349 Matching Annotations
  1. Last 7 days
  2. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma
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    1. scibot 27 Sep 2024
      RRID:CVCL_0004

      DOI: 10.1002/1878-0261.13735

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13735
  3. www.cell.com www.cell.com
    SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
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    1. scibot 26 Sep 2024
      RRID:CVCL_0004

      DOI: 10.1016/j.celrep.2024.114536

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    cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SJPedPanel: A pan-cancer gene panel for childhood malignancies to enhance cancer monitoring and early detection
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    1. scibot 25 Sep 2024
      CVCL_0004

      DOI: 10.1158/1078-0432.CCR-24-1063

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    ncbi.nlm.nih.gov/pmc/articles/PMC11393547/
  5. Sep 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic effects of PARP inhibition and cholesterol biosynthesis pathway modulation
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    1. scibot 18 Sep 2024
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      DOI: 10.1158/2767-9764.CRC-23-0549

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    ncbi.nlm.nih.gov/pmc/articles/PMC11403291/
  7. www.sciencedirect.com www.sciencedirect.com
    Validation of a PD-1/CD28 chimeric switch receptor to augment CAR-T function in dogs with spontaneous B cell lymphoma
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    1. scibot 17 Sep 2024
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    sciencedirect.com/science/article/pii/S2589004224020881
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nanodynamo quantifies subcellular RNA dynamics revealing extensive coupling between steps of the RNA life cycle
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      DOI: 10.1038/s41467-024-51917-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11375098/
  9. Aug 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    1. scibot 18 Aug 2024
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      DOI: 10.1158/0008-5472.CAN-23-3031

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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  11. www.sciencedirect.com www.sciencedirect.com
    Generation of densely labeled oligonucleotides for the detection of small genomic elements
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    1. scibot 14 Aug 2024
      CCL-243

      DOI: 10.1016/j.crmeth.2024.100840

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    sciencedirect.com/science/article/pii/S2667237524002133
  12. www.biorxiv.org www.biorxiv.org
    Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states
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    1. scibot 13 Aug 2024
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    biorxiv.org/content/10.1101/2024.07.31.606073v1
  13. www.cell.com www.cell.com
    The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
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    1. scibot 13 Aug 2024
      CCL-243

      DOI: 10.1016/j.molcel.2024.06.031

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    cell.com/molecular-cell/fulltext/S1097-2765(24)00538-0
  14. www.cell.com www.cell.com
    Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle
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    cell.com/molecular-cell/fulltext/S1097-2765(24)00511-2
  15. www.mdpi.com www.mdpi.com
    Soluble Expression of Fc-Fused T Cell Receptors Allows Yielding Novel Bispecific T Cell Engagers
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    1. scibot 02 Aug 2024
      RRID: CVCL_0004

      DOI: 10.3390/biomedicines9070790

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    mdpi.com/2227-9059/9/7/790/htm
  16. Jul 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BTK acts as a modulator of the response to imatinib in chronic myeloid leukemia
    1
    1. scibot 20 Jul 2024
      RRID:CVCL_0004

      DOI: 10.3892/ol.2024.14557

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    ncbi.nlm.nih.gov/pmc/articles/PMC11253089/
  18. www.sciencedirect.com www.sciencedirect.com
    Interface-guided phenotyping of coding variants in the transcription factor RUNX1
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    1. scibot 18 Jul 2024
      RRID:CVCL_0004

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    sciencedirect.com/science/article/pii/S2211124724007654
  19. www.nature.com www.nature.com
    Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
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    1. scibot 18 Jul 2024
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      DOI: 10.1038/s41375-024-02328-1

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    nature.com/articles/s41375-024-02328-1
  20. www.sciencedirect.com www.sciencedirect.com
    Base-resolution m5C profiling across the mammalian transcriptome by bisulfite-free enzyme-assisted chemical labeling approach
    1
    1. scibot 17 Jul 2024
      CCL-243

      DOI: 10.1016/j.molcel.2024.06.021

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  21. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Jul 2024
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      DOI: 10.1111/bph.16489

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  22. www.mdpi.com www.mdpi.com
    Enhanced Antitumor Activity by the Combination of Dasatinib and Selinexor in Chronic Myeloid Leukemia
    1
    1. scibot 12 Jul 2024
      CCL-243

