238 Matching Annotations
  1. Last 7 days
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    Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5
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  3. Sep 2024
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    TGF-β and RAS jointly unmask primed enhancers to drive metastasis
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  5. Aug 2024
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    Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans
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    sciencedirect.com/science/article/pii/S1550413124002912
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    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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    sciencedirect.com/science/article/pii/S109727652400618X
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    In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma
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    Loss of Fbxw7 in Sertoli cells impairs testis development and causes infertility in mice
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    academic.oup.com/biolreprod/biolreprod/advance-article-abstract/doi/10.1093/biolre/ioz230/5688712
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    Variants in CAPZA2, a member of a F-actin capping complex, cause intellectual disability and developmental delay
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      mouse anti-α-tubulin

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    Lithium improves cell viability in psychosine‐treated MO3.13 human oligodendrocyte cell line via autophagy activation
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  12. Jul 2024
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    Role of palmitoylation on the neuronal glycine transporter GlyT2
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      DOI: 10.1111/jnc.16181

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    Efficient, specific, and combinatorial control of endogenous exon splicing with dCasRx-RBM25
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    PPAR_Interaction_with_UBR5_ATMIN_Promot-html.html
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    Monitoring melanoma patients on treatment reveals a distinct macrophage population driving targeted therapy resistance
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  17. Jun 2024
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    Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation
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    sciencedirect.com/science/article/pii/S258900422401424X
  19. May 2024
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    Direct interrogation of context-dependent GPCR activity with a universal biosensor platform
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    Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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  23. Apr 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biochemical Fractionation of Human α-Synuclein in a Drosophila Model of Synucleinopathies
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      DOI: 10.3390/ijms25073643

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    Age-dependent regulation of axoglial interactions and behavior by oligodendrocyte AnkyrinG
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    sciencedirect.com/science/article/pii/S2211124724003723
  27. Mar 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
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  31. Feb 2024
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    Biochemical fractionation of human α-Synuclein in a Drosophila model of synucleinopathies
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  33. Jan 2024
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    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    Glioblastoma and its treatment are associated with extensive accelerated brain aging
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  36. Dec 2023
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    Age-dependent loss of cohesion protection in human oocytes
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    Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors
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    Mir324 knockout regulates the structure of dendritic spines and impairs hippocampal long-term potentiation
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    MiR-138-5p Upregulation during Neuronal Maturation Parallels with an Increase in Neuronal Survival
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      DOI: 10.3390/ijms242216509

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  41. Nov 2023
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    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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    Aryl Hydrocarbon Receptor is a Tumor Promoter in MYCN-Amplified Neuroblastoma Cells Through Suppression of Differentiation
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    sciencedirect.com/science/article/pii/S2589004223023805
  44. Oct 2023
  45. link.springer.com link.springer.com
    Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A2A receptors
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    link.springer.com/article/10.1007/s00018-023-04983-6
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    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
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    Regulation of STING activity in DNA sensing by ISG15 modification
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  48. www.tandfonline.com www.tandfonline.com
    Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders
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      DOI: 10.1080/21678421.2023.2261979

