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    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
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    Intraepithelial mast cells drive gasdermin C-mediated type 2 immunity
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    Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
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    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
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    Mechanical strengthening of cell-cell adhesion during mouse embryo compaction
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    Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer
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    Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation
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    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
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    Defining the contribution of Troy-positive progenitor cells to the mouse esophageal epithelium
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  12. Mar 2024
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    Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance
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  14. Feb 2024
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    Depletion of PHLDB2 Suppresses Epithelial–Mesenchymal Transition and Enhances Anti-Tumor Immunity in Head and Neck Squamous Cell Carcinoma
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    Hypoxia at 3D organoid establishment selects essential subclones within heterogenous pancreatic cancer
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    Single-cell assessment of primary and stem cell-derived human trophoblast organoids as placenta-modeling platforms
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    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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    OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma
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    Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis
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    Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis
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    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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    ERK-mediated curvature feedback regulates branching morphogenesis in lung epithelial tissue
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    Gasdermin-D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway
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    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
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    Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin
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    A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
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    Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion
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    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    Hypoxia induces hepatocellular carcinoma metastasis via the HIF-1α/METTL16/lnc-CSMD1-7/RBFOX2 axis
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    Cell–cell adhesion drives patterning in stratified epithelia
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  35. Nov 2023
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    CLMP is a tumor suppressor that determines all-trans retinoic acid response in colorectal cancer
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    Protocol for isolation of signet ring cells from human gastric mucosa
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    Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism
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    Highly-parallel production of designer organoids by mosaic patterning of progenitors
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  40. Oct 2023
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    Impact of CRISPR/Cas9-Mediated CD73 Knockout in Pancreatic Cancer
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    In vitro vascularized immunocompetent patient-derived model to test cancer therapies
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  43. Sep 2023
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    Molecular anatomy of adult mouse leptomeninges
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    In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy
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    Chemoproteomic strategy identified p120-catenin glutathionylation regulates E-cadherin degradation and cell migration
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    Fusobacterium nucleatum promotes colorectal cancer metastasis by excretion of miR-122-5p from cells via exosomes
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    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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    SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
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    Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma
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    Independent control over cell patterning and adhesion on hydrogel substrates for tissue interface mechanobiology
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    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
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    Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
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    A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling
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    Identification of Genes Associated with Liver Metastasis in Pancreatic Cancer Reveals PCSK6 as a Crucial Mediator
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  92. Dec 2022
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    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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    The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response
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    Negative E-cadherin expression on bone marrow myeloma cell membranes is associated with extramedullary disease
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  97. Nov 2022
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    CRABP2 is associated with thyroid cancer recurrence and promotes invasion via the integrin/FAK/AKT pathway
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    Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
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  100. Oct 2022
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    The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma
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  102. Sep 2022
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    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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  106. Aug 2022
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    A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway
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    A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
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    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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  110. Jul 2022
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    Decoding the activated stem cell phenotype of the neonatally maturing pituitary
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    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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    Tumorigenic cell selection and substrate rigidity manipulation using 2D and 3D extracellular matrices
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    Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis
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    Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity
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    Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway
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  117. Jun 2022
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    Organoid-derived intestinal epithelial cells are a suitable model for preclinical toxicology and pharmacokinetic studies
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    Lymphatics act as a signaling hub to regulate intestinal stem cell activity
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    Protocols for SARS-CoV-2 infection in primary ocular cells and eye organoids
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  121. May 2022
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    The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys
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    Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens
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    TNFɑ Antagonist in Combination with PD-1 Blocker to Prevent or Retard Malignant Transformation of B[a]P-induced Chronic Lung Inflammation
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    Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation
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    Single-cell proteomics defines the cellular heterogeneity of localized prostate cancer
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    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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  130. Mar 2022
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    Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer
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    Peritoneal Restoration by Repurposing Vitamin D Inhibits Ovarian Cancer Dissemination via Blockade of the TGF-β1/Thrombospondin-1 Axis
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    Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
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    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
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    Protocol for serial organoid formation assay using primary colorectal cancer tissues to evaluate cancer stem cell activity
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    Crosstalk between ERK and MRTF-A signaling regulates TGFβ1-induced epithelial-mesenchymal transition
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    Interferon-γ promotes monocyte-mediated lung injury during influenza infection
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    Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
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  142. Feb 2022
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    Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
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    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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    A positive feed-forward loop between Fusobacterium nucleatum and ethanol metabolism reprogramming drives laryngeal cancer progression and metastasis
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    Identification of treatment-induced vulnerabilities in pancreatic cancer patients using functional model systems
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    Radiation induces epithelial to mesenchymal transition via upregulation of PD-L1 in nasopharyngeal carcinoma cell
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    In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration
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  149. Jan 2022
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    Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity
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  151. Dec 2021
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    Substratum stiffness regulates Erk signaling dynamics through receptor-level control
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    MATISSE: An analysis protocol for combining imaging mass cytometry with fluorescence microscopy to generate single-cell data
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    Pharmacological targeting of Sam68 functions in colorectal cancer stem cells
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    Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1
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  158. Nov 2021
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    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
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    A novel jamming phase diagram links tumor invasion to non-equilibrium phase separation
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  162. Oct 2021
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    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
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    Kinase DYRK2 acts as a regulator of autophagy and an indicator of favorable prognosis in gastric carcinoma
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    Proteomic and phosphoproteomic analyses identify liver-related signaling in retinal pigment epithelial cells during EMT
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    Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival
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    The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment
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    Uterine epithelial LIF receptors contribute to implantation chamber formation in blastocyst attachment
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  169. Sep 2021
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    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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    Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche
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  172. Aug 2021
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    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
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    Entosis is induced by UV radiation.
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    Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium
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    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
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    Genomic Function of Estrogen Receptor Beta In Endometriosis
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    Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium
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    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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  188. Jun 2021
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    Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction
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    Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling
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  193. May 2021
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    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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    SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium
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    Chronic restraint stress promotes the mobilization and recruitment of myeloid-derived suppressor cells through β-adrenergic-activated CXCL5-CXCR2-Erk signaling cascades
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  197. www.sciencedirect.com www.sciencedirect.com
    Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua
    1
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  198. www.sciencedirect.com www.sciencedirect.com
    Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury
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  199. www.sciencedirect.com www.sciencedirect.com
    Capturing Cardiogenesis in Gastruloids
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  200. www.sciencedirect.com www.sciencedirect.com
    SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt
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  201. www.sciencedirect.com www.sciencedirect.com
    Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells
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    Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells
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    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
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    ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization
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  205. www.sciencedirect.com www.sciencedirect.com
    The embryonic ontogeny of the gonadal somatic cells in mice and monkeys
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  206. Apr 2021
  207. www.sciencedirect.com www.sciencedirect.com
    Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation
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    Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells
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    Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma
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    A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelialization
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    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
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    Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer
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    Quantitative chemoproteomics reveals O-GlcNAcylation of cystathionine γ-lyase (CSE) represses trophoblast syncytialization
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  215. europepmc.org europepmc.org
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  216. www.cell.com www.cell.com
    Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
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      DOI: 10.1016/j.ccell.2020.12.014

