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  2. www.sciencedirect.com www.sciencedirect.com
    Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans-fat-induced atherosclerosis
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    1. scibot 21 Nov 2024
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    sciencedirect.com/science/article/pii/S1550413124004121
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    Profound synthetic lethality between SMARCAL1 and FANCM
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    ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization
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    pmc.ncbi.nlm.nih.gov/articles/PMC11559990/
  5. Nov 2024
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    Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis
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    1. scibot 14 Nov 2024
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    Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation
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    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma
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    DYRK1A interacts with the tuberous sclerosis complex and promotes mTORC1 activity
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    Comparative Analysis of Host Cell Entry Efficiency and Neutralization Sensitivity of Emerging SARS-CoV-2 Lineages KP.2, KP.2.3, KP.3, and LB.1
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  11. Oct 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer
    1
    1. scibot 09 Oct 2024
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    sciencedirect.com/science/article/pii/S0092867424010729
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    Metabolic mapping of the human solute carrier superfamily
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    1. scibot 03 Oct 2024
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    biorxiv.org/content/10.1101/2024.09.23.614124v1
  14. Sep 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction
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    1. scibot 29 Sep 2024
      52961

      DOI: 10.1126/sciadv.adl5638

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    ncbi.nlm.nih.gov/pmc/articles/PMC466957/
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    R-loop resolution by ARIP4 helicase promotes androgen-mediated transcription induction
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    Targeting conserved TIM3+VISTA+ tumor-associated macrophages overcomes resistance to cancer immunotherapy
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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription
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    BL-918 activates PINK1/Parkin signaling pathway to ameliorate the progression of Parkinson’s disease
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      52961

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    E-cadherin loss drives diffuse-type gastric tumorigenesis via EZH2-mediated reprogramming
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      52961

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    TRMT10A dysfunction perturbs codon translation of initiator methionine and glutamine and impairs brain functions in mice
    1
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      52961

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    academic.oup.com/nar/article/52/15/9230/7697529
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    P53-dependent hypusination of eIF5A affects mitochondrial translation and senescence immune surveillance
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    Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization
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    Novel insights into vancomycin-loaded calcium sulfate and negative pressure wound therapy in preventing infections in open fractures
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      52,961

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    Chemical genetic screens reveal defective lysosomal trafficking as synthetic lethal with NF1 loss
    1
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    The Role of TIM-1 and CD300a in Zika Virus Infection Investigated with Cell-Based Electrical Impedance
    1
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      52961

      DOI: 10.3390/bios14080362

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    Phosphorylation of GCN2 by mTOR confers adaptation to conditions of hyper-mTOR activation under stress
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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrin α2 is an early marker for osteoclast differentiation that contributes to key steps in osteoclastogenesis
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      52961

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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer
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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis
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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LINC00894 Regulates Cerebral Ischemia/Reperfusion Injury by Stabilizing EIF5 and Facilitating ATF4-Mediated Induction of FGF21 and ACOD1 Expression
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      52,961

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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2
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      52961

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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Fluorinated NAD Precursors Enhance FK866 Cytotoxicity by Activating SARM1 in Glioblastoma Cells
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      DOI: 10.3390/biology13090649

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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HRS Facilitates Newcastle Disease Virus Replication in Tumor Cells by Promoting Viral Budding
    1
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      DOI: 10.3390/ijms251810060

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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dihydrotestosterone Enhances MICA-Mediated Immune Responses to Epstein–Barr Virus-Associated Gastric Carcinoma
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      DOI: 10.3390/cancers16183219

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SPRED3 regulates the NF-κB signaling pathway in thyroid cancer and promotes the proliferation
    1
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      lentiCRISPRv2

      DOI: 10.1038/s41598-024-61075-6

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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT
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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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    The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation
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      plasmid_52961