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    tandfonline.com/doi/abs/10.1080/21678421.2023.2261979
  49. Sep 2023
  50. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
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  51. Aug 2023
  52. www.science.org www.science.org
    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions
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  54. Jul 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage
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    Reduced histone gene copy number disrupts Drosophila Polycomb function
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  57. Jun 2023
  58. www.sciencedirect.com www.sciencedirect.com
    Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40
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    Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas
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  60. May 2023
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    Evaluation of Poly(N-Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells
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  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astrocytic A2A receptors silencing negatively impacts hippocampal synaptic plasticity and memory of adult mice
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    A ubiquitin fusion reporter to monitor muscle proteostasis in C. elegans
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    Miniaturized and multiplexed high-content screening of drug and immune sensitivity in a multichambered microwell chip
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  65. Apr 2023
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    Piezo1 induces endothelial responses to shear stress via soluble adenylyl Cyclase-IP3R2 circuit
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    Reduced histone gene copy number disrupts Drosophila Polycomb function
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    Lysine long-chain fatty acylation regulates the TEAD transcription factor
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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  71. Mar 2023
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    The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11
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  73. Jan 2023
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    Chemogenetic activation of astrocytes promotes remyelination and restores cognitive deficits in visceral hypersensitive rats
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  75. Dec 2022
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    Autocleavage of separase suppresses its premature activation by promoting binding to cyclin B1
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  77. Nov 2022
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis
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    Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication
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    Differentiation of crescent-forming kidney progenitor cells into podocytes attenuates severe glomerulonephritis in mice
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    Structural and functional basis of mammalian microRNA biogenesis by Dicer
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  82. Oct 2022
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolomic fingerprinting of renal disease progression in Bardet-Biedl syndrome reveals mitochondrial dysfunction in kidney tubular cells
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  84. Sep 2022
  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Aversive memory reactivation: A possible role for delta oscillations in the hippocampus–amygdala circuit
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    A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling
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  87. Aug 2022
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    A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing
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    Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis
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  90. Jun 2022
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    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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    Protein disulfide isomerase PDI-6 regulates Wnt secretion to coordinate inter-tissue UPRmt activation and lifespan extension in C. elegans
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    miR-182-5p Regulates Nogo-A Expression and Promotes Neurite Outgrowth of Hippocampal Neurons In Vitro
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  94. May 2022
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    The Taspase1/Myosin1f-axis regulates filopodia dynamics
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    Nde1 is required for heterochromatin compaction and stability in neocortical neurons
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  97. Mar 2022
  98. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sex hormones modulate pathogenic processes in experimental traumatic brain injury
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    SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones
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    BMI-1 regulates DNA end resection and homologous recombination repair
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    The ARM repeat domain of hemocyanin interacts with MKK4 to modulate antimicrobial peptides expression
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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  104. Feb 2022
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    Systematic mapping of nuclear domain-associated transcripts reveals speckles and lamina as hubs of functionally distinct retained introns
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    Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas
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    TORC1 inactivation promotes APC/C-dependent mitotic slippage in yeast and human cells
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    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo
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    Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls
    1
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      RRID:AB_477582

      DOI: 10.1016/j.scr.2021.102435

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  155. www.sciencedirect.com www.sciencedirect.com
    C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation
    1
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      DOI: 10.1016/j.neuron.2021.05.020

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  156. www.nature.com www.nature.com
    Reprogramming of microRNA expression via E2F1 downregulation promotes Salmonella infection both in infected and bystander cells
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      DOI: 10.1038/s41467-021-23593-z

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  157. www.sciencedirect.com www.sciencedirect.com
    XRCC1 prevents toxic PARP1 trapping during DNA base excision repair
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    PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome
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  159. May 2021
  160. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein
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      mouse monoclonal anti-tubulin

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  161. www.sciencedirect.com www.sciencedirect.com
    An activity-dependent determinant of synapse elimination in the mammalian brain
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program
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  163. www.sciencedirect.com www.sciencedirect.com
    O2-Dependent Protein Internalization Underlies Astrocytic Sensing of Acute Hypoxia by Restricting Multimodal TRPA1 Channel Responses
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      DOI: 10.1016/j.cub.2020.06.047

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    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
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  165. Apr 2021
  166. www.sciencedirect.com www.sciencedirect.com
    The chromatin-remodeling protein BAF60/SWP73A regulates the plant immune receptor NLRs
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    Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor Design
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    Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation
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  169. www.sciencedirect.com www.sciencedirect.com
    SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation
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      α-tubulin

      DOI: 10.1016/j.celrep.2021.108921

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  170. Mar 2021
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Towards establishing extracellular vesicle-associated RNAs as biomarkers for HER2+ breast cancer
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      RRID:AB_477582

      DOI: 10.12688/f1000research.27393.2

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  172. Feb 2021
  173. academic.oup.com academic.oup.com
    Maternal high fat diet multigenerationally impairs hippocampal synaptic plasticity and memory in male rat offspring
    2
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      RRID:AB_477582

      DOI: 10.1210/endocr/bqaa214

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      DOI: 10.1210/endocr/bqaa214

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  174. www.sciencedirect.com www.sciencedirect.com
    Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning
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    1. scibot 25 Feb 2021
      RRID:AB_477582

      DOI: 10.1016/j.celrep.2020.02.102

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    sciencedirect.com/science/article/pii/S2211124720302837
  175. www.sciencedirect.com www.sciencedirect.com
    CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition
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    1. scibot 25 Feb 2021
      RRID:AB_477582

      DOI: 10.1016/j.celrep.2021.108768

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    sciencedirect.com/science/article/pii/S2211124721000814
  176. Jan 2021
  177. link.springer.com link.springer.com
    Inhibition of p38 Mitogen–Activated Protein Kinase Ameliorates HAP40 Depletion–Induced Toxicity and Proteasomal Defect in Huntington’s Disease Model
    1
    1. scibot 28 Jan 2021
      anti-tubulin

