274 Matching Annotations
  1. Sep 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Notch3 mediated TGF-β1 activation enhances epithelial-mesenchymal transition and cancer stemness in non-small lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12370359/
  3. www.sciencedirect.com www.sciencedirect.com
    Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response
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    sciencedirect.com/science/article/pii/S1097276525006641
  4. www.sciencedirect.com www.sciencedirect.com
    Host cell entry efficiency and neutralization sensitivity of the SARS-CoV-2 MC.10.1 variant
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    sciencedirect.com/science/article/pii/S0042682225002892
  5. Aug 2025
  6. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    DACT3-DVL1 Interaction-Mediated Canonical WNT Signaling Regulates Non-Small Cell Lung Cancer Progression and Cisplatin Resistance
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202501462RR
  7. www.authorea.com www.authorea.com
    APOA1 as a Potential Therapeutic Target and Novel Biomarker in Lung Adenocarcinoma
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    authorea.com/users/954518/articles/1323515-apoa1-as-a-potential-therapeutic-target-and-novel-biomarker-in-lung-adenocarcinoma
  8. www.sciencedirect.com www.sciencedirect.com
    53BP1 regulates p53-E2F7-dependent transcriptional gene repression and participates in the Fanconi anemia pathway
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    sciencedirect.com/science/article/pii/S2211124725009234
  9. www.sciencedirect.com www.sciencedirect.com
    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FBXW5 Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Through the KLF13/TROAP Signaling Pathway
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.70018
  11. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Dominant-Negative Effects of p53 R337 Variants in Li–Fraumeni Syndrome: Impact on Tetramer Formation and Transcriptional Activity
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    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.202500330
  12. Jul 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12289886/
  14. link.springer.com link.springer.com
    High PER1 expression is associated with STK11 mutation and clinical biomarkers of immunotherapy resistance in lung adenocarcinoma
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    link.springer.com/article/10.1007/s00432-025-06269-9
  15. elifesciences.org elifesciences.org
    Δ133p53α and Δ160p53α isoforms of the tumor suppressor protein p53 exert dominant-negative effect primarily by co-aggregation
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    elifesciences.org/articles/106469
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Utility of CK8/18 in identifying circulating tumor cells derived from lesions in patients with non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12261347/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12257754/
  18. www.sciencedirect.com www.sciencedirect.com
    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1535610825002612
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232590/
  20. www.sciencedirect.com www.sciencedirect.com
    Rbpms2 prevents major cardiac defects in cardiomyocyte-specific Rbpms-deficient mice
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    sciencedirect.com/science/article/pii/S1534580725003685
  21. Jun 2025
  22. www.authorea.com www.authorea.com
    Harmine inhibits non-small cell lung cancer growth by targeting PDE4D and inducing ferroptosis
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    authorea.com/users/934552/articles/1305055-harmine-inhibits-non-small-cell-lung-cancer-growth-by-targeting-pde4d-and-inducing-ferroptosis
  23. 52.53.155.43 52.53.155.43
    An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
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    52.53.155.43/2a376853a698c82918e819c120184e6f0c636097/gkaf532-html.html
  24. link.springer.com link.springer.com
    The puzzling regulation of the interferon signaling system by the p53 tumor suppressor protein
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    link.springer.com/article/10.1007/s00018-025-05763-0
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12127800/
  26. link.springer.com link.springer.com
    PIN1 serves as a prognostic and therapeutic biomarker in lung adenocarcinoma
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    link.springer.com/article/10.1007/s10142-025-01629-7
  27. May 2025
  28. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/76052131b420a79d64f86d012d13a41695e401e2/PDF-html.html
  29. link.springer.com link.springer.com
    NECTIN4 regulates the cell surface expression of CD155 in non-small cell lung cancer cells and induces tumor resistance to PD-1 inhibitors
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    link.springer.com/article/10.1007/s00262-025-04079-z
  30. www.sciencedirect.com www.sciencedirect.com
    MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725004930
  31. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    FAT1 Enhances the Sensitivity of Non-Small Cell Lung Cancer to VCP Inhibitors by Regulating the Activation of the Endoplasmic Reticulum Stress Pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500097RR
  32. link.springer.com link.springer.com
    Tumor cell-intrinsic circular RNA circFNDC3B attenuates CD8+ T cells infiltration in non-small cell lung cancer
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    link.springer.com/article/10.1038/s42003-025-08108-6
  33. Apr 2025