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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis
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  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP26 as a hepatitis B virus-induced deubiquitinase primes hepatocellular carcinogenesis by epigenetic remodeling
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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-glycosylation by Mgat5 imposes a targetable constraint on immune-mediated tumor clearance
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    4EBP1-mediated SLC7A11 protein synthesis restrains ferroptosis triggered by MEK inhibitors in advanced ovarian cancer
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      lentiCRISPR v2

      DOI: 10.1172/jci.insight.177857

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclophilin J limits linear ubiquitin signaling and controls colorectal cancer progression
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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment
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    Mitochondrial RNA cytosolic leakage drives the SASP
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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KAT6A Condensates Impair PARP1 Trapping of PARP Inhibitors in Ovarian Cancer
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  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glaesserella parasuis serotype 4 exploits fibronectin via RlpA for tracheal colonization following porcine circovirus type 2 infection
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor suppressor BAP1 suppresses disulfidptosis through the regulation of SLC7A11 and NADPH levels
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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DPM1 modulates desmosomal adhesion and epidermal differentiation through SERPINB5
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A heterocyclic compound inhibits viral release by inducing cell surface BST2/Tetherin/CD317/HM1.24
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPases*
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      (https://media.addgene.or

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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of immortal-like and functional CAR T cells by defined factors
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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC8 Enhances the Function of HIF‐2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC
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      52 961

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  56. www.sciencedirect.com www.sciencedirect.com
    Saturation mutagenesis-reinforced functional assays for disease-related genes
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  57. www.biorxiv.org www.biorxiv.org
    PEBP1 amplifies mitochondrial dysfunction induced integrated stress response
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  58. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Retinoic acid-induced protein 14 links mechanical forces to Hippo signaling
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A suite of genome-engineered hepatic cells provides novel insights into the spatiotemporal metabolism of apolipoprotein B and apolipoprotein B–containing lipoprotein secretion
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human tetraspanin CD81 facilitates invasion of Salmonella enterica into human epithelial cells
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STIM1 promotes acquired resistance to sorafenib by attenuating ferroptosis in hepatocellular carcinoma
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      lentiCRISPR v2

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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockout of the WD40 domain of ATG16L1 enhances foot and mouth disease virus replication
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      lentiCRISPRv2

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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts
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      Lenti-CRISPR v2

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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circumventing resistance within the Ewing sarcoma microenvironment by combinatorial innate immunotherapy
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recruitment of the m6A/m6Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48
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      plasmid_52961

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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the AGR2-NPM3 axis uncovers the AGR2 involvement in PD-L1 regulation in colorectal cancer
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 ORF10 hijacking ubiquitination machinery reveals potential unique drug targeting sites
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASCT2 is a major contributor to serine uptake in cancer cells
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA helicase SKIV2L limits antiviral defense and autoinflammation elicited by the OAS-RNase L pathway
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  73. www.sciencedirect.com www.sciencedirect.com
    A Platform to Deliver Single and Bi-specific Cas9/guide RNA to Perturb Genes in Vitro and in Vivo
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  74. www.sciencedirect.com www.sciencedirect.com
    Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Contribution of A1 to macrophage survival in cooperation with MCL-1 and BCL-XL in a murine cell model of myeloid differentiation
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      plasmid_52961

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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential utilization of vitamin B12-dependent and independent pathways for propionate metabolism across human cells
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    A TBK1-independent primordial function of STING in lysosomal biogenesis
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screening identifies tyrosylprotein sulfotransferase-2 as a target for augmenting anti-PD1 efficacy
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      plasmid_52

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The expression of PD-L1 on tumor-derived exosomes enhances infiltration and anti-tumor activity of αCD3 × αPD-L1 bispecific antibody-armed T cells
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      plasmid_52

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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enzalutamide Sensitizes Castration‐Resistant Prostate Cancer to Copper‐Mediated Cell Death
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas and CRISPR-based screening system for precise gene editing and targeted cancer therapy
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      Addgene_52

