222 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Multi-omics analyses of cancer-linked clinical salmonellae reveal bacterial-induced host metabolic shift and mTOR-dependent cell transformation
    8
    1. scibot 22 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    2. scibot 21 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    3. scibot 21 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    4. scibot 20 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    5. scibot 19 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    6. scibot 18 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    7. scibot 17 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    8. scibot 16 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    sciencedirect.com/science/article/pii/S2211124724012828
  3. Nov 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Multi-omics analyses of cancer-linked clinical salmonellae reveal bacterial-induced host metabolic shift and mTOR-dependent cell transformation
    9
    1. scibot 15 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    2. scibot 14 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    3. scibot 13 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    4. scibot 12 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    5. scibot 11 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    6. scibot 10 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    7. scibot 09 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    8. scibot 08 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_330944
    9. scibot 07 Nov 2024
      RRID:AB_330944

      Traceback (most recent call last): File "create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    sciencedirect.com/science/article/pii/S2211124724012828
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    Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27
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    1. scibot 14 Nov 2024
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      DOI: 10.1016/j.cub.2024.10.061

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    sciencedirect.com/science/article/pii/S096098222401457X
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    Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development
    1
    1. scibot 07 Nov 2024
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      DOI: 10.1523/JNEUROSCI.0072-24.2024

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    jneurosci.org/content/44/42/e0072242024
  7. Aug 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
    1
    1. scibot 23 Aug 2024
      AB_330944

      DOI: 10.1016/j.molcel.2024.08.006

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    sciencedirect.com/science/article/pii/S1097276524006609
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    RIPK1 Promotes Energy Sensing by the mTORC1 Pathway
    1
    1. scibot 02 Aug 2024
      S6K phospho-Thr389

      DOI: 10.1016/j.molcel.2020.11.008

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30786-3
  10. Jul 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial perturbations in low-protein-diet-fed mice are associated with altered neutrophil development and effector functions
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      DOI: 10.1016/j.celrep.2024.114493

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    sciencedirect.com/science/article/pii/S2211124724008222
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dystrophin S3059 phosphorylation partially attenuates denervation atrophy in mouse tibialis anterior muscles
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    1. scibot 17 Jul 2024
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      DOI: 10.14814/phy2.16145

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    ncbi.nlm.nih.gov/pmc/articles/PMC11245571/
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    A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
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    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.devcel.2020.07.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC7606764/
  14. Jun 2024
  15. 52.53.155.43 52.53.155.43
    Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency
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    1. scibot 06 Jun 2024
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      DOI: 10.1101/2024.02.09.579580

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      DOI: 10.1101/2024.02.09.579580

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    52.53.155.43/be49547c4f9e1293474726024249294abe2db848/2024.02.09.579580v1.full-html.html
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
    1
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      DOI: 10.1016/j.isci.2024.109983

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  17. May 2024
  18. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia
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      DOI: 10.1113/JP285339

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285339
  19. 52.53.155.43 52.53.155.43
    Everolimus exerts anticancer effects through inhibiting the interaction of matrix metalloproteinase-7 with syndecan-2 in colon cancer cells
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    1. scibot 24 May 2024
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      DOI: 10.1152/ajpcell.00669.2023

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      DOI: 10.1152/ajpcell.00669.2023

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    52.53.155.43/76598b44d554c4165a9f84a25bc34c671709ff41/lee-et-al-2024-everolimus-exerts-anticancer-effects-through-inhibiting-the-interaction-of-matrix-metalloproteinase-7-html.html
  20. 52.53.155.43 52.53.155.43
    2024.02.09.579580v1.full-html.html
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      DOI: 10.1038/nature05972

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  21. 52.53.155.43 52.53.155.43
    Beyond Glycolysis: Aldolase A is a Novel Effector in Reelin Mediated Dendritic Development
    1
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      DOI: 10.1101/2024.01.12.575269

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  22. Apr 2024
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    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
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      DOI: 10.1016/j.celrep.2024.114149

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    sciencedirect.com/science/article/pii/S2211124724004777
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    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
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      DOI: 10.1016/j.celrep.2024.114094

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      DOI: 10.1016/j.celrep.2024.114094

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    sciencedirect.com/science/article/pii/S2211124724004224
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    A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism
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      DOI: 10.1016/j.celrep.2024.114119

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    sciencedirect.com/science/article/pii/S2211124724004479
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle
    1
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      DOI: 10.1038/s41598-024-58716-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10998866/
  27. Feb 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytotoxin-mediated silk gland organ dysfunction diverts resources to enhance silkworm fecundity by potentiating nutrient-sensing IIS/TOR pathways
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      DOI: 10.1016/j.isci.2024.108853

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    ncbi.nlm.nih.gov/pmc/articles/PMC10830876/
  29. Jan 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  31. Dec 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling
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      DOI: 10.1016/j.devcel.2023.11.023

