544 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
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    1. scibot 17 Nov 2024
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      DOI: 10.1016/j.molcel.2024.10.016

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    sciencedirect.com/science/article/pii/S1097276524008566
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen
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    1. scibot 14 Nov 2024
      RRID:AB_772210

      DOI: 10.7554/eLife.89606

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    pmc.ncbi.nlm.nih.gov/articles/PMC11556787/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance
    1
    1. scibot 10 Nov 2024
      RRID:AB_772210

      DOI: 10.1016/j.isci.2024.111139

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    pmc.ncbi.nlm.nih.gov/articles/PMC11539641/
  5. Sep 2024
  6. www.sciencedirect.com www.sciencedirect.com
    C9orf72 poly-PR forms anisotropic condensates causative of nuclear TDP-43 pathology
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.isci.2024.110937

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    sciencedirect.com/science/article/pii/S258900422402162X
  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synaptotagmin‐7 enhances calcium‐sensing of chromaffin cell granules and slows discharge of granule cargos
    1
    1. scibot 25 Sep 2024
      RRID:AB_2721110

      DOI: 10.1111/jnc.14986

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14986
  8. academic.oup.com academic.oup.com
    Ghrelin-Induced Sodium Reabsorption is Mediated by PKA and Microtubule-Dependent αE Na C Translocation In Female Rats
    2
    1. scibot 25 Sep 2024
      RRID:AB_772206

      DOI: 10.1210/js.2019-00121

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    2. scibot 25 Sep 2024
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      DOI: 10.1210/js.2019-00121

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    academic.oup.com/jes/article/3/11/2088/5556717
  9. www.sciencedirect.com www.sciencedirect.com
    Dynamic allostery drives autocrine and paracrine TGF-β signaling
    1
    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  10. www.sciencedirect.com www.sciencedirect.com
    FYVE1/FREE1 is involved in glutamine-responsive TORC1 activation in plants
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.isci.2024.110814

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    sciencedirect.com/science/article/pii/S258900422402039X
  11. www.sciencedirect.com www.sciencedirect.com
    Multiple direct and indirect roles of the Paf1 complex in transcription elongation, splicing, and histone modifications
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114730

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    sciencedirect.com/science/article/pii/S2211124724010817
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    The ribosome collision sensor Hel2 functions as preventive quality control in the secretory pathway
    1
    1. scibot 09 Sep 2024
      RRID:AB_772210

      DOI: 10.1016/j.celrep.2021.108877

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    sciencedirect.com/science/article/pii/S2211124721001911
  13. www.sciencedirect.com www.sciencedirect.com
    Disorder-mediated interactions target proteins to specific condensates
    1
    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.molcel.2024.08.017

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    sciencedirect.com/science/article/pii/S1097276524006713
  14. Aug 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume
    1
    1. scibot 30 Aug 2024
      RRID:AB_772210

      DOI: 10.1371/journal.pone.0309461

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    ncbi.nlm.nih.gov/pmc/articles/PMC11356391/
  16. www.sciencedirect.com www.sciencedirect.com
    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
    1
    1. scibot 27 Aug 2024
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      DOI: 10.1016/j.neuron.2024.07.025

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    sciencedirect.com/science/article/pii/S0896627324005701
  17. www.sciencedirect.com www.sciencedirect.com
    Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function
    1
    1. scibot 27 Aug 2024
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      DOI: 10.1016/j.chembiol.2024.07.017

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    sciencedirect.com/science/article/pii/S2451945624003192
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II
    1
    1. scibot 26 Aug 2024
      RRID:AB_772210

      DOI: 10.7554/eLife.94407

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    ncbi.nlm.nih.gov/pmc/articles/PMC11343564/
  19. www.biorxiv.org www.biorxiv.org
    Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy
    1
    1. scibot 18 Aug 2024
      RRID:AB_772210

      DOI: 10.1101/2024.07.31.605623

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    biorxiv.org/content/10.1101/2024.07.31.605623v1
  20. www.cell.com www.cell.com
    Differential effect of asparagine and glutamine removal on three adenocarcinoma cell lines
    1
    1. scibot 18 Aug 2024
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      DOI: 10.1016/j.heliyon.2024.e35789

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    cell.com/heliyon/fulltext/S2405-8440(24)11820-8
  21. link.springer.com link.springer.com
    Exclusive Characteristics of the p.E555K Dominant-Negative Variant in Autosomal Dominant E47 Deficiency
    1
    1. scibot 01 Aug 2024
      RRID:AB_772210

      DOI: 10.1007/s10875-024-01758-x

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    link.springer.com/article/10.1007/s10875-024-01758-x
  22. Jul 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals
    1
    1. scibot 27 Jul 2024
      RRID:AB_772210