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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elongin B promotes breast cancer progression by ubiquitinating tumor suppressor p14/ARF
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dampened Regulatory Circuitry of TEAD1/ITGA1/ITGA2 Promotes TGFβ1 Signaling to Orchestrate Prostate Cancer Progression
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      plasmid_52

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  84. www.sciencedirect.com www.sciencedirect.com
    The GSK-3β-FBXL21 Axis Contributes to Circadian TCAP Degradation and Skeletal Muscle Function
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      RRID:Addgene_80089

      DOI: 10.1016/j.celrep.2020.108140

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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions
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  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FHL2 expression by cancer-associated fibroblasts promotes metastasis and angiogenesis in lung adenocarcinoma
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators
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    1. scibot 15 Sep 2024
      Addgene_52961

      DOI: 10.7554/eLife.99172

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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin-1 and UNC5B Cooperate with Integrins to Mediate YAP-Driven Cytostasis
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      RRID:Addgene_52961

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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic landscape profiling of primary prostate cancer reveals a 16-protein panel for prognosis prediction
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin
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  91. www.sciencedirect.com www.sciencedirect.com
    Pooled endogenous protein tagging and recruitment for systematic profiling of protein function
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes
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  93. www.sciencedirect.com www.sciencedirect.com
    Inhibitory co-receptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming
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  94. Aug 2024
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANGPTL4 suppresses clear cell renal cell carcinoma via inhibition of lysosomal acid lipase
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  97. www.sciencedirect.com www.sciencedirect.com
    Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
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    1. scibot 29 Aug 2024
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cellular turnover and degradation of the most common missense cystathionine beta‐synthase variants causing homocystinuria
    1
    1. scibot 26 Aug 2024
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UNC13B regulates the sensitivity of Wilms' tumor cells to doxorubicin by modulating lysosomes
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation efficiency covariation across cell types is a conserved organizing principle of mammalian transcriptomes
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    1. scibot 26 Aug 2024
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic combination of RAD51-SCR7 improves CRISPR-Cas9 genome editing efficiency by preventing R-loop accumulation
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    1. scibot 26 Aug 2024
      lentiCRISPRv2

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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disturbed glycolipid metabolism activates CXCL13-CXCR5 axis in senescent TSCs to promote heterotopic ossification
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      52,961

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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FYN-mediated phosphorylation of BCKDK at Y151 promotes GBM proliferation by increasing the oncogenic metabolite N-acetyl-L-alanine
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screening identifies critical role of phosphatase and tensin homologous (PTEN) in sensitivity of acute myeloid leukemia to chemotherapy
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    1. scibot 26 Aug 2024
      lentiCRISPRv2

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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Nr2e3 to Modulate Tet2 Expression: Therapeutic Potential for Depression Treatment
    1
    1. scibot 26 Aug 2024
      lenti‐CRISPR v2

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A plug-and-play monofunctional platform for targeted degradation of extracellular proteins and vesicles
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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PUS7‐dependent pseudouridylation of ALKBH3 mRNA inhibits gastric cancer progression
    1
    1. scibot 26 Aug 2024
      lentiCRISPR V2

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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 in acute myeloid leukemia facilitates natural killer cell-mediated surveillance
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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent inflammatory overactivation in acute myeloid leukemia (AML) cells
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging biotin-based proximity labeling to identify cellular factors governing early alphaherpesvirus infection
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The histamine receptor H1 acts as an alternative receptor for SARS-CoV-2 | mBio
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      plasmid_52961

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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TBK1 and IKKε protect target cells from IFNγ-mediated T cell killing via an inflammatory apoptotic mechanism
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a highly sensitive platform for protein–protein interaction detection and regulation of T cell function
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sub-genomic flaviviral RNA elements increase the stability and abundance of recombinant AAV vector transcripts
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipid synthesis, triggered by PPARγ T166 dephosphorylation, sustains reparative function of macrophages during tissue repair
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  117. www.sciencedirect.com www.sciencedirect.com
    A genetic basis for sex differences in Xp11 translocation renal cell carcinoma
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      Plasmid_52961