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    cell.com/cancer-cell/abstract/S1535-6108(20)30662-0
  217. www.sciencedirect.com www.sciencedirect.com
    RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis
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    sciencedirect.com/science/article/pii/S1534580721002033
  218. Mar 2021
  219. www.sciencedirect.com www.sciencedirect.com
    Alisertib inhibits migration and invasion of EGFR-TKI resistant cells by partially reversing the epithelial-mesenchymal transition
    1
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      E-cadherin

      DOI: 10.1016/j.bbamcr.2021.119016

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    Isorhamnetin Inhibits Human Gallbladder Cancer Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway Inactivation
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      DOI: 10.3389/fphar.2021.628621

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    ncbi.nlm.nih.gov/pmc/articles/PMC7927673/
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    Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
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  222. Feb 2021
  223. academic.oup.com academic.oup.com
    MiR-221/222 inhibit insulin production of pancreatic β-cells in mice
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      DOI: 10.1210/endocr/bqz027

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    academic.oup.com/endo/article/161/1/bqz027/5639771
  224. Jan 2021
  225. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
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      DOI: 10.7554/eLife.59142

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    ncbi.nlm.nih.gov/pmc/articles/PMC7803373/
  226. Dec 2020
  227. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures
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    Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids
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  229. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MASTL promotes cell contractility and motility through kinase-independent signaling
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  230. Nov 2020
  231. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells
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  232. Oct 2020
  233. academic.oup.com academic.oup.com
    Uterine scar leads to adverse pregnant consequence through impairing the response of endometrium to steroids
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      DOI: 10.1210/endocr/bqaa174

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  234. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pregnancy success in mice requires appropriate cannabinoid receptor signaling for primary decidua formation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7550189/
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    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
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  236. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    m6A RNA methylation impacts fate choices during skin morphogenesis
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