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Table 2 Validated primary antibodies for identifying various major nephron segments

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An inducible model of human post-implantation development derived from primed and naive stem cells

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SMAD4 Deficiency Promotes Pancreatic Cancer Progression and Confers Susceptibility to TGFβ Inhibition

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Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations

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Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases

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FBXW5 Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Through the KLF13/TROAP Signaling Pathway

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Targeting FGFR4 abrogates HNF1A-driven metastasis in pancreatic ductal adenocarcinoma

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Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer

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Matrix Stiffness Regulates TGFβ1‐Induced αSMA Expression via a G9a‐LATS‐YAP Signaling Cascade

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EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration

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TFE3-splicing factor fusions represent functional drivers and druggable targets in translocation renal cell carcinoma

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1-s2.0-S2589004225013215-main-html.html

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Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids

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Jun 2025
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Cingulin is an RNA-binding protein promoting pancreatic cancer through enhancing importin 7-mediated phospho-ERK nuclear translocation

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52.53.155.43/40d57cf5e469615dd789036d1af2f800d0eb4416/PDF-html.html
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Breaking Barriers: A Protocol to Investigate Intestinal Pathogen Adhesion, Invasion, and Translocation Through In Vitro, In Vivo, and Imaging Technologies

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1. scibot 14 Jun 2025
  
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CRISPR/Cas9 Screening Highlights PFKFB3 Gene as a Major Contributor to 5-Fluorouracil Resistance in Esophageal Cancer

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P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids

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An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer

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Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity

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Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model

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Chromosomal Instability Is Associated with cGAS–STING Activation in EGFR-TKI Refractory Non-Small-Cell Lung Cancer

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ARHGAP12 and ARHGAP29 exert distinct regulatory effects on switching between two cell morphological states through GSK-3 activity

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Adhesion strength of tumor cells predicts metastatic disease in vivo

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Feb 2025
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Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis

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Single-cell and spatial transcriptomics reveal a potential role of ATF3 in brain metastasis of lung adenocarcinoma

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  DOI: 10.21037/tlcr-24-784
  
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Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer

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  DOI: 10.1158/0008-5472.CAN-23-3987
  
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aacrjournals.org/cancerres/article/84/20/3371/749080/Cancer-Associated-Fibroblasts-Expressing-Sulfatase
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TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma

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  DOI: 10.1158/0008-5472.CAN-22-3009
  
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aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
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Differentiation of lung tissue-resident c-Kit+ cells into microvascular endothelial cells alleviates pulmonary vascular remodeling

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P-cadherin-dependent adhesions are required for single lumen formation and HGF-mediated cell protrusions during epithelial morphogenesis

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Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells

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Targeting ROR2 homooligomerization disrupts ROR2-dependent signaling and suppresses stem-like cell properties of human breast adenocarcinoma

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Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer

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Light-dark shift promotes colon carcinogenesis through accelerated colon aging

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P-cadherin mechanoactivates tumor-mesothelium metabolic coupling to promote ovarian cancer metastasis

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Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer

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Microbiota-derived short-chain fatty acids determine stem cell characteristics of gastric chief cells

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Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s disease

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Mapping and tracing Grem1+ stromal cells in an ApcMin/+ mouse utilizing cryopreserved intestinal sections prepared via modified Swiss-roll technique

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Reprogramming of fibroblasts into cancer-associated fibroblasts via IGF2-mediated autophagy promotes metastasis of lung cancer cells

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can-24-1703-html.html

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A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells

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CircZNF609/miR-324-5p/VDAC1 axis promotes malignant progression of ovarian cancer cells

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Global isonicotinylome analysis identified SMAD3 isonicotinylation promotes liver cancer cell epithelial–mesenchymal transition and invasion

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Cancer cell – fibroblast crosstalk via HB-EGF/EGFR/MEK signaling promotes expression of macrophage chemo-attractants in squamous cell carcinoma

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Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis

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TGF-β and RAS jointly unmask primed enhancers to drive metastasis

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Beyond mitochondrial transfer, cell fusion rescues metabolic dysfunction and boosts malignancy in adenoid cystic carcinoma