  34. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Aberrant expression of nuclear prothymosin α contributes to epithelial-mesenchymal transition in lung cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70035
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EFTUD2 is a promising diagnostic and prognostic indicator involved in the tumor immune microenvironment and glycolysis of lung adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11996642/
  36. www.sciencedirect.com www.sciencedirect.com
    Combined inhibition of hexokinase 2 and pyruvate dehydrogenase surmounts SHP2 inhibitor resistance in non-small cell lung cancer with hybrid metabolic state harboring KRAS Q61H mutation
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    sciencedirect.com/science/article/pii/S0925443925002042
  37. 52.53.155.43 52.53.155.43
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  38. www.sciencedirect.com www.sciencedirect.com
    Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies
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    sciencedirect.com/science/article/pii/S1534580725001558
  39. www.nature.com www.nature.com
    Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage
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    nature.com/articles/s41420-025-02441-9
  40. Mar 2025
  41. www.sciencedirect.com www.sciencedirect.com
    A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0092867425002910
  42. www.cell.com www.cell.com
    Lactylation orchestrates ubiquitin-independent degradation of cGAS and promotes tumor growth
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    cell.com/cell-reports/fulltext/S2211-1247(25)00212-8
  43. www.sciencedirect.com www.sciencedirect.com
    SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
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    sciencedirect.com/science/article/pii/S1097276525001091
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery and characterization of a novel telomerase alternative splicing isoform that protects lung cancer cells from chemotherapy induced cell death
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    pmc.ncbi.nlm.nih.gov/articles/PMC11861669/
  45. Feb 2025
  46. translational-medicine.biomedcentral.com translational-medicine.biomedcentral.com
    JMJD6 K375 acetylation restrains lung cancer progression by enhancing METTL14/m6A/SLC3A2 axis mediated cell ferroptosis
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    translational-medicine.biomedcentral.com/articles/10.1186/s12967-025-06241-8
  47. aacrjournals.org aacrjournals.org
    Targeting Tumor-Associated Sialic Acids using Chimeric Switch Receptors based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
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    aacrjournals.org/cancerimmunolres/article/12/10/1380/748721/Targeting-Tumor-Associated-Sialic-Acids-Using
  48. www.sciencedirect.com www.sciencedirect.com
    Synonymous mutations promote tumorigenesis by disrupting m6A-dependent mRNA metabolism
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    sciencedirect.com/science/article/pii/S0092867425000959
  49. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of SIRT7 by ATM causes DNA mismatch repair downregulation and adaptive mutability during chemotherapy
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    sciencedirect.com/science/article/pii/S2211124725000403
  50. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability
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    cellandbioscience.biomedcentral.com/articles/10.1186/s13578-025-01358-1
  51. Jan 2025
  52. www.nature.com www.nature.com
    Photothermal nanofiber-mediated photoporation for gentle and efficient intracellular delivery of macromolecules
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    nature.com/articles/s41596-024-01115-7
  53. www.sciencedirect.com www.sciencedirect.com
    Mina53 catalyzes arginine demethylation of p53 to promote tumor growth
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    sciencedirect.com/science/article/pii/S2211124725000130
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11748778/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11701801/
  56. www.sciencedirect.com www.sciencedirect.com
    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    sciencedirect.com/science/article/pii/S1074761324005685
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11668523/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Demethylzeylasteral inhibits oxidative phosphorylation complex biogenesis by targeting LRPPRC in lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11660126/
  59. Dec 2024
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography
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    pmc.ncbi.nlm.nih.gov/articles/PMC11652680/
  61. www.cell.com www.cell.com
    Pan-cancer analysis of biallelic inactivation in tumor suppressor genes identifies KEAP1 zygosity as a predictive biomarker in lung cancer
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    cell.com/cell/fulltext/S0092-8674(24)01327-8
  62. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13773
  63. www.sciencedirect.com www.sciencedirect.com
    The ATAC complex represses the transcriptional program of the autophagy-lysosome pathway via its E3 ubiquitin ligase activity
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    sciencedirect.com/science/article/pii/S2211124724013846
  64. www.sciencedirect.com www.sciencedirect.com
    p53 induces circFRMD4A to suppress cancer development through glycolytic reprogramming and cuproptosis
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    sciencedirect.com/science/article/pii/S1097276524009183
  65. www.sciencedirect.com www.sciencedirect.com