      DOI: 10.1038/s41598-024-67570-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11269720/
  24. www.sciencedirect.com www.sciencedirect.com
    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
    1
    1. scibot 26 Jul 2024
      AB_772210

      DOI: 10.1016/j.celrep.2024.114473

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    sciencedirect.com/science/article/pii/S2211124724008027
  25. www.sciencedirect.com www.sciencedirect.com
    Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114496

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    sciencedirect.com/science/article/pii/S2211124724008258
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Secondary interactions in ubiquitin-binding domains achieve linkage or substrate specificity
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114545

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    ncbi.nlm.nih.gov/pmc/articles/PMC11372445/
  27. www.cell.com www.cell.com
    Disruption of TGF-β signaling pathway is required to mediate effective killing of hepatocellular carcinoma by human iPSC-derived NK cells
    2
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.stem.2024.06.009

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    2. scibot 19 Jul 2024
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      DOI: 10.1016/j.stem.2024.06.009

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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00217-0
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dystrophin S3059 phosphorylation partially attenuates denervation atrophy in mouse tibialis anterior muscles
    1
    1. scibot 17 Jul 2024
      RRID:AB_772210

      DOI: 10.14814/phy2.16145

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    ncbi.nlm.nih.gov/pmc/articles/PMC11245571/
  29. www.sciencedirect.com www.sciencedirect.com
    Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114448

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    sciencedirect.com/science/article/pii/S2211124724007770
  30. www.biorxiv.org www.biorxiv.org
    Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain
    1
    1. scibot 04 Jul 2024
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      DOI: 10.1101/2024.06.24.600539

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    biorxiv.org/content/10.1101/2024.06.24.600539v1
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and characterization of inducible KRAB-dCas9 iPSCs from primates for cross-species CRISPRi
    1
    1. scibot 01 Jul 2024
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      DOI: 10.1016/j.isci.2024.110090

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    ncbi.nlm.nih.gov/pmc/articles/PMC11214527/
  32. Jun 2024
  33. www.sciencedirect.com www.sciencedirect.com
    MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.017

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    sciencedirect.com/science/article/pii/S0092867424005269
  34. www.sciencedirect.com www.sciencedirect.com
    Intranasal SARS-CoV-2 Omicron variant vaccines elicit humoral and cellular mucosal immunity in female mice
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.ebiom.2024.105185

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    sciencedirect.com/science/article/pii/S2352396424002202
  35. May 2024
  36. www.cell.com www.cell.com
    1-s2.0-S2589004224013701-main-html.html
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    1. scibot 31 May 2024
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      DOI: 10.1016/j.isci.2024.110145

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    cell.com/iscience/abstract/S2589-0042(24)01370-1
  37. www.sciencedirect.com www.sciencedirect.com
    RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly
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    1. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.042

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    sciencedirect.com/science/article/pii/S0092867424004689
  38. www.sciencedirect.com www.sciencedirect.com
    Specificity profiling of deubiquitylases against endogenously generated ubiquitin-protein conjugates
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    1. scibot 30 May 2024
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      DOI: 10.1016/j.chembiol.2024.05.001

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      DOI: 10.1016/j.chembiol.2024.05.001

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    sciencedirect.com/science/article/pii/S2451945624001806
  39. www.sciencedirect.com www.sciencedirect.com
    A conserved site on Ndc80 complex facilitates dynamic recruitment of Mps1 to yeast kinetochores to promote accurate chromosome segregation
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.cub.2024.04.054

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    sciencedirect.com/science/article/pii/S0960982224005281
  40. www.sciencedirect.com www.sciencedirect.com
    Microtubule end-on attachment maturation regulates Mps1 association with its kinetochore receptor
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.cub.2024.03.062

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    sciencedirect.com/science/article/pii/S0960982224004020
  41. www.sciencedirect.com www.sciencedirect.com
    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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    1. scibot 14 May 2024
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      DOI: 10.1016/j.immuni.2024.04.016

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    sciencedirect.com/science/article/pii/S1074761324002218
  42. www.sciencedirect.com www.sciencedirect.com
    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
    1
    1. scibot 07 May 2024
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      DOI: 10.1016/j.molcel.2024.04.007

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    sciencedirect.com/science/article/pii/S1097276524002855
  43. www.mdpi.com www.mdpi.com
    IL17A Suppresses IGFBP1 in Human Endometrial Stromal Cells
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    1. scibot 03 May 2024
      RRID:AB_772210

      DOI: 10.3390/reprodmed5020006

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    mdpi.com/2673-3897/5/2/6
  44. Apr 2024
  45. www.sciencedirect.com www.sciencedirect.com
    HSV-1 employs UL56 to antagonize expression and function of cGAMP channels
    1
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      DOI: 10.1016/j.celrep.2024.114122