      DOI: 10.1007/s12035-020-02280-y

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  178. www.sciencedirect.com www.sciencedirect.com
    Prolonged mitosis causes separase deregulation and chromosome nondisjunction
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      RRID:AB_477582

      DOI: 10.1016/j.celrep.2020.108652

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    sciencedirect.com/science/article/pii/S2211124720316417
  179. elifesciences.org elifesciences.org
    Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm
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      RRID:AB_477582

      DOI: 10.7554/eLife.60047

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  180. Dec 2020
  181. academic.oup.com academic.oup.com
    A ubiquitin switch controls autocatalytic inactivation of the DNA–protein crosslink repair protease SPRTN
    1
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      anti-Tubulin

      DOI: 10.1093/nar/gkaa1224

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa1224/6042962
  182. www.sciencedirect.com www.sciencedirect.com
    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions
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      RRID:AB_477582

      DOI: 10.1016/j.celrep.2020.108546

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  183. www.sciencedirect.com www.sciencedirect.com
    Ca2+ Release by IP3 Receptors Is Required to Orient the Mitotic Spindle
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      RRID:AB_477582

      DOI: 10.1016/j.celrep.2020.108483

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  184. www.mdpi.com www.mdpi.com
    Comparative Proteomics Unveils LRRFIP1 as a New Player in the DAPK1 Interactome of Neurons Exposed to Oxygen and Glucose Deprivation
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      RRID:AB_477582

      DOI: 10.3390/antiox9121202

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  185. Oct 2020
  186. www.sciencedirect.com www.sciencedirect.com
    Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner
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      RRID:AB_477582

      DOI: 10.1016/j.redox.2020.101742

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  187. Sep 2020
  188. www.sciencedirect.com www.sciencedirect.com
    Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development
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      RRID:AB_477582

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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish
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      RRID:AB_477582

      DOI: 10.7554/eLife.54935

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  190. elifesciences.org elifesciences.org
    Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs
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      RRID:AB_477582

      DOI: 10.7554/eLife.54379

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  191. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Survey of Ribosome Collision
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      RRID:AB_477582

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  192. www.sciencedirect.com www.sciencedirect.com
    FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells
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      RRID:AB_477582

      DOI: 10.1016/j.immuni.2020.04.002

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    sciencedirect.com/science/article/pii/S1074761320301606
  193. elifesciences.org elifesciences.org
    Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche
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      RRID:AB_477582

      DOI: 10.7554/eLife.42386

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  194. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of the catalytic subunit of DNA‐dependent protein kinase (DNA‐PKcs) stimulates osteoblastogenesis by potentiating bone morphogenetic protein 2 (BMP2) responses
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      RRID:AB_477582

      DOI: 10.1002/jcp.29927

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  195. www.sciencedirect.com www.sciencedirect.com
    Ensemble-Level Organization of Human Kinetochores and Evidence for Distinct Tension and Attachment Sensors
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    1. scibot 07 Sep 2020
      RRID:AB_477582

      DOI: 10.1016/j.celrep.2020.107535

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  196. www.eneuro.org www.eneuro.org
    Functional Assessment In Vivo of the Mouse Homologue of the Human Ala-9-Ser NHE6 Variant
    1
    1. scibot 04 Sep 2020
      RRID:AB_477582

      DOI: 10.1523/ENEURO.0046-19.2019

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    eneuro.org/content/6/6/ENEURO.0046-19.2019
  197. link.springer.com link.springer.com
    Cognitive Decline and Modulation of Alzheimer’s Disease-Related Genes After Inhibition of MicroRNA-101 in Mouse Hippocampal Neurons
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      RRID:AB_477582

      DOI: 10.1007/s12035-020-01957-8

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    link.springer.com/article/10.1007/s12035-020-01957-8
  198. www.nature.com www.nature.com
    C9orf72 in myeloid cells suppresses STING-induced inflammation
    1
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      tubulin

      DOI: 10.1038/s41586-020-2625-x

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  199. link.springer.com link.springer.com
    Combining the lack of chromogranins with chronic L-DOPA treatment affects motor activity in mice
    1
    1. scibot 03 Sep 2020
      actin

      DOI: 10.1007/s00441-019-03159-8

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  200. Jan 2020
  201. www.sciencedirect.com www.sciencedirect.com
    Translational Regulation of Non-autonomous Mitochondrial Stress Response Promotes Longevity
    1
    1. scibot 13 Jan 2020
      RRID:AB_477582

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    Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring
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    NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus
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