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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Valproic acid targets IDH1 mutants through alteration of lipid metabolism
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      RRID:Addgene_52961

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  119. www.sciencedirect.com www.sciencedirect.com
    Functional characterization of the SDR42E1 reveals its role in vitamin D biosynthesis
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A cellular reporter system to evaluate endogenous fetal hemoglobin induction and screen for therapeutic compounds
    1
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative genomics identifies SHPRH as a tumor suppressor gene in lung adenocarcinoma that regulates DNA damage response
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CA19-9-Positive Extracellular Vesicle Is a Risk Factor for Cancer-Associated Thrombosis in Pancreatic Cancer
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      Plasmid_52961

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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The actin binding protein profilin 1 localizes inside mitochondria and is critical for their function
    2
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      Addgene_52961

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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC4 influences the DNA damage response and counteracts senescence by assembling with HDAC1/HDAC2 to control H2BK120 acetylation and homology-directed repair
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  125. www.sciencedirect.com www.sciencedirect.com
    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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      RRID:Addgene_52961

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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The deubiquitinating enzyme USP35 regulates the stability of NRF2 protein
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      52961

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The caspase-activated DNase promotes cellular senescence
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    1. scibot 21 Aug 2024
      lentiCRISPR v2

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  128. www.sciencedirect.com www.sciencedirect.com
    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxysterole-binding protein targeted by SARS-CoV-2 viral proteins regulates coronavirus replication
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      DOI: 10.3389/fcimb.2024.1383917

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  130. www.biorxiv.org www.biorxiv.org
    Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer
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    1. scibot 20 Aug 2024
      LentiCRISPR.V2

      DOI: 10.1101/2024.07.10.602941

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  131. www.cell.com www.cell.com
    SYNGAP1 deficiency disrupts synaptic neoteny in xenotransplanted human cortical neurons in vivo
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  132. www.sciencedirect.com www.sciencedirect.com
    Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAST4 regulates stem cell maintenance with DLX3 for epithelial development and amelogenesis
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic transcriptome profiling of hPSC-derived osteoblasts unveils CORIN's mastery in governing osteogenesis through CEBPD modulation
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epitranscriptomic m5C methylation of SARS-CoV-2 RNA regulates viral replication and the virulence of progeny viruses in the new infection
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      lentiCRISPR-v2

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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Necroptosis‐Mediated Synergistic Photodynamic and Glutamine‐Metabolic Therapy Enabled by a Biomimetic Targeting Nanosystem for Cholangiocarcinoma
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      52 961

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  138. www.biorxiv.org www.biorxiv.org
    Transcriptional regulation of adipocyte lipolysis by IRF2BP2
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TXNRD1 drives innate immune response in senescent cells with implications in age-associated inflammation
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-L1 deglycosylation promotes its nuclear translocation and accelerates DNA double-strand-break repair in cancer
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metastatic breast cancer cells are metabolically reprogrammed to maintain redox homeostasis during metastasis
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LACTB suppresses liver cancer progression through regulation of ferroptosis
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  144. www.sciencedirect.com www.sciencedirect.com
    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A digital microfluidic device integrated with electrochemical sensor and 3D matrix for detecting soluble PD-L1
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arachidonic acid released by PIK3CA mutant tumor cells triggers malignant transformation of colonic epithelium by inducing chromatin remodeling
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD-mediated pyroptosis in colorectal cancer
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    2024.04.26.591029v1.full-html.html
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  152. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Frontiers | The Nonvesicular Sterol Transporter Aster-C Plays a Minor Role in Whole Body Cholesterol Balance
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      Lenti-CRISPER v2