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Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation

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Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6

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Generation and characterization of a human iPSC line expressing EGFP-tagged CDH1, KSCBi002-A-3

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Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells

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The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization

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Substrate Stiffness Alters Layer Architecture and Biophysics of Human Induced Pluripotent Stem Cells to Modulate their Differentiation Potential

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Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response

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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

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Patterning in stratified epithelia depends on cell–cell adhesion

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Regulation of the DLC3 tumor suppressor by a novel phosphoswitch

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Bioengineered human colon organoids with in vivo-like cellular complexity and function

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Coexisting mechanisms of luminogenesis in pancreatic cancer-derived organoids

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Myosin II mediates Shh signals to shape dental epithelia via control of cell adhesion and movement

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Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus.

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DDX56 promotes EMT and cancer stemness via MELK-FOXM1 axis in hepatocellular carcinoma

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Secretion of WNT7A by UC-MSCs assist in promoting the endometrial epithelial regeneration

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The Exocyst Complex is Required for the Trafficking and Delivery of KCa3.1 to the Basolateral Membrane of Polarized Epithelia

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  C. Other antibodies used in the study.
  
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Transcription factor activating enhancer-binding protein 2ε (AP2ε) modulates phenotypic plasticity and progression of malignant melanoma

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Patterning and folding of intestinal villi by active mesenchymal dewetting

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Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition

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FGF signaling regulates salivary gland branching morphogenesis by modulating cell adhesion

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The Janus kinase 1 is critical for pancreatic cancer initiation and progression

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Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis

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Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease

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Intraepithelial mast cells drive gasdermin C-mediated type 2 immunity

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Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection

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Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer

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Mechanical strengthening of cell-cell adhesion during mouse embryo compaction

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Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer

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Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation

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Telomere dysfunction alters intestinal stem cell dynamics to promote cancer

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Defining the contribution of Troy-positive progenitor cells to the mouse esophageal epithelium

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Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance

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Depletion of PHLDB2 Suppresses Epithelial–Mesenchymal Transition and Enhances Anti-Tumor Immunity in Head and Neck Squamous Cell Carcinoma

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Hypoxia at 3D organoid establishment selects essential subclones within heterogenous pancreatic cancer

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Single-cell assessment of primary and stem cell-derived human trophoblast organoids as placenta-modeling platforms

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The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

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OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma

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Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis

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Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis

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RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling

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ERK-mediated curvature feedback regulates branching morphogenesis in lung epithelial tissue

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Gasdermin-D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway

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A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling

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Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin

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A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas

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Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion

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Heterogeneity and transcriptional drivers of triple-negative breast cancer

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Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma

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Hypoxia induces hepatocellular carcinoma metastasis via the HIF-1α/METTL16/lnc-CSMD1-7/RBFOX2 axis

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Cell–cell adhesion drives patterning in stratified epithelia

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CLMP is a tumor suppressor that determines all-trans retinoic acid response in colorectal cancer

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Protocol for isolation of signet ring cells from human gastric mucosa

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Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism

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Highly-parallel production of designer organoids by mosaic patterning of progenitors

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Impact of CRISPR/Cas9-Mediated CD73 Knockout in Pancreatic Cancer

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In vitro vascularized immunocompetent patient-derived model to test cancer therapies

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Molecular anatomy of adult mouse leptomeninges

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In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy

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Chemoproteomic strategy identified p120-catenin glutathionylation regulates E-cadherin degradation and cell migration

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Fusobacterium nucleatum promotes colorectal cancer metastasis by excretion of miR-122-5p from cells via exosomes

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CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis

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Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer

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Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

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Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells

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HOXA11 promotes lymphatic metastasis of gastric cancer via transcriptional activation of TGFβ1

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Label-free imaging of 3D pluripotent stem cell differentiation dynamics on chip

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Interactions between host and intestinal crypt-resided biofilms are controlled by epithelial fucosylation

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TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2

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SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma

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Breast cancer cell mesenchymal transition and metastasis directed by DAP5/eIF3d-mediated selective mRNA translation