      DOI: 10.3390/ph17070894

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    mdpi.com/1424-8247/17/7/894
  23. www.cell.com www.cell.com
    Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
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      DOI: 10.1016/j.stem.2024.06.011

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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00219-4
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets
    1
    1. scibot 04 Jul 2024
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      DOI: 10.1136/jitc-2024-009410

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    ncbi.nlm.nih.gov/pmc/articles/PMC11218003/
  25. Jun 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
    1
    1. scibot 30 Jun 2024
      RRID:CVCL_0004

      DOI: 10.1016/j.isci.2024.110120

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    ncbi.nlm.nih.gov/pmc/articles/PMC11209011/
  27. link.springer.com link.springer.com
    β-Carboline derivatives are potent against Acute Myeloid Leukemia in vitro and in vivo
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    1. scibot 28 Jun 2024
      RRID:CVCL_0004

      DOI: 10.1007/s43440-024-00614-4

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    link.springer.com/article/10.1007/s43440-024-00614-4
  28. www.sciencedirect.com www.sciencedirect.com
    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
    1
    1. scibot 06 Jun 2024
      CCL-243

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    sciencedirect.com/science/article/pii/S2666379124002842
  29. www.sciencedirect.com www.sciencedirect.com
    Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
    1
    1. scibot 04 Jun 2024
      CCL-243

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    sciencedirect.com/science/article/pii/S1534580724003277
  30. May 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    sciencedirect.com/science/article/pii/S1535610824001697
  32. link.springer.com link.springer.com
    Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer’s disease
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    link.springer.com/article/10.1186/s13024-024-00725-9
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LncRNA IRAIN overcomes imatinib resistance in chronic myeloid leukemia via NF-κB/CD44 pathway inhibition
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      DOI: 10.1016/j.isci.2024.109851

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      RRID:CVCL_0004

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    ncbi.nlm.nih.gov/pmc/articles/PMC11112338/
  34. www.sciencedirect.com www.sciencedirect.com
    Targeting MCL1-driven anti-apoptotic pathways overcomes blast progression after hypomethylating agent failure in chronic myelomonocytic leukemia
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    1. scibot 23 May 2024
      CCL243

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    sciencedirect.com/science/article/pii/S2666379124002775
  35. www.sciencedirect.com www.sciencedirect.com
    CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
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      CCL-243

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    sciencedirect.com/science/article/pii/S2666379124002647
  36. www.biorxiv.org www.biorxiv.org
    Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations
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      DOI: 10.1101/2024.01.26.576051

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    biorxiv.org/content/10.1101/2024.01.26.576051v1
  37. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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      DOI: 10.7554/eLife.90683

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    elifesciences.org/articles/90683
  38. link.springer.com link.springer.com
    Therapeutic potential of third-generation chimeric antigen receptor T cells targeting B cell maturation antigen for treating multiple myeloma
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      DOI: 10.1007/s10238-024-01347-7

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    link.springer.com/article/10.1007/s10238-024-01347-7
  39. Apr 2024
  40. www.sciencedirect.com www.sciencedirect.com
    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
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      CCL-243

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    sciencedirect.com/science/article/pii/S1097276524002843
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule
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    ncbi.nlm.nih.gov/pmc/articles/PMC11039342/
  42. www.sciencedirect.com www.sciencedirect.com
    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
    1
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      JCRB0019

      DOI: 10.1016/j.xcrm.2024.101526

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    sciencedirect.com/science/article/pii/S2666379124001952
  43. www.sciencedirect.com www.sciencedirect.com
    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
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      CCL-243

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    sciencedirect.com/science/article/pii/S2211124724004728
  44. www.sciencedirect.com www.sciencedirect.com
    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
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    1. scibot 24 Apr 2024
      Cat# CCL-243

      DOI: 10.1016/j.cell.2024.03.039

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    sciencedirect.com/science/article/pii/S0092867424003556
  45. www.sciencedirect.com www.sciencedirect.com
    Protocol for isolation of tumor-derived extracellular vesicles and functional studies on human T cell subsets
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      CCL-243

      DOI: 10.1016/j.xpro.2024.103011

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    sciencedirect.com/science/article/pii/S266616672400176X
  46. www.sciencedirect.com www.sciencedirect.com
    A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response
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      Cat#CCL-243, RRID: CVCL_0004

