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    ARF alters PAF1 complex integrity to selectively repress oncogenic transcription programs upon p53 loss
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    Autophagy-dependent splicing control directs translation toward inflammation during senescence
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  4. Nov 2024
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    Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis
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    Residue Y362 is crucial for FLIPL to impart catalytic activity to pro-caspase-8 to suppress necroptosis
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  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted Deletion of Fibroblast Growth Factor 23 Rescues Metabolic Dysregulation of Diet-induced Obesity in Female Mice
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    Non-autophagic Golgi-LC3 lipidation facilitates TFE3 stress response against Golgi dysfunction
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    pmc.ncbi.nlm.nih.gov/articles/PMC11535212/
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    Reduced mesencephalic astrocyte-derived neurotrophic factor ... : Neural Regeneration Research
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      DOI: 10.4103/NRR.NRR-D-23-01666

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  10. Oct 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
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  12. Sep 2024
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    SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
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    NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation
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    Critical role of Syk-dependent STAT1 activation in innate antiviral immunity
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    sciencedirect.com/science/article/pii/S2211124720316168
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    RAD52 Adjusts Repair of Single-Strand Breaks via Reducing DNA-Damage-Promoted XRCC1/LIG3α Co-localization
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    sciencedirect.com/science/article/pii/S2211124720316144
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    Exosomal miR-193a and let-7g accelerate cancer progression on primary colorectal cancer and paired peritoneal metastatic cancer
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    Hormonal Regulation of Autophagy in Thyroid PCCL3 Cells and the Thyroids of Male Mice
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  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GLAST‐CreERT2 mediated deletion of GDNF increases brain damage and exacerbates long‐term stroke outcomes after focal ischemic stroke in mouse model
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      DOI: 10.1002/glia.23848

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    Constitutive CHK1 expression drives a pSTAT3-CIP2A circuit that promotes glioblastoma cell survival and growth
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    Inhibition of transcription factor SP1 produces neuroprotective effects through decreasing MAO B activity in MPTP/MPP+ Parkinson's disease models
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      DOI: 10.1002/jnr.24266

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    Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer
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    Multi-omics analysis using antibody-based in situ biotinylation technique suggests the mechanism of Cajal body formation
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    ZG16 enhances the maturation of dendritic cells via induction of CD40 and contributes to the antitumor immunity in pancreatic cancer
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      DOI: 10.1038/s41388-024-03154-6

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    The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization
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    Glioblastoma mesenchymal subtype enhances antioxidant defence to reduce susceptibility to ferroptosis
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    FYVE1/FREE1 is involved in glutamine-responsive TORC1 activation in plants
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    Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity
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    Osteocalcin-expressing neutrophils from skull bone marrow exert immunosuppressive and neuroprotective effects after TBI
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  30. Aug 2024
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    BBOX1 mediates metabolic reprogramming driven by hypoxia and participates in the malignant progress of high-grade serous ovarian cancer
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    RNA interacts with topoisomerase I to adjust DNA topology
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    TRIM24 upregulates ORM2 to alleviate abnormal lipid metabolism, inflammation, and oxidative stress in mice with obstructive sleep apnea syndrome & metabolic dysfunction-associated steatotic liver disease
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    Circulating extracellular microRNAs in the blood promote sociability in mice
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    biorxiv.org/content/10.1101/2024.08.12.605506v1
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    Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
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    cell.com/cell-metabolism/fulltext/S1550-4131(24)00285-7
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    Roles of PINK1 in regulation of systemic growth inhibition induced by mutations of PTEN in Drosophila
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    Reorganization of H3K9me heterochromatin leads to neuronal impairment via the cascading destruction of the KDM3B-centered epigenomic network
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      DOI: 10.1016/j.isci.2024.110380

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  38. www.tandfonline.com www.tandfonline.com
    Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer’s disease
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      sc-47,778, 1:2000 dilutions, from Santa Cruz

      DOI: 10.1080/01616412.2021.1893566

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  39. academic.oup.com academic.oup.com
    The extract of Ilex kudingcha inhibits atherosclerosis in apoE-deficient mice by suppressing cholesterol accumulation in macrophages
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      DOI: 10.1093/bbb/zbab140

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    academic.oup.com/bbb/advance-article-abstract/doi/10.1093/bbb/zbab140/6346599
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Localization of α‐Synuclein in Teleost Central Nervous System: Immunohistochemical and Western Blot Evidence by 3D5 Monoclonal Antibody in the Common Carp, Cyprinus carpio
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      DOI: 10.1002/cne.23722

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  41. Jul 2024
  42. www.sciencedirect.com www.sciencedirect.com
    Blending and separating dynamics of RNA-binding proteins develop architectural splicing networks spreading throughout the nucleus
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    sciencedirect.com/science/article/pii/S1097276524005446
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    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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    sciencedirect.com/science/article/pii/S2589004224015013
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway
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      DOI: 10.1111/acel.14258

