352 Matching Annotations
  1. Last 7 days
  2. www.cell.com www.cell.com
    Formate promotes invasion and metastasis in reliance on lipid metabolism
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    1. scibot 23 Nov 2024
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      DOI: 10.1016/j.celrep.2023.113034

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    cell.com/cell-reports/abstract/S2211-1247(23)01045-8
  3. Oct 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1158/1535-7163.MCT-23-0564

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    ncbi.nlm.nih.gov/pmc/articles/PMC11443213/
  5. Sep 2024
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A biallelic mutation in CACNA2D2 associated with developmental and epileptic encephalopathy affects calcium channel-dependent as well as synaptic functions of α2δ-2
    1
    1. scibot 27 Sep 2024
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      DOI: 10.1111/jnc.16197

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16197
  7. www.sciencedirect.com www.sciencedirect.com
    A tripartite circRNA/mRNA/miRNA interaction regulates glutamatergic signaling in the mouse brain
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    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114766

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    sciencedirect.com/science/article/pii/S2211124724011173
  8. www.sciencedirect.com www.sciencedirect.com
    Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer
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    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114751

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    sciencedirect.com/science/article/pii/S2211124724011021
  9. Aug 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tau‐mediated synaptic dysfunction is coupled with HCN channelopathy
    1
    1. scibot 30 Aug 2024
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      DOI: 10.1002/alz.14074

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    ncbi.nlm.nih.gov/pmc/articles/PMC11350046/
  11. journals.plos.org journals.plos.org
    The conformational plasticity of structurally unrelated lipid transport proteins correlates with their mode of action
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    1. scibot 23 Aug 2024
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      DOI: 10.1371/journal.pbio.3002737

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    journals.plos.org/plosbiology/article
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small GTPase ActIvitY ANalyzing (SAIYAN) system: A method to detect GTPase activation in living cells
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    1. scibot 20 Aug 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11303508/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adaptive changes in group-II metabotropic glutamate receptors underlie the deficit in recognition memory induced by methamphetamine in mice
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    1. scibot 19 Aug 2024
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      DOI: 10.1523/ENEURO.0523-23.2024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11298959/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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    1. scibot 18 Aug 2024
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      DOI: 10.3389/fonc.2024.1431362

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    ncbi.nlm.nih.gov/pmc/articles/PMC11291216/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)
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    1. scibot 02 Aug 2024
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      DOI: 10.1038/s41408-021-00603-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC8752621/
  16. journals.physiology.org journals.physiology.org
    Alamandine enhances cardiomyocyte contractility in hypertensive rats through a nitric oxide-dependent activation of CaMKII | American Journal of Physiology-Cell Physiology
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    1. scibot 02 Aug 2024
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      DOI: 10.1152/ajpcell.00153.2019

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    journals.physiology.org/doi/full/10.1152/ajpcell.00153.2019
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex
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    1. scibot 02 Aug 2024
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      DOI: 10.1002/cne.23691

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    onlinelibrary.wiley.com/doi/10.1002/cne.23691/full
  18. www.mdpi.com www.mdpi.com
    A Novel Monoclonal Antibody Targeting Cancer-Specific Plectin Has Potent Antitumor Activity in Ovarian Cancer
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    1. scibot 02 Aug 2024
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      DOI: 10.3390/cells10092218

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    mdpi.com/2073-4409/10/9/2218/htm
  19. 52.53.155.43 52.53.155.43
    Supplemental_Materials (1)-html.html
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    1. scibot 02 Aug 2024
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      DOI: 10.2337/figshare.21183496

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    52.53.155.43/d88ad76d933f2aaeca09b3b316a302f76c99bbf1/Supplemental_Materials (1)-html.html
  20. Jul 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of small molecule inhibitors of G3BP-driven stress granule formation
    1
    1. scibot 30 Jul 2024
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      DOI: 10.1083/jcb.202308083

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    ncbi.nlm.nih.gov/pmc/articles/PMC10824102/
  22. www.sciencedirect.com www.sciencedirect.com
    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
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    1. scibot 17 Jul 2024
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    sciencedirect.com/science/article/pii/S1097276524005306
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effects of non-rapid eye movement sleep on the cortical synaptic expression of GluA1-containing AMPA receptors
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    1. scibot 16 Jul 2024
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      DOI: 10.1111/ejn.16460

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    onlinelibrary.wiley.com/doi/10.1111/ejn.16460
  24. www.sciencedirect.com www.sciencedirect.com
    Chimeric antigen receptor-induced antigen loss protects CD5.CART cells from fratricide without compromising on-target cytotoxicity
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    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101628

