agents

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The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo

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Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma

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Human genetics identify convergent signals in mitochondrial LACTB-mediated lipid metabolism in cardiovascular-kidney-metabolic syndrome

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Opposing roles for AMPK in regulating distinct mitophagy pathways

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Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function

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SIRT3 differentially regulates lysine benzoylation from SIRT2 in mammalian cells

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Genome-wide mapping of native co-localized G4s and R-loops in living cells

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Reduced mesencephalic astrocyte-derived neurotrophic factor ... : Neural Regeneration Research

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  DOI: 10.4103/NRR.NRR-D-23-01666
  
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Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation

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Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms

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  DOI: 10.26508/lsa.202402829
  
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Oct 2024
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P16INK4A drives RB1 degradation by UTP14A-catalyzed K810 ubiquitination

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NAPRT silencing in FH-deficient renal cell carcinoma confers therapeutic vulnerabilities via NAD+ depletion

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  DOI: 10.1158/1541-7786.MCR-23-1003
  
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Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division

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Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance

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Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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  DOI: 10.4103/1673-5374.392889
  
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Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy

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  DOI: 10.4103/NRR.NRR-D-23-01592
  
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Sep 2024
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Brown adipose tissue-derived exosomes improve polycystic ovary syndrome in mice via STAT3/GPX4 signaling pathway

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  DOI: 10.1096/fj.202401346R
  
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HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma

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An adenosinergic positive feedback loop extends pharmacological cardioprotection duration

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  DOI: 10.1111/bph.17331
  
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A TBK1-independent primordial function of STING in lysosomal biogenesis

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The role of mitochondrial autophagy in osteoarthritis

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Engineering exosomes derived from TNF-α preconditioned IPFP-MSCs enhance both yield and therapeutic efficacy for osteoarthritis

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  DOI: 10.1186/s12951-024-02795-9
  
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Downregulation of Chloride voltage-gated channel 7 contributes to hyperalgesia following spared nerve injury

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  DOI: 10.1016/j.jbc.2024.107779
  
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Silencing of TXNIP attenuates oxidative stress injury in HEI-OC1 by inhibiting the activation of NLRP3 and NF-κB

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  DOI: 10.1016/j.heliyon.2024.e37753
  
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Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance

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TMEM252 inhibits epithelial–mesenchymal transition and progression in papillary thyroid carcinoma by regulating Notch1 expression

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  DOI: 10.1002/hed.27922
  
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LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration

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  DOI: 10.1038/s42255-024-01110-y
  
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Structural basis for the transport and substrate selection of human urate transporter 1

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The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network

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Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation

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  DOI: 10.1016/j.scr.2024.103531
  
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Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma

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Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6

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CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A

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  DOI: 10.1007/s00018-024-05285-1
  
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VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway

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Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage

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  DOI: 10.1016/j.isci.2024.110507
  
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52.53.155.43 52.53.155.43

Cancer-associated endocrine cells participate in pancreatic carcinogenesis

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  DOI: 10.1053/j.gastro.2024.07.016
  
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A hominoid-specific signaling axis regulating the tempo of synaptic maturation

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Ginsenoside Rb1 regulates CPT1A deacetylation to inhibit intramuscular fat infiltration after rotator cuff tear

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  DOI: 10.1016/j.isci.2024.110331
  
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The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells

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  DOI: 10.1016/j.devcel.2024.06.001
  
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The impact of quercetin and paclitaxel combination on ovarian cancer cells

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NAcM-OPT protects keratinocytes from H2O2-induced cell damage by promoting autophagy

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  DOI: 10.1111/nyas.15173
  
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Type III adenylyl cyclase is essential for follicular development in female mice and their reproductive lifespan

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  DOI: 10.1016/j.isci.2024.110293
  
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