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    Reversible S-nitrosylation of bZIP67 by peroxiredoxin IIE activity and nitro-fatty acids regulates the plant lipid profile
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    RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRPA5 encodes a thermosensitive ankyrin ion channel receptor in a triatomine insect
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    Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
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    A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
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    BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing
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    A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
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    Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes
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    DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity
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    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
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    TREX2 deficiency suppresses spontaneous and genotoxin-associated mutagenesis
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    SARS-CoV-2 targets ribosomal RNA biogenesis
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  60. Feb 2024
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    Aberrant cortex contractions impact mammalian oocyte quality
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    Circadian Disruption across Lifespan Impairs Glucose Homeostasis and Insulin Sensitivity in Adult Mice
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    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EBAG9-deficient mice display decreased bone mineral density with suppressed autophagy
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  65. Jan 2024
  66. www.sciencedirect.com www.sciencedirect.com
    IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids
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    Decreased nitrosylation of CaMKII causes aging-associated impairments in memory and synaptic plasticity in mice
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    Identification of activity-based biomarkers for early-stage pancreatic tumors in blood using single-molecule enzyme activity screening
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    Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma
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  73. Dec 2023
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis
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    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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    A protocol to investigate the effects of lncRNAs on in vivo protein-protein interactions using proximity ligation assay
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    TOR inactivation triggers heterochromatin formation in rDNA during glucose starvation
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    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
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    Streptozotocin-Induced Diabetic Rats Showed a Differential Glycine Receptor Expression in the Spinal Cord: A GlyR Role in Diabetic Neuropathy
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    Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines
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  81. Nov 2023
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    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    Deep mutational scanning highlights a role for cytosolic regions in Hrd1 function
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    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
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    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
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    Antitumor effects of PRMT5 inhibition in sarcomas
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  89. Oct 2023
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    PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly
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    Regulation of STING activity in DNA sensing by ISG15 modification
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    WIP1 is a novel specific target for growth hormone action
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  93. 52.53.155.43 52.53.155.43
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  94. www.nature.com www.nature.com
    SIRT1 is an actionable target to restore p53 function in HPV-associated cancer therapy
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    TERRA R-loops connect and protect sister telomeres in mitosis
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    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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  97. www.cell.com www.cell.com
    Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain
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    Glutamate transporter contribution to retinal ganglion cell vulnerability in a rat model of multiple sclerosis
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    The fruit fly acetyltransferase chameau promotes starvation resilience at the expense of longevity
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    Decreased nitrosylation of CaMKII causes aging-associated impairments in memory and synaptic plasticity in mice
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    Systematic profiling of dominant ubiquitin variants reveals key functional nodes contributing to evolutionary selection
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    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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    Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage
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    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
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    Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome
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    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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  109. www.cell.com www.cell.com
    Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene
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    Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization
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  111. Jun 2023
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    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
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    Breast cancer cell mesenchymal transition and metastasis directed by DAP5/eIF3d-mediated selective mRNA translation
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    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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    KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway
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  116. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Homeostatic Regulation of Seizure Susceptibility and Cognitive Function by ER Quality Controller Derlin-1 through Maintenance of Adult Neurogenesis
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  118. May 2023
  119. www.sciencedirect.com www.sciencedirect.com
    Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells
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    An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
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    Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases
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    Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V
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    Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
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  124. Apr 2023
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    Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases
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    Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling
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  127. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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    Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V
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    N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
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  130. Mar 2023
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    Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
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  132. 52.53.155.43 52.53.155.43
    Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes
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  133. journals.physiology.org journals.physiology.org
    Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes
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    Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells
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    Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
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  136. www.tandfonline.com www.tandfonline.com
    Identification of an immunodominant region on a group A Streptococcus T-antigen reveals temperature-dependent motion in pili
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      DOI: 10.1080/21505594.2023.2180228