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    The canonical antiviral protein oligoadenylate synthetase 1 elicits antibacterial functions by enhancing IRF1 translation
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    CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection
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    Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
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    Small molecule inhibitor binds to NOD-like receptor family pyrin domain containing 3 and prevents inflammasome activation
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    Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle
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    Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers
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    DNA break induces rapid transcription repression mediated by proteasome-dependent RNAPII removal
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  57. Jun 2024
  58. www.cell.com www.cell.com
    Chemotherapy-induced intestinal epithelial damage directly promotes galectin-9-driven modulation of T cell behavior
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    Cdk5 inhibition in the SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis suppresses neurodegeneration and extends survival
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    Protein-energy restriction-induced lipid metabolism disruption causes stable-to-progressive disease shift in Mycobacterium avium-infected female mice
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    Intergenic risk variant rs56258221 skews the fate of naive CD4+ T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis
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    Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression
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    Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8
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  67. 52.53.155.43 52.53.155.43
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  68. 52.53.155.43 52.53.155.43
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  69. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia
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    Everolimus exerts anticancer effects through inhibiting the interaction of matrix metalloproteinase-7 with syndecan-2 in colon cancer cells
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    Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals
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    Hypoxia modulates P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) drug transporters in brain endothelial cells of the developing human blood-brain barrier
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  77. Apr 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
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    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
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    Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition
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  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation
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    BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children
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    A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
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    OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion
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    Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes
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    Alistipes indistinctus-derived hippuric acid promotes intestinal urate excretion to alleviate hyperuricemia
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    Liver Androgen Receptor Knockout Improved High-fat Diet Induced Glucose Dysregulation in Female Mice But Not Male Mice
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    Fluoroquinolones upregulate insulin-like growth factor–binding protein 3, inhibit cell growth and insulin-like growth factor signaling
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    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    Alistipes indistinctus-derived hippuric acid promotes intestinal urate excretion to alleviate hyperuricemia
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    Search for Chromosomal Instability aiding Variants (CIVa) reveal naturally occurring kinetochore gene variants that perturb chromosome segregation
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway
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    Differential effect of cancer-associated fibroblast-derived extracellular vesicles on cisplatin resistance in oral squamous cell carcinoma via miR-876-3p
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  122. Dec 2023
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    Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
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    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    TRPC4 deletion elicits behavioral defects in sociability by dysregulating expression of microRNA-138-2
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    Potential therapeutic implications of histidine catabolism by the gut microbiota in NAFLD patients with morbid obesity
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  131. Nov 2023
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    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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    Macrophage autophagy deficiency-induced CEBPB accumulation alleviates atopic dermatitis via impairing M2 polarization
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serotonin receptor subtype-2B signaling is associated with interleukin-18-induced cardiomyoblast hypertrophy in vitro
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    Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder
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  168. Jul 2023
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    Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy
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    Endogenous anti-tumorigenic nitro-fatty acids inhibit the ubiquitin-proteasome system by directly targeting the 26S proteasome
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    Targeted removal of macrophage-secreted interleukin-1 receptor antagonist protects against lethal Candida albicans sepsis
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    Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism
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    Silencing of CDC42 inhibits contraction and growth-related functions in prostate stromal cells, which is mimicked by ML141
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    Expression patterns of AEG-1 in the normal brain
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    Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas
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    The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2
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    Mechanisms of insertions at a DNA double-strand break
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    Muscle glycome in Idiopathic Inflammatory Myopathies: impact in IL-6 production and disease prognosis.
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    Two parallel medial prefrontal cortex-amygdala pathways mediate memory deficits via glutamatergic projection in surgery mice
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    SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux
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    Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal
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    Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancer
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    Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression
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    Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes
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    MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance
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    SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury
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    Hypoxia modulates P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) drug transporters in brain endothelial cells of the developing human blood-brain barrier
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    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
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    Modeling breast cancer proliferation, drug synergies, and alternating therapies
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    Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response
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    MYO10 regulates genome stability and cancer inflammation through mediating mitosis
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    Deubiquitinase USP1 influences the dedifferentiation of mouse pancreatic β-cells
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    Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models
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    Inhibition of growth and contraction in human prostate stromal cells by silencing of NUAK1 and -2, and by the presumed NUAK inhibitors HTH01-015 and WZ4003
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    Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer
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    Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis
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    Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter
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    Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment.
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    Regulation of sertoli cell function by planar cell polarity (PCP) protein Fjx1
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    Piezo1 induces endothelial responses to shear stress via soluble adenylyl Cyclase-IP3R2 circuit
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    DNA-initiated epigenetic cascades driven by C9orf72 hexanucleotide repeat
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    Higher replication potential of West Nile virus governs apoptosis induction in human neuroblastoma cells
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      DOI: 10.1007/s10495-023-01844-2

      Resource: (Santa Cruz Biotechnology Cat# sc-47778, RRID:AB_626632)

      Curator: @scibot

      SciCrunch record: RRID:AB_626632

      What is this?
      RRID:AB_626632
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    link.springer.com/article/10.1007/s10495-023-01844-2