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    sciencedirect.com/science/article/pii/S266637912400332X
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preventing loss of sirt1 lowers mitochondrial oxidative stress and preserves c2c12 myotube diameter in an in vitro model of cancer cachexia
    1
    1. scibot 04 Jul 2024
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      DOI: 10.14814/phy2.16103

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    ncbi.nlm.nih.gov/pmc/articles/PMC11215470/
  26. Jun 2024
  27. link.springer.com link.springer.com
    β-Carboline derivatives are potent against Acute Myeloid Leukemia in vitro and in vivo
    1
    1. scibot 28 Jun 2024
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      DOI: 10.1007/s43440-024-00614-4

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    link.springer.com/article/10.1007/s43440-024-00614-4
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Desmosomal Cadherin Tension Loss in Pemphigus Vulgaris Mediated by the Inhibition of Active RhoA at Cell-Cell Adhesions
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    1. scibot 21 Jun 2024
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      DOI: 10.1101/2024.05.03.592394

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100601/
  29. May 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids
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    1. scibot 16 May 2024
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      DOI: 10.1016/j.stem.2024.04.019

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    sciencedirect.com/science/article/pii/S1934590924001462
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATG9B regulates bacterial internalization via actin rearrangement
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    1. scibot 05 May 2024
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      DOI: 10.1016/j.isci.2024.109623

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    ncbi.nlm.nih.gov/pmc/articles/PMC11066431/
  32. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
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    1. scibot 04 May 2024
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      DOI: 10.1101/2024.01.21.576568

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    52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
  33. Apr 2024
  34. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114163

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    sciencedirect.com/science/article/pii/S2211124724004911
  35. www.sciencedirect.com www.sciencedirect.com
    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
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    1. scibot 24 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114144

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    sciencedirect.com/science/article/pii/S2211124724004728
  36. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Pim kinases triggers a broad antiviral activity by affecting innate immunity and via the PI3K-Akt-mTOR axis the endolysosomal system
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    1. scibot 23 Apr 2024
      Santa Cruz Biotechnology, sc-32233

      DOI: 10.1016/j.antiviral.2024.105891

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    sciencedirect.com/science/article/pii/S0166354224001001
  37. www.sciencedirect.com www.sciencedirect.com
    Necrosulfonamide causes oxidation of PCM1 and impairs ciliogenesis and autophagy
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    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.isci.2024.109580

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    sciencedirect.com/science/article/pii/S2589004224008022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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    1. scibot 03 Apr 2024
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      DOI: 10.1158/1078-0432.CCR-23-1003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
  39. Mar 2024
  40. link.springer.com link.springer.com
    Transcriptional and metabolic effects of aspartate-glutamate carrier isoform 1 (AGC1) downregulation in mouse oligodendrocyte precursor cells (OPCs)
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    1. scibot 30 Mar 2024
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      DOI: 10.1186/s11658-024-00563-z

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    link.springer.com/article/10.1186/s11658-024-00563-z
  41. www.sciencedirect.com www.sciencedirect.com
    ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition
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    sciencedirect.com/science/article/pii/S2211124724003231
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eukaryotic release factor 1 from Euplotes promotes frameshifting at premature stop codons in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952039/
  43. www.sciencedirect.com www.sciencedirect.com
    Dual-specificity tyrosine-regulated kinase 2 exerts anti-tumor effects by induction of G1 arrest in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S0304416524000436
  44. www.sciencedirect.com www.sciencedirect.com
    Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons
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    sciencedirect.com/science/article/pii/S2211124724002328
  45. www.sciencedirect.com www.sciencedirect.com
    AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway
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    sciencedirect.com/science/article/pii/S0925443924001054
  46. www.sciencedirect.com www.sciencedirect.com
    Alternative splicing decouples local from global PRC2 activity
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      DOI: 10.1016/j.molcel.2024.02.011

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    sciencedirect.com/science/article/pii/S1097276524001308
  47. www.sciencedirect.com www.sciencedirect.com
    HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity
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      DOI: 10.1016/j.celrep.2024.113870

