527 Matching Annotations
  1. Aug 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1,2,4‐Triazole‐Acetamide Conjugates as hEGFR Inhibitors: Synthesis, Anticancer Evaluation, and In Silico Studies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13419370/
  3. Jul 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synergistic cooperation between progranulin and Jak2/Stat3 signaling determines definitive myeloid cell fate
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    pmc.ncbi.nlm.nih.gov/articles/PMC13366427/
  5. www.biorxiv.org www.biorxiv.org
    Isoform-level resolution in single-cell CRISPR screens reveals hidden functional consequences of gene perturbation
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    biorxiv.org/content/10.64898/2026.07.09.737410v1
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    Hypoxia rescues complex 1-associated disease caused by proteostatic defects
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    nature.com/articles/s42255-026-01566-0
  7. aacrjournals.org aacrjournals.org
    Cancer Susceptibility to Stapled Oncolytic Peptides is Dictated by Membrane Cholesterol and Inflammatory Signaling
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    aacrjournals.org/cancerres/article/86/11/2810/785298/Cancer-Susceptibility-to-Stapled-Oncolytic
  8. 54.241.53.176 54.241.53.176
    Optimizing Zirconium-89 labeling for chimeric antigen receptor T cell PET imaging by comparing desferrioxamine and oxine
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    54.241.53.176/b98ef7d0151aa3326e9a2ff582d132dc284f94aa/s41598-026-51355-8_reference-html.html
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70403
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    Genome-wide rotational and translational phasing of nucleosomes with human transcription factors
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    sciencedirect.com/science/article/pii/S1097276526003904
  11. Jun 2026
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    Dual inhibition of tubulin and DNMT by the novel letermovir derivative H62 blocks leukemia
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    sciencedirect.com/science/article/pii/S0006295226005356
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    Dynamic UFMylation governs cellular fitness by coordinating multi-organelle proteostasis
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    biorxiv.org/content/10.64898/2026.03.27.714830v1
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    Autosomal dominant CDC45 deficiency with allelic expression bias causes a novel genetic disease of the immune system
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    biorxiv.org/content/10.64898/2026.03.04.709645v1
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    Tubular basement membrane damage promotes renal fibrosis via an ETV5/TGFB1/SOX9 axis in proximal tubular epithelial cells after acute kidney injury
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    sciencedirect.com/science/article/pii/S0898656826003396
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    The activity of EGFR CAR-NK and CAR-T cells against EGFR inhibitor-resistant NSCLC and drug-tolerant persister cells
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    aacrjournals.org/clincancerres/article/31/22/4745/767041/The-Activity-of-EGFR-CAR-NK-and-CAR-T-Cells
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of CAR T cells Targeting a Surface RNA Binding Protein for the Treatment of Acute Leukemias
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    pmc.ncbi.nlm.nih.gov/articles/PMC13271017/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structurally exclusive Teneurin complexes orchestrate divergent programs in early cortical development
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    pmc.ncbi.nlm.nih.gov/articles/PMC13269823/
  19. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Mechanistic Insights Into Efficient Intracellular Delivery via a High-Precision Piezoelectric-Nanoneedle Microfluidic Platform
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    advanced.onlinelibrary.wiley.com/doi/10.1002/admt.71116
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    Cassane-Type Diterpenoids From the Seeds of Caesalpinia pulcherrima and Their Cytotoxic Activities
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71395
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    A New Sulfated Cholestane From the Sea Urchin Mesocentrotus nudus With Cytotoxic Activity
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71393
  22. May 2026
  23. www.sciencedirect.com www.sciencedirect.com
    Enhanced formaldehyde clearance ameliorates differentiation-induced genotoxicity in Fanconi anemia mutant cells
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    sciencedirect.com/science/article/pii/S2211124726005279
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A high-throughput modular microfluidic platform for versatile functional assays at single-cell level
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    pmc.ncbi.nlm.nih.gov/articles/PMC13184078/
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    USP22 Inhibition Potentiates GPC3 Chimeric Antigen Receptor Macrophages Efficacy in Hepatocellular Carcinoma by Downregulating Tumor CD24 Expression
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    sciencedirect.com/science/article/pii/S0304383526003563
  26. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cytotoxic Profiling of 3′,4′,5′-Trimethoxychalcones Reveals Cell-Line-Dependent Cytotoxic Activity: An In Vitro and In Silico Study
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    onlinelibrary.wiley.com/doi/full/10.1002/cbdv.71336
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    Expansion of NKG2A+CD8+ T cells with regulatory signatures distinguish individuals living with HIV-2 from those with HIV-1
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    sciencedirect.com/science/article/pii/S2666634026001467
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    Ecological determinants of disease and immunity in myelodysplastic syndromes
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    biorxiv.org/content/10.64898/2026.05.05.720208v1