      DOI: 10.1016/j.xcrm.2024.101511

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    sciencedirect.com/science/article/pii/S2666379124001800
  47. www.sciencedirect.com www.sciencedirect.com
    Chromatin context-dependent regulation and epigenetic manipulation of prime editing
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      CCL-243

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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma
    1
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      RRID:CVCL_0004

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  49. Mar 2024
  50. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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      CCL-243

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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
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  52. www.sciencedirect.com www.sciencedirect.com
    EPC1/2 regulate hematopoietic stem and progenitor cell proliferation by modulating H3 acetylation and DLST
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced representative methylome profiling of cell-free DNA for breast cancer detection
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  54. Feb 2024
  55. 52.53.155.43 52.53.155.43
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-Vα24Jα18 TCR antibody tunes iNKT cell responses to target and kill CD1d-negative tumors in an FcγRII (CD32)-dependent manner
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  57. www.sciencedirect.com www.sciencedirect.com
    SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells
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      ATCC# CCL-243

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  58. www.sciencedirect.com www.sciencedirect.com
    ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion
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      ATCCCat #CCL-243

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  59. www.sciencedirect.com www.sciencedirect.com
    Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editing
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      ATCCCat# CCL-243

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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune evasion by proteolytic shedding of natural killer group 2, member D ligands in Helicobacter pylori infection
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  61. www.sciencedirect.com www.sciencedirect.com
    Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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  63. Jan 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Short tandem repeat profiling via next-generation sequencing for cell line authentication
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      CVCL_0004

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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-15-dependent immune crosstalk between natural killer cells and dendritic cells in HIV-1 elite controllers
    1
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      CVCL_004

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  66. link.springer.com link.springer.com
    Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet
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  67. Dec 2023
  68. www.sciencedirect.com www.sciencedirect.com
    Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma
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  69. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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  70. www.sciencedirect.com www.sciencedirect.com
    iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
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      JCRB0019

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  71. Nov 2023
  72. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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  73. www.nature.com www.nature.com
    Scalable single-cell profiling of chromatin modifications with sciCUT&Tag
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  74. link.springer.com link.springer.com
    Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screen for genome‐wide interrogation of essential MYC‐bound E‐boxes in cancer cells
    1
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  76. www.sciencedirect.com www.sciencedirect.com
    Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells
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  77. Oct 2023
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unedited allogeneic iNKT cells show extended persistence in MHC-mismatched canine recipients
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  79. www.nature.com www.nature.com
    A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
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  80. www.sciencedirect.com www.sciencedirect.com
    Enhanced antitumor efficacy, proliferative capacity, and alleviation of T cell exhaustion by fifth-generation chimeric antigen receptor T cells targeting B cell maturation antigen in multiple myeloma
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Identification of neoepitope reactive T-cell receptors guided by HLA-A*03:01 and HLA-A*11:01 immunopeptidomics
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      DOI: 10.1136/jitc-2023-007097

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  82. Sep 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
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      RRID:CVCL_0004

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  84. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Yin-html.html
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  85. Aug 2023
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eradication of CD48 positive tumors by selectively enhanced YTS cells harnessing the lncRNA NeST
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  87. www.biorxiv.org www.biorxiv.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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      DOI: 10.1101/2023.07.26.550648

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    biorxiv.org/content/10.1101/2023.07.26.550648v2
  88. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Expression of circular RNAs in myelodysplastic neoplasms and their association with mutations in the splicing factor gene SF3B1
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  89. Jul 2023
  90. link.springer.com link.springer.com
    Good manufacturing practice production of CD34+ progenitor-derived NK cells for adoptive immunotherapy in acute myeloid leukemia
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      RRID:CVCL_0004

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  91. 52.53.155.43 52.53.155.43
    Conditional lethality profiling reveals anticancer mechanisms of action and drug-nutrient interactions
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      RRID:_CVCL_0004

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  92. Jun 2023
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models
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      DOI: 10.3389/fonc.2023.1200897

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  94. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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  95. link.springer.com link.springer.com
    The antitumor effects of WNT5A against hematological malignancies
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      RRID:CVCL_0004