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    sciencedirect.com/science/article/pii/S2211124724001980
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    Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cells
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  49. Feb 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTBP3/IGF2BP3/HMGA1 axis promotes renal cancer growth and metastasis
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    The Mas agonist CGEN-856S prevents Ang II induced cardiomyocyte hypertrophy via nitric oxide production
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    Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1
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    De novo variants in DENND5B cause a neurodevelopmental disorder
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    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
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    Metabolic rewiring and autophagy inhibition correct lysosomal storage disease in Mucopolysaccharidosis IIIB
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    Protocol for gene knockdown using siRNA in primary cultured neonatal murine microglia
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    Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity
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    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
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  59. Jan 2024
  60. 52.53.155.43 52.53.155.43
    Kisspeptin Regulates Cell Invasion and Migration in Endometrial Cancer
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    Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo
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  62. Dec 2023
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    Lysoglycosphingolipids have the ability to induce cell death through direct PI3K inhibition
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  64. Nov 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Postnatal Development and Maintenance of Functional Pituitary Gonadotrophs is Dependent on PI4-kinase A
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    MFGE-8 identified in fetal mesenchymal-stromal-cell-derived exosomes ameliorates acute hepatic failure pathology
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  67. Oct 2023
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    PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors
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    Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination
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    CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer
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  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
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    Oleanolic acid alleviates the extrapyramidal symptoms and cognitive impairment induced by haloperidol through the striatal PKA signaling pathway in mice
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    ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms
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    Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer
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  75. Sep 2023
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    An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis
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    Acetylation reprograms MITF target selectivity and residence time
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    Argatroban promotes recovery of spinal cord injury by inhibiting the PAR1/JAK2/STAT3 signaling pathway
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  79. Aug 2023
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    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
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    Senescent cells form nuclear foci that contain the 26S proteasome
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    Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2
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  84. Jul 2023
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    Thymine DNA glycosylase regulates cell-cycle-driven p53 transcriptional control in pluripotent cells
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    Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury
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    Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
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  88. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
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  89. www.sciencedirect.com www.sciencedirect.com
    Functional viromic screens uncover regulatory RNA elements
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    Genome-wide CRISPR-Cas9 screen analyzed by SLIDER identifies network of repressor complexes that regulate TRIM24
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    Alcohol Clin Exp Res - 2023 - Shanmugam - Ethanol inhibition of undifferentiated rat neural progenitor cell replication-html.html
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    A chimeric human/dog-DNA vaccine against CSPG4 induces immunity with therapeutic potential in comparative preclinical models of osteosarcoma
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  93. Jun 2023
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    Generation of two edited iPSCs lines by CRISPR/Cas9 with point mutations in PKP2 gene for Arrhythmogenic Cardiomyopathy in vitro modeling
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    Overcoming MET-mediated resistance in oncogene-driven NSCLC
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    SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
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    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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    Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation
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    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response
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    Exercise Improves Orofacial Pain and Modifies Neuropeptide Expression in a Rat Model of Parkinson’s Disease
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    eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance
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    Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter
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    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations
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    Molecular mechanisms of stress-induced reactivation in mumps virus condensates
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    Conformational dynamics of lipid transfer domains provide a general framework to decode their functional mechanism
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    Clinical Consequences and Functional Impact of the Rare S737F CFTR Variant and Its Responsiveness to CFTR Modulators
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    An Overview of Alamadine/MrgD Signaling and Its Role in Cardiomyocytes
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  113. journals.physiology.org journals.physiology.org
    An overview of alamadine/MrgD signaling and its role in cardiomyocytes
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    Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis
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    The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome
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  116. Mar 2023
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    A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses
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    GRHL2 and AP2a coordinate early surface ectoderm lineage commitment during development
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  119. Feb 2023
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    Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes
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    Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
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  123. Jan 2023
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    Identification of key microRNAs regulating ELOVL6 and glioblastoma tumorigenesis
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    A KO mouse model for the lncRNA Lhx1os produces motor neuron alterations and locomotor impairment
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    Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
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    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
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    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
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    Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation
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  133. aacrjournals.org aacrjournals.org
    Loss of epigenetic regulation disrupts lineage integrity, induces aberrant alveogenesis and promotes breast cancer
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  134. Nov 2022
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells
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    A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner
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  138. Oct 2022
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    Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice
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    PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the CORB GTPase domain
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    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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    Human-specific regulation of neural maturation identified by cross-primate transcriptomics
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  143. www.nature.com www.nature.com
    C9orf72 functions in the nucleus to regulate DNA damage repair
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      DOI: 10.1038/s41418-022-01074-0