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    Trichostatin Analogues From the Karst Cave Associated Streptomyces sp. DX6D14
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71334
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell shapes decode molecular phenotypes in image-based spatial proteomics
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  31. aacrjournals.org aacrjournals.org
    Constitutive STAT3 signaling, in comparison to STAT5, enhances CAR T cell efficacy and lowers systemic toxicity
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    aacrjournals.org/cancerimmunolres/article/14/5/845/784457/Constitutive-STAT3-Signaling-in-Comparison-with
  32. www.nature.com www.nature.com
    Peptide-centric local stability assay (PELSA) for sensitive identification of ligand-targeting proteins and binding sites at proteome scale
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    NK cell dysfunction and interferon gamma production underlie autoinflammation in mevalonate kinase deficiency
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    sciencedirect.com/science/article/pii/S107476132600138X
  34. Apr 2026
  35. www.biorxiv.org www.biorxiv.org
    PKA–CIP4 SIGNALING REGULATES CIP4 RELOCATION IN ACTIVATED NATURAL KILLER CELLS
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    biorxiv.org/content/10.64898/2026.04.22.720117v1
  36. aacrjournals.org aacrjournals.org
    The allogeneic FAP-CAR-IL15 iNKT therapy MiNK-215 remodels the tumor stroma to enhance antitumor immunity
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    aacrjournals.org/cancerimmunolres/article/14/2/243/771961/The-Allogeneic-FAP-CAR-IL15-iNKT-Therapy-MiNK-215
  37. aacrjournals.org aacrjournals.org
    Harnessing Notch Signaling to Enhance the Generation and Functionality of Human Conventional Type I Dendritic Cells for Cancer Immunotherapy Applications
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    aacrjournals.org/cancerimmunolres/article/13/9/1328/764171/Harnessing-Notch-Signaling-to-Enhance-the
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    TIGIT affects CAR NK cell effector function in the solid tumor microenvironment by modulating immune synapse strength
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    aacrjournals.org/cancerimmunolres/article/13/10/1576/765472/TIGIT-Affects-CAR-NK-cell-Effector-Function-in-the
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    LRRTM4 controls cell migration via Glypican interactions
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    biorxiv.org/content/10.64898/2026.04.14.718450v1
  40. www.nature.com www.nature.com
    Discovery of an Endonuclease G-inhibitory Ku80-peptide protecting against leukemogenic rearrangements at the MLL breakpoint cluster
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    nature.com/articles/s41467-026-72034-2
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Base Editing of TIGIT Reprograms CD155 Signaling in Natural Killer Cells to Enhance Cancer Immunotherapy Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13080321/
  42. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    An Artificial Antibody-Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515707
  43. 54.241.53.176 54.241.53.176
    A Fully Human Pan VL9 HLAE TCRm Antibody Enables Functional Dissection of HLAE Biology and Checkpoint Signaling
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  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055633/
  45. www.tandfonline.com www.tandfonline.com
    Sialic acid cis-ligand dynamics modulate Siglec-7 and -9 function and affect Siglec-7/9 co-blockade to potentiate natural killer cell anti-tumor activity
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    tandfonline.com/doi/full/10.1080/2162402X.2026.2649988
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture
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    pmc.ncbi.nlm.nih.gov/articles/PMC13040219/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042807/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UVI5008: the first reversible, non-covalent Bruton’s tyrosine kinase epi-inhibitor for B-cell malignancies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13032278/
  49. Mar 2026
  50. www.sciencedirect.com www.sciencedirect.com
    Reshaping the progranulin/sortilin interaction for targeted degradation of extracellular proteins
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    sciencedirect.com/science/article/pii/S2451945626000723
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    Shear stress-induced Piezo1 activates CD99L2 to facilitate the initiation of blood circulation
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    sciencedirect.com/science/article/pii/S2211124726002780
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD70-Targeting CAR NK Cells Overcome BCMA Downregulation and Improve Survival in High-risk Multiple Myeloma Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012245/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The murine MHC-E molecule Qa-1b is surface displayed in a peptide-free conformation in homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13006831/
  54. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.70316
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chemical Constituents of Taxodium mucronatum (Cupressaceae) and Some of Its Endophytic Fungi, and Their In Silico and In Vitro Evaluations as SARS‐CoV‐2 Inhibitors and as Cytotoxic Agents
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    pmc.ncbi.nlm.nih.gov/articles/PMC12983190/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12953771/
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    FASN inactivation-induced progranulin (GRN) expression promotes lysosome-dependent cell death to suppress leukemogenesis
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    sciencedirect.com/science/article/pii/S2211124726001208
  58. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    BCR::ABL1-Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B-ALL Cells to Enhancer-Targeting Drugs
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202517231
  59. Feb 2026