    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124724013779
  66. www.sciencedirect.com www.sciencedirect.com
    Lovastatin-mediated pharmacological inhibition of Formin protein DIAPH1 suppresses tumor immune escape and boosts immunotherapy response
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    sciencedirect.com/science/article/pii/S1567576924021593
  67. Nov 2024
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chelating drug-induced labile Zn2+ with nanoparticle-encapsulated TPEN at low dose enhances lung cancer chemotherapy through inhibiting ABCB1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539588/
  69. 52.53.155.43 52.53.155.43
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    52.53.155.43/4faeafb6ce934469a644c8bc705adf42bb41b860/can-24-0529-html.html
  70. Oct 2024
  71. www.sciencedirect.com www.sciencedirect.com
    Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
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    sciencedirect.com/science/article/pii/S2451945624003969
  72. link.springer.com link.springer.com
    Inhibition of EREG/ErbB/ERK by Astragaloside IV reversed taxol-resistance of non-small cell lung cancer through attenuation of stemness via TGFβ and Hedgehog signal pathway
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    link.springer.com/article/10.1007/s13402-024-00999-7
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443317/
  74. Sep 2024
  75. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13705
  76. www.sciencedirect.com www.sciencedirect.com
    CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway
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    sciencedirect.com/science/article/pii/S2589004224020571
  77. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11365971/
  79. Aug 2024
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptomics Reveals the Mechanism of Platycodin D Targeting TGFβ for Anti-Lung Cancer Activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11350543/
  81. www.sciencedirect.com www.sciencedirect.com
    The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress
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    sciencedirect.com/science/article/pii/S2211124724009604
  82. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Pan-html.html
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    52.53.155.43/0c03bb3198bd7f61266aaeb6cf8a257d677212b0/Molecular Oncology - 2023 - Pan-html.html
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of IDH3α Enhanced the Efficacy of Chemoimmunotherapy by Regulating Acidic Tumor Microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10046804/
  84. www.tandfonline.com www.tandfonline.com
    Comprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental Validation
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    tandfonline.com/doi/abs/10.2147/JIR.S399193
  85. elifesciences.org elifesciences.org
    Decoupling global biases and local interactions between cell biological variables
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    elifesciences.org/content/6/e22323
  86. Jul 2024
  87. www.sciencedirect.com www.sciencedirect.com
    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    sciencedirect.com/science/article/pii/S1535610824002174
  88. www.sciencedirect.com www.sciencedirect.com
    Target fishing and mechanistic insights of the natural anticancer drug candidate chlorogenic acid
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    sciencedirect.com/science/article/pii/S221138352400265X
  89. May 2024
  90. aacrjournals.org aacrjournals.org
    Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma
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    aacrjournals.org/cancerres/article/84/10/1570/745316/Bile-Acid-Metabolism-Mediates-Cholesterol
  91. aacrjournals.org aacrjournals.org
    Cooperative armoring of CAR and TCR T-cells by T cell-restricted IL-15 and IL-21 universally enhances solid tumor efficacy
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    aacrjournals.org/clincancerres/article/30/8/1555/742121/Cooperative-Armoring-of-CAR-and-TCR-T-Cells-by-T
  92. aacrjournals.org aacrjournals.org
    TNFRSF19 within the 13q12.12 risk locus functions as a lung cancer suppressor by binding Wnt3a to inhibit Wnt/β-catenin signaling.
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    aacrjournals.org/mcr/article/22/3/227/734703/TNFRSF19-within-the-13q12-12-Risk-Locus-Functions
  93. www.sciencedirect.com www.sciencedirect.com
    Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
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    sciencedirect.com/science/article/pii/S1550413124001384
  94. 52.53.155.43 52.53.155.43
    Therapeutic Implications of Ceritinib in Cholangiocarcinoma beyond ALK Expression and Mutation
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    52.53.155.43/3f07be0ebaa016d2b81ff2554651fc11f237f3a0/pharmaceuticals-17-00197-html.html
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy of EGFR and AURKA Inhibitors in KRAS-mutated Non–small Cell Lung Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078142/
  96. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
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    52.53.155.43/761c70660e3a03a822484173742c13c4c44cc6bf/PIIS2589004224010915-html.html
  97. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Disrupting the interaction between a p53 gain-of-function mutant and the transcriptional co-activator PC4 reverses drug resistance in cancer cells
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14890
  98. Apr 2024
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    The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
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