      DOI: 10.1007/s12079-023-00773-8

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  96. aacrjournals.org aacrjournals.org
    EBV-upregulated B7-H3 inhibits NK cell-mediated antitumor function and contributes to nasopharyngeal carcinoma progression
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      DOI: 10.1158/2326-6066.CIR-22-0374

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  97. www.sciencedirect.com www.sciencedirect.com
    Minor intron splicing is critical for survival of lethal prostate cancer
    1
    1. scibot 09 Jun 2023
      RRID: CCL-243

      DOI: 10.1016/j.molcel.2023.05.017

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  98. www.sciencedirect.com www.sciencedirect.com
    Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia
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    1. scibot 09 Jun 2023
      RRID:CVCL_0004

      DOI: 10.1016/j.ccell.2023.05.002

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  99. www.science.org www.science.org
    Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis
    1
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      RRID:CVCL_0004

      DOI: 10.1126/sciimmunol.adg3196

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  100. link.springer.com link.springer.com
    Tumor cell-intrinsic and tumor microenvironmental conditions co-determine signaling by the glycoimmune checkpoint receptor Siglec-7
    1
    1. scibot 01 Jun 2023
      RRID:CVCL_0004

      DOI: 10.1007/s00018-023-04816-6

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    link.springer.com/article/10.1007/s00018-023-04816-6
  101. May 2023
  102. link.springer.com link.springer.com
    Potential role of the P2X7 receptor in the proliferation of human diffused large B-cell lymphoma
    1
    1. scibot 25 May 2023
      RRID:CVCL_0004

      DOI: 10.1007/s11302-023-09947-w

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  103. link.springer.com link.springer.com
    Discovery of two new isoforms of the human DUT gene
    1
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      CVCL_0004

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  104. www.biorxiv.org www.biorxiv.org
    Killing the enemy or making it your ally? The effects of thiostrepton on tumor associated macrophages
    1
    1. scibot 09 May 2023
      CCL-243

      DOI: 10.1101/2023.03.23.533899

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    biorxiv.org/content/10.1101/2023.03.23.533899v1
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reverse translation identifies the synergistic role of immune checkpoint blockade and IL-15 to enhance immunotherapy of ovarian cancer
    1
    1. scibot 06 May 2023
      RRID:CVCL_0004

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  106. Apr 2023
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types
    1
    1. scibot 12 Apr 2023
      ATCC, CCL-243

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    ncbi.nlm.nih.gov/pmc/articles/PMC10028905/
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-suppressor scanning for systematic discovery of drug resistance mutations
    1
    1. scibot 12 Apr 2023
      RRID:CVCL_0004

      DOI: 10.1002/cpz1.614

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  109. link.springer.com link.springer.com
    Development of an antibody-ligand fusion protein scFvCD16A-sc4-1BBL in Komagataella phaffii with stimulatory activity for Natural Killer cells
    1
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      RRID:CVCL_0004

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  110. Mar 2023
  111. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 29 Mar 2023
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      DOI: 10.1002/1878-0261.13422

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13422
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tri-specific killer engager against mesothelin targets NK cells towards lung cancer
    1
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      CVCL_0004

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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced Costimulatory Signaling Improves CAR T-cell Effector Responses in CLL
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      DOI: 10.1158/2767-9764.CRC-22-0200

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  114. www.sciencedirect.com www.sciencedirect.com
    Oxygen toxicity causes cyclic damage by destabilizing specific Fe-S cluster-containing protein complexes
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery
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      RRID:CVCL_0004

      DOI: 10.7554/eLife.80640

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  116. Feb 2023
  117. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD
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      RRID:CVCL_0004

      DOI: 10.1002/1878-0261.13368

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  118. www.nature.com www.nature.com
    Quantitative multiple fragment monitoring with enhanced in-source fragmentation/annotation mass spectrometry
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  119. Jan 2023
  120. www.nature.com www.nature.com
    Chem-map profiles drug binding to chromatin in cells
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    1. scibot 27 Jan 2023
      RRID:CVCL_0004

      DOI: 10.1038/s41587-022-01636-0

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  121. www.sciencedirect.com www.sciencedirect.com
    Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma
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      CCL-243

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    sciencedirect.com/science/article/pii/S1534580722008942
  122. www.science.org www.science.org
    Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis
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      RRID:CVCL_0004