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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tangible method to assess native ferroptosis suppressor activity
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress
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  156. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival
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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
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  158. www.pnas.org www.pnas.org
    Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia
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  159. journals.sagepub.com journals.sagepub.com
    Mismatch repair deficiency in canine neoplasms - Sakuya Inanaga, Masaya Igase, Yusuke Sakai, Mika Tanabe, Nozomi Shimonohara, Kazuhito Itamoto, Munekazu Nakaichi, Takuya Mizuno, 2021
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  160. www.embopress.org www.embopress.org
    A method for benchmarking genetic screens reveals a predominant mitochondrial bias
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  161. www.science.org www.science.org
    The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma
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  162. Jul 2024
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Artesunate induces melanoma cell ferroptosis and augments antitumor immunity through targeting Ido1
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
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  167. www.sciencedirect.com www.sciencedirect.com
    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
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  168. www.sciencedirect.com www.sciencedirect.com
    pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism
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  169. www.cell.com www.cell.com
    The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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  171. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
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      #52961, Addgene

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  172. www.science.org www.science.org
    HMMR triggers immune evasion of hepatocellular carcinoma by inactivation of phagocyte killing
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  173. rupress.org rupress.org
    PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway
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      DOI: 10.1084/jem.20221721

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  174. 52.53.155.43 52.53.155.43
    The_identification_of_CELSR3_and_other_p-html.html
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  175. www.tandfonline.com www.tandfonline.com
    Metabolic stress induces a double-positive feedback loop between AMPK and SQSTM1/p62 conferring dual activation of AMPK and NFE2L2/NRF2 to synergize antioxidant defense
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The COMPASS complex maintains the metastatic capacity imparted by a subpopulation of cells in UPS
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alpha-defensin binding expands human adenovirus tropism
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  179. www.sciencedirect.com www.sciencedirect.com
    Synthetic lethal CRISPR screen identifies a cancer cell-intrinsic role of PD-L1 in regulation of vulnerability to ferroptosis
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  180. www.cell.com www.cell.com
    SigmaR1 shapes rough endoplasmic reticulum membrane sheets
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  181. www.cell.com www.cell.com
    A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of Mettl3 in cholinergic neurons causes adult-onset neuromuscular degeneration
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The two-faced role of RNA methyltransferase METTL3 on cellular response to cisplatin in head and neck squamous cell carcinoma in vitro model
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Precise excision of HTLV-1 provirus with a designer-recombinase
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  185. www.sciencedirect.com www.sciencedirect.com
    Local vascular Klotho mediates diabetes-induced atherosclerosis via ERK1/2 and PI3-kinase-dependent signaling pathways.
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    γ-secretase facilitates retromer-mediated retrograde transport
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low BCL-xL expression in triple-negative breast cancer cells favors chemotherapy efficacy, and this effect is limited by cancer-associated fibroblasts
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  188. Jun 2024
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA-PK participates in pre-rRNA biogenesis independent of DNA double-strand break repair
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      LentiCRISPR v2 vector

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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vimentin-mediated buffering of internal integrin β1 pool increases survival of cells from anoikis
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D Chromatin Alteration by Disrupting β-Catenin/CBP Interaction Is Enriched with Insulin Signaling in Pancreatic Cancer
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET bromodomain inhibition potentiates radiosensitivity in models of H3K27-altered diffuse midline glioma
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    l-2-Hydroxyglutarate remodeling of the epigenome and epitranscriptome creates a metabolic vulnerability in kidney cancer models
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Somatic structural variants drive distinct modes of oncogenesis in melanoma
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  196. www.nature.com www.nature.com
    Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ufmylation cascade controls COPII recruitment, anterograde transport, and sorting of nascent GPCRs at ER
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolution of STAT2 resistance to flavivirus NS5 occurred multiple times despite genetic constraints
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tripartite Motif-Containing Protein 65 (TRIM65) Inhibits Hepatitis B Virus Transcription
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  200. www.cell.com www.cell.com
    An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-targeting JAK1/STAT6/GAS6/TAM signaling improves chemotherapy efficacy in Ewing sarcoma
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  203. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The homeobox transcription factor DUXBL controls exit from totipotency
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