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USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis

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Investigating the effects of 7-ketocholesterol on retinal pigment epithelium bioenergetics

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Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion

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Cancer cell-autonomous cGAS-STING response confers drug resistance

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KDM4B down-regulation facilitated breast cancer cell stemness via PHGDH upregulation in H3K36me3-dependent manner

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Lacking ARHGAP25 mitigates the symptoms of autoantibody-induced arthritis in mice

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Amino acid solution mitigates hypothermia response and intestinal damage following exertional heat stroke in male mice

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Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma

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Exercise improves homeostasis of the intestinal epithelium by activation of APJ-AMPK signaling

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Generation of endogenously tagged E-cadherin cells using gene editing via non-homologous end joining

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Ex utero monkey embryogenesis from blastocyst to early organogenesis

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The Journal of Physiology - 2023 - Chae - Exercise improves homeostasis of the intestinal epithelium by activation of-html.html

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Independent control over cell patterning and adhesion on hydrogel substrates for tissue interface mechanobiology

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Immune mechanisms shape the clonal landscape during early progression of prostate cancer

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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

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Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells

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A junction-dependent mechanism drives murine mammary cell intercalation for ductal elongation

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Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

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TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state

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IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells

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Generating human blastoids modeling blastocyst-stage embryos and implantation

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CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance

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Goji berry (Lycium barbarum) inhibits the proliferation, adhesion, and migration of oral cancer cells by inhibiting the ERK, AKT, and CyclinD cell signaling pathways: an in-vitro study

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Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

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RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation

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A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling

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Identification of Genes Associated with Liver Metastasis in Pancreatic Cancer Reveals PCSK6 as a Crucial Mediator

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ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells

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The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response

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Negative E-cadherin expression on bone marrow myeloma cell membranes is associated with extramedullary disease

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Hedgehog regulation of epithelial cell state and morphogenesis in the larynx

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CRABP2 is associated with thyroid cancer recurrence and promotes invasion via the integrin/FAK/AKT pathway

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Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis

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The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma

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The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells

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Pulmonary neuroendocrine cells sense succinate to stimulate myoepithelial cell contraction

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Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells

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A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway

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A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis

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Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways

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Decoding the activated stem cell phenotype of the neonatally maturing pituitary

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Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines

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Tumorigenic cell selection and substrate rigidity manipulation using 2D and 3D extracellular matrices

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Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis

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Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity

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Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway

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Organoid-derived intestinal epithelial cells are a suitable model for preclinical toxicology and pharmacokinetic studies

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Lymphatics act as a signaling hub to regulate intestinal stem cell activity

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Protocols for SARS-CoV-2 infection in primary ocular cells and eye organoids

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The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys

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Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens

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TNFɑ Antagonist in Combination with PD-1 Blocker to Prevent or Retard Malignant Transformation of B[a]P-induced Chronic Lung Inflammation

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Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation

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Single-cell proteomics defines the cellular heterogeneity of localized prostate cancer

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  DOI: 10.1016/j.xcrm.2022.100604
  
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Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche

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Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer

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Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer

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Peritoneal Restoration by Repurposing Vitamin D Inhibits Ovarian Cancer Dissemination via Blockade of the TGF-β1/Thrombospondin-1 Axis

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Delicate regulation of IL-1β-mediated inflammation by cyclophilin A

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A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

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Protocol for serial organoid formation assay using primary colorectal cancer tissues to evaluate cancer stem cell activity

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Crosstalk between ERK and MRTF-A signaling regulates TGFβ1-induced epithelial-mesenchymal transition

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F1000Research Article: Negative E-cadherin expression on bone marrow myeloma cell membranes is associated with extramedullary disease.

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  DOI: 10.12688/f1000research.109551.1
  
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Patterning the embryonic pulmonary mesenchyme

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DRAM-4 and DRAM-5 are compensatory regulators of autophagy and cell survival in nutrient-deprived conditions

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  DOI: 10.1111/febs.16365
  
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Interferon-γ promotes monocyte-mediated lung injury during influenza infection

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Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin

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