      DOI: 10.1126/scisignal.abh1083

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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of CAR-T cells specifically targeting cancer stem cell antigen DNAJB8 against solid tumours
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      RRID:CVCL_0004

      DOI: 10.1038/s41416-022-02100-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977765/
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain
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      DOI: 10.1158/1535-7163.MCT-21-0552

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    ncbi.nlm.nih.gov/pmc/articles/PMC9377753/
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modified manufacturing process modulates CD19CAR T-cell engraftment fitness and leukemia-free survival in pediatric and young adult subjects
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    ncbi.nlm.nih.gov/pmc/articles/PMC9250626/
  126. www.sciencedirect.com www.sciencedirect.com
    Indoxyl sulfate impairs erythropoiesis at BFU-E stage in chronic kidney disease
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  127. Dec 2022
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genetically engineered, stem-cell-derived cellular vaccine
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      CCL-243

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  129. www.mdpi.com www.mdpi.com
    The Microalga Skeletonema marinoi Induces Apoptosis and DNA Damage in K562 Cell Line by Modulating NADPH Oxidase
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      RRID:CVCL_0004

      DOI: 10.3390/molecules27238270

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    mdpi.com/1420-3049/27/23/8270
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-throughput proteomics of nanogram-scale samples with Zeno SWATH MS
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      DOI: 10.7554/eLife.83947

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  131. Nov 2022
  132. www.sciencedirect.com www.sciencedirect.com
    Profiling lariat intermediates reveals genetic determinants of early and late co-transcriptional splicing
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      CCL-243

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  133. www.nature.com www.nature.com
    A nascent peptide code for translational control of mRNA stability in human cells
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  134. Oct 2022
  135. www.sciencedirect.com www.sciencedirect.com
    Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
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      10243

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  136. www.sciencedirect.com www.sciencedirect.com
    GPC3-Unc5 receptor complex structure and role in cell migration
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      RRID:CVCL_0004

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    sciencedirect.com/science/article/pii/S0092867422011977
  137. www.sciencedirect.com www.sciencedirect.com
    MCL-1 is a master regulator of cancer dependency on fatty acid oxidation
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      Cat #CCL-243

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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient and reversible Cas13d-mediated knockdown with an all-in-one lentivirus-vector
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  139. Sep 2022
  140. www.sciencedirect.com www.sciencedirect.com
    CDK12 regulates co-transcriptional splicing and RNA turnover in human cells
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  141. www.sciencedirect.com www.sciencedirect.com
    Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CANCER-ASSOCIATED SF3B1 MUTATIONS CONFER A BRCA-LIKE CELLULAR PHENOTYPE AND SYNTHETIC LETHALITY TO PARP INHIBITORS
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  143. Aug 2022
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells
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      DOI: 10.1172/JCI153514

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  145. www.sciencedirect.com www.sciencedirect.com
    Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species
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      ATCCCCL-243

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    sciencedirect.com/science/article/pii/S1931312822003596
  146. www.sciencedirect.com www.sciencedirect.com
    The BASP1 transcriptional corepressor modifies chromatin through lipid-dependent and lipid-independent mechanisms
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      RRID:CVCL_0004

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    sciencedirect.com/science/article/pii/S2589004222010689
  147. www.sciencedirect.com www.sciencedirect.com
    Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes
    1
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    sciencedirect.com/science/article/pii/S1535610822003191
  148. Jul 2022
  149. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Randomized multicenter phase II trial of prophylactic irradiation of para-aortic lymph nodes in advanced cervical cancer according to tumor hypoxia: Korean Radiation Oncology Group (KROG 07-01) study
    1
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      RRID:CVCL_0004

      DOI: 10.1002/ijc.34190

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  150. www.sciencedirect.com www.sciencedirect.com
    Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5
    1
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      ATCCCCL-243

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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide expression and methylation analyses reveal aberrant cell adhesion signaling in tyrosine kinase inhibitor-resistant CML cells
    1
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      RRID:CVCL_0004

      DOI: 10.3892/or.2022.8355

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  152. Jun 2022
  153. 52.53.155.43 52.53.155.43
    cir-21-0501-html.html
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  154. www.sciencedirect.com www.sciencedirect.com
    A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Simple and Robust Single-Step Method for CAR-Vδ1 γδT Cell Expansion and Transduction for Cancer Immunotherapy
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  156. www.sciencedirect.com www.sciencedirect.com
    Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes
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      ATCCCCL-243