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  137. Feb 2023
  138. www.sciencedirect.com www.sciencedirect.com
    Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
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  140. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control
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    Development of a bispecific DNA-aptamer-based lysosome-targeting chimera for HER2 protein degradation
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An inactivated SARS-CoV-2 vaccine induced cross-neutralising persisting antibodies and protected upon challenge in small animals
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  143. www.mdpi.com www.mdpi.com
    Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53null Colorectal Cancer Cell Line
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  144. www.sciencedirect.com www.sciencedirect.com
    Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease
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  145. Jan 2023
  146. www.sciencedirect.com www.sciencedirect.com
    Seasonal cues act through the circadian clock and pigment-dispersing factor to control EYES ABSENT and downstream physiological changes
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    Protocol for the analysis of double-stranded RNAs in virus-infected insect cells using anti-dsRNA antibodies
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative tissue proteomics reveals unique action mechanisms of vaccine adjuvants
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  150. www.sciencedirect.com www.sciencedirect.com
    Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
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    Functional partitioning of transcriptional regulators by patterned charge blocks
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  152. Dec 2022
  153. www.sciencedirect.com www.sciencedirect.com
    AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling a single-stranded DNA region within an rDNA segment that affects the loading of bacterial condensin
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Survivin promotes a glycolytic switch in CD4+ T cells by suppressing the transcription of PFKFB3 in rheumatoid arthritis
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  156. Nov 2022
  157. www.cell.com www.cell.com
    Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity
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    cell.com/cell-reports/abstract/S2211-1247(22)01347-X
  158. www.sciencedirect.com www.sciencedirect.com
    ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation
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    The target antigen determines the mechanism of acquired resistance to T cell-based therapies
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  160. Oct 2022
  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1
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  162. www.sciencedirect.com www.sciencedirect.com
    Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Global Protein-RNA Interaction map of ESRP1 defines a post-transcriptional program that is essential for epithelial cell function
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BK Polyomavirus Requires the Mismatch Repair Pathway for DNA Damage Response Activation
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  165. www.sciencedirect.com www.sciencedirect.com
    KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice
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  166. Sep 2022
  167. www.sciencedirect.com www.sciencedirect.com
    ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor
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  169. www.sciencedirect.com www.sciencedirect.com
    Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover
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    In vivo characterization of Drosophila golgins reveals redundancy and plasticity of vesicle capture at the Golgi apparatus
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    Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation
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    A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer
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      DOI: 10.1016/j.crmeth.2022.100289

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  173. www.nature.com www.nature.com
    A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice
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      DOI: 10.1038/s42003-022-03917-5

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  174. www.sciencedirect.com www.sciencedirect.com
    Sublethal cytochrome c release generates drug-tolerant persister cells
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  175. Aug 2022
  176. www.sciencedirect.com www.sciencedirect.com
    CRISPR engineered mouse embryonic stem cells with Sox2-tdTomato and Gata6-GFP knock-in for endoderm differentiation
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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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  178. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 Delta spike protein enhances the viral fusogenicity and inflammatory cytokine production
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  179. Jul 2022
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS
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    Mapping of STB/HAP1 immunoreactivity in the mouse brainstem and its relationships with choline acetyltransferase, with special emphasis on cranial nerve motor and preganglionic autonomic nuclei
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    Guiding ATR and PARP inhibitor combinationswith chemogenomic screens
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  183. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oral Cancer Cells Release Vesicles that Cause Pain
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex
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  185. link.springer.com link.springer.com
    Phloretin inhibits glucose transport and reduces inflammation in human retinal pigment epithelial cells
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      DOI: 10.1007/s11010-022-04504-2

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  186. Jun 2022
  187. www.sciencedirect.com www.sciencedirect.com
    Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo
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      DOI: 10.1016/j.crmeth.2022.100235

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    Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses
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    Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
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    CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development
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  191. elifesciences.org elifesciences.org
    METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
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    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
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    Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones
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    Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine
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    Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
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  196. May 2022
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    Aβ-induced synaptic impairments require CaMKII activity that is stimulated by indirect signaling events
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    Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes
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    The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes
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    Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15
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    Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the Skeletal Myogenic Lineage in Human Pluripotent Stem Cell-Derived Teratomas
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  203. aacrjournals.org aacrjournals.org
    Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma
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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes
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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors
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  206. Apr 2022
  207. www.sciencedirect.com www.sciencedirect.com
    The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets
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    Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs
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    Yeast cell death pathway requiring AP-3 vesicle trafficking leads to vacuole/lysosome membrane permeabilization
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    Carbamazepine promotes surface expression of mutant Kir6.2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy
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  211. Mar 2022
  212. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis
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    Self-incompatibility requires GPI anchor remodeling by the poppy PGAP1 ortholog HLD1
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    The mTOR chromatin-bound interactome in prostate cancer
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    MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes
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    The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity
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    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice
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    Deficiency of Mesencephalic Astrocyte-derived Neurotrophic Factor Affects Neurogenesis in Mouse Brain
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  220. Feb 2022
  221. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    The anti-aging protein Klotho affects early postnatal myogenesis by downregulating Jmjd3 and the canonical Wnt pathway
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    Ligand-mediated PAI-1 inhibition in a mouse model of peritoneal carcinomatosis
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    Mechanistic impact of oligomer poisoning by dominant-negative CARD11 variants
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    ROPGAP-dependent interaction between brassinosteroid and ROP2-GTPase signaling controls pavement cell shape in Arabidopsis
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