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    sciencedirect.com/science/article/pii/S1534580723006214
  33. www.sciencedirect.com www.sciencedirect.com
    Sequestration of translation initiation factors in p62 condensates
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      DOI: 10.1016/j.celrep.2023.113583

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    sciencedirect.com/science/article/pii/S2211124723015954
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    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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      DOI: 10.1016/j.molcel.2023.11.023

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    sciencedirect.com/science/article/pii/S1097276523009681
  35. Nov 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Short salsalate administration affects cell proliferation, metabolism, and inflammation in polycystic kidney disease
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      DOI: 10.1016/j.isci.2023.108278

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    sciencedirect.com/science/article/pii/S2589004223023556
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    HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B
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      DOI: 10.1016/j.xcrm.2023.101285

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    sciencedirect.com/science/article/pii/S2666379123004792
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRL2 inhibition elevates PTEN protein and ameliorates progression of acute myeloid leukemia
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      DOI: 10.1172/jci.insight.170065

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    ncbi.nlm.nih.gov/pmc/articles/PMC10619439/
  39. 52.53.155.43 52.53.155.43
    s11684-022-0959-5 (1)-html.html
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  40. Oct 2023
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    The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes
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    Underpinning the food matrix regulation of post-exercise myofibrillar protein synthesis by comparing salmon ingestion versus the sum of its isolated nutrients in healthy young adults
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    Resistance wheel running improves contractile strength, but not metabolic capacity, in a murine model of volumetric muscle loss injury
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    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
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    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
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    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
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    Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
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  50. Jul 2023
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    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
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    Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model via induction of Apoptosis
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  54. Jun 2023
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    Chronic neuronal inactivity utilizes the mTOR-TFEB pathway to drive transcription-dependent autophagy for homeostatic up-scaling
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  56. May 2023
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    Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
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    Rapamycin treatment unmasks a sex-specific pattern of scar expansion of the infarcted rat heart: The relationship between mTOR and KATP channel
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    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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    Concomitant inhibition of PPARγ and mTORC1 induces the differentiation of human monocytes into highly immunogenic dendritic cells
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  66. Feb 2023
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  71. Jan 2023
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    Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin
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    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
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    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
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    Identification of serum and glucocorticoid-regulated kinase 1 as a regulator of signal transducer and activator of transcription 3 signaling
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    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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    TORC1 inactivation promotes APC/C-dependent mitotic slippage in yeast and human cells
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  106. Jan 2022
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    Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4
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  109. Nov 2021
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    Electroconvulsive seizure inhibits the mTOR signaling pathway via AMPK in the rat frontal cortex
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    ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy
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  117. Sep 2021
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    Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
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  130. Jul 2021
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    Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
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    An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
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      phospho‐p70S6 kinase (Thr389) rabbit mAb

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    Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time
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  135. Jun 2021
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    Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties
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  137. May 2021
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    TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
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    AMPK‐regulated miRNA‐210‐3p is activated during ischaemic neuronal injury and modulates PI3K‐p70S6K signalling
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    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
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    Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis
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    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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  145. Apr 2021
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    A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes
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    Very-low-protein diets lead to reduced food intake and weight loss, linked to inhibition of hypothalamic mTOR signaling, in mice
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    Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression
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  150. Mar 2021
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  152. Feb 2021
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    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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  155. Jan 2021
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    Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma
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    Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity
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  160. Dec 2020
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    Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth
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    Hetero-oligomerization of Rho and Ras GTPases Connects GPCR Activation to mTORC2-AKT Signaling
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  163. Nov 2020
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    Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
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  166. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TORC1 selectively regulates synaptic maturation and input convergence in the developing visual system
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  167. Oct 2020
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism
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    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
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    The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest
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  171. Sep 2020
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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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  173. elifesciences.org elifesciences.org
    UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity
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    Vessel-derived angiocrine IGF-1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis
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    Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations
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    Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice
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    Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1
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    The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis
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    mTORC1 Signaling Controls TLR2-Mediated T-Cell Activation by Inducing TIRAP Expression
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    The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance
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    mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis
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    Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
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    Hyperactivation of TORC1 Drives Resistance to the Pan-HER Tyrosine Kinase Inhibitor Neratinib in HER2-Mutant Cancers
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    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
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    Aster‐C coordinates with COP I vesicles to regulate lysosomal trafficking and activation of mTORC1
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      Anti‐phospho‐S6K

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  186. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    β2‐adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy
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  187. elifesciences.org elifesciences.org
    Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
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  188. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation
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  189. Jan 2020
  190. www.sciencedirect.com www.sciencedirect.com
    Mechanistic target of rapamycin (mTOR) implicated in plasticity of the reproductive axis during social status transitions
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    Adaptive Fibrogenic Reprogramming of Osteosarcoma Stem Cells Promotes Metastatic Growth
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