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  157. May 2022
  158. aacrjournals.org aacrjournals.org
    Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors
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  159. www.sciencedirect.com www.sciencedirect.com
    Trafficking and persistence of alloantigen-specific chimeric antigen receptor regulatory T cells in Cynomolgus macaque
    1
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      ATCCCCL-243

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  160. www.tandfonline.com www.tandfonline.com
    JMJD1C-regulated lipid synthesis contributes to the maintenance of MLL-rearranged acute myeloid leukemia
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  161. www.tandfonline.com www.tandfonline.com
    Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade
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      RRID:CVCL_0004

      DOI: 10.1080/2162402X.2022.2068109

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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
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  163. Apr 2022
  164. www.tandfonline.com www.tandfonline.com
    Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade
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      RRID:CVCL_0004

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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockade of inhibitory killer cell immunoglobulin-like receptors and IL-2 triggering reverses the functional hypoactivity of tumor-derived NK-cells in glioblastomas
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrating transcription-factor abundance with chromatin accessibility in human erythroid lineage commitment
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  167. www-sciencedirect-com.ezp-prod1.hul.harvard.edu www-sciencedirect-com.ezp-prod1.hul.harvard.edu
    Modular design of synthetic receptors for programmed gene regulation in cell therapies
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  168. www.sciencedirect.com www.sciencedirect.com
    Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
    2
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  169. www.sciencedirect.com www.sciencedirect.com
    Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
    2
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  170. aacrjournals.org aacrjournals.org
    EBV infection in epithelial malignancies induces resistance to antitumor natural killer cells via F3-mediated platelet aggregation
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  171. academic.oup.com academic.oup.com
    RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history
    1
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    academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkac054/6543614
  172. www.cell.com www.cell.com
    Facile discovery of surrogate cytokine agonists
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      ATCCCat#CCL-243

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    cell.com/cell/fulltext/S0092-8674(22)00247-1
  173. www.nature.com www.nature.com
    Transcriptome-wide identification of RNA-binding protein binding sites using seCLIP-seq
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced NK Cell Cytotoxicity by Papillomatosis-Derived TGF-β Contributing to Low-Risk HPV Persistence in JORRP Patients
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      DOI: 10.3389/fimmu.2022.849493

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  175. Mar 2022
  176. www.sciencedirect.com www.sciencedirect.com
    High-throughput characterization of the role of non-B DNA motifs on promoter function
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  177. link.springer.com link.springer.com
    Tumour cell-activated platelets modulate the immunological activity of CD4+, CD8+, and NK cells, which is efficiently antagonized by heparin
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SHP-1 activity by PKC-θ regulates NK cell activation threshold and cytotoxicity
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      DOI: 10.7554/eLife.73282

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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A test of the pioneer factor hypothesis using ectopic liver gene activation
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      DOI: 10.7554/eLife.73358

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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tofacitinib Suppresses Natural Killer Cells In Vitro and In Vivo: Implications for Amyotrophic Lateral Sclerosis
    1
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  181. Feb 2022
  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunomodulatory potential of in vivo natural killer T (NKT) activation by NKTT320 in Mauritian-origin cynomolgus macaques
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      RRID:CVCL_0004

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  183. www.sciencedirect.com www.sciencedirect.com
    Gene architecture directs splicing outcome in separate nuclear spatial regions
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  184. www.nature.com www.nature.com
    Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The E3 protein ubiquitin ligase Itch is a potential target in myeloid malignancies with marrow fibrosis
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  186. www.nature.com www.nature.com
    Efficient recovery of potent tumour-infiltrating lymphocytes through quantitative immunomagnetic cell sorting
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a Novel Anti-CD19 CAR Containing a Fully Human scFv and Three Costimulatory Domains
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  188. www.sciencedirect.com www.sciencedirect.com
    An oncogenic enhancer encodes selective selenium dependency in AML
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      ATCCCCL-243

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  189. Jan 2022
  190. link.springer.com link.springer.com
    Novel inhibitor of hematopoietic cell kinase as a potential therapeutic agent for acute myeloid leukemia
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      DOI: 10.1007/s00262-021-03111-2

