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  1. Last 7 days
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    Opposing roles for AMPK in regulating distinct mitophagy pathways
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  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
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    SIRT3 differentially regulates lysine benzoylation from SIRT2 in mammalian cells
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  5. Nov 2024
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    Genome-wide mapping of native co-localized G4s and R-loops in living cells
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    Reduced mesencephalic astrocyte-derived neurotrophic factor ... : Neural Regeneration Research
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    Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation
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    Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms
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  10. Oct 2024
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    P16INK4A drives RB1 degradation by UTP14A-catalyzed K810 ubiquitination
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    NAPRT silencing in FH-deficient renal cell carcinoma confers therapeutic vulnerabilities via NAD+ depletion
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    Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
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    sciencedirect.com/science/article/pii/S2211124724011458
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    Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance
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    Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke
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    Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy
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  17. Sep 2024
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    Brown adipose tissue-derived exosomes improve polycystic ovary syndrome in mice via STAT3/GPX4 signaling pathway
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    HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma
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    An adenosinergic positive feedback loop extends pharmacological cardioprotection duration
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    A TBK1-independent primordial function of STING in lysosomal biogenesis
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    The role of mitochondrial autophagy in osteoarthritis
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    Engineering exosomes derived from TNF-α preconditioned IPFP-MSCs enhance both yield and therapeutic efficacy for osteoarthritis
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    Downregulation of Chloride voltage-gated channel 7 contributes to hyperalgesia following spared nerve injury
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    Silencing of TXNIP attenuates oxidative stress injury in HEI-OC1 by inhibiting the activation of NLRP3 and NF-κB
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  26. Aug 2024
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    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
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    TMEM252 inhibits epithelial–mesenchymal transition and progression in papillary thyroid carcinoma by regulating Notch1 expression
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    LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration
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    Structural basis for the transport and substrate selection of human urate transporter 1
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    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
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    Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation
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    Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma
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    Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6
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  35. Jul 2024
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    CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A
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    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
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    Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage
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    Cancer-associated endocrine cells participate in pancreatic carcinogenesis
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    A hominoid-specific signaling axis regulating the tempo of synaptic maturation
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    Ginsenoside Rb1 regulates CPT1A deacetylation to inhibit intramuscular fat infiltration after rotator cuff tear
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    The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells
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    The impact of quercetin and paclitaxel combination on ovarian cancer cells
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    NAcM-OPT protects keratinocytes from H2O2-induced cell damage by promoting autophagy
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    Type III adenylyl cyclase is essential for follicular development in female mice and their reproductive lifespan
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    PIK3CA mutations enhance the adipogenesis of ADSCs in facial infiltrating lipomatosis through TRPV1
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    MBNL2 promotes aging-related cardiac fibrosis via inhibited SUMOylation of Krüppel-like factor4
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    Lyssavirus matrix protein inhibits NLRP3 inflammasome assembly by binding to NLRP3
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    Macrophage migration inhibitory factor (MIF) suppresses mitophagy through disturbing the protein interaction of PINK1-Parkin in sepsis-associated acute kidney injury
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    Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity
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    PD-1 blockade plus COX inhibitors in dMMR metastatic colorectal cancer: Clinical, genomic, and immunologic analyses from the PCOX trial
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    Mycobacterial CpsA activates type I IFN signaling in macrophages via cGAS-mediated pathway
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    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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    Alpha-tocopherol inhibits ferroptosis and promotes neural function recovery in rats with spinal cord injury via downregulating Alox15
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    A novel Senescence-Based prognostic model unveils tumor interactions and drug resistance in colorectal cancer
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    Recombinant fibroblast growth factor 4 ameliorates axonal regeneration and functional recovery in acute spinal cord injury through altering microglia/macrophage phenotype
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    An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins
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    PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR
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    Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma
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    The Mediator Med23 controls a transcriptional switch for muscle stem cell proliferation and differentiation in muscle regeneration
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    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
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    Hypomethylation-associated LINC00987 downregulation induced lung adenocarcinoma progression by inhibiting the phosphorylation-mediated degradation of SND1
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    The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia
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    Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity
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  90. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin
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    AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis
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    The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD
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    Single-cell transcriptomics reveals the heterogeneity of the immune landscape of IDH-wildtype high-grade gliomas
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    hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility
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    SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury
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    BHLHE41 Suppresses Osteoclastogenesis and Abnormal Bone Resorption Disease via NFATc1
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    C/EBPα aggravates renal fibrosis in CKD through the NOX4-ROS-apoptosis pathway in tubular epithelial cells
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    Cardiac injury activates STING signaling via upregulating SIRT6 in macrophages after myocardial infarction
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    PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans
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    YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis
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    Comparative analyses of the Smith−Magenis syndrome protein RAI1 in mice and common marmoset monkeys
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    Construction of shared gene signature between rheumatoid arthritis and lung adenocarcinoma helps to predict the prognosis and tumor microenvironment of the LUAD patients
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    Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB
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    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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    The Role of DNMT1 and C/EBPα in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts
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    Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration
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    Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node
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    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
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  137. www.sciencedirect.com www.sciencedirect.com
    Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis
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    Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival
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    ITGB2-ICAM1 axis promotes liver metastasis in BAP1-mutated uveal melanoma with retained hypoxia and ECM signatures
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  140. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity
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  141. Dec 2023
  142. www.sciencedirect.com www.sciencedirect.com
    Generation of CRISPR-Cas9 edited human induced pluripotent stem cell line carrying BAG3 V468M mutation in its BAG domain
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis
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  144. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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    IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects
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    Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation
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    GDF15 is a major determinant of ketogenic diet-induced weight loss
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    NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance
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    Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair
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    APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread
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    ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation
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    Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma
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    Multi-omics analyses reveal bacteria and catalase associated with keloid disease
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    The hypothalamic steroidogenic pathway mediates susceptibility to inflammation-evoked depression in female mice
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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression
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    VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
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    Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity
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    Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma
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    m6A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
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  163. Nov 2023
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    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase
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    Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    Downregulation of ALKBH5 rejuvenates aged human mesenchymal stem cells and enhances their therapeutic efficacy in myocardial infarction
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    Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP
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    Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation
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    Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization
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    JUN mediates Glucocorticoid Resistance by stabilizing HIF1a in T-Cell Acute Lymphoblastic Leukemia
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    FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons
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    Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
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    Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia
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    The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy
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  178. Oct 2023
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    Methotrexate-based PROTACs as DHFR-specific chemical probes
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    MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis
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    Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
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    BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice
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    SIRT1 is an actionable target to restore p53 function in HPV-associated cancer therapy
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    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
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    Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
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    Increased NMDARs in neurons and glutamine synthetase in astrocytes underlying autistic-like behaviors of Gabrb1-/- mice
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    1. scibot 26 Aug 2023
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2023.107476

      Resource: (Proteintech Cat# 60004-1-Ig, RRID:AB_2107436)

      Curator: @scibot

      SciCrunch record: RRID:AB_2107436

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      RRID:AB_2107436
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    ncbi.nlm.nih.gov/pmc/articles/PMC10433130/