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional regulation of GlycoRNA and progress in malignant tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12930660/
  61. www.sciencedirect.com www.sciencedirect.com
    Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity
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    sciencedirect.com/science/article/pii/S193459092600038X
  62. www.sciencedirect.com www.sciencedirect.com
    Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease
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    sciencedirect.com/science/article/pii/S0092867426001091
  63. www.sciencedirect.com www.sciencedirect.com
    Functional nutrient-genetic profiling reveals biotin and FBXW7 are essential to bypass glutamine addiction
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    sciencedirect.com/science/article/pii/S1097276526000973
  64. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70226
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12922744/
  66. www.science.org www.science.org
    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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    science.org/doi/10.1126/sciadv.aea2511
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    BRD4-mediated ER membrane contact creates functionally distinct mitochondrial subtypes
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    sciencedirect.com/science/article/pii/S1097276526000328
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    ACSL4-associated lipid metabolism is a distinct therapeutic vulnerability in KMT2A-rearranged acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S2211124726000884
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    The transcriptional repressor Fli1 inhibits proteostasis during nutrient stress to limit NK cell persistence in solid tumors
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    sciencedirect.com/science/article/pii/S107476132600035X
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    Multichannel genomic recording of biological information with ENGRAM
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    nature.com/articles/s41596-025-01322-w
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70422
  72. 54.241.53.176 54.241.53.176
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  73. www.biorxiv.org www.biorxiv.org
    Spatial mapping of RNA turnover kinetics and regulatory landscapes of mRNA stability in the mammalian brain
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    biorxiv.org/content/10.64898/2026.01.29.702431v1
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    Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate tumors
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    sciencedirect.com/science/article/pii/S2666379125006184
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    Integrating natural and engineered genetic variations to decode regulatory influence on blood traits
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    sciencedirect.com/science/article/pii/S221112472600015X
  76. Jan 2026
  77. www.biorxiv.org www.biorxiv.org
    NK Cells Engineered with a Chimeric Antigen Receptor Delay HIV Rebound and Reshape HIV Reservoir Composition
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    biorxiv.org/content/10.64898/2026.01.22.700964v1
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    CRISPR activation screens map the genomic landscape of cancer glycome remodeling
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    sciencedirect.com/science/article/pii/S2666979X26000017
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70191
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    Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
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    sciencedirect.com/science/article/pii/S2666379125006500
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a lipid oxygen radical defense pathway and its epigenetic control
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    pmc.ncbi.nlm.nih.gov/articles/PMC12820049/
  82. www.nature.com www.nature.com
    Single-nucleus chromatin accessibility and gene expression co-profiling by ISSAAC-seq
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    nature.com/articles/s41596-025-01304-y
  83. elifesciences.org elifesciences.org
    Nonlinear transcriptional responses to gradual modulation of transcription factor dosage
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    elifesciences.org/articles/100555
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tandem Duplications in UBTF Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
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    pmc.ncbi.nlm.nih.gov/articles/PMC12793833/
  85. www.biorxiv.org www.biorxiv.org
    MYST acetyltransferases are a targetable therapeutic vulnerability in SETBP1-mutant leukemia
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    biorxiv.org/content/10.64898/2026.01.08.697228v1
  86. Dec 2025
  87. www.science.org www.science.org
    Unconventional CD8+ T cell surveillance of cytomegalovirus via Qa-1/HLA-E–restricted epitope recognition
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    science.org/doi/10.1126/sciadv.aea8707
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated scFv identification and CAR T cell generation for AML targeting in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC12712367/
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Machine learning-based development of a cytotoxicity prediction model for NK cell therapy in cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12698772/
  90. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma
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    sciencedirect.com:5037/science/article/pii/S1535610825004908
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CAR binders affect CAR T-cell tonic signaling, durability, and sensitivity to target
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137003/
  92. 54.241.53.176 54.241.53.176
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  190. Nov 2024
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  221. Jun 2024
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