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  191. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    1
    1. scibot 12 Jan 2022
      CCL-243

      DOI: 10.1016/j.celrep.2021.110233

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    sciencedirect.com/science/article/pii/S2211124721017423
  192. www.sciencedirect.com www.sciencedirect.com
    Identification and functional characterization of transcriptional activators in human cells
    1
    1. scibot 11 Jan 2022
      CCL-243

      DOI: 10.1016/j.molcel.2021.12.008

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    sciencedirect.com/science/article/pii/S1097276521010704
  193. Dec 2021
  194. www.sciencedirect.com www.sciencedirect.com
    Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity
    1
    1. scibot 23 Dec 2021
      RRID:CVCL_0004

      DOI: 10.1016/j.molcel.2021.11.032

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  195. www.sciencedirect.com www.sciencedirect.com
    HLA-A∗02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses
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      RRID:CVCL_0004

      DOI: 10.1016/j.celrep.2021.110167

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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-Tumor Activity of Expanded PBMC-Derived NK Cells by Feeder-Free Protocol in Ovarian Cancer
    1
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      RRID:CVCL_0004

      DOI: 10.3390/cancers13225866

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    ncbi.nlm.nih.gov/pmc/articles/PMC8616155/
  197. Nov 2021
  198. www.sciencedirect.com www.sciencedirect.com
    Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling
    1
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      CCL-243

      DOI: 10.1016/j.celrep.2021.110036

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    sciencedirect.com/science/article/pii/S2211124721015187
  199. mct.aacrjournals.org mct.aacrjournals.org
    SAGE1: a Potential Target Antigen for Lung Cancer T-Cell Immunotherapy
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      DOI: 10.1158/1535-7163.MCT-21-0203

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    mct.aacrjournals.org/content/20/11/2302
  200. www.sciencedirect.com www.sciencedirect.com
    Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy
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      CCL-243

      DOI: 10.1016/j.xcrm.2021.100449

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    sciencedirect.com/science/article/pii/S2666379121003177
  201. www.nature.com www.nature.com
    AKIRIN2 controls the nuclear import of proteasomes in vertebrates
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      RRID:CVCL_0004

      DOI: 10.1038/s41586-021-04035-8

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    nature.com/articles/s41586-021-04035-8
  202. Oct 2021
  203. www.sciencedirect.com www.sciencedirect.com
    Generation and validation of CRISPR-engineered human natural killer cell lines for research and therapeutic applications
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      CCL-243

      DOI: 10.1016/j.xpro.2021.100874

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  204. www.sciencedirect.com www.sciencedirect.com
    NKG2A expression identifies a subset of human Vδ2 T cells exerting the highest antitumor effector functions
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      CCL-243

      DOI: 10.1016/j.celrep.2021.109871

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  205. www.sciencedirect.com www.sciencedirect.com
    Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates
    1
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      CCL-243

      DOI: 10.1016/j.molcel.2021.09.021

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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines
    1
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      CVCL_0004

      DOI: 10.1038/s41598-021-98869-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC8484624/
  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD34+ progenitor-derived NK cell and gemcitabine combination therapy increases killing of ovarian cancer cells in NOD/SCID/IL2Rgnull mice
    1
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      RRID:CVCL_0004

      DOI: 10.1080/2162402X.2021.1981049

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    ncbi.nlm.nih.gov/pmc/articles/PMC8489932/
  208. Sep 2021
  209. www.sciencedirect.com www.sciencedirect.com
    Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
    1
    1. scibot 22 Sep 2021
      RRID:CVCL_0004

      DOI: 10.1016/j.celrep.2021.109725

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    sciencedirect.com/science/article/pii/S2211124721011748
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lentiviral-driven discovery of cancer drug resistance mutations
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    1. scibot 22 Sep 2021
      RRID:CVCL_0004

      DOI: 10.1158/0008-5472.CAN-21-1153

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    ncbi.nlm.nih.gov/pmc/articles/PMC8448967/
  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
    1
    1. scibot 11 Sep 2021
      RRID:CVCL_0004

      DOI: 10.7554/eLife.69142

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    ncbi.nlm.nih.gov/pmc/articles/PMC8423448/
  212. www.sciencedirect.com www.sciencedirect.com
    High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
    1
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      CCL-243