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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
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  145. Sep 2022
  146. www.sciencedirect.com www.sciencedirect.com
    Hepatic ER stress suppresses adipose browning through ATF4-CIRP-ANGPTL3 cascade
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    CDK14 inhibition reduces mammary stem cell activity and suppresses triple negative breast cancer progression
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  148. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Peripheral and respiratory muscle impairment during murine acute lung injury
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  149. Aug 2022
  150. www.sciencedirect.com www.sciencedirect.com
    ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assessment of Androgen Receptor splice variant-7 as a biomarker of clinical response in castration-sensitive prostate cancer
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    Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
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    Discovery of compounds that reactivate p53 mutants in vitro and in vivo
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    sciencedirect.com/science/article/pii/S2451945622002756
  155. Jul 2022
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    High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition
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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T-cell dysfunction upon expression of MYC with altered phosphorylation at Threonine 58 and Serine 62
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    Src activation in lipid rafts confers epithelial cells with invasive potential to escape from apical extrusion during cell competition
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  159. www.sciencedirect.com www.sciencedirect.com
    Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer’s disease
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    Generation of hematopoietic lineage cell-specific chimeric mice using retrovirus-transduced fetal liver cells
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  161. Jun 2022
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    Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement
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  163. www.sciencedirect.com www.sciencedirect.com
    Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine
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    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
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  165. May 2022
  166. www.sciencedirect.com www.sciencedirect.com
    ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
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    XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
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    Functional Interaction Between the Oncogenic Kinase NEK2 and Sam68 Promotes a Splicing Program Involved in Migration and Invasion in Triple-Negative Breast Cancer
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      DOI: 10.3389/fonc.2022.880654

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  169. www.sciencedirect.com www.sciencedirect.com
    SETD4-mediated KU70 methylation suppresses apoptosis
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    Excitation–Contraction Coupling: Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1.1
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  171. Apr 2022
  172. www.sciencedirect.com www.sciencedirect.com
    The role of PTEN in primary sensory neurons in processing itch and thermal information in mice
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    Centrosome-dependent microtubule modifications set the conditions for axon formation
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    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
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    Mitigating Effect of Estrogen in Alzheimer’s Disease-Mimicking Cerebral Organoid
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      DOI: 10.3389/fnins.2022.816174

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    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
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  177. Mar 2022
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    The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs
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    Pathogen size alters C-type lectin receptor signaling in dendritic cells to influence CD4 Th9 cell differentiation
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    Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis
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    Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling
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  182. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Aggravation of pulmonary fibrosis after knocking down the aryl hydrocarbon receptor in the insulin-like growth factor 1 receptor pathway
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  183. Feb 2022
  184. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Coronin 1A facilitates calcium mobilization and promotes astrocyte reactivity in HIV-1 neuropathogenesis
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice
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  186. academic.oup.com academic.oup.com
    Growth hormone-induced STAT5B regulates Star gene expression through a cooperation with cJUN in mouse MA-10 Leydig cells
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      DOI: 10.1210/endocr/bqab267

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    academic.oup.com/endo/article/163/2/bqab267/6490116
  187. Jan 2022
  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency
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  189. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A new therapeutic effect of fenofibrate in Duchenne muscular dystrophy: The promotion of myostatin degradation
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      DOI: 10.1111/bph.15678

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    Cas11 enables genome engineering in human cells with compact CRISPR-Cas3 systems
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    Identification of a dihydropyridine scaffold that blocks ryanodine receptors
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  192. www.sciencedirect.com www.sciencedirect.com
    Lipid droplet dynamics regulate adult muscle stem cell fate
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  193. Dec 2021
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    Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1
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    GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway
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    Methods to separate nuclear soluble fractions reflecting localizations in living cells
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  197. Nov 2021
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    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
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  199. www.sciencedirect.com www.sciencedirect.com
    SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase
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  200. Oct 2021
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    Homeostatic plasticity induced by increased acetylcholine release at the mouse neuromuscular junction.
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    Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2
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    ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells
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    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
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    Cancer cell immune mimicry delineates onco-immunologic modulation
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  206. Sep 2021
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    FKBP51 Affects TNF-Related Apoptosis Inducing Ligand Response in Melanoma
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    Complement Factor B Mediates Ocular Angiogenesis through Regulating the VEGF Signaling Pathway
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    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
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    Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species
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    Activating a collaborative innate-adaptive immune response to control metastasis
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    FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease
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  213. Aug 2021
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    Metabolic plasticity drives development during mammalian embryogenesis
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    Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
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    Identification of novel genes and pathways regulated by the orphan nuclear receptor COUP-TFII in mouse MA-10 Leydig cells†
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    Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models
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    Fisetin provides antidepressant effects by activating the TrkB signal pathway in mice
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    Acetylation of Cytidine in mRNA Promotes Translation Efficiency
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  223. Jul 2021
  224. elifesciences.org elifesciences.org
    KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia
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      SC-32233

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    Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay
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      GAPDH

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    The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins
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      GAPDH (mouse, monoclonal)

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    Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells
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      Mouse GAPDH

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    Inhibition of Hsp70 Suppresses Neuronal Hyperexcitability and Attenuates Epilepsy by Enhancing A-Type Potassium Current
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  231. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Oral administration of a new HRI activator as a new strategy to improve high‐fat‐diet‐induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21
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      GAPDH

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