      DOI: 10.1016/j.celrep.2021.109632

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  213. www.sciencedirect.com www.sciencedirect.com
    Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice
    1
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      CCL-243

      DOI: 10.1016/j.celrep.2021.109626

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    sciencedirect.com/science/article/pii/S2211124721010640
  214. www.sciencedirect.com www.sciencedirect.com
    A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
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      RRID:CVCL_0004

      DOI: 10.1016/j.chembiol.2021.08.004

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    sciencedirect.com/science/article/pii/S2451945621003937
  215. Aug 2021
  216. www.sciencedirect.com www.sciencedirect.com
    fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins
    1
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      CCL-243

      DOI: 10.1016/j.xpro.2021.100762

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    sciencedirect.com/science/article/pii/S2666166721004688
  217. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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      RRID:CVCL_0004

      DOI: 10.7554/eLife.64148

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    elifesciences.org/articles/64148
  218. www.sciencedirect.com www.sciencedirect.com
    Methylation of dual-specificity phosphatase 4 controls cell differentiation
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      RRID:CVCL_0004

      DOI: 10.1016/j.celrep.2021.109421

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    sciencedirect.com/science/article/pii/S2211124721008342
  219. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:CVCL_0004

      DOI: 10.1016/j.stem.2019.02.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6458988/
  220. www.sciencedirect.com www.sciencedirect.com
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      RRID:CVCL_0004

      DOI: 10.1016/j.cell.2019.03.009

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    sciencedirect.com/science/article/pii/S0092867419302715
  221. www.tandfonline.com www.tandfonline.com
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      RRID:CVCL_0004

      DOI: 10.1080/15384047.2018.1504722

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    tandfonline.com/doi/abs/10.1080/15384047.2018.1504722
  222. www.sciencedirect.com www.sciencedirect.com
    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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      CCL-243

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    sciencedirect.com/science/article/pii/S2211124721009463
  223. www.sciencedirect.com www.sciencedirect.com
    Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation
    1
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      RRID:CVCL_0004

      DOI: 10.1016/j.ccell.2018.11.017

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    sciencedirect.com/science/article/pii/S1535610818305385
  224. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia
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      RRID:CVCL_0004

      DOI: 10.1016/j.ccell.2018.11.002

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  225. www.sciencedirect.com www.sciencedirect.com
    A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response
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      CVCL_0004

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    sciencedirect.com/science/article/pii/S0092867416316609
  226. www.sciencedirect.com www.sciencedirect.com
    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
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      CCL-243

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  227. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:CVCL_0004

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  228. www.sciencedirect.com www.sciencedirect.com
    A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates
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      RRID:CVCL_0004

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  229. www.nature.com www.nature.com
    A plate-based single-cell ATAC-seq workflow for fast and robust profiling of chromatin accessibility
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      DOI: 10.1038/s41596-021-00583-5

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  230. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Counteracting the effect of leukemia exosomes by antiangiogenic gold nanoparticles
    1
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      RRID:CVCL_0004

      DOI: 10.2147/IJN.S215711

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  231. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Small Molecular Modulators of JMJD1C Preferentially Inhibit Growth of Leukemia Cells
    1
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      DOI: 10.1002/ijc.32552

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    onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32552
  232. Jul 2021
  233. www.sciencedirect.com www.sciencedirect.com
    A BRD4-mediated elongation control point primes transcribing RNA polymerase II for 3′-processing and termination
    1
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      CCL-243

      DOI: 10.1016/j.molcel.2021.06.026

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  234. www.sciencedirect.com www.sciencedirect.com
    Splicing Kinetics and Coordination Revealed by Direct Nascent RNA Sequencing through Nanopores
    1
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      Human K562 cells

      DOI: 10.1016/j.molcel.2019.11.017

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    sciencedirect.com/science/article/pii/S1097276519308652
  235. www.sciencedirect.com www.sciencedirect.com
    A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia
    1
    1. scibot 31 Jul 2021
      Human: K562

      DOI: 10.1016/j.ccell.2019.11.001

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    sciencedirect.com/science/article/pii/S1535610819305215
  236. www.sciencedirect.com www.sciencedirect.com
    A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering
    1
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      K562

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